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ClinicalTrials.gov public records Last synced Oct 2, 2026, 5:41 AM EDT

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Showing 25–48 of 169 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Critical Care, Intensive Care Clear all
Completed Phase 4 Interventional

Preventing ICU Subsyndromal Delirium Conversion to Delirium With Haloperidol

NCT01174290
View directory record Official record
Conditions
Subsyndromal Delirium
Interventions
Haloperidol decanoate, Placebo
Drug
Lead sponsor
Northeastern University
Other
Eligibility
18 Years to 84 Years
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 14, 2017 · Synced Oct 2, 2026, 5:41 AM EDT
Active, not recruiting No phase listed Observational

Measuring Outcomes of Activity in Intensive Care

NCT03115840
View directory record Official record
Conditions
Critical Illness, Sepsis, Mechanical Ventilation, Physical Activity, Disability Physical, Muscle Weakness, Cognitive Impairment
Interventions
Not listed
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2030
U.S. locations
2
States / cities
Columbus, Ohio • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 3, 2026 · Synced Oct 2, 2026, 5:41 AM EDT
Completed No phase listed Observational

Post-Intensive Care Syndrome - Pediatrics (PICS-p): Longitudinal Cohort Study

NCT04967365
View directory record Official record
Conditions
Critical Illness, Post Intensive Care Unit Syndrome
Interventions
Not listed
Lead sponsor
University of Pennsylvania
Other
Eligibility
1 Month to 16 Years
Enrollment
755 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
30
States / cities
Birmingham, Alabama • Little Rock, Arkansas • Los Angeles, California + 26 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2026 · Synced Oct 2, 2026, 5:41 AM EDT
Recruiting Not applicable Interventional

The Effects of Endotracheal Suctioning on Pain and Serum Markers

NCT06692400
View directory record Official record
Conditions
Intensive Care Unit ICU, Intubation, Critical Illness, Mechanical Ventilation, Pain Measurement, Pain, Procedural, Oxidative Stress, Hypoxia, Biomarkers / Blood, Adult, Uric Acid, Sepsis, COVID, Influenza, Pneumonia
Interventions
endotracheal tube suctioning
Procedure
Lead sponsor
Loma Linda University
Other
Eligibility
18 Years and older
Enrollment
110 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 2, 2026, 5:41 AM EDT
Completed Not applicable Interventional Results available

Isotonic Solutions and Major Adverse Renal Events Trial in the Non-Medical Intensive Care Unit (SMART-SURG)

NCT02547779
View directory record Official record
Conditions
Critical Illness, Acute Kidney Injury
Interventions
0.9% Saline, Physiologically-balanced isotonic crystalloid
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
10,421 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Nov 25, 2019 · Synced Oct 2, 2026, 5:41 AM EDT
Completed No phase listed Observational

Clinical Study of the Intravenous Blood Glucose System in Hospitalized Adult Elective or Non-Emergent Surgery and Medical/Surgical Intensive Care Unit Patients

NCT00906490
View directory record Official record
Conditions
Blood Glucose
Interventions
Intravenous Blood Glucose monitoring system
Device
Lead sponsor
Edwards Lifesciences
Industry
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
5
States / cities
Washington D.C., District of Columbia • Baltimore, Maryland • Minneapolis, Minnesota + 2 more
Source: ClinicalTrials.gov public record
Updated Aug 20, 2013 · Synced Oct 2, 2026, 5:41 AM EDT
Completed Phase 4 Interventional Results available

Pharmacokinetics of Daptomycin in Critically Ill Patients Receiving Continuous Venovenous Hemodialysis (CVVHD)

NCT00663403
View directory record Official record
Conditions
Critically Ill, Hemodialysis
Interventions
Daptomycin
Drug
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 30, 2015 · Synced Oct 2, 2026, 5:41 AM EDT
Not listed Not applicable Interventional

Peer Support for Post Intensive Care Syndrome Self-Management

NCT03788096
View directory record Official record
Conditions
Critical Illness, Sepsis, Shock, Septic, Shock, Respiratory Failure, Respiratory Distress Syndrome, Adult, Shock, Hypovolemic, Chronic Disease
Interventions
Peer Support with Motivational Interviewing, Usual Care Group
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 65 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Temple, Texas
Source: ClinicalTrials.gov public record
Updated Nov 2, 2020 · Synced Oct 2, 2026, 5:41 AM EDT
Completed Not applicable Interventional Results available

Acupuncture to Improve Comfort of Children on a Ventilator in the Intensive Care Unit

NCT01848158
View directory record Official record
Conditions
Agitation
Interventions
acupuncture, sham acupuncture
Device
Lead sponsor
Seattle Children's Hospital
Other
Eligibility
6 Months to 17 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2016
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Aug 13, 2020 · Synced Oct 2, 2026, 5:41 AM EDT
Completed Phase 2 Interventional

CYCLE Pilot Randomized Trial

NCT02377830
View directory record Official record
Conditions
Intensive Care Unit Acquired Weakness, Critical Care, Mechanical Ventilation, Respiratory Failure
Interventions
In-bed cycle ergometer (Restorative Therapies RT300 Supine), Routine physiotherapy
Device · Other
Lead sponsor
McMaster University
Other
Eligibility
18 Years and older
Enrollment
113 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 5, 2022 · Synced Oct 2, 2026, 5:41 AM EDT
Completed No phase listed Observational

Multicenter Intensivist Weekend Scheduling Study

NCT01145443
View directory record Official record
Conditions
Critical Illness, Burnout, Professional
Interventions
Alternative Intensivist staffing models.
Other
Lead sponsor
University of Manitoba
Other
Eligibility
17 Years and older
Enrollment
1,945 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
4
States / cities
Indianapolis, Indiana • Cleveland, Ohio • Columbus, Ohio + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 16, 2010 · Synced Oct 2, 2026, 5:41 AM EDT
Completed Not applicable Interventional

Family Support Intervention in Intensive Care Units (The Four Supports Study)

NCT01107704
View directory record Official record
Conditions
Physician-Family Communication in Intensive Care Units, Surrogate Decision-making for Critically Ill Patients
Interventions
Family Support Intervention
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
50 Years and older
Enrollment
159 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 27, 2014 · Synced Oct 2, 2026, 5:41 AM EDT
Recruiting Not applicable Interventional

Pharmacist-Intensivist Collaborative Telehealth for Post-Intensive Care Syndrome

NCT06983496
View directory record Official record
Conditions
Post Intensive Care Syndrome (PICS)
Interventions
Post-ICU Telehealth Follow-up
Behavioral
Lead sponsor
Malcom Randall VA Medical Center
Federal
Eligibility
18 Years to 89 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Sep 23, 2025 · Synced Oct 2, 2026, 5:41 AM EDT
Recruiting Not applicable Interventional

Effect of Giving Reduced Fluid in Children After Trauma

NCT04201704
View directory record Official record
Conditions
Critical Illness, Pediatrics, General Surgery, Fluid Therapy, Wounds and Injuries
Interventions
Balanced crystalloid solution volume administration, Packed Erythrocytes Units, Blood Product Unit volume, Plasma volume, Platelets volume
Other
Lead sponsor
Columbia University
Other
Eligibility
6 Months to 15 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2027
U.S. locations
4
States / cities
Buffalo, New York • New York, New York • Rochester, New York + 1 more
Source: ClinicalTrials.gov public record
Updated May 7, 2026 · Synced Oct 2, 2026, 5:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effect of Intensivist Communication on Surrogate Prognosis Interpretation

NCT04239209
View directory record Official record
Conditions
Critical Illness
Interventions
Indirect - other patients, Indirect - physiology, Redirection, Direct communication
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
302 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jan 27, 2020 · Synced Oct 2, 2026, 5:41 AM EDT
Completed Not applicable Interventional

Optimizing Outcomes With Physical Therapy Treatment for IndividuALs Surviving an ICU Admission for Covid-19

NCT04412330
View directory record Official record
Conditions
Covid-19, Critical Illness, Post Intensive Care Unit Syndrome, Muscle Weakness
Interventions
ICU Recovery + Physical Therapy
Other
Lead sponsor
University of Kentucky
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Jun 11, 2021 · Synced Oct 2, 2026, 5:41 AM EDT
Not listed Not applicable Interventional

RCT: Early Feeding After PEG Placement

NCT04110613
View directory record Official record
Conditions
Critical Illness, Malnutrition, Gastrostomy, Procedural Sequelae, Trauma, Surgery, Mechanical Ventilation
Interventions
noFast: Start tube feeds within 1 hour of procedure
Dietary Supplement
Lead sponsor
Carilion Clinic
Other
Eligibility
18 Years to 100 Years
Enrollment
1,200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Roanoke, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 26, 2021 · Synced Oct 2, 2026, 5:41 AM EDT
Completed Not applicable Interventional Results available

Mobile Critical Care Recovery Program for Acute Respiratory Failure Survivors

NCT03053245
View directory record Official record
Conditions
Acute Respiratory Failure, Post-Intensive Care Syndrome
Interventions
Mobile Critical Care Program, Attention Control
Behavioral
Lead sponsor
Indiana University
Other
Eligibility
18 Years and older
Enrollment
503 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
3
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Jun 24, 2024 · Synced Oct 2, 2026, 5:41 AM EDT
Not listed No phase listed Observational

Critical Illness Outcomes Study

NCT01109719
View directory record Official record
Conditions
Critical Illness, Intensive Care, Intensive Care Unit
Interventions
Not listed
Lead sponsor
National Institute of General Medical Sciences (NIGMS)
NIH
Eligibility
18 Years and older
Enrollment
6,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Aug 25, 2010 · Synced Oct 2, 2026, 5:41 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Testing of a New Therapeutic Vibration Device to Reduce Neuromuscular Weakness in Hospitalized Patients

NCT03479008
View directory record Official record
Conditions
Critically Ill, Post Intensive Care Syndrome
Interventions
Therapeutic Vibration Device
Diagnostic Test
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 30, 2024 · Synced Oct 2, 2026, 5:41 AM EDT
Terminated Not applicable Interventional

Brain Computer Interface for Communication in Ventilated Patients

NCT02791425
View directory record Official record
Conditions
Mechanical Ventilation, Nonverbal Communication, Intratracheal Intubation, Critical Illness
Interventions
Brain Computer Interface (BCI) device, Communication picture board
Device · Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced Oct 2, 2026, 5:41 AM EDT
Not listed Phase 2 Interventional

Improving Blood Glucose Control With a Computerized Decision Support Tool: Phase 2

NCT00654797
View directory record Official record
Conditions
Critically Ill, Hyperglycemia
Interventions
glucose control with computer generated recommendations
Procedure
Lead sponsor
Intermountain Health Care, Inc.
Other
Eligibility
1 Month and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2018
U.S. locations
10
States / cities
Madera, California • Saint Paul, Minnesota • Lebanon, New Hampshire + 5 more
Source: ClinicalTrials.gov public record
Updated Feb 26, 2015 · Synced Oct 2, 2026, 5:41 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

Point-of-Care AI Assistance and Critical Care Outcomes: A Randomized Trial

NCT07293078
View directory record Official record
Conditions
Critical Illness, Sepsis, Acute Respiratory Failure (ARF), Multi-organ Failure, Acute Kidney Injury, Delirium Confusional State, Shock
Interventions
Point-of-care large language model decision support (ChatGPT-5)
Other
Lead sponsor
MetroWest Artificial Intelligence Research Workgroup
Other
Eligibility
18 Years and older
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
Framingham, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Oct 2, 2026, 5:41 AM EDT
Completed No phase listed Observational

NGAL As An Aid for the Diagnosis of Acute Kidney Injury in Intensive Care

NCT02121470
View directory record Official record
Conditions
Acute Kidney Injury
Interventions
Not listed
Lead sponsor
BioPorto Diagnostics
Industry
Eligibility
18 Years and older
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
4
States / cities
Boston, Massachusetts • Springfield, Massachusetts • The Bronx, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 11, 2015 · Synced Oct 2, 2026, 5:41 AM EDT