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Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.

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Filters: Condition: Corneal Opacity Clear all

Conditions: Corneal Blindness
Interventions: KeraKlear Non-Penetrating Keratoprosthesis; Device
Lead sponsor: KeraMed, Inc.; Industry
Eligibility: 22 Years to 80 Years
Enrollment: 11 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 4
States / cities: Irvine, California • Edgewood, Kentucky • Boston, Massachusetts + 1 more

Conditions: Mucolipidosis Type IV
Interventions: Not listed
Lead sponsor: Baylor Research Institute; Other
Eligibility: 1 Year to 64 Years
Enrollment: 7 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2021
U.S. locations: 1
States / cities: Dallas, Texas

Conditions: CORNEAL OPACITY WITH POOR PROGNOSIS FOR CORNEAL TRANSPLANT
Interventions: Experimental; Other
Lead sponsor: University of California, Irvine; Other
Eligibility: 88 Years to 88 Years · Female only
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2019
U.S. locations: 1
States / cities: Irvine, California

Conditions: Intraocular Pressure, Corneal Opacity
Interventions: Loteprednol Etabonate 0.5% Oph Gel, Prednisolone Acetate 1% Oph Susp; Drug
Lead sponsor: University of Utah; Other
Eligibility: 21 Years and older
Enrollment: 131 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2014 – 2018
U.S. locations: 1
States / cities: Murray, Utah

Conditions: Keratoconus, Corneal Opacity, Corneal Dystrophy
Interventions: Optical Coherence Tomography; Device
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 14 Years to 85 Years
Enrollment: 445 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2018 – 2031
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Corneal Opacity, Keratoconus
Interventions: LALAK, IEK, Retrobulbar Block or General Anesthesia, optical coherence tomography (OCT), Topical Anesthesia, femtosecond laser; Procedure · Drug · Device
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years to 100 Years
Enrollment: 5 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2017
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Limbal Stem Cell Deficiency
Interventions: Biopsy to collect limbal epithelial stem cells that will be cultivated into a graft, Cultivation of Limbal epithelial cells into a graft, CALEC Transplant; Procedure · Biological
Lead sponsor: Massachusetts Eye and Ear Infirmary; Other
Eligibility: 18 Years to 89 Years
Enrollment: 23 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2016 – 2023
U.S. locations: 1
States / cities: Boston, Massachusetts

Conditions: Corneal Opacity
Interventions: Mitomycin-C, Fluorometholone 1% topical ocular steroid; Drug
Lead sponsor: United States Naval Medical Center, San Diego; Federal
Eligibility: 21 Years to 65 Years
Enrollment: 300 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2014 – 2023
U.S. locations: 1
States / cities: San Diego, California

Conditions: Corneal Opacities
Interventions: Not listed
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 1 Month to 18 Years
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2016
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Corneal Opacities (Scar and Stromal Dystrophy)
Interventions: Not listed
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years to 100 Years
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2025
U.S. locations: 1
States / cities: Portland, Oregon

Conditions: Corneal Opacity
Interventions: OCT guided laser-assisted lamellar anterior keratoplasty (LALAK), Penetrating Keratoplasty (KP); Procedure
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 1 Month to 18 Years
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2016
U.S. locations: 1
States / cities: Los Angeles, California

Conditions: Vision Disability
Interventions: Not listed
Lead sponsor: University Hospitals Cleveland Medical Center; Other
Eligibility: 18 Years and older
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2014
U.S. locations: 1
States / cities: Cleveland, Ohio

Conditions: Corneal Diseases
Interventions: Not listed
Lead sponsor: National Eye Institute (NEI); NIH
Eligibility: Not listed
Enrollment: 24 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2002 – 2005
U.S. locations: 1
States / cities: Bethesda, Maryland

Conditions: Corneal Disease, Corneal Opacity, Corneal Injuries
Interventions: CorNeat KPro; Device
Lead sponsor: CorNeat Vision Ltd.; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 10 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2023
U.S. locations: 1
States / cities: Edgewood, Kentucky

Conditions: Corneal Opacity
Interventions: OCT-guided laser phototherapeutic keratectomy; Drug
Lead sponsor: Oregon Health and Science University; Other
Eligibility: 18 Years and older
Enrollment: 80 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2011 – 2026
U.S. locations: 1
States / cities: Portland, Oregon