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ClinicalTrials.gov public records Last synced Oct 21, 2026, 11:14 PM EDT

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Showing 121–144 of 272 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Consciousness Clear all
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Lazanda Fentanyl Nasal Spray Pre Radiofrequency Nerve Ablations(RFA) of Lumbar Facet Joints

NCT02571634
View directory record Official record
Conditions
Minor Procedural Pain
Interventions
Lazanda
Drug
Lead sponsor
Defense and Veterans Center for Integrative Pain Management
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Fort Bragg, North Carolina
Source: ClinicalTrials.gov public record
Updated Oct 25, 2016 · Synced Oct 21, 2026, 11:14 PM EDT
Completed Not applicable Interventional Results available

Effectiveness of Atropine and Glycopyrrolate to Reduce Hyper Salivation With Ketamine Sedation

NCT01191398
View directory record Official record
Conditions
Sialorrhea
Interventions
Atropine (0.01mg/kg), Glycopyrrolate (0.01mg/kg), Normal saline 0.9%
Drug
Lead sponsor
Craig J. Huang
Other
Eligibility
6 Months to 18 Years
Enrollment
52 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Apr 16, 2014 · Synced Oct 21, 2026, 11:14 PM EDT
Recruiting No phase listed Observational

Rapid-Response EEG in Children With Suspected Status Epilepticus

NCT06564662
View directory record Official record
Conditions
Status Epilepticus, Coma
Interventions
Rapid Response EEG
Device
Lead sponsor
Children's Hospital at Montefiore
Other
Eligibility
2 Years to 18 Years
Enrollment
60 participants
Timeline
2021 – 2026
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Oct 21, 2026, 11:14 PM EDT
Completed No phase listed Observational

Endobronchial Ultrasound Guided Transbronchial Needle Aspiration Performed Under General Anesthesia Versus Moderate Sedation

NCT01430962
View directory record Official record
Conditions
Mediastinal Lymphadenopathies, Mediastinal Masses, Hilar Lymphadenopathies
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years and older
Enrollment
149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 23, 2015 · Synced Oct 21, 2026, 11:14 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

PET Scan in Patients With Neurocardiologic Disorders

NCT00001418
View directory record Official record
Conditions
Autonomic Nervous System Diseases
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
335 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
1994 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 21, 2026, 11:14 PM EDT
Not listed Not applicable Interventional

Consciousness-based Ayurveda Lifestyle Program for Improving Quality of Life in Survivors of Breast Cancer

NCT05743023
View directory record Official record
Conditions
Breast Cancer Survivors
Interventions
Ayurvedic lifestyle protocol
Behavioral
Lead sponsor
Robert Schneider, MD
Other
Eligibility
18 Years and older · Female only
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Richmond, California
Source: ClinicalTrials.gov public record
Updated Feb 24, 2023 · Synced Oct 21, 2026, 11:14 PM EDT
Not yet recruiting Not applicable Interventional

The Coma Family Program (COMA-F): A Resilience Program for Caregivers of Patients With Severe Acute Brain Injury

NCT07331324
View directory record Official record
Conditions
Caregiver Distress, Emotional Distress, Caregivers, Resilience, Coma, Brain Injury
Interventions
Coma Family Program 1, Coma Family Program 2
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
3
States / cities
Baltimore, Maryland • Boston, Massachusetts • Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Feb 20, 2026 · Synced Oct 21, 2026, 11:14 PM EDT
Completed Not applicable Interventional

The Use of LIFUP in Chronic Disorders of Consciousness

NCT04921683
View directory record Official record
Conditions
Disorder of Consciousness, Vegetative State, Minimally Conscious State, Minimally Conscious State Plus, Minimally Conscious State Minus, Traumatic Brain Injury, CVA (Cerebrovascular Accident), Anoxia, Brain, Thalamic Infarction, Coma; Prolonged
Interventions
BX Pulsar 1002 (LIFUP) Low intensity Focused Ultrasound Pulsation
Device
Lead sponsor
Casa Colina Hospital and Centers for Healthcare
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Pomona, California
Source: ClinicalTrials.gov public record
Updated May 6, 2023 · Synced Oct 21, 2026, 11:14 PM EDT
Completed Phase 4 Interventional Results available

Trial of Levomilnacipran in Geriatric Depression

NCT02466958
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
levomilnacipran, Placebo
Drug
Lead sponsor
University of California, Los Angeles
Other
Eligibility
60 Years and older
Enrollment
29 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 14, 2019 · Synced Oct 21, 2026, 11:14 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Effectiveness of Amantadine Hydrochloride for Treatment of Severe Traumatic Brain Injury (TBI)

NCT00970944
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Amantadine Hydrochloride, Placebo
Drug
Lead sponsor
JFK Medical Center
Other
Eligibility
16 Years to 65 Years
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2010
U.S. locations
8
States / cities
Braintree, Massachusetts • Jackson, Mississippi • New York, New York + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 24, 2012 · Synced Oct 21, 2026, 11:14 PM EDT
Completed Phase 4 Interventional

Propranolol to Treat Fainting Due to Sympathoadrenal Imbalance

NCT00060866
View directory record Official record
Conditions
Neurocardiogenic Syncope
Interventions
Propranolol
Drug
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 21, 2026, 11:14 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Use of Ketamine for Conscious Sedation in Flexible Bronchoscopy

NCT06181188
View directory record Official record
Conditions
Conscious Sedation, Patient Satisfaction, Ketamine
Interventions
Ketamine, Midazolam, Fentanyl
Drug
Lead sponsor
Brooke Army Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Dec 26, 2023 · Synced Oct 21, 2026, 11:14 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Brain-to-brain Synchrony in Ss With Different Levels of Social Interaction

NCT06673589
View directory record Official record
Conditions
Social Dynamics
Interventions
Transcendental Meditation
Behavioral
Lead sponsor
Maharishi International University
Other
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Fairfield, Iowa
Source: ClinicalTrials.gov public record
Updated Nov 15, 2024 · Synced Oct 21, 2026, 11:14 PM EDT
Completed Not applicable Interventional Results available

Brain Connectivity and Response to Tai Chi in Geriatric Depression

NCT02460666
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Tai-Chi-Chih (TCC), Health Education and Wellness Classes (HEW)
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
60 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 16, 2021 · Synced Oct 21, 2026, 11:14 PM EDT
Completed Phase 3 Interventional

Open-Label Treatment With Duloxetine Hydrochloride Once-Daily Dosing for Evaluation of Stabilization Dose in Patients With Major Depression

NCT00042562
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
duloxetine
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2003
U.S. locations
23
States / cities
Carlsbad, California • Los Angeles, California • Stanford, California + 20 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2006 · Synced Oct 21, 2026, 11:14 PM EDT
Completed No phase listed Observational

Incidence and Nature of Respiratory Impairment in Consecutive Patients Undergoing Bronchoscopy Under Conscious Sedation: A Pilot Study

NCT03886454
View directory record Official record
Conditions
Conscious Sedation, Bronchoscopy
Interventions
Not listed
Lead sponsor
Tufts Medical Center
Other
Eligibility
18 Years and older
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Aug 28, 2019 · Synced Oct 21, 2026, 11:14 PM EDT
Enrolling by invitation Phase 2 Interventional Accepts healthy volunteers

Assessing Covert Consciousness During Dexmedetomidine and Ketamine Sedation: An fMRI Study

NCT07705022
View directory record Official record
Conditions
Healthy, Covert Consciousness
Interventions
Dexmedetomidine (+propofol as indicated), Ketamine
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 40 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Aug 11, 2026 · Synced Oct 21, 2026, 11:14 PM EDT
Completed Phase 2 Interventional

Non-Pharmacologic Therapy for Neurocardiogenic Syncope

NCT00096902
View directory record Official record
Conditions
Syncope
Interventions
Tilt table test
Procedure
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 21, 2026, 11:14 PM EDT
Completed No phase listed Observational

EEG Characteristics in Youth POTS and/or Syncope

NCT02167412
View directory record Official record
Conditions
Syncope, Postural Tachycardia Syndrome, Orthostatic Intolerance
Interventions
Not listed
Lead sponsor
Nationwide Children's Hospital
Other
Eligibility
9 Years to 21 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 27, 2018 · Synced Oct 21, 2026, 11:14 PM EDT
Active, not recruiting No phase listed Observational

Aveir VR Real-World Evidence Post-Approval Study

NCT05270499
View directory record Official record
Conditions
Cardiac Pacemaker, Arrythmia, Bradycardia
Interventions
Aveir VR Leadless Pacemaker System
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
3,427 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2034
U.S. locations
1
States / cities
Sylmar, California
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 21, 2026, 11:14 PM EDT
Recruiting No phase listed Observational

Recovery Trajectory for Coma and Disorders of Consciousness

NCT07614074
View directory record Official record
Conditions
Coma, Disorders of Consciousness, Cardiac Arrest (CA), Traumatic Brain Injuries, Ischemic Stroke, Hemorrhagic Stroke, Intracerebral, Meningitis/Encephalitis, Status Epilepticus
Interventions
Not listed
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2033
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Oct 21, 2026, 11:14 PM EDT
Terminated Not applicable Interventional Results available

Thalamic Low Intensity Focused Ultrasound in Brain Injury

NCT02522429
View directory record Official record
Conditions
Consciousness Disorders, Brain Injuries
Interventions
Low Intensity Focused Ultrasound Device
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 28, 2022 · Synced Oct 21, 2026, 11:14 PM EDT
Completed Not applicable Interventional

Randomized Study of Midodrine, an Alpha Adrenergic Agonist, in Patients With Neurally Mediated Syncope

NCT00004479
View directory record Official record
Conditions
Syncope
Interventions
midodrine
Drug
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
16 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 1999
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 24, 2005 · Synced Oct 21, 2026, 11:14 PM EDT
Not yet recruiting No phase listed Observational

Walking With Overground Robotic Exoskeleton Device to Increase Behavioral Responsiveness in Patients With Disorders of Consciousness (WALK DOC)

NCT07709559
View directory record Official record
Conditions
Disorders of Consciousness Due to Severe Brain Injury, Disorders of Consciousness
Interventions
Overground Robotic Exoskeleton (ORE)
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 21, 2026 · Synced Oct 21, 2026, 11:14 PM EDT