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ClinicalTrials.gov public records Last synced Oct 22, 2026, 5:33 AM EDT

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Showing 217–240 of 366 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Compulsive Personality Disorder Clear all
Completed No phase listed Observational Accepts healthy volunteers

Neural Correlates of Compulsivity

NCT05195476
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Not listed
Lead sponsor
Columbia University
Other
Eligibility
18 Years to 50 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 6, 2024 · Synced Oct 22, 2026, 5:33 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Pediatric Acute-Onset Neuropsychiatric Syndrome (PANS)

NCT03507218
View directory record Official record
Conditions
Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
3 Years and older
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
8
States / cities
Tucson, Arizona • Stanford, California • Wilmington, Delaware + 5 more
Source: ClinicalTrials.gov public record
Updated Oct 25, 2019 · Synced Oct 22, 2026, 5:33 AM EDT
Recruiting No phase listed Observational

University of Iowa Interventional Psychiatry Service Patient Registry

NCT04480918
View directory record Official record
Conditions
Treatment Resistant Depression, Major Depressive Episode, Major Depression, Major Depressive Disorder, Bipolar Disorder, Bipolar Depression, Obsessive-Compulsive Disorder
Interventions
Electroconvulsive Therapy (ECT), Transcranial Magnetic Stimulation (TMS), Ketamine, Esketamine, Deep Transcranial Magnetic Stimulation (dTMS)
Device · Drug
Lead sponsor
Mark Niciu
Other
Eligibility
18 Years to 99 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2050
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Oct 22, 2026, 5:33 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

I-123 Brain Studies of Serotonin Metabolism in Psychiatric Patients and Normal Volunteers

NCT00001771
View directory record Official record
Conditions
Healthy, Mental Disorder, Obsessive Compulsive Disorder, Schizophrenia, Tourette Syndrome
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1998 – 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 22, 2026, 5:33 AM EDT
Completed Not applicable Interventional

Attaining and Maintaining Wellness in Obsessive-compulsive Disorder

NCT01686087
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Monthly Booster Sessions of EX/RP, Visits with MD and independent evaluators
Behavioral · Procedure
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 75 Years
Enrollment
137 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
New York, New York • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 16, 2026 · Synced Oct 22, 2026, 5:33 AM EDT
Completed Not applicable Interventional

Functional and Cognitive Rehabilitation of Hoarding Disorder

NCT04697849
View directory record Official record
Conditions
Hoarding Disorder
Interventions
Cognitive Rehabilitation and Exposure/Sorting Therapy, Case Management
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Dec 10, 2025 · Synced Oct 22, 2026, 5:33 AM EDT
Terminated Phase 2 Interventional

Study of NPL-2003 in Adolescents With Obsessive Compulsive Disorder (OCD)

NCT00515255
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Minocycline
Drug
Lead sponsor
Neuropharm
Industry
Eligibility
12 Years to 17 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
2
States / cities
New York, New York • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 27, 2012 · Synced Oct 22, 2026, 5:33 AM EDT
Completed No phase listed Observational

Genetics of Obsessive-Compulsive Disorder

NCT00001548
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
18 Years and older
Enrollment
1,067 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1996 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 6, 2017 · Synced Oct 22, 2026, 5:33 AM EDT
Completed Phase 2 Interventional Results available

Marinol in Trichotillomania or Obsessive Compulsive Disorder

NCT01093976
View directory record Official record
Conditions
Trichotillomania, Obsessive Compulsive Disorder
Interventions
Dronabinol
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 65 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 23, 2023 · Synced Oct 22, 2026, 5:33 AM EDT
Enrolling by invitation No phase listed Observational

Assess the Utility of a Speech-based Machine Learning Algorithm to Predict Treatment Response to Psychiatric Interventions

NCT06823024
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD), Bipolar Disorders, Major Depressive Disorder, Post-Traumatic Stress Disorder, PTSD, Generalized Anxiety Disorder (GAD)
Interventions
Not listed
Lead sponsor
Psyrin Inc.
Industry
Eligibility
18 Years to 68 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
2
States / cities
Sunnyvale, California • New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 18, 2025 · Synced Oct 22, 2026, 5:33 AM EDT
Active, not recruiting Not applicable Interventional

Identifying Networks Underlying Compulsivity in Anorexia Nervosa for Targeting With Neuromodulation

NCT06138782
View directory record Official record
Conditions
Anorexia Nervosa
Interventions
Repetitive Transcranial Magnetic Stimulation (rTMS)
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
16 Years to 75 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated May 1, 2026 · Synced Oct 22, 2026, 5:33 AM EDT
Completed Early Phase 1 Interventional

Cognitive Remediation for Neuropsychological Impairment in Compulsive Hoarding

NCT01451697
View directory record Official record
Conditions
Hoarding Disorder, Attentional Impairment
Interventions
Cognitive Remediation, Control (Placebo)
Behavioral
Lead sponsor
Hartford Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated May 20, 2019 · Synced Oct 22, 2026, 5:33 AM EDT
Not listed Phase 4 Interventional

A Study to Evaluate the Benefit of Octagam 5%® in Subjects With Pediatric Acute-onset Neuropsychiatric Syndrome (PANS)

NCT03348618
View directory record Official record
Conditions
Pediatric Acute-Onset Neuropsychiatric Syndrome, Pediatric Autoimmune Neuropsychiatric Disorders Associated With Streptococcal Infections
Interventions
IVIG
Biological
Lead sponsor
IMMUNOe Research Centers
Industry
Eligibility
4 Years to 16 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
3
States / cities
Centennial, Colorado • Papillion, Nebraska • Charlotte, North Carolina
Source: ClinicalTrials.gov public record
Updated Nov 19, 2019 · Synced Oct 22, 2026, 5:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cognitive Rehab and Exposure Treatment for Hoarding

NCT02402647
View directory record Official record
Conditions
Hoarding Disorder
Interventions
Cognitive Rehabilitation and Exposure/Sorting Treatment (CREST), Exposure Therapy (ET)
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 85 Years
Enrollment
115 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2023
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Oct 22, 2026, 5:33 AM EDT
Recruiting Not applicable Interventional

SEEG-Guided DBS for OCD

NCT05623306
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Stereoencephalography (SEEG), Deep Brain Stimulation (DBS)
Device
Lead sponsor
Casey H. Halpern, M.D.
Other
Eligibility
22 Years to 75 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2030
U.S. locations
2
States / cities
Stanford, California • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Oct 22, 2026, 5:33 AM EDT
Completed Phase 4 Interventional

Treatment of Obsessive-Compulsive Disorder

NCT00000373
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
olanzapine + fluoxetine, placebo + fluoxetine
Drug
Lead sponsor
University of Florida
Other
Eligibility
14 Years to 70 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1992 – 2003
U.S. locations
2
States / cities
Gainesville, Florida • Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 27, 2013 · Synced Oct 22, 2026, 5:33 AM EDT
Recruiting No phase listed Observational

Retrospective Analyses of TrakStar Database

NCT06917339
View directory record Official record
Conditions
Depression, Obsessive-Compulsive Disorder, Anxiety Depression
Interventions
NeuroStar Advanced TMS Therapy System
Device
Lead sponsor
Neuronetics
Other
Eligibility
5 Years to 120 Years
Enrollment
156,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2035
U.S. locations
1
States / cities
Malvern, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 9, 2026 · Synced Oct 22, 2026, 5:33 AM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Sensory Gating Measured With Microelectrode Recording (MER) During Deep Brain Stimulation (DBS) Surgery

NCT02320266
View directory record Official record
Conditions
Parkinson's Disease, Essential Tremor, Dystonia, Obsessive Compulsive Disorder
Interventions
Not listed
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 80 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Oct 22, 2026, 5:33 AM EDT
Recruiting Phase 1Phase 2 Interventional

Pilot Study of RR-HNK in OCD

NCT06575075
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
RR-HNK/Hydroxynorketamine, Placebo
Drug
Lead sponsor
Carolyn Rodriguez
Other
Eligibility
18 Years to 65 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 12, 2026 · Synced Oct 22, 2026, 5:33 AM EDT
Completed Phase 2 Interventional Results available

Double-Blind Lamictal (Lamotrigine) in Neurotic Excoriation

NCT00513019
View directory record Official record
Conditions
Neurotic Excoriation, Pathologic Skin Picking, Psychogenic Excoriation, Dermatillomania
Interventions
Lamictal (lamotrigine), Placebo
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 65 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 23, 2023 · Synced Oct 22, 2026, 5:33 AM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Cognitive Rehabilitation and Exposure Therapy for Geriatric Hoarding

NCT05254015
View directory record Official record
Conditions
Hoarding Disorder, Obsessive-Compulsive Disorder
Interventions
Cognitive Rehabilitation and Exposure/Sorting Therapy (CREST), Case Management
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
50 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Apr 6, 2023 · Synced Oct 22, 2026, 5:33 AM EDT
Completed Not applicable Interventional

CBT for Pediatric OCD: Community Training Pilot

NCT02202915
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Behavioral Checklist
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
5 Years to 17 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
East Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jul 12, 2019 · Synced Oct 22, 2026, 5:33 AM EDT
Active, not recruiting Phase 1 Interventional

Effects of Repeated Psilocybin Dosing in OCD

NCT05370911
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Psilocybin
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
2
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 4, 2026 · Synced Oct 22, 2026, 5:33 AM EDT
Recruiting Not applicable Interventional

ERP to Improve Functioning in Veterans With OCD

NCT05240924
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD), Comorbid Post-Traumatic Stress Disorder and OCD
Interventions
Exposure and Response Prevention, Stress Management Training
Behavioral · Other
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
18
States / cities
East Orange, New Jersey • Buffalo, New York • New York, New York + 15 more
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Oct 22, 2026, 5:33 AM EDT