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ClinicalTrials.gov public records Last synced Oct 21, 2026, 4:02 AM EDT

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Showing 121–144 of 322 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Confusion Clear all
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility and Acceptability of Using Weighted Blankets to Prevent and /or Mitigate Delirium

NCT06161480
View directory record Official record
Conditions
Delirium
Interventions
Weighted Blanket
Device
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
18 Years and older
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Feb 24, 2026 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional Results available

Recommendations and Alerting for Delirium Alleviation in Real-Time (RADAR)

NCT04007523
View directory record Official record
Conditions
Delirium
Interventions
Family Support System, HELP Support System
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
70 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Phase 4 Interventional

Donepezil in the Prevention of Post-Operative Cognitive Decline

NCT00182845
View directory record Official record
Conditions
Postoperative Complications, Delirium
Interventions
Donepezil
Drug
Lead sponsor
Pfizer
Industry
Eligibility
65 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Oct 21, 2026, 4:02 AM EDT
Completed No phase listed Observational

The Impact of Cytochrome P450 Abnormalities in Patients With Delirium.

NCT03829670
View directory record Official record
Conditions
Delirium, Cytochrome P-450 Enzyme System
Interventions
Cytochrome P450 test
Diagnostic Test
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 99 Years
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Park Ridge, Illinois
Source: ClinicalTrials.gov public record
Updated Oct 4, 2024 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional

Massage Technique for Pain, Anxiety and Delirium in SAH Patients

NCT01982656
View directory record Official record
Conditions
Subarachnoid Hemorrhage, Anxiety, Pain, Delirium, Sleep
Interventions
Massage
Other
Lead sponsor
Sara E. Hocker, M.D
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 23, 2018 · Synced Oct 21, 2026, 4:02 AM EDT
Terminated Phase 4 Interventional Results available

Flumazenil for Hypoactive Delirium Secondary to Benzodiazepine Exposure

NCT02899156
View directory record Official record
Conditions
Hypoactive Delirium
Interventions
Flumazenil, Placebo
Drug
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Sacramento, California
Source: ClinicalTrials.gov public record
Updated Jul 23, 2020 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Phase 2 Interventional

A Single Site, Randomized, Double-blind, Placebo Controlled Trial of NIC5-15 in Subjects With Alzheimer's Disease

NCT01928420
View directory record Official record
Conditions
Alzheimer's Disease, Dementia
Interventions
Drug: NIC5-15, Placebo
Drug
Lead sponsor
Humanetics Corporation
Industry
Eligibility
40 Years to 95 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2014
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Oct 17, 2016 · Synced Oct 21, 2026, 4:02 AM EDT
Not listed No phase listed Observational

Driving Rehabilitation and Innovation for Evaluating Risk in Post-Intensive Care Unit Survivors

NCT05999903
View directory record Official record
Conditions
Delirium, Critical Illness, Drive
Interventions
Not listed
Lead sponsor
Baylor Research Institute
Other
Eligibility
40 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Temple, Texas
Source: ClinicalTrials.gov public record
Updated Feb 6, 2025 · Synced Oct 21, 2026, 4:02 AM EDT
Active, not recruiting Not applicable Interventional

Nutritional Therapy for Delirium in Elderly Hospitalized Subjects

NCT05066503
View directory record Official record
Conditions
Subacute Delirium
Interventions
260279 active study product
Dietary Supplement
Lead sponsor
University of Arkansas
Other
Eligibility
60 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2027
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Oct 21, 2026, 4:02 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Interventions for Postoperative Delirium: Biomarker-2 (IPOD-B2)

NCT02926417
View directory record Official record
Conditions
Delirium
Interventions
High Density-Electroencephalogram
Procedure
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Nov 1, 2021 · Synced Oct 21, 2026, 4:02 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Stanford PIPRA Validation Study in an Elderly Orthopedic Population

NCT06567574
View directory record Official record
Conditions
Delirium, Postoperative Delirium, Cognitive Impairment
Interventions
Not listed
Lead sponsor
Stanford University
Other
Eligibility
65 Years and older
Enrollment
250 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Oct 21, 2026, 4:02 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Positive Imagery Therapy and the Incidence of Emergence Reactions With the Use of Ketamine

NCT04746079
View directory record Official record
Conditions
Procedural Sedation, Emergence Delirium
Interventions
Positive Imagery Therapy
Behavioral
Lead sponsor
Mercy Health Ohio
Other
Eligibility
18 Years and older
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Youngstown, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 23, 2022 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Perioperative Cognitive Protection - Cognitive Exercise and Cognitive Reserve (The Neurobics Trial)

NCT02230605
View directory record Official record
Conditions
Delirium
Interventions
Mini-Mental State Examination, Self-Administered Gerocognitive Examination, Geriatric Depression Scale, Charlson Comorbidity Index, Short Form 36 Health Survey, Confusion Assessment Method, Memorial Delirium Assessment Scale, Postoperative Quality of Recovery Scale
Other
Lead sponsor
Ohio State University
Other
Eligibility
60 Years and older
Enrollment
322 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 11, 2019 · Synced Oct 21, 2026, 4:02 AM EDT
Withdrawn No phase listed Observational

Assessment of Delirium in Hospitalized Patients

NCT02258386
View directory record Official record
Conditions
Delirium
Interventions
Not listed
Lead sponsor
University of Arizona
Other
Eligibility
70 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Aug 22, 2024 · Synced Oct 21, 2026, 4:02 AM EDT
Terminated Phase 4 Interventional

Namenda to Prevent Post-Operative Delirium

NCT00303433
View directory record Official record
Conditions
Delirium, Post-Operative States
Interventions
Namenda
Drug
Lead sponsor
University of Rochester
Other
Eligibility
50 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jun 3, 2015 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Phase 4 Interventional Results available

Propofol in Emergence Agitation

NCT00535613
View directory record Official record
Conditions
Emergence Agitation
Interventions
Propofol
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
12 Months to 6 Years
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 21, 2019 · Synced Oct 21, 2026, 4:02 AM EDT
Withdrawn No phase listed Observational Accepts healthy volunteers

Determinants of Implementation Success Coordinating Ventilator, Early Ambulation and Rehabilitation Efforts

NCT04249141
View directory record Official record
Conditions
Implementation Science, Delirium, Intensive Care Unit Acquired Weakness, Pain, Sedation Complication, Mechanical Ventilation Complication
Interventions
Survey and concept mapping
Other
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 100 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 16, 2023 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional Results available

Pharmacological Management of Delirium

NCT00842608
View directory record Official record
Conditions
Delirium, Cognitive Impairment
Interventions
Reduced exposure to anticholinergics, Reduced exposure to benzodiazepines, Haloperidol, Usual care
Behavioral · Procedure · Drug
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
551 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
3
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 17, 2018 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

High Confusion: Cannabis & Driving

NCT06236815
View directory record Official record
Conditions
Impairment, Cognitive, Impairment of Attention, Impairment, Psychomotor
Interventions
Delta-9-THC, Delta-8-THC, Placebo
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 49 Years
Enrollment
5 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Oct 10, 2025 · Synced Oct 21, 2026, 4:02 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Improve the Patients' Recovery With Family- Caregivers to End Delirium

NCT05118867
View directory record Official record
Conditions
Delirium
Interventions
iPREPARED
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
60 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Phase 3 Interventional Results available

Clinical Trial of Gabapentin to Decrease Postoperative Delirium and Pain

NCT00221338
View directory record Official record
Conditions
Postoperative Delirium, Postoperative Pain, Opioid Use, Hospital Length of Stay
Interventions
Gabapentin
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
65 Years and older
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2014
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 10, 2020 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

A Clinical Trial of Intravenous Lidocaine After Spinal Surgery to Prevent Delirium and Reduce Pain

NCT05010148
View directory record Official record
Conditions
Postoperative Delirium, Postoperative Pain, Spinal Fusion
Interventions
Lidocaine IV, Placebo
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
60 Years and older
Enrollment
219 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Sep 17, 2026 · Synced Oct 21, 2026, 4:02 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Trajectory of Recovery in the Elderly

NCT02275026
View directory record Official record
Conditions
Delayed Emergence From Anesthesia, Postoperative Delirium, Postoperative Cognitive Dysfunction
Interventions
Functional magnetic resonance imaging
Procedure
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
40 Years to 80 Years
Enrollment
104 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2020
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 15, 2021 · Synced Oct 21, 2026, 4:02 AM EDT
Withdrawn Not applicable Interventional

Simulated Walking With Multiplexing Prism for Field Expansion in Monocular Vision

NCT06024668
View directory record Official record
Conditions
One Eye Blindness, Blind Left Eye, Blind Right Eye
Interventions
Multiplexing Prism
Device
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
16 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 21, 2026, 4:02 AM EDT