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Showing 1–24 of 228 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Coughing Clear all
Recruiting No phase listed Observational Accepts healthy volunteers

Feasibility of Cough Monitoring in Children

NCT06587126
View directory record Official record
Conditions
Cystic Fibrosis in Children
Interventions
Curie Artificial Intelligence (AI) cough monitor
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
1 Year to 18 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Jun 27, 2026, 2:22 AM EDT
Completed Phase 2 Interventional Results available

A Study To Evaluate The Efficacy, Safety, Pharmacokinetics, And Pharmacodynamic Effects Of GDC-6599 In Patients With Chronic Cough

NCT05660850
View directory record Official record
Conditions
Chronic Refractory Cough (CRC) With Non-atopic Asthma, CRC With Atopic Asthma, Unexplained Chronic Cough, CRC With Chronic Obstructive Pulmonary Disease, CRC With Chronic Obstructive Pulmonary Disease With Chronic Bronchitis
Interventions
GDC-6599, GDC-6599-matching placebo, Mannitol
Drug · Other · Diagnostic Test
Lead sponsor
Genentech, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
49 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
8
States / cities
Los Angeles, California • Northridge, California • Coral Gables, Florida + 5 more
Source: ClinicalTrials.gov public record
Updated Dec 15, 2025 · Synced Jun 27, 2026, 2:22 AM EDT
Completed Phase 2 Interventional Results available

A Clinical Trial to Evaluate the Safety and Efficacy in Subjects With Chronic Cough

NCT05392192
View directory record Official record
Conditions
Chronic Cough
Interventions
ADX-629, Placebo
Drug
Lead sponsor
Aldeyra Therapeutics, Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
14
States / cities
San Diego, California • San Jose, California • Hollywood, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Feb 27, 2025 · Synced Jun 27, 2026, 2:22 AM EDT
Completed No phase listed Observational Results available

Assessment of Cough Reflex in Lung Transplant Recipients

NCT00584077
View directory record Official record
Conditions
Complication of Transplanted Lung
Interventions
Not listed
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2007
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Nov 1, 2018 · Synced Jun 27, 2026, 2:22 AM EDT
Completed Not applicable Interventional Results available

Sub-study to Spinal Cord Stimulation to Restore Cough

NCT00995215
View directory record Official record
Conditions
Spinal Cord Injuries, Spinal Cord Diseases, Paralysis, Central Nervous System Diseases, Cough
Interventions
Spinal Cord Stimulation, Expiratory Muscle Stimulator
Procedure · Device
Lead sponsor
MetroHealth Medical Center
Other
Eligibility
18 Years to 70 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2017
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 13, 2020 · Synced Jun 27, 2026, 2:22 AM EDT
Terminated Phase 3 Interventional Results available

Management of Recurrent Croup

NCT01748162
View directory record Official record
Conditions
Croup
Interventions
Fluticasone, Prednisolone IF needed
Drug
Lead sponsor
University of Michigan
Other
Eligibility
6 Months to 15 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 12, 2017 · Synced Jun 27, 2026, 2:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Increasing Vaccine Uptake Among Veterans at the Atlanta VA Health Care System

NCT03950986
View directory record Official record
Conditions
Influenza, Tetanus, Diphtheria, Pertussis, Pneumonia
Interventions
Modified clinical reminders
Other
Lead sponsor
Atlanta VA Medical Center
Federal
Eligibility
Not listed
Enrollment
67,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Decatur, Georgia
Source: ClinicalTrials.gov public record
Updated Jan 9, 2020 · Synced Jun 27, 2026, 2:22 AM EDT
Terminated No phase listed Observational

Chest Ultrasound of ER Patients With Cough or SOB

NCT02269761
View directory record Official record
Conditions
Cough, Dyspnea, Wheezing
Interventions
Nuvis Diagnostic Ultrasound System
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Mar 21, 2023 · Synced Jun 27, 2026, 2:22 AM EDT
Recruiting Early Phase 1 Interventional

Efficacy of Intramuscular Steroid Injection for Chronic Cough.

NCT06634823
View directory record Official record
Conditions
Chronic Cough (CC), Laryngeal Disease, Coughing
Interventions
Triamcinolone Acetonide Injectable Suspension, Saline injection
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jul 13, 2025 · Synced Jun 27, 2026, 2:22 AM EDT
Completed Not applicable Interventional

A Study to Test Lung Stretch Therapy (Hyperinsufflation) in Children With Collagen VI Muscular Dystrophy

NCT01836627
View directory record Official record
Conditions
Congenital Muscular Dystrophy
Interventions
Hyperinsufflation therapy
Other
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
5 Years to 20 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
2
States / cities
Cincinnati, Ohio • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 25, 2016 · Synced Jun 27, 2026, 2:22 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Rates of Pertussis Disease Among Persons Receiving Pentacel® or Other Pertussis Vaccines

NCT01129362
View directory record Official record
Conditions
Pertussis
Interventions
Pentacel® (DTaP-IPV/Hib), Other Pertussis Vaccines
Biological
Lead sponsor
Sanofi Pasteur, a Sanofi Company
Industry
Eligibility
Up to 59 Months
Enrollment
1,195 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
2
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Apr 24, 2022 · Synced Jun 27, 2026, 2:22 AM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Safety and Immunogenicity of Tdap Vaccine Compared to DTaP Vaccine in Children 4 to 6 Years of Age

NCT00467519
View directory record Official record
Conditions
Tetanus, Diphtheria, Pertussis
Interventions
Tdap (Tetanus Toxoid Reduced Diphtheria Toxoid/Acellular Pertussis), DTaP (Diphtheria & Tetanus Toxoids & Acellular Pertussis Adsorbed)
Biological
Lead sponsor
Sanofi Pasteur, a Sanofi Company
Industry
Eligibility
4 Years to 6 Years
Enrollment
1,045 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2009
U.S. locations
42
States / cities
Birmingham, Alabama • Fayetteville, Arkansas • Jonesboro, Arkansas + 34 more
Source: ClinicalTrials.gov public record
Updated Feb 6, 2014 · Synced Jun 27, 2026, 2:22 AM EDT
Completed Not applicable Interventional

Exploring a Cessation Intervention for Smokers

NCT01728038
View directory record Official record
Conditions
Asthma
Interventions
Cessation Counseling
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Not listed
Enrollment
230 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2016
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 29, 2017 · Synced Jun 27, 2026, 2:22 AM EDT
Withdrawn Phase 1 Interventional

Pulmozyme for Sjogren's Associated Cough

NCT01357447
View directory record Official record
Conditions
Sjogren's Syndrome, Cough
Interventions
Dornase alfa, Saline
Drug
Lead sponsor
UConn Health
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
1
States / cities
Farmington, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 17, 2020 · Synced Jun 27, 2026, 2:22 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Evaluating the Feasibility and Reliability of Using Handheld Nebulizers to Conduct Cough Sensitivity Testing With Citric Acid

NCT07531901
View directory record Official record
Conditions
Cough Reflex Sensitivity
Interventions
Cosmed QuarkSpiro Dosimeter-Controlled Nebulizer, DeVilbiss 45 Handheld Nebulizer
Device
Lead sponsor
University of Montana
Other
Eligibility
18 Years to 89 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Missoula, Montana
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jun 27, 2026, 2:22 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Surveillance Program to Determine Product Specific Rates of Invasive Hib Disease

NCT00855855
View directory record Official record
Conditions
Haemophilus Infections, Diphtheria, Tetanus, Polio, Pertussis
Interventions
DTaP-IPV/Hib
Biological
Lead sponsor
Sanofi Pasteur, a Sanofi Company
Industry
Eligibility
Up to 59 Months
Enrollment
20,830 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2014
U.S. locations
59
States / cities
Albany, California • Martinez, California • San Francisco, California + 56 more
Source: ClinicalTrials.gov public record
Updated Apr 24, 2022 · Synced Jun 27, 2026, 2:22 AM EDT
Completed No phase listed Observational

A Decentralized Study to Evaluate Physical Activity and Cough Frequency Using Wearable Technology in Cystic Fibrosis

NCT04923464
View directory record Official record
Conditions
Cystic Fibrosis
Interventions
Not listed
Lead sponsor
Vertex Pharmaceuticals Incorporated
Industry
Eligibility
18 Years and older
Enrollment
51 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
11
States / cities
Denver, Colorado • New Haven, Connecticut • Orlando, Florida + 8 more
Source: ClinicalTrials.gov public record
Updated Jan 18, 2022 · Synced Jun 27, 2026, 2:22 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Placebo-controlled, Single and Multiple Dose Study in Healthy Volunteers and Refractory Chronic Cough Patients to Assess the Safety, Tolerability, and Pharmacokinetics of Two Formulations of NTX-1175

NCT05628740
View directory record Official record
Conditions
Refractory Chronic Cough
Interventions
3 mg NOC-100 (via nebulizer), 1 mg NOC-110 (via DPI) [1x 1 mg capsule], 3 mg NOC-110 (via DPI), Placebo (via DPI), 6 mg NOC-110 (via DPI), Placebo (via DPI) [2x Placebo capsules]
Drug
Lead sponsor
Nocion Therapeutics
Industry
Eligibility
18 Years to 85 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
3
States / cities
Phoenix, Arizona • Leesburg, Florida • Winter Park, Florida
Source: ClinicalTrials.gov public record
Updated Mar 29, 2023 · Synced Jun 27, 2026, 2:22 AM EDT
Completed Phase 2 Interventional Results available

Study of the Efficacy, Safety, and Tolerability of Serlopitant for the Treatment of Refractory Chronic Cough

NCT03282591
View directory record Official record
Conditions
Refractory Chronic Cough
Interventions
5 mg Serlopitant Tablets, Matching Placebo Tablets
Drug
Lead sponsor
Vyne Therapeutics Inc.
Industry
Eligibility
18 Years to 80 Years
Enrollment
185 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
29
States / cities
Los Angeles, California • Mission Viejo, California • San Diego, California + 24 more
Source: ClinicalTrials.gov public record
Updated May 19, 2021 · Synced Jun 27, 2026, 2:22 AM EDT
Completed No phase listed Observational

Dysphagia in Thoracic Surgical Patients

NCT04487028
View directory record Official record
Conditions
Thoracic Diseases
Interventions
Fiberoptic Endoscopic Evaluation of Swallowing
Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Enrollment
61 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
3
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Nov 23, 2021 · Synced Jun 27, 2026, 2:22 AM EDT
Terminated Not applicable Interventional Results available

Retrospective TIF Study for Treatment of Gastroesophageal Reflux Disease (GERD). The RetroTIF Study

NCT01327963
View directory record Official record
Conditions
Gastroesophageal Reflux Disease (GERD)
Interventions
Transoral Incisionless Fundoplication
Device
Lead sponsor
EndoGastric Solutions
Industry
Eligibility
18 Years to 85 Years
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Ocala, Florida • Salem, Kentucky
Source: ClinicalTrials.gov public record
Updated Dec 2, 2020 · Synced Jun 27, 2026, 2:22 AM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

The Safety of Boostrix Following Routine Immunization of Pregnant Women

NCT03463577
View directory record Official record
Conditions
Whooping Cough
Interventions
Safety assessment following routine immunization with Boostrix
Other
Lead sponsor
GlaxoSmithKline
Industry
Eligibility
Female only
Enrollment
65,783 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Pasadena, California
Source: ClinicalTrials.gov public record
Updated May 17, 2022 · Synced Jun 27, 2026, 2:22 AM EDT
Active, not recruiting Not applicable Interventional

Cough, Expiratory Training, and Chronic Aspiration After Head and Neck Radiotherapy

NCT02662907
View directory record Official record
Conditions
Head and Neck Cancer
Interventions
Barium Swallow, Questionnaires, Expiratory Muscle Strength Training (EMST) Device, Digital Manometer, Neurocognitive Exams, Barium
Procedure · Behavioral · Device + 1 more
Lead sponsor
M.D. Anderson Cancer Center
Other
Eligibility
18 Years and older
Enrollment
175 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 15, 2026 · Synced Jun 27, 2026, 2:22 AM EDT
Terminated Not applicable Interventional Results available

HFNC Effect on BCSS in Patients With COPD

NCT02825043
View directory record Official record
Conditions
Chronic Obstructive Pulmonary Disease
Interventions
High-Flow Nasal Cannula
Device
Lead sponsor
University of Oklahoma
Other
Eligibility
35 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 28, 2020 · Synced Jun 27, 2026, 2:22 AM EDT