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Showing 1–24 of 43 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Contrast Sensitivity Clear all
Completed No phase listed Observational Accepts healthy volunteers

Building a Database of Results From People Without Eye Problems

NCT02627339
View directory record Official record
Conditions
Glaucoma
Interventions
Not listed
Lead sponsor
Wills Eye
Other
Eligibility
10 Years to 90 Years
Enrollment
208 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 20, 2016 · Synced Jun 10, 2026, 7:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Effect of a New Emulsion in Dry Eye Patients on Tear Layer Aberrometry, Contrast Sensitivity, and Reading Ability

NCT01013077
View directory record Official record
Conditions
Dry Eye Syndrome
Interventions
Optive, Soothe, New Emulsion, Soothe, New Emulsion, Optive, New Emulsion, Optive, Soothe
Other
Lead sponsor
Southern California College of Optometry at Marshall B. Ketchum University
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Fullerton, California
Source: ClinicalTrials.gov public record
Updated Jun 11, 2025 · Synced Jun 10, 2026, 7:30 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Evaluating NeuroVision's Neural Vision Correction (NVC) Myopia Treatment

NCT00469612
View directory record Official record
Conditions
Myopia
Interventions
NeuroVision's NVC treatment for Low Myopia
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 59 Years
Enrollment
2 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 24, 2018 · Synced Jun 10, 2026, 7:30 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Comparison of Higher Order Aberrations and Contrast Sensitivity Between Acrysof SN60AT, SN60WF and Restore Intraocular Lenses

NCT00345085
View directory record Official record
Conditions
Refractive Errors
Interventions
Wavefront and Contrast Sensitivity
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 24, 2014 · Synced Jun 10, 2026, 7:30 PM EDT
Recruiting Phase 3 Interventional

Privosegtor Investigation in Optic Neuropathies Efficacy Evaluation Research

NCT07623668
View directory record Official record
Conditions
Optic Neuritis
Interventions
Privosegtor, Methylprednisolone, Placebo
Drug · Other
Lead sponsor
Oculis
Industry
Eligibility
18 Years to 50 Years
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jun 10, 2026, 7:30 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Evaluation of Electronic LogMar Visual Acuity and Contrast Sensitivity in a Population of Contact Lens Wearers

NCT03222037
View directory record Official record
Conditions
Visual Acuity
Interventions
senofilcon A, Control
Device
Lead sponsor
Johnson & Johnson Vision Care, Inc.
Industry
Eligibility
18 Years to 35 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 9, 2019 · Synced Jun 10, 2026, 7:30 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Patient Centered Outcomes Analysis for MS Using a Mobile Application

NCT04281160
View directory record Official record
Conditions
Multiple Sclerosis
Interventions
BeCare Mobile App
Device
Lead sponsor
BeCare Link LLC
Industry
Eligibility
18 Years to 65 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 22, 2022 · Synced Jun 10, 2026, 7:30 PM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

The Safety and Efficacy of Phentolamine Mesylate Ophthalmic Solution in Subjects With Severe Night Vision Disturbances

NCT01703559
View directory record Official record
Conditions
Night Vision Complaints, Decrease in Night Vision, Disturbance; Vision, Loss
Interventions
Phentolamine Mesylate Ophthalmic Solution 1.0%, Phentolamine Mesylate Ophthalmic Solution 0.5%, Phentolamine Mesylate Ophthalmic Solution Vehicle (Placebo)
Drug · Other
Lead sponsor
Ocuphire Pharma, Inc.
Industry
Eligibility
18 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2012
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Jul 31, 2019 · Synced Jun 10, 2026, 7:30 PM EDT
Completed Phase 2Phase 3 Interventional Accepts healthy volunteers Results available

Topical ASP-1001 (Contrast Media Formulation) and the Acute Response to Nasal Allergen Challenge (NAC)

NCT00791102
View directory record Official record
Conditions
Allergic Rhinitis
Interventions
ASP-1001 nasal spray, Placebo for ASP-1001
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Days to 55 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 9, 2013 · Synced Jun 10, 2026, 7:30 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Baylor Infant and Toddler Biomarker of Nutrition Study

NCT05869760
View directory record Official record
Conditions
Healthy Nutrition, Healthy Diet
Interventions
Carotenoid Intake, Serum carotenoid concentrations
Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
3 Months to 24 Months
Enrollment
208 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Jun 10, 2026, 7:30 PM EDT
Completed Phase 2Phase 3 Interventional Results available

Ampyra for Optic Neuritis in Multiple Sclerosis

NCT01337986
View directory record Official record
Conditions
Multiple Sclerosis, Optic Neuritis
Interventions
Dalfampridine/Placebo, Placebo/Dalfampridine
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
18 Years to 55 Years
Enrollment
53 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jan 29, 2020 · Synced Jun 10, 2026, 7:30 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Vision Measured by the Vimetrics CVA Compared With Chart Testing Under Similar Luminance and Contrast Conditions

NCT02028351
View directory record Official record
Conditions
Refractive Error, Cataract, Maculopathy
Interventions
Not listed
Lead sponsor
Sinclair Technologies, LLC
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Elkins Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 6, 2014 · Synced Jun 10, 2026, 7:30 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Visual Discomfort and Reading

NCT00402155
View directory record Official record
Conditions
Visual Fatigue
Interventions
Stress on visual discomfort
Behavioral
Lead sponsor
Southern California College of Optometry at Marshall B. Ketchum University
Other
Eligibility
17 Years to 30 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Claremont, California
Source: ClinicalTrials.gov public record
Updated Nov 12, 2009 · Synced Jun 10, 2026, 7:30 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Combining Donepezil With Perceptual Learning in Normal and Amblyopic Human The Effect of Donepezil on Perceptual Learning in Adult Amblyopia

NCT03109314
View directory record Official record
Conditions
Amblyopia
Interventions
Donepezil, Single-letter training, Uncrowd training
Drug · Behavioral
Lead sponsor
Dennis Levi
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2018
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Jan 16, 2019 · Synced Jun 10, 2026, 7:30 PM EDT
Recruiting Not applicable Interventional

Contoura With Phorcides Compared to Wavefront Optimized LASIK

NCT05486546
View directory record Official record
Conditions
Myopia, Astigmatism
Interventions
Contoura with Phorcides, WaveLight Wavefront Optimized
Procedure · Device
Lead sponsor
Daniel Terveen
Other
Eligibility
21 Years to 38 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
4
States / cities
Bozeman, Montana • Omaha, Nebraska • Fargo, North Dakota + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 25, 2023 · Synced Jun 10, 2026, 7:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Visual Effect of an Investigational Artificial Tear in the Tear Layer.

NCT00395759
View directory record Official record
Conditions
Dry Eye Disease
Interventions
Optiva artificial tear by Allergan
Drug
Lead sponsor
Southern California College of Optometry at Marshall B. Ketchum University
Other
Eligibility
18 Years to 40 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2007
U.S. locations
1
States / cities
Fullerton, California
Source: ClinicalTrials.gov public record
Updated Oct 22, 2007 · Synced Jun 10, 2026, 7:30 PM EDT
Completed No phase listed Observational

The Relationship of Residence Time and Visual Effect of Optive and Systane in Dry Eye Subjects

NCT00553579
View directory record Official record
Conditions
Dry Eye Disease
Interventions
Not listed
Lead sponsor
Southern California College of Optometry at Marshall B. Ketchum University
Other
Eligibility
18 Years and older
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
1
States / cities
Fullerton, California
Source: ClinicalTrials.gov public record
Updated May 19, 2008 · Synced Jun 10, 2026, 7:30 PM EDT
Completed Phase 1Phase 2 Interventional

The Safety and Efficacy Study of Ethylenediaminetetraacetic Acid (EDTA) Ophthalmic Solution in Patients With Loss of Contrast Sensitivity Due to Age-Related, Low-Grade Nuclear Cataract

NCT06365762
View directory record Official record
Conditions
Age Related Cataracts
Interventions
EDTA Ophthalmic Solution 2.6%, EDTA Ophthalmic Solution 1.3%, Saline Solution (Placebo)
Drug
Lead sponsor
Livionex Inc.
Industry
Eligibility
50 Years and older
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
6
States / cities
San Francisco, California • Overland Park, Kansas • Lutherville, Maryland + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 15, 2024 · Synced Jun 10, 2026, 7:30 PM EDT
Completed Not applicable Interventional Results available

The Zeaxanthin and Visual Function Study

NCT00564902
View directory record Official record
Conditions
Age Related Macular Degeneration, Cognition Disorders
Interventions
3R 3'R Zeaxanthin, Lutein, Lutein and Zeaxanthin
Drug · Dietary Supplement
Lead sponsor
Chrysantis, Inc.
Industry
Eligibility
45 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
North Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Mar 28, 2012 · Synced Jun 10, 2026, 7:30 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Spaeth/Richman Contrast Sensitivity Test

NCT01300949
View directory record Official record
Conditions
Glaucoma
Interventions
Spaeth/Richman Contrast Sensitivity Test, Pelli-Robson Contrast Sensitivity Chart
Diagnostic Test
Lead sponsor
Wills Eye
Other
Eligibility
18 Years and older
Enrollment
314 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 10, 2018 · Synced Jun 10, 2026, 7:30 PM EDT
Completed Phase 2 Interventional Results available

Comparative Study of Sensitivity of Ga-DOTATOC PET vs Octreoscan SPECT + CT

NCT01869725
View directory record Official record
Conditions
Adult Medulloblastoma, Childhood Medulloblastoma, Neuroblastoma, Neuroendocrine Tumor, Somatostatinoma
Interventions
gallium Ga 68-edotreotide, positron emission tomography/computed tomography, indium In 111 pentetreotide, computed tomography, contrast-enhanced magnetic resonance imaging
Drug · Procedure · Radiation
Lead sponsor
Sue O'Dorisio
Other
Eligibility
2 Years and older
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 21, 2021 · Synced Jun 10, 2026, 7:30 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Test-Retest Variability of Quick Contrast Sensitivity Function Testing

NCT02177669
View directory record Official record
Conditions
Healthy
Interventions
quick Contrast Sensitivity Function test
Other
Lead sponsor
Nova Southeastern University
Other
Eligibility
20 Years to 89 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
Fort Lauderdale, Florida
Source: ClinicalTrials.gov public record
Updated Apr 10, 2017 · Synced Jun 10, 2026, 7:30 PM EDT
Withdrawn Phase 4 Interventional

A Feasibility Study to Assess the Use of Gadolinium in Computed Tomography

NCT02163005
View directory record Official record
Conditions
Contrast Media Allergy
Interventions
Gadolinium
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
56 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 3, 2021 · Synced Jun 10, 2026, 7:30 PM EDT
Completed No phase listed Observational

Assessment of Immediate Adverse Reactions From Dotarem in Children Under 2 Years of Age

NCT02609919
View directory record Official record
Conditions
Adverse Reaction to Drug, Allergic Reaction to Contrast Media
Interventions
Gadoteric Acid
Drug
Lead sponsor
St. Louis University
Other
Eligibility
Up to 2 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Sep 12, 2019 · Synced Jun 10, 2026, 7:30 PM EDT