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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Concussion, Cerebral Clear all
Completed No phase listed Observational

Non-blinded Data Collection Study of Concussion Using the BrainPulse(TM)

NCT02812225
View directory record Official record
Conditions
Brain Concussion, Mild Traumatic Brain Injury
Interventions
BrainPulse
Device
Lead sponsor
Jan Medical, Inc.
Industry
Eligibility
5 Years and older
Enrollment
406 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
3
States / cities
Boston, Massachusetts • Cincinnati, Ohio • Johnson City, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 8, 2022 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Phase 2 Interventional Results available

Ghrelin (OXE--103) for Acute Concussion Management

NCT04558346
View directory record Official record
Conditions
Concussion, Brain, Traumatic Brain Injury
Interventions
Ghrelin (OXE-103), Placebo
Drug
Lead sponsor
Michael Rippee
Other
Eligibility
18 Years to 60 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated May 20, 2024 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Not applicable Interventional

Randomized Controlled Trial for Vestibular Treatment in Concussion

NCT03600324
View directory record Official record
Conditions
Vestibular Disorder, Mild Traumatic Brain Injury
Interventions
T-REV
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 50 Years
Enrollment
121 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
4
States / cities
Colorado Springs, Colorado • Marine Corps Base Camp Lejeune, North Carolina • Pittsburgh, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 17, 2026, 5:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Field Implementation of iDETECT

NCT02529618
View directory record Official record
Conditions
Concussion, Brain Trauma
Interventions
integrated Display Enhanced Testing for Cognitive Impairment and mild traumatic brain injury (iDETECT), Riddell High Impact Technology (HIT) System, i1 Biometrics Vector Mouth Guard
Device
Lead sponsor
Emory University
Other
Eligibility
14 Years and older
Enrollment
124 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
4
States / cities
Atlanta, Georgia • College Park, Georgia • Marietta, Georgia + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 3, 2016 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Not applicable Interventional

Stationary Bike Study

NCT02640599
View directory record Official record
Conditions
Vertigo, Concussion, Dizziness
Interventions
Vestibular Rehabilitation + Aerobic Exercise, Vestibular Rehabilitation
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 70 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 8, 2020 · Synced Sep 17, 2026, 5:15 AM EDT
Withdrawn Not applicable Interventional

Cranial-nerve Non-invasive Neuromodulation (CN-NINM) for Balance Deficits After Mild Traumatic Brain Injury (Pilot Trial)

NCT02109198
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Active CN-NINM PoNS, Sham CN-NINM PoNS
Device
Lead sponsor
U.S. Army Medical Research and Development Command
Federal
Eligibility
18 Years to 50 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
2
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 1, 2015 · Synced Sep 17, 2026, 5:15 AM EDT
Completed No phase listed Observational

EyeBOX Concussion Study and Registry

NCT03966404
View directory record Official record
Conditions
Concussion, Brain, Mild Traumatic Brain Injury
Interventions
EyeBOX device
Diagnostic Test
Lead sponsor
Oculogica, Inc.
Industry
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Sep 6, 2023 · Synced Sep 17, 2026, 5:15 AM EDT
Enrolling by invitation No phase listed Observational

Transforming Research and Clinical Knowledge in Traumatic Brain Injury (TRACK-TBI) Precision Medicine Phase 2 Option 1

NCT04602806
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2030
U.S. locations
5
States / cities
San Francisco, California • Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania + 2 more
Source: ClinicalTrials.gov public record
Updated Sep 13, 2026 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

High-Definition Transcranial Direct Current Stimulation (HD-tDCS) for Sensory Deficits in Complex Traumatic Brain Injury

NCT03799458
View directory record Official record
Conditions
Mild Traumatic Brain Injury
Interventions
Active High-definition transcranial direct current stimulation (HD-tDCS), Sham High-definition transcranial direct current stimulation (HD-tDCS)
Device
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years to 59 Years
Enrollment
79 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Apr 7, 2025 · Synced Sep 17, 2026, 5:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

Concussion Testing: A Novel Non-invasive Concussion Detection Device

NCT02370914
View directory record Official record
Conditions
Concussion
Interventions
Nautilus NeuroWaveTM System, SCAT
Device · Behavioral
Lead sponsor
Jan Medical, Inc.
Industry
Eligibility
14 Years to 18 Years · Male only
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Los Altos, California
Source: ClinicalTrials.gov public record
Updated Aug 1, 2022 · Synced Sep 17, 2026, 5:15 AM EDT
Terminated Phase 1 Interventional

Effects of Psilocybin in Concussion Headache

NCT03806985
View directory record Official record
Conditions
Post-Traumatic Headache
Interventions
Placebo oral capsule, Low Dose Psilocybin, High Dose Psilocybin
Drug
Lead sponsor
Yale University
Other
Eligibility
21 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
West Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Oct 11, 2023 · Synced Sep 17, 2026, 5:15 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Measure of Cerebrovascular Dysfunction After TBI With fNIRS

NCT01789164
View directory record Official record
Conditions
Traumatic Brain Injury, Post-concussion Syndrome
Interventions
Not listed
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 60 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Rockville, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 16, 2019 · Synced Sep 17, 2026, 5:15 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

The COACH Project: Combined Online Assistance for Caregiver Health

NCT03123224
View directory record Official record
Conditions
Traumas, Brain, Alzheimer Disease, Dementia, Head Injury, Concussion, Brain, TBI
Interventions
Combined Aerobic and Resistance Exercise + Caregiver Skills Training, Stretching Balance and Flexibility + Caregiver Skills Training
Behavioral
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
18 Years to 85 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 17, 2018 · Synced Sep 17, 2026, 5:15 AM EDT
Recruiting Not applicable Interventional

The Influence of Prescribed Exercise on Pain Related Fear Following Concussion in Collegiate Athletes

NCT06246669
View directory record Official record
Conditions
Concussion, Brain
Interventions
Treadmill Walking
Behavioral
Lead sponsor
University of Virginia
Other
Eligibility
18 Years to 25 Years
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Dec 8, 2024 · Synced Sep 17, 2026, 5:15 AM EDT
Not listed Phase 1 Interventional

ATCell™ Expanded Autologous, Adipose-Derived Mesenchymal Stem Cells Deployed Via Intravenous Infusion

NCT04744051
View directory record Official record
Conditions
Post-Concussion Syndrome
Interventions
50 Adipose Derived Stem Cell Infusion, 150 Adipose Derived Stem Cell Infusion, 300 Adipose Derived Stem Cell Infusion, Placebo Infusion
Drug
Lead sponsor
American CryoStem Corporation
Industry
Eligibility
18 Years to 65 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
La Mesa, California
Source: ClinicalTrials.gov public record
Updated Jun 8, 2023 · Synced Sep 17, 2026, 5:15 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Contributions of mTBI to Neurodegeneration Due to Chronic Traumatic Encephalopathy (CTE) and Alzheimer's Disease (AD)

NCT04124029
View directory record Official record
Conditions
Mild Traumatic Brain Injury, Moderate Traumatic Brain Injury, Mild Cognitive Impairment
Interventions
No Intervention is used for this study but all subjects will be asked to complete electroencephalogram (EEG) testing and an MRI scan., No intervention is used for this study but all subjects will be asked to complete a venous blood draw procedure and a lumbar puncture procedure.
Device · Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
30 Years to 90 Years
Enrollment
800 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 31, 2026 · Synced Sep 17, 2026, 5:15 AM EDT
Not yet recruiting Not applicable Interventional

SPINEPASS: SPINE Self-management Techniques for Persistent Headache After Concussion: Physical Therapy Targeting Autonomic and Dura Mater Function.

NCT06882239
View directory record Official record
Conditions
Persistent Post-concussive Symptoms, Post Traumatic Headache
Interventions
SPINEPASS Physical Therapy, Standard Physical Therapy
Other
Lead sponsor
The University of Queensland
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 17, 2025 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Ketone Supplementation in Adolescents Post-Concussion

NCT04079907
View directory record Official record
Conditions
Concussion, Mild, Concussion, Severe, Concussion, Brain, Concussive Injury, Sport Injury, Sports Injuries in Children
Interventions
Ketone, Placebo
Dietary Supplement
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
13 Years to 19 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated May 9, 2022 · Synced Sep 17, 2026, 5:15 AM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Implementation of an Evidence-Based Educational Resource for Children With Mild Traumatic Brain Injury

NCT07414303
View directory record Official record
Conditions
Concussion, Mild Traumatic Brain Injury
Interventions
Post-mTBI Educational Resource
Other
Lead sponsor
Baylor Research Institute
Other
Eligibility
8 Years to 99 Years
Enrollment
14 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
3
States / cities
Frisco, Texas • Temple, Texas
Source: ClinicalTrials.gov public record
Updated Feb 16, 2026 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Sildenafil for Cerebrovascular Dysfunction in Chronic Traumatic Brain Injury.

NCT01762475
View directory record Official record
Conditions
Traumatic Brain Injury, Post-concussive Syndrome
Interventions
Sildenafil
Drug
Lead sponsor
Uniformed Services University of the Health Sciences
Federal
Eligibility
18 Years to 55 Years
Enrollment
59 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Dec 31, 2015 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dual-task Assessment and Rehabilitation for Individuals With Residual Symptoms After mTBI

NCT03478059
View directory record Official record
Conditions
Brain Injury Traumatic Mild, Concussion, Brain
Interventions
Cognitive and Motor Dual-task Intervention
Behavioral
Lead sponsor
Allina Health System
Other
Eligibility
18 Years to 50 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 29, 2019 · Synced Sep 17, 2026, 5:15 AM EDT
Completed Not applicable Interventional

Brain Health & Wellness Classes for Veterans With Traumatic Brain Injury

NCT06150196
View directory record Official record
Conditions
Brain Injury Traumatic Mild, Post-traumatic Stress Disorder
Interventions
Mindfulness-based Stress Reduction class, Brain Health Education class
Behavioral
Lead sponsor
East Bay Institute for Research and Education
Other
Eligibility
18 Years to 75 Years
Enrollment
117 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Martinez, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 17, 2026, 5:15 AM EDT
Terminated Not applicable Interventional

Cooling Helmets to Decrease Concussion Symptoms

NCT05473897
View directory record Official record
Conditions
Concussion, Mild, TBI (Traumatic Brain Injury)
Interventions
Catalyst Cryohelmet
Device
Lead sponsor
Corewell Health South
Other
Eligibility
19 Years to 65 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Saint Joseph, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 28, 2024 · Synced Sep 17, 2026, 5:15 AM EDT
Active, not recruiting Phase 2 Interventional

Pilot rTMS for AUD+mTBI

NCT03995173
View directory record Official record
Conditions
Alcohol Use Disorder, Mild Traumatic Brain Injury, Post-traumatic Stress Disorder
Interventions
repetitive transcranial magnetic stimulation
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
22 Years to 65 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 25, 2025 · Synced Sep 17, 2026, 5:15 AM EDT