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ClinicalTrials.gov public records Last synced Oct 20, 2026, 1:03 PM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 25–48 of 322 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Confusion Clear all
Completed No phase listed Observational

Cholinesterase Activity and DeliriUm During Critical Illness Study

NCT03098472
View directory record Official record
Conditions
Delirium, Cognitive Impairment
Interventions
Not listed
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
279 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 11, 2022 · Synced Oct 20, 2026, 1:03 PM EDT
Completed No phase listed Observational

Enhancing Care Coordination: Hospital to Home for Cognitively Impaired Older Adults and Their Caregivers

NCT00294307
View directory record Official record
Conditions
Dementia, Dementia, Vascular, Alzheimer Disease, Delirium, Dementia, Amnestic, Cognitive Disorders, Lewy Body Disease, Mild Cognitive Impairment
Interventions
Augmented Standard Care (ASC), Resource Nurse Care (RNC), Advanced Practice Nurse Care (APNC)
Behavioral
Lead sponsor
University of Pennsylvania
Other
Eligibility
65 Years and older
Enrollment
814 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2012
U.S. locations
3
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 5, 2019 · Synced Oct 20, 2026, 1:03 PM EDT
Completed Not applicable Interventional

e-CHAMP: Enhancing Care for Hospitalized Older Adults With Memory Problems

NCT00182832
View directory record Official record
Conditions
Cognitive Impairment, Delirium
Interventions
e-CHAMP (Enhancing Care for Hospitalized Older Adults with Cognitive Impairment), Standard Care
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
65 Years and older
Enrollment
424 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 13, 2016 · Synced Oct 20, 2026, 1:03 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Reducing Delirium in the Surgical Intensive Care Unit

NCT02856737
View directory record Official record
Conditions
Delirium
Interventions
eye masks and earplugs
Other
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 11, 2017 · Synced Oct 20, 2026, 1:03 PM EDT
Terminated Phase 1 Interventional

How Your Patients' Non-REM Sleep Changes On Sedatives in the Intensive Care Units

NCT00826553
View directory record Official record
Conditions
Delirium, Respiratory Failure
Interventions
Dexmedetomidine, GABA agonist
Drug
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2013
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Jun 5, 2017 · Synced Oct 20, 2026, 1:03 PM EDT
Recruiting Not applicable Interventional

Short-term And Longer-term Cognitive Impact Of Neurochecks

NCT06219889
View directory record Official record
Conditions
Intracerebral Hemorrhage
Interventions
Frequency of neurochecks
Behavioral
Lead sponsor
University of California, San Diego
Other
Eligibility
18 Years to 100 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2025 · Synced Oct 20, 2026, 1:03 PM EDT
Completed No phase listed Observational

Postoperative Delirium: EEG Markers of Sleep and Wakefulness

NCT03291626
View directory record Official record
Conditions
Postoperative Delirium
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
60 Years and older
Enrollment
234 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 13, 2025 · Synced Oct 20, 2026, 1:03 PM EDT
Recruiting No phase listed Observational

Pervasive Sensing and AI in Intelligent ICU

NCT05127265
View directory record Official record
Conditions
Critical Illness, Pain, Delirium, Confusion
Interventions
Video Monitoring, Accelerometer Monitoring, Noise Level Monitoring, Light Level Monitoring, Air Quality Monitoring, EKG Monitoring, Vitals Monitoring, Biosample Collection, Delirium Motor Subtyping Scale 4 (DMSS-4)
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Oct 20, 2026, 1:03 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Using Virtual Reality to Improve Medical Training

NCT07542834
View directory record Official record
Conditions
Type 2 Diabetes (T2DM), Geriatric Syndromes, Disability Hearing, Disability Physical, Urinary Tract Infection(UTI), Delirium Confusional State
Interventions
Cinematic Virtual Reality Training, Traditional Didactic Lecture
Behavioral
Lead sponsor
Ohio University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Oct 20, 2026, 1:03 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

A D1 Agonist For Working Memory

NCT02507206
View directory record Official record
Conditions
Schizotypal Personality Disorder, SPD
Interventions
DAR 0-100A, Placebo
Drug
Lead sponsor
Antonia New
Other
Eligibility
18 Years to 65 Years
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2018
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 9, 2018 · Synced Oct 20, 2026, 1:03 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Sight and Hearing Investigation Into Effects on Delirium

NCT06176625
View directory record Official record
Conditions
Hearing Loss, Hearing Loss, Age-Related, Hearing Disability, Delirium, Delirium in Old Age, Delirium of Mixed Origin, Delirium With Dementia, Delirium on Emergence, Delirium, Cause Unknown, Delirium Superimposed on Dementia, Delirium Confusional State, Delirium;Non Alcoholic, Hearing Loss, Bilateral, Hearing Loss, Sensorineural, Hearing Loss, Functional, Hearing Loss, High-Frequency, Hearing
Interventions
Communication Signage, Amplifier Use
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
65 Years and older
Enrollment
1,543 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Oct 20, 2026, 1:03 PM EDT
Completed Not applicable Interventional

Acupuncture for the Prevention of Emergence Delirium in Children Undergoing Myringotomy Tube Placement

NCT02383004
View directory record Official record
Conditions
Delirium, Psychomotor Agitation
Interventions
Acupuncture
Other
Lead sponsor
Oregon Health and Science University
Other
Eligibility
1 Year to 6 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Jan 18, 2017 · Synced Oct 20, 2026, 1:03 PM EDT
Completed No phase listed Observational

Delirium in Persons With Dementia

NCT01394328
View directory record Official record
Conditions
Delirium Superimposed on Dementia
Interventions
Not listed
Lead sponsor
Penn State University
Other
Eligibility
65 Years and older
Enrollment
308 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
State College, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 16, 2018 · Synced Oct 20, 2026, 1:03 PM EDT
Terminated Phase 4 Interventional Results available

Adjunct Methadone to Decrease the Duration of Mechanical Ventilation in the Medical Intensive Care Unit

NCT02025855
View directory record Official record
Conditions
Opioid Use, Unspecified With Withdrawal, Opioid-Induced Disorders, Delirium
Interventions
Methadone, Placebo
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years and older
Enrollment
9 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 5, 2025 · Synced Oct 20, 2026, 1:03 PM EDT
Active, not recruiting Not applicable Interventional

PICU Up!: A Pilot Stepped-wedge Trial of a Multicomponent Early Mobility Intervention for Critically Ill Children

NCT03860168
View directory record Official record
Conditions
Critical Illness
Interventions
PICU Up!
Other
Lead sponsor
Johns Hopkins University
Other
Eligibility
0 Years to 24 Years
Enrollment
2,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 28, 2026 · Synced Oct 20, 2026, 1:03 PM EDT
Recruiting Not applicable Interventional

VR-Based Cognitive Stimulation Games for Delirium Prevention

NCT07641153
View directory record Official record
Conditions
Surgery, Delirium - Postoperative, Delirium
Interventions
Virtual Reality Software, Virtual Reality movies, Nurse led control arm
Other
Lead sponsor
The Methodist Hospital Research Institute
Other
Eligibility
Up to 65 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
2
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Oct 20, 2026, 1:03 PM EDT
Active, not recruiting Phase 2Phase 3 Interventional

Haloperidol and Lorazepam in Controlling Symptoms of Persistent Agitated Delirium in Patients With Advanced Cancer Undergoing Palliative Care

NCT03743649
View directory record Official record
Conditions
Delirium, Locally Advanced Malignant Neoplasm, Metastatic Malignant Neoplasm, Recurrent Malignant Neoplasm
Interventions
Haloperidol, Lorazepam, Placebo, Quality-of-Life Assessment, Questionnaire Administration
Drug · Other
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
2
States / cities
Houston, Texas • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Oct 20, 2026, 1:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effects of Healing Touch on Post Operative Pediatric Patients

NCT01738308
View directory record Official record
Conditions
Surgery, Stress, Pain, Children, Post-Traumatic Stress Disorder
Interventions
Healing Touch, Healing Touch Sham Treatment
Procedure
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
3 Years to 4 Years
Enrollment
240 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2017
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 24, 2021 · Synced Oct 20, 2026, 1:03 PM EDT
Completed Phase 2 Interventional Results available

TXA in Spinal Fusion

NCT04272606
View directory record Official record
Conditions
Degenerative Disc Disease
Interventions
Tranexamic Acid, Saline Solution, Visual Acuity Exam, 3 Minute Diagnostic Interview for Confusion Assessment Method (3D-CAM)
Drug · Diagnostic Test
Lead sponsor
Catherine R. Olinger
Other
Eligibility
18 Years to 90 Years
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 12, 2024 · Synced Oct 20, 2026, 1:03 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Monochromatic Light on Incidence of Emergence Delirium in Children

NCT03285243
View directory record Official record
Conditions
Emergence Delirium, Anesthesia Emergence Delirium
Interventions
Monochromatic blue light
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
2 Years to 6 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 29, 2024 · Synced Oct 20, 2026, 1:03 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

EEG-Guided Analgesic Titration During General Anesthesia to Improve Early Neurocognitive Recovery in Older Patients

NCT04443517
View directory record Official record
Conditions
Postoperative Delirium
Interventions
Alpha Optimization, Emergence from anesthesia with Dexmedetomidine
Procedure · Behavioral
Lead sponsor
Columbia University
Other
Eligibility
60 Years and older
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 20, 2026, 1:03 PM EDT
Completed Not applicable Interventional Results available

Perioperative Multimodal General AnesTHesia Focusing on Specific CNS Targets in Patients Undergoing carDiac surgERies

NCT05279898
View directory record Official record
Conditions
Postoperative Delirium, Hemodynamic Instability, Pain, Neurocognitive Dysfunction
Interventions
EEG Monitoring, Ropivacaine, Ketamine, Remifentanil, Dexmedetomidine, Rocuronium, Propofol
Device · Drug
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
60 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 26, 2025 · Synced Oct 20, 2026, 1:03 PM EDT
Completed Early Phase 1 Interventional

The PATHFINDER Study: A Feasibility Trial

NCT04016740
View directory record Official record
Conditions
Coronary Artery Disease, Delirium
Interventions
Ropivacaine, Ketamine, Remifentanil, Dexmedetomidine, Rocuronium, Propofol, Sevoflurane, EEG monitoring
Drug · Device
Lead sponsor
Beth Israel Deaconess Medical Center
Other
Eligibility
60 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 28, 2021 · Synced Oct 20, 2026, 1:03 PM EDT
Active, not recruiting Not applicable Interventional

CTSN Embolic Protection Trial

NCT06027788
View directory record Official record
Conditions
Delirium, Ischemic Stroke, Acute Kidney Injury, Heart Valve Disease, Coronary Artery Disease
Interventions
CardioGard Embolic Protection Cannula, Standard Aortic Cannula
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
60 Years and older
Enrollment
842 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
20
States / cities
North Little Rock, Arkansas • Los Angeles, California • Atlanta, Georgia + 16 more
Source: ClinicalTrials.gov public record
Updated Oct 2, 2026 · Synced Oct 20, 2026, 1:03 PM EDT