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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Craniocerebral Trauma Clear all
Completed No phase listed Observational Accepts healthy volunteers

Eye-Tracking Rapid Attention Computation

NCT00743821
View directory record Official record
Conditions
Post Concussive Syndrome, Chronic
Interventions
Not listed
Lead sponsor
Brain Trauma Foundation
Other
Eligibility
18 Years to 55 Years
Enrollment
426 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated May 6, 2014 · Synced Sep 29, 2026, 4:50 PM EDT
Not yet recruiting Not applicable Interventional

Cervico-vestibular Home Exercise Program Feasibility

NCT07099248
View directory record Official record
Conditions
Concussion, Sports Injuries in Children
Interventions
Cervico-vestibular Home Exercise Program
Other
Lead sponsor
Texas Scottish Rite Hospital for Children
Other
Eligibility
Up to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Frisco, Texas
Source: ClinicalTrials.gov public record
Updated Jul 31, 2025 · Synced Sep 29, 2026, 4:50 PM EDT
Completed Not applicable Interventional Results available

Amantadine + rTMS as a Neurotherapeutic for Disordered Consciousness

NCT02025439
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
rTMS, Amantadine
Device · Drug
Lead sponsor
Edward Hines Jr. VA Hospital
Federal
Eligibility
18 Years to 64 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
2
States / cities
Chicago, Illinois • Hines, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 23, 2020 · Synced Sep 29, 2026, 4:50 PM EDT
Completed No phase listed Observational

Evaluating a Novel Method of EEG Evoked Response Potential Analysis in Concussion Assessment

NCT03265912
View directory record Official record
Conditions
Concussion, Mild, TBI (Traumatic Brain Injury), Mild Traumatic Brain Injury
Interventions
Not listed
Lead sponsor
ElMindA Ltd
Industry
Eligibility
15 Years to 50 Years
Enrollment
46 participants
Timeline
2017 – 2018
U.S. locations
2
States / cities
New York, New York • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 26, 2018 · Synced Sep 29, 2026, 4:50 PM EDT
Recruiting Not applicable Interventional

Percutaneous Electrical Nerve Field Stimulation (PENFS) in Patients With Post Concussion Syndrome (PCS)

NCT04978571
View directory record Official record
Conditions
Post-Concussion Syndrome, COVID Long-Haul, COVID-19
Interventions
percutaneous electrical nerve-field stimulation, PENFS, percutaneous electrical nerve-field stimulation, PENFS (sham device), percutaneous electrical nerve-field stimulation, PENFS (COVID active device)
Device
Lead sponsor
Children's Hospital of Orange County
Other
Eligibility
11 Years to 18 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
1
States / cities
Orange, California
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Sep 29, 2026, 4:50 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Assessment of Traumatic Brain Injury Using Transcranial Magnetic Stimulated Evoked Potentials

NCT06963775
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Delphi-MD device (QuantalX Neuroscience Ltd., Saba Israel)
Device
Lead sponsor
Ramon Diaz-Arrastia
Other
Eligibility
18 Years and older
Enrollment
215 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2030
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2026 · Synced Sep 29, 2026, 4:50 PM EDT
Completed Not applicable Interventional

Speed of Processing Training to Improve Cognition in Traumatic Brain Injury and Mild Cognitive Impairment

NCT02020564
View directory record Official record
Conditions
Traumatic Brain Injury, Mild Cognitive Impairment
Interventions
Speed of Processing Training, Placebo Control
Behavioral
Lead sponsor
Kessler Foundation
Other
Eligibility
18 Years to 59 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2022
U.S. locations
1
States / cities
East Hanover, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 17, 2023 · Synced Sep 29, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Mayo Clinic Traumatic Brain Injury Model System Center: The CONNECT Trial

NCT02088099
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Complex clinical intervention, Treatment as usual
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
426 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Sep 30, 2019 · Synced Sep 29, 2026, 4:50 PM EDT
Recruiting Not applicable Interventional

Concussion Health Improvement Program

NCT06036147
View directory record Official record
Conditions
Concussion, Brain, Brain Injury Traumatic Mild
Interventions
Concussion-focused cognitive behavioral therapy, Parent skills training, Care management
Behavioral
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
11 Years to 18 Years
Enrollment
304 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2028
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Mar 12, 2025 · Synced Sep 29, 2026, 4:50 PM EDT
Recruiting No phase listed Observational

Cerebral Autoregulation, Brain Perfusion, and Neurocognitive Outcomes After Traumatic Brain Injury

NCT06480838
View directory record Official record
Conditions
Traumatic Brain Injury With Loss of Consciousness, Brain Injury Traumatic Severe, Brain Injury Traumatic Moderate, TBI (Traumatic Brain Injury), TBI
Interventions
Not listed
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 80 Years
Enrollment
130 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2029
U.S. locations
3
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Jul 1, 2026 · Synced Sep 29, 2026, 4:50 PM EDT
Terminated No phase listed Observational Accepts healthy volunteers

Characterization of Human Autoantibody Titers After Central Nervous System Insult

NCT03089749
View directory record Official record
Conditions
Brain Injuries, Traumatic, Spinal Cord Trauma, Intracranial Neoplasm
Interventions
Not listed
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
63 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Sep 29, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Bright Light Therapy for Treatment of Sleep Problems Following Mild Traumatic Brain Injury

NCT02374918
View directory record Official record
Conditions
Concussion, Mild, Post-Concussion Symptoms, Sleep Problems
Interventions
mTBI wavelength-1 bright light, mTBI wavelength-2 bright light, HC wavelength-1 bright light, HC wavelength-2 bright light
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 50 Years
Enrollment
77 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
Tucson, Arizona
Source: ClinicalTrials.gov public record
Updated Jun 23, 2021 · Synced Sep 29, 2026, 4:50 PM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Detection of Vocal Fold Motion Impairment on Noninvasive Positive Pressure

NCT06406725
View directory record Official record
Conditions
Vocal Cord Dysfunction, Vocal Cord Paralysis, Vocal Cord Paresis, Recurrent Laryngeal Nerve Palsy, Recurrent Laryngeal Nerve Injuries
Interventions
Point-of-Care Ultrasound of the Airway
Diagnostic Test
Lead sponsor
Nemours Children's Clinic
Other
Eligibility
1 Day to 18 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Queens, New York
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 29, 2026, 4:50 PM EDT
Completed Not applicable Interventional

High Intensity Exercise and Improving Physical Activity Among People With Neurologic Dysfunction

NCT06945835
View directory record Official record
Conditions
Cerebral Palsy (CP), Stroke, Spinal Cord Injury, Traumatic Brain Injury, Charcot Marie Tooth Disease (CMT), Spina Bifida
Interventions
Participate in high intensity exercise of at least 20 minutes in 60 minutes session of RPE greater than 6.
Behavioral
Lead sponsor
University of Hartford
Other
Eligibility
8 Years to 99 Years
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
West Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Nov 2, 2025 · Synced Sep 29, 2026, 4:50 PM EDT
Recruiting Not applicable Interventional

Transcutaneous Auricular Neurostimulation for ICU Patients With Traumatic Brain Injury

NCT06467708
View directory record Official record
Conditions
TBI (Traumatic Brain Injury)
Interventions
Sparrow Ascent Transcutaneous Auricular Neurostimulation (tAN)
Device
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Feb 17, 2026 · Synced Sep 29, 2026, 4:50 PM EDT
Completed Not applicable Interventional

Longitudinal, Multi-Dimensional Assessment of Recovery and Added Benefit of a Behavioral Health Intervention for Children With Abusive Head Trauma

NCT03447899
View directory record Official record
Conditions
Non-Accidental Traumatic Head Injury to Child
Interventions
Attachment and Biobehavioral Catch-up (ABC)
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
3 Months to 2 Years
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 9, 2020 · Synced Sep 29, 2026, 4:50 PM EDT
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Brain and Gut Plasticity in Mild TBI or Post-acute COVID Syndrome Following Growth Hormone Therapy

NCT03554265
View directory record Official record
Conditions
Traumatic Brain Injury, Fatigue, Cognitive Impairment, COVID-19
Interventions
Somatropin
Drug
Lead sponsor
The University of Texas Medical Branch, Galveston
Other
Eligibility
18 Years to 70 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2023
U.S. locations
1
States / cities
Galveston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 4, 2025 · Synced Sep 29, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

How do the Neck Muscles Influence Head Acceleration During Sport-associated Impact Events in High School Athletes?

NCT03883165
View directory record Official record
Conditions
Sport-related Concussion, Brain Concussion, Healthy
Interventions
high-intensity neck strengthening, Control group
Other
Lead sponsor
University of Michigan
Other
Eligibility
13 Years to 19 Years
Enrollment
48 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 23, 2025 · Synced Sep 29, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Traumatic Brain Injury and Alzheimer's Disease/Related Dementias Caregiver Support Intervention

NCT05465109
View directory record Official record
Conditions
Caregiver Burden, Caregiver Stress Syndrome, Caregiver Burnout
Interventions
TBI-AD/ADRD Caregiver Support Intervention (TACSI)
Other
Lead sponsor
University of Minnesota
Other
Eligibility
21 Years and older
Enrollment
95 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 21, 2025 · Synced Sep 29, 2026, 4:50 PM EDT
Completed No phase listed Observational

EyeBOX Concussion Study and Registry

NCT03966404
View directory record Official record
Conditions
Concussion, Brain, Mild Traumatic Brain Injury
Interventions
EyeBOX device
Diagnostic Test
Lead sponsor
Oculogica, Inc.
Industry
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
1
States / cities
White Plains, New York
Source: ClinicalTrials.gov public record
Updated Sep 6, 2023 · Synced Sep 29, 2026, 4:50 PM EDT
Terminated Not applicable Interventional

Post-concussion Syndrome and Chiropractic

NCT06151184
View directory record Official record
Conditions
Post-Concussion Syndrome
Interventions
Chiropractic adjustment
Procedure
Lead sponsor
Life University
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 24, 2026 · Synced Sep 29, 2026, 4:50 PM EDT
Completed Not applicable Interventional

Acupressure and Stress Resilience

NCT01614444
View directory record Official record
Conditions
Post-traumatic Stress Disorder (PTSD), Mild Traumatic Brain Injury (mTBI)
Interventions
Active Acupressure Treatment, Placebo Acupressure Treatment
Other
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated May 18, 2017 · Synced Sep 29, 2026, 4:50 PM EDT
Completed Phase 3 Interventional

Traumatic Brain Injury - Knowledge Translation

NCT01453621
View directory record Official record
Conditions
Traumatic Brain Injury
Interventions
Computerized clinical decision support
Other
Lead sponsor
Columbia University
Other
Eligibility
Not listed
Enrollment
28,669 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 15, 2015 · Synced Sep 29, 2026, 4:50 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Brain Oximeter Calibration and Validation Study

NCT05397704
View directory record Official record
Conditions
Brain Injuries, Traumatic
Interventions
brain pulse oximeter
Device
Lead sponsor
Cyban Pty Ltd
Industry
Eligibility
18 Years to 45 Years
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 1, 2023 · Synced Sep 29, 2026, 4:50 PM EDT