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Showing 1–24 of 485 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Concussion Clear all
Completed Not applicable Interventional

Clinical Trial to Evaluate the Safety and Efficacy of MeRT Treatment in Post-Traumatic Stress Disorder

NCT02990793
View directory record Official record
Conditions
PostTraumatic Stress Disorder, Traumatic Brain Injury, Postconcussive Symptoms
Interventions
Active MeRT Treatment, Sham MeRT Treatment
Device
Lead sponsor
Wave Neuroscience
Industry
Eligibility
18 Years to 65 Years
Enrollment
158 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
8
States / cities
Costa Mesa, California • Long Beach, California • San Diego, California + 5 more
Source: ClinicalTrials.gov public record
Updated Jan 14, 2026 · Synced Jul 21, 2026, 7:05 AM EDT
Withdrawn Not applicable Interventional

Fundamental and Applied Concussion Recovery Modality Research and Development: Applications for the Enhanced Recovery

NCT05062148
View directory record Official record
Conditions
Traumatic Brain Injury, Post-Concussion Syndrome, Concussion, Brain
Interventions
Float-REST, Photobiomodulation
Other
Lead sponsor
West Virginia University
Other
Eligibility
14 Years to 17 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Dec 22, 2022 · Synced Jul 21, 2026, 7:05 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Prospective Study of Brain Network Activation (BNA) Changes in High School Athletes Following Concussion

NCT01673464
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
ElMindA Ltd
Industry
Eligibility
13 Years to 18 Years
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 8, 2015 · Synced Jul 21, 2026, 7:05 AM EDT
Completed No phase listed Observational

S-100B as Pre-Head CT Scan Screening Test After Mild Traumatic Brain Injury

NCT00717301
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
University of Rochester
Other
Eligibility
Not listed
Enrollment
1,252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
6
States / cities
Albany, New York • Buffalo, New York • Cooperstown, New York + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 11, 2015 · Synced Jul 21, 2026, 7:05 AM EDT
Completed Not applicable Interventional

Telephone Follow-Up on Outcome After Mild Traumatic Brain Injury

NCT00483444
View directory record Official record
Conditions
Brain Concussion
Interventions
Scheduled telephone follow-up
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
16 Years to 80 Years
Enrollment
366 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Nov 8, 2017 · Synced Jul 21, 2026, 7:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Live Video Mind-body Treatment to Prevent Persistent Symptoms Following mTBI

NCT05524402
View directory record Official record
Conditions
MTBI - Mild Traumatic Brain Injury, Anxiety
Interventions
TOR-C 1, TOR-C 2
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 35 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 19, 2025 · Synced Jul 21, 2026, 7:05 AM EDT
Completed Not applicable Interventional

Web-Based Self-Monitoring Activity-Restriction and Relaxation Training Program for Kids With Mild Traumatic Brain Injury

NCT03498495
View directory record Official record
Conditions
Brain Injury Traumatic Mild
Interventions
Self-Monitoring Activity-restriction and Relaxation Training (SMART)
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
11 Years to 18 Years
Enrollment
74 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 9, 2023 · Synced Jul 21, 2026, 7:05 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Crisis Response Planning in Military Personnel With Mild Traumatic Brain Injury

NCT07327567
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Suicide Prevention, Suicide Risk | Patient, Suicide Risk, Suicide Risk Factor
Interventions
Crisis Response Planning
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Fort Hood, Texas
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Jul 21, 2026, 7:05 AM EDT
Completed Not applicable Interventional

Hyperbaric Oxygen Therapy for Post-Concussion Syndrome

NCT05643482
View directory record Official record
Conditions
Post-Concussion Syndrome
Interventions
Hyperbaric Oxygen Treatment, Placebo gas
Device · Other
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Jul 21, 2026, 7:05 AM EDT
Not yet recruiting No phase listed Observational

Safety and Outcomes of MUSE Stem Cell Therapy in Individuals With Traumatic Brain Injury

NCT07326059
View directory record Official record
Conditions
Traumatic Brain Injury, Traumatic Brain Injury (TBI) Patients, Traumatic Brain Injury (TBI); Concussion, Initial Encounter, Traumatic Brain Injury (TBI); Concussion, Subsequent Encounter, Traumatic Brain Injury With Brief Loss of Consciousness, Traumatic Brain Injury With Persistent Cognitive Deficits
Interventions
MUSE Stem Cell Therapy
Biological
Lead sponsor
Healing Hope International
Other
Eligibility
6 Years to 75 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2028 – 2036
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 9, 2026 · Synced Jul 21, 2026, 7:05 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Enhancing Cognitive and Neurobehavioral Functions After Repetitive Traumatic Brain Injuries (rTBI) in Retired NFL Players and Military Veterans.

NCT02699476
View directory record Official record
Conditions
Traumatic Brain Injury, Concussion, Mild Cognitive Disorder
Interventions
Psycho-Social Therapy, Cognitive Behavioral Computer Training, Interactive Trainer-Subject Sessions, Active Control Games
Behavioral · Device
Lead sponsor
Brain & Body Health Foundation
Other
Eligibility
25 Years to 55 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Lakeway, Texas
Source: ClinicalTrials.gov public record
Updated Mar 3, 2016 · Synced Jul 21, 2026, 7:05 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Cerebral Blood Flow Regulation and Concussions

NCT02754206
View directory record Official record
Conditions
Brain Concussion, Post-Concussion Syndrome
Interventions
Not listed
Lead sponsor
Southern Methodist University
Other
Eligibility
18 Years to 30 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 13, 2021 · Synced Jul 21, 2026, 7:05 AM EDT
Recruiting Not applicable Interventional

Wearable Technology to Characterize and Treat mTBI Subtypes: Biofeedback-Based Precision Rehabilitation

NCT06381674
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Concussion, Rehabilitation, Balance Impairment
Interventions
Vestibular therapy for mTBI augmented with audio and visual real-time biofeedback, Vestibular therapy for mTBI
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
3
States / cities
Portland, Oregon • San Antonio, Texas • Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Oct 13, 2025 · Synced Jul 21, 2026, 7:05 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluation and Validation of a Multimodal Brain Function Biomarker With NPC

NCT04074486
View directory record Official record
Conditions
Brain Injuries, Concussion, Mild, Concussion, Brain, Near Point Convergence, Concussion, Intermediate
Interventions
BrainScope Ahead 300iP-O, SCAT5, Near Point Convergence
Device · Diagnostic Test
Lead sponsor
BrainScope Company, Inc.
Industry
Eligibility
13 Years to 50 Years
Enrollment
1,318 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2022
U.S. locations
6
States / cities
Fayetteville, Arkansas • Storrs, Connecticut • Miami, Florida + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 9, 2022 · Synced Jul 21, 2026, 7:05 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Balance and Mild Traumatic Brain Injury (TBI)

NCT01377454
View directory record Official record
Conditions
Brain Concussion, Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
12 Years to 40 Years
Enrollment
47 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Aug 7, 2012 · Synced Jul 21, 2026, 7:05 AM EDT
Recruiting Not applicable Interventional

Treating Mild Traumatic Brain Injury With High Definition Transcranial Direct Current Stimulation

NCT04869059
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Transcranial direct current stimulation, sham tDCS
Device
Lead sponsor
The University of Texas at Dallas
Other
Eligibility
18 Years to 75 Years
Enrollment
136 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Sep 22, 2025 · Synced Jul 21, 2026, 7:05 AM EDT
Completed Not applicable Interventional

Symptom-Targeted Approach to Rehabilitation for Concussion

NCT05091970
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Manualized cognitive rehabilitation for mild traumatic brain injury (mTBI)
Procedure
Lead sponsor
South Texas Veterans Health Care System
Federal
Eligibility
18 Years to 65 Years
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
2
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Jul 21, 2026, 7:05 AM EDT
Completed Not applicable Interventional

Comparative Effectiveness of Family Problem-Solving Therapy (F-PST) for Adolescent TBI

NCT02368366
View directory record Official record
Conditions
Tbi, Intracranial Edema, Brain Edema, Craniocerebral Trauma, Head Injury, Brain Hemorrhage, Traumatic, Subdural Hematoma, Brain Concussion, Head Injuries, Closed, Epidural Hematoma, Cortical Contusion, Wounds and Injuries, Disorders of Environmental Origin, Trauma, Nervous System, Brain Injuries
Interventions
Therapist Guided Face to Face Family Problem Solving, Therapist Guided Online Family Problem Solving, Self-Guided Online Family Problem Solving
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
14 Years to 19 Years
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
5
States / cities
Denver, Colorado • Cincinnati, Ohio • Cleveland, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 28, 2018 · Synced Jul 21, 2026, 7:05 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain Dynamics in Response to Jugular Vein Compression

NCT03236389
View directory record Official record
Conditions
Concussion, Mild
Interventions
Q Collar
Device
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
7 Years to 40 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 25, 2023 · Synced Jul 21, 2026, 7:05 AM EDT
Recruiting Phase 2Phase 3 Interventional

Randomized Controlled Trial of Treatment to Optimize Heart Rate Variability for Persistent Post-Concussion Symptoms

NCT07071350
View directory record Official record
Conditions
Autonomic Nervous System Disease, Concussive Injury, Mild Traumatic Brain Injury, Post Traumatic Stress Disorder, Persistent Post Concussion Syndrome
Interventions
HRV Coherence Ratio, NSI, Pittsburgh Sleep Quality Index (PSQI), Quantitative Sleep Measures, Patient Global Impression of Change (PGIC), Cognitive Performance/NIH Toolbox Cognitive Battery, Pain Interference/TBI-QoL Pain Interference Short-Form, Patient Health Questionnaire-9 (PHQ-9), PTSD Checklist for DSM-5 (PCL-5), HRV Biofeedback (HRV-B), Psychoeducational (Edu) Comparator Intervention
Other · Behavioral
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
148 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 16, 2025 · Synced Jul 21, 2026, 7:05 AM EDT
Recruiting Not applicable Interventional

Improving Cognitive Rehabilitation Outcomes

NCT07055633
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Posttraumatic Stress Disorder
Interventions
CCT+MBLT, CCT+ION
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
San Diego, California • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Apr 23, 2026 · Synced Jul 21, 2026, 7:05 AM EDT
Recruiting Phase 2 Interventional

Veterans' Cognitive Function, Mental Health, and Quality of Life After Hyperbaric Oxygen Therapy

NCT07214415
View directory record Official record
Conditions
TBI Traumatic Brain Injury, PTSD - Post Traumatic Stress Disorder, Post Concussive Syndrome
Interventions
Hyperbaric Oxygen Therapy
Drug
Lead sponsor
Summit Hyperbarics and Wellness
Other
Eligibility
18 Years to 75 Years
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Oct 8, 2025 · Synced Jul 21, 2026, 7:05 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Objective Dual-task Turning Measures for Return-to-duty Assessments

NCT03892291
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Gait, Balance, Veterans, Mobility
Interventions
Not listed
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years to 50 Years
Enrollment
185 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
6
States / cities
Fort Carson, Colorado • Minneapolis, Minnesota • Portland, Oregon + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 5, 2025 · Synced Jul 21, 2026, 7:05 AM EDT
Completed Not applicable Interventional

Collaborative Care Model for the Treatment of Persistent Symptoms After Concussion Among Youth

NCT03034720
View directory record Official record
Conditions
Concussion, Brain, TBI, Depression, Anxiety
Interventions
Collaborative Care
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
11 Years to 18 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 7, 2021 · Synced Jul 21, 2026, 7:05 AM EDT