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ClinicalTrials.gov public records Last synced Oct 22, 2026, 3:34 AM EDT

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Showing 193–216 of 366 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Compulsive Personality Disorder Clear all
Recruiting Phase 2 Interventional

MDMA-Assisted CBT for OCD (MDMA-CBT4OCD Study)

NCT05783817
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
3,4-Methyl enedioxy methamphetamine, Methamphetamine, Cognitive Behavioral Therapy (CBT)
Drug · Behavioral
Lead sponsor
Carolyn Rodriguez
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Oct 22, 2026, 3:34 AM EDT
Recruiting Phase 2 Interventional

Study of Dextromethorphan in OCD and Related Disorders

NCT04899687
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Illness Anxiety Disorder, Body Dysmorphic Disorders, Somatic Symptom Disorder
Interventions
Fluoxetine, Dextromethorphan
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2028
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 22, 2026, 3:34 AM EDT
Completed Phase 2 Interventional Results available

Novel Medication Strategies Targeting Brain Mechanisms in Pediatric OCD

NCT01695291
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Minocycline, Placebo
Drug · Other
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
8 Years to 20 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
2
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 13, 2019 · Synced Oct 22, 2026, 3:34 AM EDT
Completed Phase 2 Interventional Results available

Ketamine Infusion for Obsessive-Compulsive Disorder

NCT01349231
View directory record Official record
Conditions
Obsessive-compulsive Disorder
Interventions
ketamine
Drug
Lead sponsor
Yale University
Other
Eligibility
18 Years to 65 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jun 9, 2014 · Synced Oct 22, 2026, 3:34 AM EDT
Completed Phase 2Phase 3 Interventional Results available

Tolcapone in Obsessive Compulsive Disorder

NCT03348930
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Tolcapone 200 MG
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Apr 7, 2022 · Synced Oct 22, 2026, 3:34 AM EDT
Recruiting Not applicable Interventional

Connectomic Deep Brain Stimulation for Obsessive Compulsive Disorder

NCT05160129
View directory record Official record
Conditions
Obsessive Compulsive Disorder (OCD)
Interventions
Selective focal stimulation of ALIC-pathways
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 25, 2026 · Synced Oct 22, 2026, 3:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Exposure-Focused Family-Based CBT for Youth With ASD and Comorbid Anxiety

NCT01919970
View directory record Official record
Conditions
Autism, Asperger's Syndrome, Pervasive Developmental Disorder Not Otherwise Specified, Generalized Anxiety Disorder, Social Phobia, Separation Anxiety Disorder, Obsessive-compulsive Disorder, Specific Phobia
Interventions
Cognitive Behavioral Therapy, Treatment as usual
Other
Lead sponsor
University of South Florida
Other
Eligibility
6 Years to 12 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
St. Petersburg, Florida
Source: ClinicalTrials.gov public record
Updated Jun 14, 2019 · Synced Oct 22, 2026, 3:34 AM EDT
Not listed Phase 2 Interventional

Phase II Randomized Study of Intravenous Versus Oral Clomipramine in Patients With Obsessive Compulsive Disorder

NCT00004310
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Clomipramine
Drug
Lead sponsor
National Center for Research Resources (NCRR)
NIH
Eligibility
18 Years to 55 Years
Enrollment
76 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1999
U.S. locations
2
States / cities
Stanford, California • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 22, 2026, 3:34 AM EDT
Completed Not applicable Interventional

Cognitive Bias Modification for OCD

NCT03799419
View directory record Official record
Conditions
Obsessive-Compulsive Disorder, Obsessive-compulsive Disorders and Symptoms
Interventions
Cognitive bias modification for interpretation bias, Psychoeducation, Approach avoidance training, Inactive sham approach avoidance training
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years and older
Enrollment
64 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 24, 2024 · Synced Oct 22, 2026, 3:34 AM EDT
Terminated Phase 3 Interventional

Long-term Safety Study of Adjunctive Troriluzole in Subjects With Obsessive Compulsive Disorder

NCT04708834
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Troriluzole (BHV-4157)
Drug
Lead sponsor
Biohaven Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 65 Years
Enrollment
772 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
147
States / cities
Chandler, Arizona • Phoenix, Arizona • Little Rock, Arkansas + 119 more
Source: ClinicalTrials.gov public record
Updated Feb 25, 2026 · Synced Oct 22, 2026, 3:34 AM EDT
Completed Phase 2 Interventional

A Study in Patients With Trichotillomania

NCT03797521
View directory record Official record
Conditions
Trichotillomania
Interventions
SXC-2023, Placebo
Drug
Lead sponsor
Promentis Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
13
States / cities
Pico Rivera, California • Riverside, California • North Miami, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Oct 28, 2021 · Synced Oct 22, 2026, 3:34 AM EDT
Completed Not applicable Interventional Results available

D-Cycloserine Augmentation to CBT With Exposure and Response Prevention in Adults and Adolescents With OCD

NCT01172873
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
D-cycloserine, Exposure and Response Prevention (EX/RP)
Drug · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
12 Years to 17 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 19, 2014 · Synced Oct 22, 2026, 3:34 AM EDT
Withdrawn Not applicable Interventional

Waitlist-Control Trial of Smartphone CBT for Obsessive-Compulsive Disorder (OCD)

NCT03767491
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Smartphone-delivered CBT for OCD
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 8, 2022 · Synced Oct 22, 2026, 3:34 AM EDT
Completed Not applicable Interventional

Efficacy of COMB (Comprehensive Behavioral) Model of Treatment of Trichotillomania

NCT01878110
View directory record Official record
Conditions
Trichotillomania, Hair-Pulling Disorder
Interventions
COMB
Behavioral
Lead sponsor
American University
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2013
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 15, 2015 · Synced Oct 22, 2026, 3:34 AM EDT
Completed Phase 2 Interventional

Preventive Measures for Childhood-Onset Obsessive-Compulsive Disorder and Tic Disorders (PANDAS Subgroup)

NCT00001359
View directory record Official record
Conditions
Mental Disorder Diagnosed in Childhood, Obsessive Compulsive Disorder, Streptococcal Infection, Tic Disorder
Interventions
Penicillin or Placebo
Drug
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1993 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 22, 2026, 3:34 AM EDT
Not listed No phase listed Observational

A Study of Gene Polymorphisms Associated With Specific Presentations of Sexual Addiction

NCT02844985
View directory record Official record
Conditions
Sexual Addiction
Interventions
No Intervention
Other
Lead sponsor
American Foundation for Addiction Research
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
8
States / cities
Scottsdale, Arizona • Wickenburg, Arizona • Los Angeles, California + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 13, 2020 · Synced Oct 22, 2026, 3:34 AM EDT
Recruiting Not applicable Interventional

Interpretation Bias as a Mechanism of Treatment Response in OCD

NCT05224414
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Cognitive bias modification for interpretation bias, Psychoeducation
Behavioral
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 18, 2026 · Synced Oct 22, 2026, 3:34 AM EDT
Completed No phase listed Observational

Child and Adolescent OCD Outcomes From Exposure and Response Prevention Video Teletherapy Treatment

NCT06466447
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Exposure and response prevention therapy
Behavioral
Lead sponsor
NOCD
Industry
Eligibility
4 Years to 17 Years
Enrollment
2,173 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 26, 2024 · Synced Oct 22, 2026, 3:34 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Neuroimaging Biomarkers for Predicting rTMS Response in OCD

NCT04286126
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Active bilateral DMPFC, Active right-sided OFC
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 80 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Apr 18, 2023 · Synced Oct 22, 2026, 3:34 AM EDT
Completed Phase 2 Interventional Results available

Memantine Augmentation in Treatment-Resistant Adults With Obsessive-Compulsive Disorder

NCT00956085
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Memantine
Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 21, 2017 · Synced Oct 22, 2026, 3:34 AM EDT
Completed Phase 3 Interventional

Treatment of Obsessive-Compulsive Disorder (OCD) in Children

NCT00000384
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Cognitive Behavior Therapy, Educational Support, Sertraline
Behavioral · Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
8 Years to 16 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
1997 – 2002
U.S. locations
2
States / cities
Durham, North Carolina • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 22, 2016 · Synced Oct 22, 2026, 3:34 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

A Controlled Trial of Daily Cognitive-Behavioral Therapy for Pediatric Obsessive-Compulsive Disorder

NCT00369642
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Cognitive-behavioral therapy
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
7 Years to 17 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2006
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Aug 9, 2010 · Synced Oct 22, 2026, 3:34 AM EDT
Completed Not applicable Interventional Results available

Trial of Aripiprazole in Trichotillomania

NCT00947154
View directory record Official record
Conditions
Trichotillomania
Interventions
aripiprazole
Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Jun 16, 2015 · Synced Oct 22, 2026, 3:34 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Fear Extinction and Mechanisms of Change in Obsessive Compulsive Disorder

NCT02467374
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Behavior Therapy
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 60 Years
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 31, 2022 · Synced Oct 22, 2026, 3:34 AM EDT