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Showing 1–24 of 66 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Compression; Vein Clear all
Completed Early Phase 1 Interventional Accepts healthy volunteers

Evaluation of the OsciPulse Rapid Cycling Compression Device Effects on Venous Blood Flow

NCT05087108
View directory record Official record
Conditions
Venous Thromboses, Venous Stasis
Interventions
OsciPulse system, Reference Therapy 1, Refence Therapy 2
Device
Lead sponsor
OsciFlex LLC
Industry
Eligibility
40 Years to 90 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 8, 2023 · Synced Jun 10, 2026, 10:25 AM EDT
Withdrawn Not applicable Interventional

A Clinical Study to Assess a Compression Device in Patients With Venous Leg Ulcers

NCT02561013
View directory record Official record
Conditions
Varicose Ulcer
Interventions
3M™ Coban™ Custom Fit Compression System, Profore
Device
Lead sponsor
3M
Industry
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
3
States / cities
Montgomery, Alabama • Saint Paul, Minnesota • Toledo, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 24, 2015 · Synced Jun 10, 2026, 10:25 AM EDT
Completed Not applicable Interventional Results available

Comparison of Percutaneous Closure to Manual Compression for Hemostasis

NCT04180540
View directory record Official record
Conditions
Atrial Fibrillation
Interventions
Percutaneous Closure, Manual Compression
Device · Other
Lead sponsor
Michael S. Lloyd
Other
Eligibility
18 Years and older
Enrollment
109 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Feb 6, 2022 · Synced Jun 10, 2026, 10:25 AM EDT
Completed Not applicable Interventional Results available

Intermittent Pneumatic Compression Device for Vein Dilation in Kidney Disease Patients to Enable AVF Creation (FACT)

NCT04063787
View directory record Official record
Conditions
Kidney Diseases
Interventions
Fist Assist
Device
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 11, 2023 · Synced Jun 10, 2026, 10:25 AM EDT
Withdrawn Not applicable Interventional

Post Thrombotic Syndrome Prevention Study

NCT03039517
View directory record Official record
Conditions
Post Thrombotic Syndrome, Deep Vein Thrombosis
Interventions
ACTitouch, Compression garments (stockings)
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 21, 2019 · Synced Jun 10, 2026, 10:25 AM EDT
Recruiting Not applicable Interventional

The ROle of Compression StocKings in Heart Failure Patients

NCT06350695
View directory record Official record
Conditions
Heart Failure，Congestive, Leg Edema, Venous Insufficiency, Venous Ulcers
Interventions
low grade compression stockings (10-15 mmHg), high grade compression stockings (20-30 mmHg)
Device
Lead sponsor
University of Maryland, Baltimore
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 1, 2024 · Synced Jun 10, 2026, 10:25 AM EDT
Completed Not applicable Interventional

Intermittent Pneumatic Compression of the Thigh

NCT05659394
View directory record Official record
Conditions
Venous Leg Ulcer
Interventions
Standard Wound Care Alone, Stand Wound Care plus IPC
Other · Device
Lead sponsor
Huntleigh Healthcare Ltd
Industry
Eligibility
Not listed
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
5
States / cities
Hollywood, Florida • North Port, Florida • Tulsa, Oklahoma + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 16, 2024 · Synced Jun 10, 2026, 10:25 AM EDT
Withdrawn Not applicable Interventional

Evaluation of Cirvo™ Mobile Compression Device for Treatment of Venous Leg Ulcers

NCT03544788
View directory record Official record
Conditions
Venous Leg Ulcer
Interventions
Cirvo™ Therapy
Device
Lead sponsor
Radial Medical, Inc.
Industry
Eligibility
18 Years to 80 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2019 · Synced Jun 10, 2026, 10:25 AM EDT
Withdrawn Not applicable Interventional

Compliance of Compression Therapy in Healed Venous Ulcerations

NCT01680809
View directory record Official record
Conditions
Venous Insufficiency
Interventions
Compression stocking 15-20mmHg, Compression stocking 20-30mmHg
Device
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Richmond Heights, Ohio
Source: ClinicalTrials.gov public record
Updated May 16, 2022 · Synced Jun 10, 2026, 10:25 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Internal Jugular Vein Compression Collar for Novel Symptomatic Treatment of Venous Pulsatile Tinnitus

NCT05441540
View directory record Official record
Conditions
Pulsatile Tinnitus
Interventions
Internal Jugular Vein Compression Collar
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Apr 15, 2024 · Synced Jun 10, 2026, 10:25 AM EDT
Completed Not applicable Interventional Results available

The Effect of Inelastic Compression System on Quality of Life in People With Chronic Venous Insufficiency

NCT05051540
View directory record Official record
Conditions
Chronic Venous Insufficiency
Interventions
Sigvaris Compreflex Inelastic Compression Wrap
Device
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Jun 10, 2026, 10:25 AM EDT
Completed No phase listed Observational

Venogram vs. Intravascular Ultrasound (IVUS) for Diagnosing Iliac Vein Obstruction

NCT02142062
View directory record Official record
Conditions
Iliac Venous Compression
Interventions
Not listed
Lead sponsor
Volcano Corporation
Industry
Eligibility
18 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
11
States / cities
Birmingham, Alabama • Phoenix, Arizona • Bridgeport, Connecticut + 8 more
Source: ClinicalTrials.gov public record
Updated Aug 10, 2016 · Synced Jun 10, 2026, 10:25 AM EDT
Completed Not applicable Interventional

Evaluation of Bilayered Cellular Matrix (OrCel) for the Treatment of Venous Ulcers

NCT00270946
View directory record Official record
Conditions
Venous Leg Ulcer, Venous Stasis Ulcer
Interventions
Bilayered Cellular Matrix (OrCel)
Device
Lead sponsor
Ortec International
Industry
Eligibility
18 Years to 85 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
1
States / cities
Montgomery, Alabama
Source: ClinicalTrials.gov public record
Updated Dec 28, 2005 · Synced Jun 10, 2026, 10:25 AM EDT
Terminated Not applicable Interventional Results available

ActiV.A.C.+ Compression Therapy Versus Compression Therapy Alone for the Treatment of Chronic Venous Ulcerations

NCT01528293
View directory record Official record
Conditions
Chronic Venous Hypertension With Ulcer
Interventions
ActiVAC System, Compression therapy
Device · Other
Lead sponsor
Georgetown University
Other
Eligibility
18 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Mar 18, 2020 · Synced Jun 10, 2026, 10:25 AM EDT
Enrolling by invitation Not applicable Interventional

Percutaneous Closure Versus Figure-of-eight Suture for Hemostasis in Leadless Pacemaker Implantation.

NCT06837870
View directory record Official record
Conditions
Vascular Closure, Pacemaker Implantation, Leadless Pacemaker
Interventions
percutaneous suture mediated closure, Figure of Eight Suture
Device
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Jun 10, 2026, 10:25 AM EDT
Terminated Phase 4 Interventional Results available

Flexitouch Compression System for Venous Stasis Ulcer

NCT00534937
View directory record Official record
Conditions
Venous Stasis Ulcer
Interventions
Compression wrapping, Flexitouch compression pump
Procedure
Lead sponsor
West Penn Allegheny Health System
Other
Eligibility
18 Years to 90 Years
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
2
States / cities
Cleveland, Ohio • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 28, 2013 · Synced Jun 10, 2026, 10:25 AM EDT
Not listed Not applicable Interventional

Standard Compression Therapy With/Without Application of Skin Allograft (Theraskin) for Venous Leg Ulcer Treatment

NCT03935386
View directory record Official record
Conditions
Chronic Venous Hypertension With Ulcer
Interventions
Standard Multi-layered Compression dressing, Standard Multi-layered Compression dressing with a cryopreserved skin allograft (TheraSkin)
Procedure
Lead sponsor
Solsys Medical LLC
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2020
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated May 1, 2019 · Synced Jun 10, 2026, 10:25 AM EDT
Completed Not applicable Interventional

Game-Based Foot & Ankle Exercise for Those With Lower Extremity Edema

NCT05520008
View directory record Official record
Conditions
Lower Extremity Swelling, Lower Extremity Edema, Venous Insufficiency of Leg
Interventions
Game-based exercise
Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Jun 10, 2026, 10:25 AM EDT
Completed Phase 3 Interventional Results available

Study Investigating the Safety and Efficacy of HP802-247 in the Treatment of Venous Leg Ulcers

NCT01656889
View directory record Official record
Conditions
Venous Leg Ulcers
Interventions
HP-802-247, Vehicle
Biological
Lead sponsor
Healthpoint
Industry
Eligibility
18 Years and older
Enrollment
447 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
45
States / cities
Glendale, Arizona • Phoenix, Arizona • Tucson, Arizona + 37 more
Source: ClinicalTrials.gov public record
Updated Mar 13, 2016 · Synced Jun 10, 2026, 10:25 AM EDT
Not listed Phase 4 Interventional

Compression Aided Management of Edema in Patients With C3 Venous Disease

NCT00766974
View directory record Official record
Conditions
Chronic Venous Disease
Interventions
Anti-embolism Knee High Stocking, 20-30 Knee High Compression Stocking
Device
Lead sponsor
BSN Medical Inc
Industry
Eligibility
18 Years to 80 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
West Roxbury, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 5, 2008 · Synced Jun 10, 2026, 10:25 AM EDT
Enrolling by invitation Phase 1Phase 2 Interventional

Evaluation of Lymphatic Response to Physiotherapy in Patients With Swelling Associated With Superficial Venous Disease

NCT07165340
View directory record Official record
Conditions
Chronic Venous Disease
Interventions
Indocyanine Green near infrared fluorescence imaging, advanced pneumatic compression, Duplex ultrasound, compression wrap
Combination Product · Device · Diagnostic Test
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 15, 2025 · Synced Jun 10, 2026, 10:25 AM EDT
Recruiting No phase listed Observational

Abbott Vascular Medical Device Registry

NCT04573660
View directory record Official record
Conditions
Acute Myocardial Infarction, Restenoses, Coronary, Coronary Artery Lesions, Venous Embolism, Arterial Embolism
Interventions
Coronary and peripheral stents, Pacing catheters, Vascular plugs, Measurement and imaging (FFR and OCT), Peripheral dilatation catheters, Coronary dilatation catheters, Coronary and peripheral guidewires, Vessel closure/compression devices, Vascular access introducers
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
3,784 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2031
U.S. locations
7
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 4 more
Source: ClinicalTrials.gov public record
Updated Jul 2, 2025 · Synced Jun 10, 2026, 10:25 AM EDT
Completed Not applicable Interventional

Preventing the Development of Venous Insufficiency in Pregnant Women Through Use of Compression Stockings

NCT01793194
View directory record Official record
Conditions
Venous Insufficiency
Interventions
Compression Stockings
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 28, 2018 · Synced Jun 10, 2026, 10:25 AM EDT
Completed Phase 3 Interventional Results available

The SOX Trial: Compression Stockings to Prevent the Post-Thrombotic Syndrome

NCT00143598
View directory record Official record
Conditions
Deep Venous Thrombosis
Interventions
Knee-length, graduated elastic compression stocking, Knee-length, placebo stocking
Device
Lead sponsor
Sir Mortimer B. Davis - Jewish General Hospital
Other
Eligibility
18 Years and older
Enrollment
806 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2012
U.S. locations
3
States / cities
Detroit, Michigan • Durham, North Carolina • Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Aug 17, 2014 · Synced Jun 10, 2026, 10:25 AM EDT