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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cortical Excitability Clear all
Recruiting Not applicable Interventional

Modulating Cortical Excitability to Improve Functional Movements in Individuals With Patellofemoral Pain

NCT06565520
View directory record Official record
Conditions
Patellofemoral Pain Syndrome
Interventions
transcranial direct current stimulator
Device
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
18 Years to 45 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Aug 21, 2024 · Synced Jun 25, 2026, 11:08 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Application of Transcranial Direct Current Stimulation (tDCS) in Patients With Chronic Pain After Spinal Cord Injury

NCT01112774
View directory record Official record
Conditions
Spinal Cord Injury
Interventions
Transcranial direct current stimulation
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 64 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 23, 2020 · Synced Jun 25, 2026, 11:08 PM EDT
Recruiting Not applicable Interventional

Endurance Exercise & Virtual Reality for Optimizing Cortical Excitability and Neuroplasticity in PD

NCT06133283
View directory record Official record
Conditions
Parkinson Disease
Interventions
High intensity endurance exercise, Stretching exercise, Virtual reality (VR)-based gaming
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
18 Years to 85 Years
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Jun 25, 2026, 11:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Encoding for Memory

NCT00051870
View directory record Official record
Conditions
Healthy
Interventions
Magstim Rapid Magnetic Stimulator
Device
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jun 25, 2026, 11:08 PM EDT
Completed Not applicable Interventional Results available

Finding an Optimal Latency for Paired Associative Stimulation in People With Chronic Stroke

NCT02188420
View directory record Official record
Conditions
Stroke
Interventions
Transcranial Magnetic Stimulation will be applied to the primary motor cortex at the interstimulus interval of ("Latency" - 3ms), Transcranial Magnetic Stimulation will be applied to the primary motor cortex at the interstimulus interval of ("Latency" - 5ms), ranscranial Magnetic Stimulation will be applied to the primary motor cortex at the interstimulus interval of ("Latency" - 7ms), Transcranial Magnetic Stimulation Time 100ms
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Feb 5, 2025 · Synced Jun 25, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Transcranial Magnetic Stimulation Used to Both Measure Cortical Excitability and Explore Methamphetamine Cue Craving

NCT01685463
View directory record Official record
Conditions
Methamphetamine Dependence
Interventions
Transcranial Magnetic Stimulation, Sham Transcranial Magnetic Stimulation
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 50 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2014
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 31, 2020 · Synced Jun 25, 2026, 11:08 PM EDT
Not listed Phase 3 Interventional

Cortical Excitability: Phenotype and Biomarker in Attention-deficit, Hyperactivity Disorder (ADHD) Therapy

NCT01330693
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity
Interventions
Atomoxetine, Sugar Pill
Drug
Lead sponsor
University of Cincinnati
Other
Eligibility
7 Years to 12 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
2
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 18, 2015 · Synced Jun 25, 2026, 11:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Effects of Antiepileptic Drugs on Brain Excitability

NCT00054990
View directory record Official record
Conditions
Healthy
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2004
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jun 25, 2026, 11:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

rTMS Induced Reduction in M1 Excitability

NCT07588113
View directory record Official record
Conditions
Cortical Excitability, Primary Motor Cortex, Motor Skills
Interventions
rTMS
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 45 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated May 31, 2026 · Synced Jun 25, 2026, 11:08 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Cortical Excitability in Cyclic Vomiting Syndrome

NCT05256160
View directory record Official record
Conditions
Cyclic Vomiting Syndrome
Interventions
TMS Paired-Pulse assessment of cortical excitability, Autonomic activity
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 60 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 23, 2025 · Synced Jun 25, 2026, 11:08 PM EDT
Not listed Phase 2 Interventional

Long- Term Transcranial Direct Current Stimulation in Parkinson's Disease

NCT03638531
View directory record Official record
Conditions
Parkinson Disease
Interventions
Anodal tDCS, SHAM tDCS
Device
Lead sponsor
University of Nevada, Las Vegas
Other
Eligibility
60 Years to 75 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Oct 18, 2018 · Synced Jun 25, 2026, 11:08 PM EDT
Completed Phase 1 Interventional

Preliminary Study of Transcranial Magnetic Stimulation for Stroke Rehabilitation

NCT00050128
View directory record Official record
Conditions
Cerebrovascular Accident
Interventions
rTMS, Magstim
Device
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2002 – 2007
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jun 25, 2026, 11:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Glutamate Probes in Adolescent Depression

NCT02307617
View directory record Official record
Conditions
Major Depressive Disorder, Major Depressive Disorder, Recurrent, Major Depressive Disorder, Remitted
Interventions
Not listed
Lead sponsor
Mayo Clinic
Other
Eligibility
13 Years to 21 Years
Enrollment
57 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 22, 2021 · Synced Jun 25, 2026, 11:08 PM EDT
Recruiting Not applicable Interventional

A Feasibility Trial of Virtual Reality Neurofeedback for Adolescents With Migraine

NCT07454798
View directory record Official record
Conditions
Migraine, Headache Disorders, Primary
Interventions
Immersive Neurofeedback Self-Regulation Training (INSeRT), Virtual Reality Imagery (No Neurofeedback)
Behavioral
Lead sponsor
Children's Mercy Hospital Kansas City
Other
Eligibility
10 Years to 16 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Kansas City, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jun 25, 2026, 11:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Inhibition of Muscle Movement in Normal Volunteers

NCT00047957
View directory record Official record
Conditions
Dystonic Disorders
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2005
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jun 25, 2026, 11:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Excitability in Patients With Succinic Semialdehyde Dehydrogenase Deficiency

NCT00132366
View directory record Official record
Conditions
Succinic Semialdehyde, Dehydrogenase Deficiency, Diseases
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
5 Years to 55 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2008
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jun 25, 2026, 11:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Cortical Excitability in Obsessive-Compulsive and Related Disorders

NCT00029068
View directory record Official record
Conditions
Obsessive Compulsive Disorder, Healthy
Interventions
Not listed
Lead sponsor
National Institute of Mental Health (NIMH)
NIH
Eligibility
Not listed
Enrollment
145 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2003
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 3, 2008 · Synced Jun 25, 2026, 11:08 PM EDT
Completed Phase 2 Interventional

Brain Stimulation to Treat Blepharospasm or Meige Syndrome

NCT00411255
View directory record Official record
Conditions
Blepharospasm, Focal Dystonia
Interventions
repetitive transcranial magnetic stimulation (rTMS)
Procedure
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2009
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jun 25, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Phase-dependent Evaluation of Motor Cortex Excitability With TMS in Stroke

NCT04968743
View directory record Official record
Conditions
Stroke
Interventions
Transcranial magnetic stimulation (TMS)
Device
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Nov 2, 2025 · Synced Jun 25, 2026, 11:08 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Menstrual Cycle TMS Plasticity Pilot

NCT07180654
View directory record Official record
Conditions
Cortical Activation
Interventions
transcranial magnetic stimulation
Device
Lead sponsor
University of Pennsylvania
Other
Eligibility
20 Years to 40 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 8, 2026 · Synced Jun 25, 2026, 11:08 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Brain Function in Focal Dystonia

NCT00102999
View directory record Official record
Conditions
Dystonia
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years and older
Enrollment
118 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2009
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 1, 2017 · Synced Jun 25, 2026, 11:08 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Glucose and Non-Invasive Brain Stimulation

NCT04031404
View directory record Official record
Conditions
Glucose Metabolism Disorders
Interventions
Single-pulse TMS
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 65 Years
Enrollment
23 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 26, 2021 · Synced Jun 25, 2026, 11:08 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Aging on Cortical Excitability and Motor Learning

NCT03750903
View directory record Official record
Conditions
Aging
Interventions
Aerobic Exercise, Stretching and Balance Training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 85 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Decatur, Washington
Source: ClinicalTrials.gov public record
Updated Apr 2, 2025 · Synced Jun 25, 2026, 11:08 PM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

iTBS Methods and Motor Cortex Excitability

NCT03584438
View directory record Official record
Conditions
Motor Activity
Interventions
Real iTBS, Sham iTBS
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 11, 2020 · Synced Jun 25, 2026, 11:08 PM EDT