- Conditions
- Bicuspid Aortic Valve, Thoracic Aortic Aneurysm
- Interventions
- Cozaar
- Drug
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2014
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
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Showing 25–40
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- Conditions
- Bicuspid Aortic Valve
- Interventions
- Not listed
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 5,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2010 – 2040
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Heart Failure, Left Ventricle Remodeling
- Interventions
- Revivent TC System
- Device
- Lead sponsor
- BioVentrix
- Industry
- Eligibility
- 18 Years and older
- U.S. locations
- 2
- States / cities
- Cleveland, Ohio • Hershey, Pennsylvania
- Conditions
- Marfan Syndrome, Turner Syndrome, Ehlers-Danlos Syndrome, Loeys-Dietz Syndrome, FBN1, TGFBR1, TGFBR2, ACTA2 or MYH11 Genetic Mutation, Bicuspid Aortic Valve Without Known Family History, Bicuspid Aortic Valve With Family History, Bicuspid Aortic Valve With Coarctation, Familial Thoracic Aortic Aneurysm and Dissections, Shprintzen-Goldberg Syndrome, Other Aneur/Diss of Thoracic Aorta Not Due to Trauma, <50yo, Other Congenital Heart Disease
- Interventions
- Not listed
- Lead sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
- NIH
- Eligibility
- Not listed
- Enrollment
- 3,706 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2016
- U.S. locations
- 7
- States / cities
- Honolulu, Hawaii • Baltimore, Maryland • New York, New York + 3 more
- Conditions
- Other Acute Illnesses Presenting to the Hospital, Heart Failure, Pneumonia, Deep Venous Thrombosis, Cellulitis, Abdominal Aortic Aneurysm, Acute Cholecystitis, Peritoneal Free Fluid, Hydronephrosis, Pleural Effusion, Urinary Retention
- Interventions
- Not listed
- Lead sponsor
- VA Office of Research and Development
- Federal
- Eligibility
- Not listed
- Enrollment
- 116 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2020
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Coronary Artery Disease, Aortic Aneurysm, Pulmonary Embolism
- Interventions
- Not listed
- Lead sponsor
- Gilbert L. Raff, MD
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 2,640 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2011 – 2013
- U.S. locations
- 8
- States / cities
- San Diego, California • Boston, Massachusetts • Royal Oak, Michigan + 5 more
- Conditions
- Chest Pain, Acute Coronary Syndrome, Pulmonary Embolism, Aortic Dissection
- Interventions
- Not listed
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 30 Years and older
- Enrollment
- 102 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006 – 2009
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Aortic Aneurysm, Aortic Dissection, Bicuspid Aortic Valve (BAV), Heart Failure, Cardiovascular Diseases
- Interventions
- Not listed
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- Not listed
- Enrollment
- 15,000 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2053
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Ehlers-Danlos Syndrome, Stickler Syndrome, Marfan Syndrome
- Interventions
- Not listed
- Lead sponsor
- National Institute on Aging (NIA)
- NIH
- Eligibility
- 2 Years and older
- Enrollment
- 929 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2003 – 2015
- U.S. locations
- 1
- States / cities
- Baltimore, Maryland
- Conditions
- Congestive Heart Failure Exacerbation, Renal Insufficiency
- Interventions
- Natrecor, a recombinant form of B-type Natriuretic Peptide, made by Scios, Inc. vs. placebo
- Drug
- Lead sponsor
- Stanford University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2004 – 2006
- U.S. locations
- 1
- States / cities
- Stanford, California
- Conditions
- Vasodilatory Hypotension During or After Cardiac Surgery
- Interventions
- Angiotensin II
- Drug
- Lead sponsor
- University of Maryland St. Joseph Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Towson, Maryland
- Conditions
- Aortic Valve Stenosis, Aneurysm of Ascending Aorta, Aortic Valve Disorder, Bicuspid Valve Disorder
- Interventions
- Progel Vascular Sealant, Gelfoam Plus
- Device
- Lead sponsor
- C. R. Bard
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 158 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 19
- States / cities
- Los Angeles, California • Aurora, Colorado • Gainesville, Florida + 16 more
- Conditions
- Kawasaki Disease, Coronary Aneurysm
- Interventions
- Doxycycline, Placebo
- Drug
- Lead sponsor
- Hawaii Pacific Health
- Other
- Eligibility
- 1 Month to 21 Years
- Enrollment
- 26 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2026
- U.S. locations
- 1
- States / cities
- Honolulu, Hawaii
- Conditions
- Thoracic Aortic Aneurysm
- Interventions
- Spironolactone, Placebo
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 50 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2028
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Aortic Valve Insufficiency, Aortic Aneurysm
- Interventions
- Aortic valve repair
- Device
- Lead sponsor
- Biostable Science & Engineering
- Industry
- Eligibility
- Not listed
- Enrollment
- 183 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2024
- U.S. locations
- 5
- States / cities
- Indianapolis, Indiana • Ann Arbor, Michigan • St Louis, Missouri + 2 more
- Conditions
- PHACE Syndrome
- Interventions
- Not listed
- Lead sponsor
- Medical College of Wisconsin
- Other
- Eligibility
- Not listed
- Enrollment
- 341 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2022
- U.S. locations
- 1
- States / cities
- Milwaukee, Wisconsin