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ClinicalTrials.gov public records Last synced Oct 15, 2026, 1:21 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 361–384 of 634 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Complications of Prematurity Clear all
Recruiting No phase listed Observational Accepts healthy volunteers

Advancing Stillbirth Prevention Through Innovative Risk Evaluation (ASPIRE) Clinical Study

NCT07669935
View directory record Official record
Conditions
GDM, Preterm Preeclampsia, Preeclampsia, Fetal Growth Restriction (FGR), Pregnancy Complications
Interventions
None (this is an observational study with no intervention)
Other
Lead sponsor
Medicines360
Other
Eligibility
18 Years to 99 Years · Female only
Enrollment
5,500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
2
States / cities
Baton Rouge, Louisiana • Potsdam, New York
Source: ClinicalTrials.gov public record
Updated Sep 30, 2026 · Synced Oct 15, 2026, 1:21 AM EDT
Completed No phase listed Observational

Urine Concentration of S100B in Extremely Premature Infants

NCT00747591
View directory record Official record
Conditions
Premature Infants
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
Up to 7 Days
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2005
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Jul 23, 2010 · Synced Oct 15, 2026, 1:21 AM EDT
Completed Not applicable Interventional

Effect of Protein Intake on Preterm Infant Body Composition

NCT02353013
View directory record Official record
Conditions
Premature; Infant, Light-for-dates
Interventions
Protein supplementation, Standard fortification
Dietary Supplement
Lead sponsor
University of Oklahoma
Other
Eligibility
1 Minute to 1 Year
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Dec 22, 2017 · Synced Oct 15, 2026, 1:21 AM EDT
Completed Phase 3 Interventional

Follow-up at School-age of Children Who Participated in the Efficacy Study of Nitric Oxide for Premature Infants

NCT00152542
View directory record Official record
Conditions
Prematurity, Respiratory Distress Syndrome,Hypoxemia
Interventions
Inhaled nitric oxide, Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
4 Years to 6 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 12, 2013 · Synced Oct 15, 2026, 1:21 AM EDT
Recruiting No phase listed Observational

Clinical Safety Guidelines for Managing Distal Shoe Complications

NCT07410442
View directory record Official record
Conditions
Premature Loss of Primary Molars, Space Maintainer, Soft Tissue Inflammation
Interventions
Standard Clinical Practice Regimen
Other
Lead sponsor
University of Florida
Other
Eligibility
3 Years to 9 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 15, 2026, 1:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intrapartum Study of Sterile and Clean Gloves

NCT01852188
View directory record Official record
Conditions
Chorioamnionitis
Interventions
Type of glove used for intrapartum vaginal exams
Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older · Female only
Enrollment
507 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2014
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 18, 2018 · Synced Oct 15, 2026, 1:21 AM EDT
Completed Not applicable Interventional

A RCT of CenteringPregnancy on Birth Outcomes

NCT02640638
View directory record Official record
Conditions
Pregnancy, Preterm Birth
Interventions
CenteringPregnancy
Behavioral
Lead sponsor
Clemson University
Other
Eligibility
14 Years to 45 Years · Female only
Enrollment
2,350 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
4
States / cities
Los Angeles, California • Atlanta, Georgia • Clemson, South Carolina + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 26, 2022 · Synced Oct 15, 2026, 1:21 AM EDT
Completed No phase listed Observational

Functional and Lymphocytic Markers of Respiratory Morbidity in Hyperoxic Preemies

NCT01607216
View directory record Official record
Conditions
Prematurity, Symptomatic Respiratory Disease, Bronchopulmonary Dysplasia
Interventions
Not listed
Lead sponsor
University of Rochester
Other
Eligibility
Up to 7 Days
Enrollment
277 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
2
States / cities
Buffalo, New York • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jan 13, 2020 · Synced Oct 15, 2026, 1:21 AM EDT
Completed Not applicable Interventional

Late Permissive Hypercapnia for Intubated and Ventilated Preterm Infants

NCT02799875
View directory record Official record
Conditions
Premature Neonate
Interventions
Higher permissive hypercapnia, Lower Permissive Hypercapnia
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
7 Days to 14 Days
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 3, 2021 · Synced Oct 15, 2026, 1:21 AM EDT
Recruiting Not applicable Interventional

Manual T-piece Versus Ventilator Positive Pressure Ventilation During Resuscitation of Extremely Premature Neonates

NCT06849596
View directory record Official record
Conditions
Neonatal Resuscitation, Apnea Neonatal
Interventions
Ventilator derived positive pressure ventilation - V-PPV, T-piece resuscitator (TPR)
Device
Lead sponsor
Michelle Baczynski
Other
Eligibility
25 Weeks to 29 Weeks
Enrollment
780 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 9, 2026 · Synced Oct 15, 2026, 1:21 AM EDT
Not yet recruiting Not applicable Interventional

Pivotal Study to Assess Safety and Performance of Neola®, a Novel Lung Monitoring Device for Neonates

NCT07060911
View directory record Official record
Conditions
RDS of Prematurity, Preterm Birth, Lung Diseases
Interventions
Lung monitoring with the Neola device
Device
Lead sponsor
Neola Medical Inc
Industry
Eligibility
1 Day to 44 Weeks
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Palo Alto, California • Camden, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 11, 2025 · Synced Oct 15, 2026, 1:21 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparing IM vs. Vaginal Progesterone for Pre-term Birth

NCT00579553
View directory record Official record
Conditions
Infant, Premature, Premature Birth
Interventions
Intramuscular Progesterone, Vaginal Progesterone
Drug
Lead sponsor
University of Oklahoma
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
174 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated May 19, 2021 · Synced Oct 15, 2026, 1:21 AM EDT
Not listed Not applicable Interventional

Growth and Nutritional Status of Very Low Birth Weight Infants Fed a High Protein Exclusive Human Milk Diet

NCT03839173
View directory record Official record
Conditions
Premature Infant, Breast Milk Expression
Interventions
Human milk based human milk fortifier
Other
Lead sponsor
Augusta University
Other
Eligibility
23 Weeks to 33 Weeks
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Jul 29, 2019 · Synced Oct 15, 2026, 1:21 AM EDT
Completed Phase 4 Interventional Results available

Pediatric Study to Evaluate Risk of Developing Essential Fatty Acid Deficiency When Receiving Clinolipid or Standard-of-Care Lipid Emulsion (Part A)

NCT04555044
View directory record Official record
Conditions
Essential Fatty Acid Deficiency (EFAD)
Interventions
Clinolipid, Intralipid
Drug
Lead sponsor
Baxter Healthcare Corporation
Industry
Eligibility
0 Years to 17 Years
Enrollment
101 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
9
States / cities
Mobile, Alabama • New Haven, Connecticut • Orlando, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Dec 27, 2023 · Synced Oct 15, 2026, 1:21 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Little Lungs Study

NCT06855043
View directory record Official record
Conditions
Invasive Mechanical Ventilation, Severe Respiratory Distress Syndrome
Interventions
Calfactant, Budesonide
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
7 Days to 14 Days
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Sep 29, 2026 · Synced Oct 15, 2026, 1:21 AM EDT
Completed No phase listed Observational

Impact of Respiratory Pathogens in Infants

NCT01789268
View directory record Official record
Conditions
Respiratory Tract Infection
Interventions
Respiratory Inductive Plethysmography
Device
Lead sponsor
University of Rochester
Other
Eligibility
0 Days to 3 Years
Enrollment
267 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2019
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Mar 2, 2022 · Synced Oct 15, 2026, 1:21 AM EDT
Not listed Not applicable Interventional

Bilateral Infant Stimulation Study

NCT06353243
View directory record Official record
Conditions
Parent-Child Relations, Preterm Birth, Stress Reaction, Hospitalism in Children
Interventions
Bilateral alternating stimulation
Behavioral
Lead sponsor
Oregon Health and Science University
Other
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated May 3, 2024 · Synced Oct 15, 2026, 1:21 AM EDT
Recruiting Not applicable Interventional

A Randomized Controlled Trial of Impact of Wearable, Wireless Breast Pumps on Frequency and Efficacy of Milk Expression in Mothers of Premature Infants

NCT06723067
View directory record Official record
Conditions
Premature Birth
Interventions
Wearable wireless breast pump
Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Dec 9, 2024 · Synced Oct 15, 2026, 1:21 AM EDT
Completed Phase 3 Interventional

Glutamine Supplementation to Prevent Death or Infection in Extremely Premature Infants

NCT00005775
View directory record Official record
Conditions
Infant, Newborn, Infant, Low Birth Weight, Infant, Small for Gestational Age, Infant, Premature, Sepsis
Interventions
Glutamine, Placebo
Drug
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 72 Hours
Enrollment
1,433 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2001
U.S. locations
15
States / cities
Birmingham, Alabama • Palo Alto, California • San Diego, California + 12 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2015 · Synced Oct 15, 2026, 1:21 AM EDT
Completed Not applicable Interventional

Delayed Cord Clamping in Preterm Neonates

NCT02478684
View directory record Official record
Conditions
Premature Birth of Newborn, Infant, Very Low Birth Weight, Delayed Separation of Umbilical Cord, Placental Transfusion
Interventions
30 Seconds of placental blood transfusion, 60 Seconds of placental blood transfusion
Other
Lead sponsor
Weill Medical College of Cornell University
Other
Eligibility
28 Weeks to 35 Weeks
Enrollment
105 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 30, 2019 · Synced Oct 15, 2026, 1:21 AM EDT
Completed No phase listed Observational

Improving Prematurity-Related Respiratory Outcomes at Vanderbilt

NCT01460576
View directory record Official record
Conditions
Preterm Birth, Bronchopulmonary Dysplasia, Chronic Lung Disease of Prematurity
Interventions
Not listed
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
Up to 7 Days
Enrollment
253 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
2
States / cities
Jackson, Tennessee • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated May 5, 2017 · Synced Oct 15, 2026, 1:21 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Development of a Therapeutic Device to Improve Speech Sound Differentiation in Preterm Infants

NCT06063122
View directory record Official record
Conditions
Premature Birth
Interventions
smallTalk NICU Active
Device
Lead sponsor
Thrive Neuromedical, LLC
Industry
Eligibility
32 Weeks to 35 Weeks
Enrollment
203 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
2
States / cities
Atlanta, Georgia • Chagrin Falls, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Oct 15, 2026, 1:21 AM EDT
Completed No phase listed Observational Results available

Comparative Effectiveness of Treatment Options for Genital Herpes Infection to Reduce Adverse Pregnancy Outcomes

NCT02986802
View directory record Official record
Conditions
HSV-2 Infection, PreTerm Birth, Pregnancy Complications
Interventions
Not listed
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older · Female only
Enrollment
89,132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Oakland, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2021 · Synced Oct 15, 2026, 1:21 AM EDT
Completed No phase listed Observational

Stochastic Resonance Mattress (Physiological Interventions) and Biomarkers for Enhancing Neonatal Health

NCT01643057
View directory record Official record
Conditions
Apnea of Prematurity
Interventions
Stochastic Resonance Mattress
Device
Lead sponsor
Wyss Institute at Harvard University
Other
Eligibility
Not listed
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 10, 2015 · Synced Oct 15, 2026, 1:21 AM EDT