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ClinicalTrials.gov public records Last synced Oct 21, 2026, 6:06 PM EDT

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Showing 169–192 of 230 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Consciousness Disorders Clear all
Completed Phase 1Phase 2 Interventional Results available

A Randomized Double Blinded Study to Examine the Use of N-acetyl Cysteine for the Prevention and Treatment of HAAF in Patients With Type 1 Diabetes

NCT02206152
View directory record Official record
Conditions
Type 1 Diabetes, Hypoglycemia Unawareness
Interventions
N-acetyl cysteine, Placebo
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 65 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 31, 2020 · Synced Oct 21, 2026, 6:06 PM EDT
Completed Phase 1 Interventional

Smoking Cessation for Depression and Anxiety Treatment

NCT02002858
View directory record Official record
Conditions
Smoking, Anxiety Disorders, Depression Disorders
Interventions
Nicotine Patch, Depression and Anxiety Smoking Cessation Treatment, Educational-Support Psychotherapy
Drug · Behavioral
Lead sponsor
University of Houston
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 7, 2017 · Synced Oct 21, 2026, 6:06 PM EDT
Completed Not applicable Interventional

PREPARE - Primary Prevention Parameters Evaluation

NCT00279279
View directory record Official record
Conditions
Tachycardia, Ventricular, Implantable Cardioverter Defibrillator (ICD), Fibrillation, Ventricular, Syncope
Interventions
Implanted Device
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
700 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2006
U.S. locations
31
States / cities
Birmingham, Alabama • Mesa, Arizona • Phoenix, Arizona + 28 more
Source: ClinicalTrials.gov public record
Updated Oct 26, 2006 · Synced Oct 21, 2026, 6:06 PM EDT
Recruiting Phase 2 Interventional

Prophylactic Anti-Seizure Medication vs No Anti-Seizure Medication for Patients With Primary Motor Cortex Brain Metastases

NCT07130786
View directory record Official record
Conditions
Seizures, Primary Motor Cortex, Brain Metastases From Non-small Cell Lung Cancer (NSCLC), Brain Metastases, Adult, Brain Metastases From Extra-cranial Solid Tumors
Interventions
Levetiracetam (Keppra)
Drug
Lead sponsor
Ayal A. Aizer, MD
Other
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 8, 2026 · Synced Oct 21, 2026, 6:06 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers

Dose Escalation, Double-Blind Treatment With Duloxetine Hydrochloride Once Daily Dosing for Evaluation of Safety in Major Depression

NCT00042575
View directory record Official record
Conditions
Major Depressive Disorder
Interventions
Duloxetine
Drug
Lead sponsor
Eli Lilly and Company
Industry
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002
U.S. locations
9
States / cities
Trumbull, Connecticut • Lafayette, Indiana • Gaithersburg, Maryland + 6 more
Source: ClinicalTrials.gov public record
Updated Jul 19, 2006 · Synced Oct 21, 2026, 6:06 PM EDT
Completed No phase listed Observational

A Safety and Efficacy of Pomalyst® Capsules Under the Actual Use in All Patients Who Are Treated With Pomalyst at a Dose of 1 mg, 2 mg, 3 mg, or 4 mg

NCT02921828
View directory record Official record
Conditions
Multiple Myeloma
Interventions
Not listed
Lead sponsor
Celgene
Industry
Eligibility
18 Years and older
Enrollment
1,149 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015
U.S. locations
1
States / cities
No City Provided, New Jersey
Source: ClinicalTrials.gov public record
Updated Jul 5, 2022 · Synced Oct 21, 2026, 6:06 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

UNderstanding CONSciousness Connectedness and Intraoperative Unresponsiveness Study

NCT03284307
View directory record Official record
Conditions
Unconsciousness, Consciousness
Interventions
Dexmedetomidine, Ketamine, Propofol, Midazolam
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
18 Years to 40 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Oct 21, 2026, 6:06 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Impact of Complimentary and Alternative Practices on Patient Wellbeing During Rehabilitation

NCT05082246
View directory record Official record
Conditions
Anxiety, Depression, Stress, Pain, Heart Rate, Blood Pressure
Interventions
Conscious Breathing, Heartfulness Meditation, Emotional Freedom Technique
Other
Lead sponsor
WellSpan Health
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
York, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 18, 2021 · Synced Oct 21, 2026, 6:06 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Pilot RECAP Study in Healthy Volunteers

NCT04842045
View directory record Official record
Conditions
Psychedelic Experiences, Amnesia
Interventions
Psilocybin and Midazolam
Drug
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
21 Years to 65 Years
Enrollment
8 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated May 19, 2023 · Synced Oct 21, 2026, 6:06 PM EDT
Completed Not applicable Interventional

Stimulation of the Thalamus for Arousal Restoral in Temporal Lobe Epilepsy

NCT04897776
View directory record Official record
Conditions
Epilepsy, Temporal Lobe
Interventions
Central Thalamic Stimulation, Hippocampal Stimulation
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 75 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
3
States / cities
New Haven, Connecticut • Rochester, Minnesota • Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Dec 26, 2025 · Synced Oct 21, 2026, 6:06 PM EDT
Not yet recruiting Not applicable Interventional

An Interrupted Time-Series Pilot Trial of LGBTQ-Affirming Cognitive Processing Therapy for Interpersonal and Developmental Trauma

NCT07863817
View directory record Official record
Conditions
Post-Traumatic Stress Disorder, Chronic, Depressed Mood, Depressive and Anxiety Disorders, Anxiety, Depression - Major Depressive Disorder
Interventions
Cognitive Processing Therapy
Behavioral
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 85 Years
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 15, 2026 · Synced Oct 21, 2026, 6:06 PM EDT
Completed No phase listed Observational Results available

Physiologic Pacing Registry

NCT03719040
View directory record Official record
Conditions
Bradycardia, Sinus Node Dysfunction, Heart Block, Syncope, Cardiomyopathies, Ventricular Tachycardia, Heart Failure
Interventions
Physiologic pacing device implant
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
870 participants
Timeline
2018 – 2021
U.S. locations
26
States / cities
Huntsville, Alabama • Burlingame, California • San Diego, California + 22 more
Source: ClinicalTrials.gov public record
Updated Aug 19, 2024 · Synced Oct 21, 2026, 6:06 PM EDT
Completed No phase listed Observational

Validation of the San Francisco Syncope Rule

NCT00300625
View directory record Official record
Conditions
Syncope, Near Syncope
Interventions
Application of the San Francisco Syncope Rule
Procedure
Lead sponsor
Albert Einstein College of Medicine
Other
Eligibility
21 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated May 15, 2018 · Synced Oct 21, 2026, 6:06 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Spatial Scene Recognition Memory in Epilepsy Surgery

NCT07580183
View directory record Official record
Conditions
Focal Epilepsy, Temporal Lobe Epilepsy, Medically Refractory Epilepsy, Memory Disorders, Epilepsy Comorbidities, Epilepsy Intractable, Epilepsy Surgery, Epilepsy, Temporal Lobe, Memory Deficits, Memory Disorder, Spatial, Memory Dysfunction, Spatial Perception
Interventions
Virtual Tour Recognition Memory Task, Intracranial EEG Recording with Research Electrodes (Aim III only), MRI Neuroimaging and Neuropsychological Assessment (Aim I)
Behavioral · Device · Diagnostic Test
Lead sponsor
University of California, Davis
Other
Eligibility
18 Years to 55 Years
Enrollment
620 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2030
U.S. locations
2
States / cities
Sacramento, California • Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 12, 2026 · Synced Oct 21, 2026, 6:06 PM EDT
Completed Phase 4 Interventional Results available

Clinical Trial for the Prevention of Vasovagal Syncope

NCT00118482
View directory record Official record
Conditions
Syncope, Vasovagal, Neurally-Mediated
Interventions
fludrocortisone acetate
Drug
Lead sponsor
University of Calgary
Other
Eligibility
14 Years and older
Enrollment
213 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2011
U.S. locations
3
States / cities
Boston, Massachusetts • Nashville, Tennessee • Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 15, 2019 · Synced Oct 21, 2026, 6:06 PM EDT
Recruiting No phase listed Observational

Neuroprognostication Bias: A Collaboration to Reduce the Impact of Self-fulfilling Prophecy in Cardiac ARrEst

NCT03261089
View directory record Official record
Conditions
Cardiac Arrest
Interventions
Not listed
Lead sponsor
Boston Medical Center
Other
Eligibility
18 Years to 89 Years
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2027
U.S. locations
5
States / cities
San Francisco, California • New Haven, Connecticut • Gainesville, Florida + 2 more
Source: ClinicalTrials.gov public record
Updated Dec 24, 2025 · Synced Oct 21, 2026, 6:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Feasibility of mindBEAGLE in Disorders of Consciousness or Locked-In Syndrome

NCT02772302
View directory record Official record
Conditions
Consciousness Disorders, Locked-In Syndrome
Interventions
mindBEAGLE EEG-based brain-computer interface
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 3, 2021 · Synced Oct 21, 2026, 6:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Reconstructing Consciousness and Cognition

NCT01911195
View directory record Official record
Conditions
Postoperative Cognitive Dysfunction
Interventions
ISOFLURANE- Experimental Arm, Control Group: Cognitive Testing
Drug · Other
Lead sponsor
University of Michigan
Other
Eligibility
20 Years to 40 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2015
U.S. locations
3
States / cities
Ann Arbor, Michigan • St Louis, Missouri • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 20, 2024 · Synced Oct 21, 2026, 6:06 PM EDT
Completed Phase 2 Interventional Results available

mTBI Mechanisms of Action of HBO2 for Persistent Post-Concussive Symptoms

NCT01611194
View directory record Official record
Conditions
Traumatic Brain Injury With Brief Loss of Consciousness, Post-Concussion Syndrome
Interventions
Hyperbaric oxygen (HBO2) at 1.5 atms, Sham control 1.2 atms
Drug
Lead sponsor
U.S. Army Medical Research and Development Command
Federal
Eligibility
18 Years to 65 Years
Enrollment
71 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
5
States / cities
Colorado Springs, Colorado • Fort Carson, Colorado • Jacksonville, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Nov 21, 2018 · Synced Oct 21, 2026, 6:06 PM EDT
Completed No phase listed Observational

The U.K. Embryologist Fatigue Study

NCT05708963
View directory record Official record
Conditions
Fatigue, Stress, Burnout, Professional, Musculoskeletal Pain, Back Pain, Neck Pain, Headache, Dizziness, Sleep Disturbance, Chest Pain, Syncope, Cardiovascular Diseases, Shortness of Breath, Gastrointestinal Diseases
Interventions
Not listed
Lead sponsor
TMRW Life Sciences
Industry
Eligibility
22 Years to 65 Years
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 8, 2023 · Synced Oct 21, 2026, 6:06 PM EDT
Terminated Phase 2 Interventional Results available

Use of Dexmedetomidine in Acute Stroke and Cerebral Vasospasm Interventions

NCT01845441
View directory record Official record
Conditions
Stroke, Brain Ischemia, Vasospasm, Intracranial, Hemorrhage, Intracranial
Interventions
Dexmedetomidine, Fentanyl, Midazolam
Drug
Lead sponsor
University Hospitals Cleveland Medical Center
Other
Eligibility
18 Years to 85 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Dec 28, 2022 · Synced Oct 21, 2026, 6:06 PM EDT
Completed Phase 3 Interventional

Lethargic Depression Study

NCT00064467
View directory record Official record
Conditions
Epilepsy, Major Depressive Disorder (MDD)
Interventions
Extended-release bupropion (HCl)
Drug
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
18 Years and older
Enrollment
268 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
24
States / cities
Beverly Hills, California • Sherman Oaks, California • Temecula, California + 21 more
Source: ClinicalTrials.gov public record
Updated May 30, 2017 · Synced Oct 21, 2026, 6:06 PM EDT
Completed Not applicable Interventional Results available

Treatment of Post-Traumatic Brain Injury (Post-TBI) Fatigue With Light Therapy

NCT01725750
View directory record Official record
Conditions
Traumatic Brain Injury, Fatigue
Interventions
Bright White Light (BWL), Dim Red Light (DRL)
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 7, 2019 · Synced Oct 21, 2026, 6:06 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Conscious Sedation Efficacy of the MKO Melt (Midazolam, Ketamine, Ondansetron)

NCT03653520
View directory record Official record
Conditions
Cataract
Interventions
Diazepam, Tramadol, Ondansetron, MKO melt
Drug
Lead sponsor
Avanti Anesthesia
Other
Eligibility
18 Years and older
Enrollment
651 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Aug 31, 2018 · Synced Oct 21, 2026, 6:06 PM EDT