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ClinicalTrials.gov public records Last synced Oct 28, 2026, 6:48 AM EDT

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Showing 217–240 of 370 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Conduction Defects Clear all
Completed Not applicable Interventional Results available

MADIT-CRT: Multicenter Automatic Defibrillator Implantation With Cardiac Resynchronization Therapy

NCT00180271
View directory record Official record
Conditions
Tachycardia, Congestive Heart Failure
Interventions
Cardiac resynchronization therapy with defibrillation, Implantable Cardioverter Defibrillator (ICD)
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
21 Years and older
Enrollment
1,820 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2010
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 19, 2018 · Synced Oct 28, 2026, 6:48 AM EDT
Completed Phase 2 Interventional

Double Blind Placebo Controlled Dose Ranging Study of the Efficacy and Safety of SSR149744c 100 or 300 mg for the Prevention of ventrICular ARrhythmia-triggered Icd interventiOnS

NCT00232297
View directory record Official record
Conditions
Arrhythmia, Tachycardia, Ventricular, Ventricular Fibrillation
Interventions
SSR149744C
Drug
Lead sponsor
Sanofi
Industry
Eligibility
21 Years and older
Enrollment
153 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated May 8, 2012 · Synced Oct 28, 2026, 6:48 AM EDT
Enrolling by invitation Not applicable Interventional

Functional Substrate-Only Guided VT Ablation

NCT06464315
View directory record Official record
Conditions
Ventricular Tachycardia, Sudden Cardiac Death
Interventions
Functional Substrate-Only Mapping without VT Induction, Standard-of-Care Mapping/Imaging
Procedure
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 90 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Mar 25, 2026 · Synced Oct 28, 2026, 6:48 AM EDT
Completed Phase 4 Interventional

Prevention of Atrial Arrhythmia in Patients Without Atrioventricular (AV) Conduction Disease

NCT01170611
View directory record Official record
Conditions
Sinus Node Dysfunction, Brady Tachy Syndrome
Interventions
PACEMAKER SYMPHONY 2550
Device
Lead sponsor
LivaNova
Industry
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
10
States / cities
Birmingham, Alabama • Mesa, Arizona • Los Angeles, California + 7 more
Source: ClinicalTrials.gov public record
Updated Jul 27, 2010 · Synced Oct 28, 2026, 6:48 AM EDT
Completed Phase 4 Interventional Results available

Safety of Sugammadex for the Reversal of Neuromuscular Blockade in American Society of Anesthesiologists (ASA) Class 3 or 4 Participants (MK-8616-145)

NCT03346057
View directory record Official record
Conditions
Reversal of Neuromuscular Blockade
Interventions
Sugammadex 2 mg/kg, Sugammadex 4 mg/kg, Sugammadex 16 mg/kg, Neostigmine + Glycopyrrolate, Rocuronium, Vecuronium
Drug
Lead sponsor
Merck Sharp & Dohme LLC
Industry
Eligibility
18 Years and older
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
20
States / cities
Birmingham, Alabama • Tucson, Arizona • Loma Linda, California + 15 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2020 · Synced Oct 28, 2026, 6:48 AM EDT
Completed No phase listed Observational

The Simple ECG Monitoring Trial (Comparison of a Novel Recording System With a Standard Holter Monitor)

NCT01382953
View directory record Official record
Conditions
Syncope, Pre-syncope, Atrial Fibrillation, Supraventricular Tachycardia
Interventions
Standard Holter/Investigational patch
Device
Lead sponsor
Seattle Institute for Cardiac Research
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011
U.S. locations
2
States / cities
Chicago, Illinois • Enumclaw, Washington
Source: ClinicalTrials.gov public record
Updated Jan 10, 2012 · Synced Oct 28, 2026, 6:48 AM EDT
Not listed No phase listed Observational

Genetics of QT Prolongation With Antiarrhythmics

NCT02439658
View directory record Official record
Conditions
Long QT Syndrome, Drug Toxicity
Interventions
Dofetilide and/or sotalol
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2023
U.S. locations
5
States / cities
Aurora, Colorado • Boston, Massachusetts • Rochester, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 4, 2022 · Synced Oct 28, 2026, 6:48 AM EDT
Completed Not applicable Interventional Results available

Inappropriate Shock Reduction wIth PARAD+ Rhythm DiScrimination

NCT01410552
View directory record Official record
Conditions
Tachycardia
Interventions
PARADYM DR model 8550; PARADYM CRT model 8750; PARADYM RF DR model 9550; PARADYM RF CRT model 9750; PARADYM RF CRT SonR model 9770
Device
Lead sponsor
MicroPort CRM
Industry
Eligibility
18 Years and older
Enrollment
1,013 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
27
States / cities
Mesa, Arizona • Peoria, Arizona • Phoenix, Arizona + 23 more
Source: ClinicalTrials.gov public record
Updated Mar 22, 2019 · Synced Oct 28, 2026, 6:48 AM EDT
Completed No phase listed Observational Results available

Ondansetron and the QT Interval In Adult Emergency Department Patients

NCT01759420
View directory record Official record
Conditions
Ondansetron
Interventions
Ondansetron
Drug
Lead sponsor
C.R.Darnall Army Medical Center
Federal
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
2
States / cities
Fort Hood, Texas • Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jun 26, 2014 · Synced Oct 28, 2026, 6:48 AM EDT
Active, not recruiting Phase 3 Interventional

Surveillance and Treatment to Prevent Fetal Atrioventricular Block Likely to Occur Quickly (STOP BLOQ)

NCT04474223
View directory record Official record
Conditions
AVB - Atrioventricular Block, Fetal AVB
Interventions
Dexamethasone, IVIG
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older · Female only
Enrollment
1,300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2029
U.S. locations
23
States / cities
Phoenix, Arizona • Los Angeles, California • Palo Alto, California + 17 more
Source: ClinicalTrials.gov public record
Updated Aug 25, 2026 · Synced Oct 28, 2026, 6:48 AM EDT
Completed Not applicable Interventional Results available

Adaptive CRT Effect on Electrical Dyssynchrony

NCT02543281
View directory record Official record
Conditions
Cardiomyopathy, Heart Failure, Left Bundle Branch Block
Interventions
Adaptive cardiac resynchronization therapy, Conventional Cardiac Resynchronization Therapy
Device
Lead sponsor
Larisa Tereshchenko
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2021
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 20, 2025 · Synced Oct 28, 2026, 6:48 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Personalized Therapy Study - Intrinsic Antitachycardia Pacing Post-Approval Study (iATP PAS)

NCT04496518
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
Intrinsic Antitachycardia Pacing (iATP) Therapy
Device
Lead sponsor
Medtronic
Industry
Eligibility
Not listed
Enrollment
2,200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2028
U.S. locations
51
States / cities
Chandler, Arizona • Little Rock, Arkansas • Chula Vista, California + 44 more
Source: ClinicalTrials.gov public record
Updated Oct 20, 2025 · Synced Oct 28, 2026, 6:48 AM EDT
Completed Phase 2 Interventional Results available

Long-term Efficacy Study of Sodium Channel Blocker in LQT3 Patients

NCT01648205
View directory record Official record
Conditions
Long QT Syndrome
Interventions
Placebo, Ranolazine
Drug
Lead sponsor
University of Rochester
Other
Eligibility
21 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2018
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 7, 2022 · Synced Oct 28, 2026, 6:48 AM EDT
Not listed Phase 4 Interventional

Prospective Assessment of Premature Ventricular Contractions Suppression in Cardiomyopathy(PAPS)

NCT03228823
View directory record Official record
Conditions
Ventricular Premature Beats, Contractions, or Systoles, Cardiomyopathies
Interventions
Radiofrequency ablation, Amiodarone (Antiarrhythmic drug)
Procedure · Drug
Lead sponsor
Hunter Holmes Mcguire Veteran Affairs Medical Center
Federal
Eligibility
18 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
10
States / cities
Los Angeles, California • San Francisco, California • Tampa, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Apr 14, 2021 · Synced Oct 28, 2026, 6:48 AM EDT
Completed Phase 3 Interventional Results available

Safety Study of Etripamil Nasal Spray for Patients With Paroxysmal Supraventricular Tachycardia. NODE-303

NCT04072835
View directory record Official record
Conditions
Paroxysmal Supraventricular Tachycardia
Interventions
Etripamil NS
Drug
Lead sponsor
Milestone Pharmaceuticals Inc.
Other
Eligibility
18 Years and older
Enrollment
1,116 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
61
States / cities
Gilbert, Arizona • Fremont, California • Stanford, California + 54 more
Source: ClinicalTrials.gov public record
Updated May 23, 2024 · Synced Oct 28, 2026, 6:48 AM EDT
Not listed No phase listed Observational

South Asian Arrhythmogenic Cardiomyopathy Registry

NCT04895540
View directory record Official record
Conditions
Arrhythmogenic Right Ventricular Cardiomyopathy, Arrhythmogenic Right Ventricular Dysplasia, Arrhythmogenic Ventricular Cardiomyopathy, Arrhythmogenic Cardiomyopathy, Ventricular Tachycardia, Sudden Cardiac Death
Interventions
ECG, Echocardiography, Cardiac MRI, Ambulatory ECG recording, Cardiac EP study, All study subjects will undergo sample collection for genetic testing.
Diagnostic Test · Genetic
Lead sponsor
Sheri Kashmir Institute of Medical Sciences
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 2, 2021 · Synced Oct 28, 2026, 6:48 AM EDT
Completed No phase listed Observational

Stanford Cardiac Invasive Electrophysiology Novel Computer Experience

NCT03549806
View directory record Official record
Conditions
Atrial Fibrillation, Atrial Tachycardia, Atrial Flutter, Arrhythmias, Cardiac
Interventions
No Intervention. Test is computer algorithm.
Diagnostic Test
Lead sponsor
Stanford University
Other
Eligibility
21 Years to 80 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Dec 2, 2024 · Synced Oct 28, 2026, 6:48 AM EDT
Completed Not applicable Interventional

Optimal Coronary Sinus Lead Implantation Using Intracardiac Impedography and Magnetic Resonance Imaging

NCT01129635
View directory record Official record
Conditions
Heart Failure, Systolic, Left Bundle Branch Block
Interventions
Cardiac Resynchronization Therapy (CRT) implantation
Procedure
Lead sponsor
Emory University
Other
Eligibility
Not listed
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 21, 2015 · Synced Oct 28, 2026, 6:48 AM EDT
Terminated Early Phase 1 Interventional Results available

Study of Cardiac PET/CT Imaging to Guide Ablation Treatment of Ventricular Tachycardia

NCT02962076
View directory record Official record
Conditions
Ventricular Tachycardia
Interventions
[C-11] Meta-hydroxyephedrine radioactive tracer (MHED)
Drug
Lead sponsor
Khaled Awad, MD
Other
Eligibility
18 Years to 80 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 24, 2024 · Synced Oct 28, 2026, 6:48 AM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Pathophysiology of Orthostatic Intolerance

NCT00608725
View directory record Official record
Conditions
Tachycardia, Postural Orthostatic Tachycardia Syndrome
Interventions
DAXOR, QSweat, Intrinsic Heart Rate
Radiation · Procedure · Drug
Lead sponsor
Satish R. Raj
Other
Eligibility
18 Years to 80 Years
Enrollment
260 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1996 – 2029
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 28, 2026, 6:48 AM EDT
Completed No phase listed Observational

Diagnostic Value and Safety of Flecainide Infusion Test in Brugada Syndrome

NCT02302274
View directory record Official record
Conditions
Brugada Syndrome, Arrhythmogenic Right Ventricular Cardiomyopathy
Interventions
flecainide iv
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 75 Years
Enrollment
209 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Oct 28, 2026, 6:48 AM EDT
Completed No phase listed Observational

Circulating Biomarkers and Ventricular Tachyarrhythmia

NCT01892462
View directory record Official record
Conditions
Cardiomyopathy, Ventricular Tachycardia, Ventricular Fibrillation
Interventions
Not listed
Lead sponsor
Ochsner Health System
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Apr 7, 2017 · Synced Oct 28, 2026, 6:48 AM EDT
Completed Phase 1 Interventional

Study of the Effect of GS-6615 in Subjects With LQT-3

NCT01849003
View directory record Official record
Conditions
Long QT Syndrome
Interventions
GS-6615
Drug
Lead sponsor
Gilead Sciences
Industry
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Nov 17, 2014 · Synced Oct 28, 2026, 6:48 AM EDT
Completed Not applicable Interventional Results available

Dexmedetomidine and Adenosine: Therapeutic Use for SVT

NCT01495481
View directory record Official record
Conditions
Supraventricular Tachycardia
Interventions
Dexmedetomidine, Adenosine
Drug
Lead sponsor
University of Pittsburgh
Other
Eligibility
5 Years to 30 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 28, 2017 · Synced Oct 28, 2026, 6:48 AM EDT