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ClinicalTrials.gov public records Last synced Oct 21, 2026, 7:33 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 241–264 of 322 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Confusion Clear all
Not listed No phase listed Observational

The Effect of Pediatric Patient Temperament on Postoperative Outcomes

NCT04224324
View directory record Official record
Conditions
Emergence Delirium, Temperament
Interventions
Tonsillectomy and Adeniodectomy
Procedure
Lead sponsor
Boston Children's Hospital
Other
Eligibility
2 Years to 7 Years
Enrollment
344 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 30, 2023 · Synced Oct 21, 2026, 7:33 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

EEG-Guided Analgesic Titration During General Anesthesia to Improve Early Neurocognitive Recovery in Older Patients

NCT04443517
View directory record Official record
Conditions
Postoperative Delirium
Interventions
Alpha Optimization, Emergence from anesthesia with Dexmedetomidine
Procedure · Behavioral
Lead sponsor
Columbia University
Other
Eligibility
60 Years and older
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 21, 2026, 7:33 PM EDT
Withdrawn Phase 1Phase 2 Interventional

Post Operative Delirium Study

NCT04635774
View directory record Official record
Conditions
Delirium
Interventions
Insulin, Saline
Drug
Lead sponsor
University of Kansas Medical Center
Other
Eligibility
65 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Kansas City, Kansas
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Oct 21, 2026, 7:33 PM EDT
Completed Phase 4 Interventional Results available

Efficacy of Single-Shot Dexmedetomidine Versus Placebo in Preventing Pediatric Emergence Delirium in Strabismus Surgery

NCT01901588
View directory record Official record
Conditions
Strabismus, Delirium on Emergence, Pediatric Disorders
Interventions
Dexmedetomidine, Placebo
Drug · Other
Lead sponsor
NYU Langone Health
Other
Eligibility
1 Year to 7 Years
Enrollment
63 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 11, 2016 · Synced Oct 21, 2026, 7:33 PM EDT
Terminated Phase 3 Interventional Results available

An Extension To The B1451006 Protocol To Evaluate The Safety and Efficacy of Dimebon In Subjects With Moderate-to-Severe Alzheimer's Disease

NCT01066546
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Dimebon tablet for oral administration
Drug
Lead sponsor
Pfizer
Industry
Eligibility
50 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
5
States / cities
Costa Mesa, California • Encino, California • Los Alamitos, California + 2 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2012 · Synced Oct 21, 2026, 7:33 PM EDT
Terminated Phase 3 Interventional Results available

A Study of Lanabecestat (LY3314814) in Participants With Mild Alzheimer's Disease Dementia

NCT02783573
View directory record Official record
Conditions
Alzheimer's Disease
Interventions
Lanabecestat, Placebo
Drug
Lead sponsor
AstraZeneca
Industry
Eligibility
55 Years to 85 Years
Enrollment
1,722 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
90
States / cities
Phoenix, Arizona • Scottsdale, Arizona • Tucson, Arizona + 73 more
Source: ClinicalTrials.gov public record
Updated Dec 3, 2019 · Synced Oct 21, 2026, 7:33 PM EDT
Completed Not applicable Interventional Results available

Feasibility and Acceptability of ReCognitionVR-based Cognitive Stimulation in Surgical Patients

NCT06232317
View directory record Official record
Conditions
Surgery, Delirium, Delirium, Post-Operative
Interventions
Virtual Reality Software, Traditional Orientation Methods
Other
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
60 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Oct 21, 2026, 7:33 PM EDT
Recruiting Not applicable Interventional

Clinical Trial Protocol: Alzheimer's Dementia Underlying Encephalopathy

NCT07222280
View directory record Official record
Conditions
Alzheimer Dementia, Alzheimer Disease, Delirium Confusional State, Encephalopathy, Cognitive Abnormality
Interventions
Quest AD-Detect blood test
Diagnostic Test
Lead sponsor
Covenant Health, US
Other
Eligibility
60 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
6
States / cities
Crossville, Tennessee • Harriman, Tennessee • Knoxville, Tennessee + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 29, 2025 · Synced Oct 21, 2026, 7:33 PM EDT
Completed Not applicable Interventional Results available

Postoperative Delirium: Brain Vulnerability and Recovery

NCT03110185
View directory record Official record
Conditions
Delirium, Postoperative Complications
Interventions
EEG, fcDOT, fcMRI
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
60 Years and older
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 2, 2020 · Synced Oct 21, 2026, 7:33 PM EDT
Recruiting Not applicable Interventional

Ceribell Delirium Monitor Outcomes Pilot Study

NCT07449416
View directory record Official record
Conditions
Delirium in the Intensive Care Unit
Interventions
Ceribell Delirium Monitoring System
Device
Lead sponsor
Ceribell Inc.
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
2
States / cities
Irvine, California • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Oct 21, 2026, 7:33 PM EDT
Terminated No phase listed Observational

Identifying Novel Aging Targets for Treatment of Delirium

NCT03682874
View directory record Official record
Conditions
Delirium, Dementia Alzheimers, Respiratory Failure
Interventions
Not listed
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
55 Years and older
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated Jun 30, 2021 · Synced Oct 21, 2026, 7:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Understanding Visual Confusion Using Stereoscopic Displays

NCT04957745
View directory record Official record
Conditions
Diplopia, Binocular Vision Suppression, Binocular; Fusion, With Defective Stereopsis, Monocular Diplopia
Interventions
Binocular visual confusion (unilateral opaque), Unilateral monocular visual confusion (unilateral see-through), Bilateral monocular visual confusion (bilateral see-through)
Behavioral
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
14 Years and older
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 10, 2023 · Synced Oct 21, 2026, 7:33 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Methadone for Emergence Delirium in Children Undergoing Outpatient Strabismus Surgery

NCT03778372
View directory record Official record
Conditions
Emergence Delirium, Strabismus
Interventions
Methadone
Drug
Lead sponsor
Ochsner Health System
Other
Eligibility
0 Years to 18 Years
Enrollment
55 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Jefferson, Louisiana
Source: ClinicalTrials.gov public record
Updated Jul 19, 2022 · Synced Oct 21, 2026, 7:33 PM EDT
Active, not recruiting No phase listed Observational

The BRAIN Intensive Care Unit (ICU) Study: Bringing to Light the Risk Factors

NCT00392795
View directory record Official record
Conditions
Delirium, Cognition Disorders, Dementia
Interventions
Not listed
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
826 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2026
U.S. locations
2
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Oct 21, 2026, 7:33 PM EDT
Completed Not applicable Interventional Results available

Nursing Assistant Intervention to Prevent Delirium in Nursing Homes

NCT02994979
View directory record Official record
Conditions
Delirium
Interventions
Delirium-prevention, Sham comparator
Other
Lead sponsor
Jewish Home & Hospital Lifecare System
Other
Eligibility
18 Years and older
Enrollment
219 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Nov 4, 2019 · Synced Oct 21, 2026, 7:33 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Impact of Neuromonitoring During Cardiac Procedures

NCT02681731
View directory record Official record
Conditions
Delirium, Stroke, Acute Kidney Injury
Interventions
Not listed
Lead sponsor
Medtronic - MITG
Industry
Eligibility
18 Years to 100 Years
Enrollment
250,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 15, 2018 · Synced Oct 21, 2026, 7:33 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Reducing Delirium in the Surgical Intensive Care Unit

NCT02856737
View directory record Official record
Conditions
Delirium
Interventions
eye masks and earplugs
Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Oct 21, 2026, 7:33 PM EDT
Completed Not applicable Interventional

Effect of Sleep on the Recovery of Patients Admitted to the ICU

NCT04111900
View directory record Official record
Conditions
Critical Illness, Circadian Dysregulation, Delirium
Interventions
Sleep/Circadian Friendly
Behavioral
Lead sponsor
Rush University Medical Center
Other
Eligibility
18 Years to 99 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 18, 2023 · Synced Oct 21, 2026, 7:33 PM EDT
Not listed Phase 2 Interventional

Study to Determine if Pre- and Post- Operative TAP Catheters With Ropivacaine Versus Placebo Affects Anesthetic, Narcotic Dosing, and Pain Scores

NCT03149783
View directory record Official record
Conditions
Pain, Postoperative, Delirium, Anesthesia, Local
Interventions
Ropivacaine HCL, sodium chloride
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
50 Years and older
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2021
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 27, 2021 · Synced Oct 21, 2026, 7:33 PM EDT
Completed Not applicable Interventional Results available

Acupuncture for Sedation in the Intensive Care Unit (ICU)

NCT01362270
View directory record Official record
Conditions
Delirium, Respiratory Depression, Overmedication
Interventions
Verum Acupuncture, Sham Acupuncture
Device
Lead sponsor
Oregon Health and Science University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2015
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 20, 2020 · Synced Oct 21, 2026, 7:33 PM EDT
Recruiting Not applicable Interventional

Prefrontal Theta Burst Stimulation to Improve Cognitive Impairment After ICU Delirium

NCT07452939
View directory record Official record
Conditions
Post-delirium Cognitive Impairment
Interventions
Intermittent theta burst stimulation, Sham
Device
Lead sponsor
University of Florida
Other
Eligibility
50 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Oct 21, 2026, 7:33 PM EDT
Completed Not applicable Interventional

De-escalating Vital Sign Checks

NCT04046458
View directory record Official record
Conditions
Delirium, Sleep Disturbance
Interventions
Nighttime Vital Sign EHR Alert, No EHR alert
Behavioral · Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
Not listed
Enrollment
1,436 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 4, 2019 · Synced Oct 21, 2026, 7:33 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Healing Touch on Post Operative Pediatric Patients

NCT01738308
View directory record Official record
Conditions
Surgery, Stress, Pain, Children, Post-Traumatic Stress Disorder
Interventions
Healing Touch, Healing Touch Sham Treatment
Procedure
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
3 Years to 4 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 24, 2021 · Synced Oct 21, 2026, 7:33 PM EDT
Terminated No phase listed Observational

Ammonia Levels and Cognitive Impairment

NCT02059356
View directory record Official record
Conditions
Dementia, Cognitive Decline, Cognitive Impairment, Developmental Delay
Interventions
Not listed
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2014
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 17, 2015 · Synced Oct 21, 2026, 7:33 PM EDT