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ClinicalTrials.gov public records Last synced Oct 15, 2026, 2:05 AM EDT

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Showing 385–408 of 634 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Complications of Prematurity Clear all
Completed No phase listed Observational Accepts healthy volunteers

Infant Immune Response to Bacterial Infection

NCT00546195
View directory record Official record
Conditions
Prematurity, Histologic Chorioamnionitis
Interventions
Not listed
Lead sponsor
Eunice Kennedy Shriver National Institute of Child Health and Human Development (NICHD)
NIH
Eligibility
Not listed
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 15, 2026, 2:05 AM EDT
Completed No phase listed Observational

A Multicenter Assessment of a Spontaneous Preterm Birth Risk Predictor

NCT02787213
View directory record Official record
Conditions
Preterm Birth
Interventions
Not listed
Lead sponsor
Sera Prognostics, Inc.
Industry
Eligibility
18 Years to 55 Years · Female only
Enrollment
5,011 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
18
States / cities
Phoenix, Arizona • Orange, California • San Diego, California + 15 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2021 · Synced Oct 15, 2026, 2:05 AM EDT
Suspended Not applicable Interventional

The Milk, Growth and Microbiota Study

NCT03220282
View directory record Official record
Conditions
Preterm Infant, Growth Delay, Microbial Colonization, Breastfeeding, Breast Milk Substitute Intolerance
Interventions
Donor milk, Preterm infant formula
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
1 Hour to 96 Hours
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 18, 2026 · Synced Oct 15, 2026, 2:05 AM EDT
Active, not recruiting No phase listed Observational

Cincinnati Infant Neurodevelopment Early Prediction Study (CINEPS)

NCT03345069
View directory record Official record
Conditions
Premature Infant
Interventions
Not listed
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Up to 3 Years
Enrollment
393 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 7, 2024 · Synced Oct 15, 2026, 2:05 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Nanovectors to Prevent Placental Passage of Tocolytic Agents

NCT02199756
View directory record Official record
Conditions
Preterm Labor
Interventions
Not listed
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years to 49 Years · Female only
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 2, 2018 · Synced Oct 15, 2026, 2:05 AM EDT
Active, not recruiting Not applicable Interventional Results available

Early Protein Supplementation in Extremely Preterm Infants Fed Human Milk

NCT04325308
View directory record Official record
Conditions
Prematurity; Extreme, Feeding Disorder Neonatal, Breast Milk Expression, Growth Failure, Microbial Colonization
Interventions
Protein-enriched human milk diet, Usual human milk diet
Procedure
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
1 Day to 4 Days
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 15, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Donor Human Milk and Neurodevelopmental Outcomes in Very Low Birthweight (VLBW) Infants

NCT01232725
View directory record Official record
Conditions
Neurodevelopmental Outcomes of VLBW Infants
Interventions
Donor Human Milk
Dietary Supplement
Lead sponsor
Tarah T Colaizy
Other
Eligibility
Up to 24 Months
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Aug 4, 2017 · Synced Oct 15, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Effect of Vitamin D in Diets of Preterm Infants

NCT01698840
View directory record Official record
Conditions
Premature Infants
Interventions
Vitamin D, Placebo
Dietary Supplement
Lead sponsor
Baylor College of Medicine
Other
Eligibility
Not listed
Enrollment
39 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 29, 2026 · Synced Oct 15, 2026, 2:05 AM EDT
Completed Phase 4 Interventional

Safety of Manganese Restriction in Neonatal Parenteral Nutrition

NCT04259008
View directory record Official record
Conditions
Infant, Newborn, Disease
Interventions
Manganese omission, 5 mCg/kg/day manganese from "Multitrace-4 Neonatal."
Other
Lead sponsor
Sharp HealthCare
Other
Eligibility
Up to 1 Day
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Aug 25, 2021 · Synced Oct 15, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nourishing Beginnings: Addressing Food Insecurity During Pregnancy

NCT05341960
View directory record Official record
Conditions
Pregnancy Related, Food Insecurity, Premature Birth, Pregnancy Complications
Interventions
Food Delivery, Financial Support
Behavioral · Other
Lead sponsor
Case Western Reserve University
Other
Eligibility
18 Years and older · Female only
Enrollment
162 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
2
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 15, 2026, 2:05 AM EDT
Completed Phase 3 Interventional

Obstetrics and Periodontal Therapy (OPT) Study

NCT00066131
View directory record Official record
Conditions
Periodontitis, Infant, Premature
Interventions
Periodontal scaling and root planing, Scaling and root planing
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
16 Years and older · Female only
Enrollment
823 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 27, 2015 · Synced Oct 15, 2026, 2:05 AM EDT
Withdrawn Phase 2 Interventional

Inhaled PGE1 in Neonatal Hypoxemic Respiratory Failure

NCT00598429
View directory record Official record
Conditions
Infant, Newborn, Respiratory Insufficiency, Pulmonary Hypertension, Respiratory Distress Syndrome, Newborn, Streptococcal Infections
Interventions
Inhaled Prostaglandin E1
Drug
Lead sponsor
NICHD Neonatal Research Network
Network
Eligibility
Up to 7 Days
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008
U.S. locations
11
States / cities
Birmingham, Alabama • Palo Alto, California • Iowa City, Iowa + 7 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2019 · Synced Oct 15, 2026, 2:05 AM EDT
Not listed Not applicable Interventional

Does Timing Matter? Supporting Play, Exploration, and Early Developmental Intervention

NCT03518736
View directory record Official record
Conditions
Preterm Infant, Cerebral Palsy
Interventions
Supporting Play Exploration and Developmental Intervention (SPEEDI)
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
Up to 6 Months
Enrollment
85 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2025
U.S. locations
2
States / cities
Los Angeles, California • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced Oct 15, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Educational/Behavioral Intervention Program for Parents of Premature Infants

NCT00120614
View directory record Official record
Conditions
Premature Birth
Interventions
Premature infant behavior and development information, Parental activities to support premature infant information
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
260 participants
Timeline
2001 – 2007
U.S. locations
2
States / cities
Rochester, New York • Syracuse, New York
Source: ClinicalTrials.gov public record
Updated Apr 8, 2009 · Synced Oct 15, 2026, 2:05 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Trial of Progesterone in Twins and Triplets to Prevent Preterm Birth (STTARS)

NCT00099164
View directory record Official record
Conditions
Preterm Birth, Pregnancy, Multifetal
Interventions
17 alpha-hydroxyprogesterone caproate (17P)
Drug
Lead sponsor
The George Washington University Biostatistics Center
Other
Eligibility
Female only
Enrollment
795 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
14
States / cities
Birmingham, Alabama • Chicago, Illinois • Detroit, Michigan + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 21, 2019 · Synced Oct 15, 2026, 2:05 AM EDT
Completed Not applicable Interventional

Ambulation for Latency During Expectant Management of PPROM

NCT04230967
View directory record Official record
Conditions
Preterm Premature Rupture of the Membranes, Pregnancy Complications, Pregnancy, High Risk
Interventions
Ambulation Group, Routine Care
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
12 Years to 55 Years · Female only
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 28, 2023 · Synced Oct 15, 2026, 2:05 AM EDT
Terminated Phase 3 Interventional Results available

A Phase III Efficacy and Safety Study of Intravenous Retosiban Versus Placebo for Women in Spontaneous Preterm Labor

NCT02377466
View directory record Official record
Conditions
Obstetric Labour, Premature
Interventions
Retosiban IV infusion, Placebo IV infusion
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
12 Years to 45 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
33
States / cities
Birmingham, Alabama • Mobile, Alabama • Tucson, Arizona + 29 more
Source: ClinicalTrials.gov public record
Updated Jul 28, 2020 · Synced Oct 15, 2026, 2:05 AM EDT
Recruiting Phase 2Phase 3 Interventional Accepts healthy volunteers

Limited Versus Extended Trophic Feeding (LET-FEED) Trial

NCT06893939
View directory record Official record
Conditions
Sepsis, Length of Stay, Mortality, Neurodevelopmental Delay
Interventions
Limited Trophic Feeds (1 day of trophic feeds), Extended Trophic Feeds (3 days of trophics)
Other
Lead sponsor
University of Washington
Other
Eligibility
0 Years to 2 Years
Enrollment
350 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
6
States / cities
Birmingham, Alabama • Tampa, Florida • Oklahoma City, Oklahoma + 3 more
Source: ClinicalTrials.gov public record
Updated Aug 17, 2026 · Synced Oct 15, 2026, 2:05 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

DE-RESTRICT: Deimplementing Activity Restriction for Preterm Birth Prevention

NCT07698483
View directory record Official record
Conditions
Preterm Birth, Activity Restriction, Bed Rest, Low-Value Care
Interventions
Multicomponent deimplementation strategy
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
237 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
2
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Oct 15, 2026, 2:05 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Placental and Cord Blood Markers Associated With Premature Birth and Disorders of Premature Birth in Newborn Infants

NCT01439048
View directory record Official record
Conditions
Premature Birth
Interventions
Not listed
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
1 Minute to 3 Months
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2015
U.S. locations
1
States / cities
Wauwatosa, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 28, 2015 · Synced Oct 15, 2026, 2:05 AM EDT
Completed Phase 3 Interventional

Beneficial Effects of Antenatal Magnesium Sulfate (BEAM Trial)

NCT00014989
View directory record Official record
Conditions
Cerebral Palsy, Intraventricular Hemorrhage, Periventricular Leukomalacia, Pulmonary Edema, Abruptio Placentae
Interventions
magnesium sulfate
Drug
Lead sponsor
The George Washington University Biostatistics Center
Other
Eligibility
Female only
Enrollment
2,136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2007
U.S. locations
17
States / cities
Birmingham, Alabama • Miami, Florida • Chicago, Illinois + 14 more
Source: ClinicalTrials.gov public record
Updated Jul 12, 2019 · Synced Oct 15, 2026, 2:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Improving Parental Knowledge: Supplementation of Prematurity Counseling With Written Information

NCT01418950
View directory record Official record
Conditions
Premature Birth
Interventions
Written information and verbal counseling
Other
Lead sponsor
Medical College of Wisconsin
Other
Eligibility
18 Years and older · Female only
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2012
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Dec 18, 2013 · Synced Oct 15, 2026, 2:05 AM EDT
Completed Phase 1 Interventional

Pravastatin for Prevention of Preeclampsia

NCT01717586
View directory record Official record
Conditions
Preeclampsia
Interventions
Pravastatin, Placebo
Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years and older · Female only
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2024
U.S. locations
3
States / cities
Chicago, Illinois • Pittsburgh, Pennsylvania • Galveston, Texas
Source: ClinicalTrials.gov public record
Updated May 4, 2025 · Synced Oct 15, 2026, 2:05 AM EDT
Terminated Phase 4 Interventional

Removal Versus Retention of Cerclage in Preterm Premature Rupture of Membranes (PPROM)

NCT00201656
View directory record Official record
Conditions
Fetal Membranes, Premature Rupture
Interventions
Retention of Cerclage, Removal of Cerclage, Removal vs. Retention of Cervical Cerclage
Procedure
Lead sponsor
Obstetrix Medical Group
Industry
Eligibility
18 Years to 60 Years · Female only
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2014
U.S. locations
23
States / cities
Mesa, Arizona • Phoenix, Arizona • Tucson, Arizona + 18 more
Source: ClinicalTrials.gov public record
Updated Dec 19, 2014 · Synced Oct 15, 2026, 2:05 AM EDT