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Showing 25–43 of 19 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Contrast Allergies Clear all
Completed Phase 4 Interventional Accepts healthy volunteers

Visual Outcomes and Contrast Sensitivity After Myopic LASIK

NCT01746589
View directory record Official record
Conditions
Myopia
Interventions
bilateral myopic LASIK
Device
Lead sponsor
Daniel S. Durrie, MD
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Overland Park, Kansas
Source: ClinicalTrials.gov public record
Updated Jan 27, 2013 · Synced Sep 25, 2026, 9:10 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparison of Higher Order Aberrations and Contrast Sensitivity Between Acrysof SN60AT, SN60WF and Restore Intraocular Lenses

NCT00345085
View directory record Official record
Conditions
Refractive Errors
Interventions
Wavefront and Contrast Sensitivity
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 24, 2014 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Phase 2 Interventional

Single Oral Doses Study of Nerispirdine on Visual Function in Patients With Multiple Sclerosis

NCT00772525
View directory record Official record
Conditions
Multiple Sclerosis, Optic Nerve, Neuritis
Interventions
Nerispirdine, Placebo
Drug
Lead sponsor
Sanofi
Industry
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Bridgewater, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 25, 2016 · Synced Sep 25, 2026, 9:10 AM EDT
Completed No phase listed Observational

Reactions to Contrast Media (CM) Administered at the Time of the Endoscopic Retrograde Cholangiopancreatography (ERCP)

NCT00900640
View directory record Official record
Conditions
Contrast Allergies
Interventions
ERCP as medically indicated by subjects referring physician
Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 15, 2017 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

The Safety and Efficacy of Phentolamine Mesylate Ophthalmic Solution in Subjects With Severe Night Vision Disturbances

NCT01703559
View directory record Official record
Conditions
Night Vision Complaints, Decrease in Night Vision, Disturbance; Vision, Loss
Interventions
Phentolamine Mesylate Ophthalmic Solution 1.0%, Phentolamine Mesylate Ophthalmic Solution 0.5%, Phentolamine Mesylate Ophthalmic Solution Vehicle (Placebo)
Drug · Other
Lead sponsor
Ocuphire Pharma, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 31, 2019 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional

CT Scan Using IV Contrast Alone for Pediatric Appendicitis

NCT00716703
View directory record Official record
Conditions
Appendicitis, Child, Contrast Media
Interventions
CT Scan using IV contrast alone
Other
Lead sponsor
University of Rochester
Other
Eligibility
3 Years to 18 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2005
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jul 15, 2008 · Synced Sep 25, 2026, 9:10 AM EDT
Completed No phase listed Observational

The Relationship of Residence Time and Visual Effect of Optive and Systane in Dry Eye Subjects

NCT00553579
View directory record Official record
Conditions
Dry Eye Disease
Interventions
Not listed
Lead sponsor
Southern California College of Optometry at Marshall B. Ketchum University
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Fullerton, California
Source: ClinicalTrials.gov public record
Updated May 19, 2008 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Phase 1Phase 2 Interventional

The Safety and Efficacy Study of Ethylenediaminetetraacetic Acid (EDTA) Ophthalmic Solution in Patients With Loss of Contrast Sensitivity Due to Age-Related, Low-Grade Nuclear Cataract

NCT06365762
View directory record Official record
Conditions
Age Related Cataracts
Interventions
EDTA Ophthalmic Solution 2.6%, EDTA Ophthalmic Solution 1.3%, Saline Solution (Placebo)
Drug
Lead sponsor
Livionex Inc.
Industry
Eligibility
50 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
6
States / cities
San Francisco, California • Overland Park, Kansas • Lutherville, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2024 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Phase 4 Interventional Results available

Performance Assessment Tests in Working Individuals With DME Following Treatment With Ranibizumab

NCT02107131
View directory record Official record
Conditions
Diabetic Macular Edema
Interventions
Intravitreal ranibizumab 0.3mg
Drug
Lead sponsor
California Retina Consultants
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
6
States / cities
Bakersfield, California • Oxnard, California • Palmdale, California + 3 more
Source: ClinicalTrials.gov public record
Updated Dec 18, 2018 · Synced Sep 25, 2026, 9:10 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Building a Database of Results From People Without Eye Problems

NCT02627339
View directory record Official record
Conditions
Glaucoma
Interventions
Not listed
Lead sponsor
Wills Eye
Other
Eligibility
10 Years to 90 Years
Enrollment
208 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 20, 2016 · Synced Sep 25, 2026, 9:10 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Vision Measured by the Vimetrics CVA Compared With Chart Testing Under Similar Luminance and Contrast Conditions

NCT02028351
View directory record Official record
Conditions
Refractive Error, Cataract, Maculopathy
Interventions
Not listed
Lead sponsor
Sinclair Technologies, LLC
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 6, 2014 · Synced Sep 25, 2026, 9:10 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Neural and Visual Responses to Light in Bipolar Disorder: A Novel Putative Biomarker

NCT02048995
View directory record Official record
Conditions
Bipolar Depression
Interventions
Not listed
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 50 Years
Enrollment
91 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 28, 2018 · Synced Sep 25, 2026, 9:10 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Test-Retest Variability of Quick Contrast Sensitivity Function Testing

NCT02177669
View directory record Official record
Conditions
Healthy
Interventions
quick Contrast Sensitivity Function test
Other
Lead sponsor
Nova Southeastern University
Other
Eligibility
20 Years to 89 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Apr 10, 2017 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Evaluation of Electronic LogMar Visual Acuity and Contrast Sensitivity in a Population of Contact Lens Wearers

NCT03222037
View directory record Official record
Conditions
Visual Acuity
Interventions
senofilcon A, Control
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Sep 25, 2026, 9:10 AM EDT
Recruiting No phase listed Observational

Clinical Evaluation of Low Contrast Visual Performance and Low Light Phenomena in Patients With Various Intraocular Lens Implants

NCT07213167
View directory record Official record
Conditions
Dysphotopsia, Posterior Capsule Opacification, Visual Acuity, Visual Function, Contrast Sensitivity
Interventions
None-placebo
Other
Lead sponsor
Dr. Daniel H. Chang, MD
Other
Eligibility
22 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Bakersfield, California
Source: ClinicalTrials.gov public record
Updated Sep 24, 2026 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional

Diabetes Visual Function Supplement Study

NCT01646047
View directory record Official record
Conditions
Diabetes Mellitus - Type 1, Diabetes Mellitus - Type 2, Non-proliferative Diabetic Retinopathy
Interventions
multi-component nutritional supplement capsules, multi-component dietary supplement
Dietary Supplement
Lead sponsor
ZeaVision, LLC
Industry
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Tacoma, Washington
Source: ClinicalTrials.gov public record
Updated Jan 21, 2015 · Synced Sep 25, 2026, 9:10 AM EDT
Recruiting Not applicable Interventional

Contoura With Phorcides Compared to Wavefront Optimized LASIK

NCT05486546
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Contoura with Phorcides, WaveLight Wavefront Optimized
Procedure · Device
Lead sponsor
Daniel Terveen
Other
Eligibility
21 Years to 38 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
4
States / cities
Bozeman, Montana • Omaha, Nebraska • Fargo, North Dakota + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Sep 25, 2026, 9:10 AM EDT
Completed Not applicable Interventional Results available

The Zeaxanthin and Visual Function Study

NCT00564902
View directory record Official record
Conditions
Age Related Macular Degeneration, Cognition Disorders
Interventions
3R 3'R Zeaxanthin, Lutein, Lutein and Zeaxanthin
Drug · Dietary Supplement
Lead sponsor
Chrysantis, Inc.
Industry
Eligibility
45 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
North Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 28, 2012 · Synced Sep 25, 2026, 9:10 AM EDT
Withdrawn Phase 4 Interventional

Use of Gadolinium in CT Pulmonary Angiography

NCT02234375
View directory record Official record
Conditions
Pulmonary Embolism
Interventions
Gadolinium
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
20 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 16, 2020 · Synced Sep 25, 2026, 9:10 AM EDT