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ClinicalTrials.gov public records Last synced Oct 22, 2026, 5:58 AM EDT

Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.

Showing 73–96 of 1,008 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Constriction Clear all
Terminated Not applicable Interventional

Dorsal vs. Ventral Buccal Graft Dorsal vs. Ventral Buccal Graft

NCT02551783
View directory record Official record
Conditions
Urethral Stricture
Interventions
Urethroplasty with buccal mucosa graft, Ventral Buccal
Procedure
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 85 Years · Male only
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2019
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 1, 2019 · Synced Oct 22, 2026, 5:58 AM EDT
Completed No phase listed Observational

Conduction Abnormalities With Severe Aortic Stenosis Before and After Transcatheter Aortic Valve Replacement

NCT03180073
View directory record Official record
Conditions
Bradycardia
Interventions
Ziopatch Pre discharge, Ziopatch at Discharge, Ziopatch at 2 months
Diagnostic Test
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years to 90 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 21, 2021 · Synced Oct 22, 2026, 5:58 AM EDT
Terminated Not applicable Interventional Results available

Lutonix or Inpact for tHE tReatment Of fEmeropopliteal Stenosis - Drug Coated Balloon

NCT02812966
View directory record Official record
Conditions
Peripheral Arterial Disease
Interventions
Lutonix, IN.PACT
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years and older
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
6
States / cities
Chicago, Illinois • Downers Grove, Illinois • Hazel Crest, Illinois + 3 more
Source: ClinicalTrials.gov public record
Updated Oct 8, 2024 · Synced Oct 22, 2026, 5:58 AM EDT
Completed No phase listed Observational

Neurological Outcome With Carotid Artery Stenting

NCT00597974
View directory record Official record
Conditions
Carotid Artery Disease, Carotid Artery Stenosis, Stroke, Transient Ischemic Attack
Interventions
Angioplasty, Stent, Neurological and neuropsychological evaluations, Angiography
Procedure · Device · Other
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
108 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 4, 2015 · Synced Oct 22, 2026, 5:58 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Sleep Apnea and Hypertrophic Cardiomyopathy (HCM)

NCT03327623
View directory record Official record
Conditions
Hypertrophic Cardiomyopathy
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
290 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2024
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Oct 22, 2026, 5:58 AM EDT
Recruiting Not applicable Interventional

Balloon Inflation Time for Esophageal Strictures (BITES): A Randomized Multi-Center Study

NCT07100379
View directory record Official record
Conditions
Esophageal Atresia With Tracheo-esophageal Fistula, Esophageal Atresia, Esophageal Strictures
Interventions
Endoscopic Balloon Dilation
Procedure
Lead sponsor
Boston Children's Hospital
Other
Eligibility
Up to 18 Years
Enrollment
128 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
2
States / cities
Boston, Massachusetts • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 30, 2026 · Synced Oct 22, 2026, 5:58 AM EDT
Completed No phase listed Observational

Fast Assessment of STenosis Severity- FASTII Study

NCT03791320
View directory record Official record
Conditions
Coronary Artery Disease
Interventions
Vessel Fractional Flow Reserve
Diagnostic Test
Lead sponsor
Erasmus Medical Center
Other
Eligibility
18 Years and older
Enrollment
330 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 24, 2020 · Synced Oct 22, 2026, 5:58 AM EDT
Recruiting Phase 3 Interventional

Paclitaxel Coated Balloon for the Treatment of Chronic bEnigN sTricture- Esophagus

NCT05561114
View directory record Official record
Conditions
Esophageal Stricture
Interventions
GIE Medical ProTractX3 TTS DCB, Control
Combination Product · Other
Lead sponsor
GIE Medical
Industry
Eligibility
22 Years and older
Enrollment
198 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2031
U.S. locations
34
States / cities
Birmingham, Alabama • Scottsdale, Arizona • Irvine, California + 29 more
Source: ClinicalTrials.gov public record
Updated Jun 25, 2025 · Synced Oct 22, 2026, 5:58 AM EDT
Recruiting Not applicable Interventional

Bicuspid Aortic Valve Replacement: Evaluation of Transcatheter Versus Surgery-Pilot Trial

NCT06817148
View directory record Official record
Conditions
Aortic Valve Stenosis, Bicuspid Aortic Valve
Interventions
transcatheter aortic valve replacement (TAVR), surgical aortic valve replacement (SAVR)
Procedure
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
50 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2037
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Feb 10, 2025 · Synced Oct 22, 2026, 5:58 AM EDT
Active, not recruiting Not applicable Interventional Results available

Growth Trial: Study of the Renata Minima Stent

NCT05086016
View directory record Official record
Conditions
Coarctation of the Aorta, Pulmonary Artery Stenosis
Interventions
Catheterized Stenting
Device
Lead sponsor
Renata Medical
Industry
Eligibility
Not listed
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2028
U.S. locations
7
States / cities
Los Angeles, California • Boston, Massachusetts • Cincinnati, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 25, 2025 · Synced Oct 22, 2026, 5:58 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Spine Patient Outcomes Registry for Biomet/EBI (Electro-Biology, Inc)

NCT00726284
View directory record Official record
Conditions
Degenerative Disc Disease, Spinal Stenosis
Interventions
Not listed
Lead sponsor
Zimmer Biomet
Industry
Eligibility
Not listed
Enrollment
651 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
5
States / cities
Little Rock, Arkansas • Orange City, Florida • Akron, Ohio + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 24, 2020 · Synced Oct 22, 2026, 5:58 AM EDT
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Age and Sex-Specific PREValence of AcqUirEd VALVular Heart DiseasE

NCT05357404
View directory record Official record
Conditions
Valvular Heart Disease
Interventions
Not listed
Lead sponsor
Cardiovascular Research Foundation, New York
Other
Eligibility
65 Years to 85 Years
Enrollment
2,870 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Walnut Creek, California
Source: ClinicalTrials.gov public record
Updated Feb 7, 2025 · Synced Oct 22, 2026, 5:58 AM EDT
Completed Phase 1 Interventional Results available

Hypertrophic Regression With N-Acetylcysteine in HCM

NCT01537926
View directory record Official record
Conditions
Hypertrophic Cardiomyopathy
Interventions
N-acetylcysteine, Placebo
Drug
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 2, 2021 · Synced Oct 22, 2026, 5:58 AM EDT
Terminated Not applicable Interventional Results available

Comparison of Cervical Laminectomy to Laminoplasty

NCT01324622
View directory record Official record
Conditions
Spinal Cord Diseases
Interventions
Laminoplasty, laminectomy
Device · Procedure
Lead sponsor
Synthes USA HQ, Inc.
Industry
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2010
U.S. locations
4
States / cities
Beverly Hills, California • New Haven, Connecticut • Kansas City, Missouri + 1 more
Source: ClinicalTrials.gov public record
Updated Dec 7, 2017 · Synced Oct 22, 2026, 5:58 AM EDT
Withdrawn Phase 2 Interventional

Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of MEK162 in Noonan Syndrome Hypertrophic Cardiomyopathy

NCT01556568
View directory record Official record
Conditions
Cardiomegaly
Interventions
MEK162
Drug
Lead sponsor
Array Biopharma, now a wholly owned subsidiary of Pfizer
Industry
Eligibility
18 Years to 65 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 6, 2020 · Synced Oct 22, 2026, 5:58 AM EDT
Recruiting No phase listed Observational

Effect of Mavacamten Treatment on Coronary Flow Reserve in oHCM

NCT06023186
View directory record Official record
Conditions
Obstructive Hypertrophic Cardiomyopathy
Interventions
mavacamten
Drug
Lead sponsor
Michael Ayers
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Charlottesville, Virginia
Source: ClinicalTrials.gov public record
Updated Nov 6, 2024 · Synced Oct 22, 2026, 5:58 AM EDT
Terminated Phase 4 Interventional Results available

Aortic Stenosis and PhosphodiEsterase Type 5 iNhibition (ASPEN): A Pilot Study

NCT01275339
View directory record Official record
Conditions
Aortic Stenosis, LV Remodeling, Hypertrophy
Interventions
Tadalafil, Placebo
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced Oct 22, 2026, 5:58 AM EDT
Completed No phase listed Observational

trūFreeze® Spray Cryotherapy Patient Registry

NCT01802203
View directory record Official record
Conditions
Barrett Esophagus, Esophageal Dysplasia, Esophageal Neoplasm, Esophageal Stenosis, Bronchial Neoplasm, Stenosis of Bronchus or Trachea
Interventions
truFreeze Spray Cryotherapy
Device
Lead sponsor
US Endoscopy Group Inc.
Industry
Eligibility
18 Years and older
Enrollment
275 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
16
States / cities
La Jolla, California • Denver, Colorado • Jacksonville, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Jul 25, 2022 · Synced Oct 22, 2026, 5:58 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Magnetic Resonance Imaging for Evaluating Kidney Function

NCT00006173
View directory record Official record
Conditions
Healthy, Renovascular Hypertension
Interventions
Not listed
Lead sponsor
National Institutes of Health Clinical Center (CC)
NIH
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2000 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 4, 2008 · Synced Oct 22, 2026, 5:58 AM EDT
Not listed No phase listed Observational

Retrospective, Multicenter Clinical Evaluation of Health Economic Drivers and Complications for Two Lumbar Fusion Procedures

NCT02171169
View directory record Official record
Conditions
Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease (DDD)
Interventions
Not listed
Lead sponsor
Baxano Surgical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
3
States / cities
Fullerton, California • Waterford, Michigan • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 3, 2014 · Synced Oct 22, 2026, 5:58 AM EDT
Completed Phase 1 Interventional

Safety of Ataciguat in Patients With Moderate Calcific Aortic Valve Stenosis

NCT02049203
View directory record Official record
Conditions
Aortic Valve Stenosis
Interventions
Ataciguat, Placebo
Drug
Lead sponsor
Jordan D. Miller, Ph.D.
Other
Eligibility
50 Years and older
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jul 7, 2016 · Synced Oct 22, 2026, 5:58 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Predictors of Decompressive Laminectomy Outcomes

NCT02215551
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Not listed
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 90 Years
Enrollment
239 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2023
U.S. locations
7
States / cities
Denver, Colorado • Decatur, Georgia • Ann Arbor, Michigan + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 12, 2023 · Synced Oct 22, 2026, 5:58 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

REFINE Study: A Study In a Novel Interspinous Fusion Device In Subjects With Low Back Pain

NCT05504499
View directory record Official record
Conditions
Lumbar Spinal Stenosis
Interventions
Interspinous Fusion
Device
Lead sponsor
Pacific Research Institute
Network
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2028
U.S. locations
10
States / cities
Santa Rosa, California • Jupiter, Florida • Slidell, Louisiana + 6 more
Source: ClinicalTrials.gov public record
Updated Aug 18, 2022 · Synced Oct 22, 2026, 5:58 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Impact of Elastin Mediated Vascular Stiffness on End Organs

NCT02840448
View directory record Official record
Conditions
Williams Syndrome, Supravalvular Aortic Stenosis, Cardiovascular Disease
Interventions
Not listed
Lead sponsor
National Heart, Lung, and Blood Institute (NHLBI)
NIH
Eligibility
3 Years to 85 Years
Enrollment
159 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2024
U.S. locations
2
States / cities
Bethesda, Maryland • St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Oct 8, 2026 · Synced Oct 22, 2026, 5:58 AM EDT