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Showing 1–24 of 44 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Crush Injury Clear all
Suspended Not applicable Interventional

The PROTECT 2 Study : Pressure Injury Treatment by Intermittent Electrical Stimulation: A Randomized, Controlled Trial

NCT05085288
View directory record Official record
Conditions
Stage 1 Pressure Ulcer, Stage 2 Pressure Ulcer
Interventions
Intermittent electrical stimulation system (IES) treatment and turning patient every two hours, Turning population every two hours
Device · Other
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
1,100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
2
States / cities
Winston-Salem, North Carolina • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 17, 2026 · Synced Sep 8, 2026, 2:48 PM EDT
Completed Not applicable Interventional

A Prospective, Multi Centre, Interventional, Non-comparator, Open Label Study to Demonstrate the Efficacy, Safety, and Performance of ConvaFoam™ Dressings in the Management of Indicated Chronic Wound Types.

NCT05632250
View directory record Official record
Conditions
Chronic Ulcer of Leg or Foot, Pressure Injury
Interventions
ConvaFoam
Device
Lead sponsor
ConvaTec Inc.
Industry
Eligibility
18 Years and older
Enrollment
95 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2024
U.S. locations
5
States / cities
Hagerstown, Maryland • Mineola, New York • Raleigh, North Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2024 · Synced Sep 8, 2026, 2:48 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

A Comparison of Two Injection Locations in Obese Patients Having Lower Leg/Foot Surgery

NCT01550094
View directory record Official record
Conditions
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/ or Foot, Complete Tear, Ankle and/or Foot Ligament, Pathological Fracture - Ankle and/or Foot, Loose Body in Joint of Ankle and/or Foot
Interventions
Not listed
Lead sponsor
Jose Soberon, MD
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2015
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Oct 13, 2015 · Synced Sep 8, 2026, 2:48 PM EDT
Completed Not applicable Interventional

Effect of Total Compression Time and Rate (Slope) on Incidence of Symptomatic ETD and MEB: A Phase II Prospective Study.

NCT04776967
View directory record Official record
Conditions
Eustachian Tube Dysfunction, Middle Ear Barotrauma, Middle Ear Disease, Middle Ear; Injury, Pressure Injury, Ear Barotrauma
Interventions
Hyperbaric Compression Profile
Procedure
Lead sponsor
Northwell Health
Other
Eligibility
Not listed
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Sleepy Hollow, New York
Source: ClinicalTrials.gov public record
Updated Aug 18, 2021 · Synced Sep 8, 2026, 2:48 PM EDT
Completed Not applicable Interventional Results available

Usability Validation of Patient Monitoring Device for Pressure Injury Prevention and Fall Detection

NCT03121144
View directory record Official record
Conditions
Pressure Ulcer, Pressure Injury, Falls Injury
Interventions
Masimo Centroid System
Device
Lead sponsor
Masimo Corporation
Industry
Eligibility
18 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated May 31, 2020 · Synced Sep 8, 2026, 2:48 PM EDT
Completed Not applicable Interventional Results available

Assessment of InfraScanner 2000™ in Detecting Subdural and Epidural Hematomas

NCT04505293
View directory record Official record
Conditions
Head Trauma, Craniocerebral Injuries, Crushing Skull Injury, Head Injuries, Head Injuries, Multiple, Head Injuries, Closed, Head Trauma,Closed, Head Trauma Injury, Head Trauma, Penetrating, Head Injury, Minor, Head Injury Major, Head Injury, Open, Injuries, Craniocerebral, Injuries, Head, Multiple Head Injury, Trauma, Head
Interventions
InfraScanner 2000™
Device
Lead sponsor
Duke University
Other
Eligibility
Not listed
Enrollment
672 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Mar 18, 2024 · Synced Sep 8, 2026, 2:48 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Pressure Injury Prevention in AE and PFC

NCT03924622
View directory record Official record
Conditions
Pressure Injury, Military Activity
Interventions
Mepilex, LiquiCell
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years to 55 Years
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2020
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated May 15, 2022 · Synced Sep 8, 2026, 2:48 PM EDT
Completed Not applicable Interventional

Evaluating Clinical Acceptance of a NPWT Wound Care System

NCT03670225
View directory record Official record
Conditions
Diabetic Foot Ulcer, Pressure Injury, Pressure Ulcer
Interventions
Invia Motion Endure
Device
Lead sponsor
Medela AG
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated Mar 19, 2020 · Synced Sep 8, 2026, 2:48 PM EDT
Completed Phase 2Phase 3 Interventional

Hyperbaric Oxygen in Lower Leg Trauma

NCT00264511
View directory record Official record
Conditions
Tibial Fracture, Soft Tissue Injury
Interventions
Hyperbaric Oxygen Treatment
Other
Lead sponsor
Bayside Health
Government
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2016
U.S. locations
1
States / cities
Concord, California
Source: ClinicalTrials.gov public record
Updated Sep 4, 2023 · Synced Sep 8, 2026, 2:48 PM EDT
Completed Phase 4 Interventional Results available

Decreasing Intraoperative Skin Damage in Prone Position Surgeries

NCT04884737
View directory record Official record
Conditions
Pressure Injury
Interventions
Mepilex Border Flex® (MBF) dressing
Other
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
107 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Santa Monica, California
Source: ClinicalTrials.gov public record
Updated May 30, 2023 · Synced Sep 8, 2026, 2:48 PM EDT
Recruiting Not applicable Interventional

Prospective Case Series Evaluating the Efficacy and Safety of NeoThelium FT for Chronic Pressure Ulcers

NCT07158658
View directory record Official record
Conditions
Pressure Injury
Interventions
NeoThelium FT (HCT/P 361)
Other
Lead sponsor
NuScience Medical Biologics, LLC
Industry
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
2
States / cities
Bossier City, Louisiana • Rayville, Louisiana
Source: ClinicalTrials.gov public record
Updated May 5, 2026 · Synced Sep 8, 2026, 2:48 PM EDT
Completed Not applicable Interventional

Pilot Testing a Patient Safety Display in the Hospital Setting

NCT03950921
View directory record Official record
Conditions
Catheter-Related Infections, Pressure Injury
Interventions
Patient Safety Display
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
132 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 31, 2019 · Synced Sep 8, 2026, 2:48 PM EDT
Completed Not applicable Interventional

Mobile and Remote Monitoring of Seating Pressure for Wheelchair Users With SCI

NCT03987243
View directory record Official record
Conditions
Spinal Cord Injuries
Interventions
Structured Pressure Ulcer Prevention Education, Mobile Seat Interface Pressure Mapping System (IPM)
Behavioral · Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 80 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 13, 2019 · Synced Sep 8, 2026, 2:48 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Diagnostic Precision and Accuracy Using the Teed Scoring System Versus the O'Neill Grading System

NCT04726306
View directory record Official record
Conditions
Otic Barotrauma, Pressure Injury, Ear Injury, Barotitis, Barotrauma
Interventions
Otic Barotrauma Grading System
Diagnostic Test
Lead sponsor
Northwell Health
Other
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Sleepy Hollow, New York
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Sep 8, 2026, 2:48 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Comparison of Sacral Interface Pressure in Healthy Volunteers on Two Dynamic Pressure-Prevention Support Surfaces

NCT06661954
View directory record Official record
Conditions
Healthy Volunteer, Pressure Distribution
Interventions
Bed A - Head of Bed 0 degrees, Bed B - Head of Bed 0 degrees, Bed A - Head of bed at 30 degrees, Bed B - head of bed at 30 degrees
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
18 Years to 89 Years
Enrollment
18 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Nov 19, 2025 · Synced Sep 8, 2026, 2:48 PM EDT
Active, not recruiting Phase 2 Interventional Accepts healthy volunteers Results available

Skin Change Actions by Nursing

NCT06127524
View directory record Official record
Conditions
Pressure Injury
Interventions
SEM Scanner
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
18 Years and older
Enrollment
4,733 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
7
States / cities
Kennett Square, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 11, 2026 · Synced Sep 8, 2026, 2:48 PM EDT
Completed Not applicable Interventional Results available

Development of Technologies to Increase In-Seat Movement to Prevent Sitting-Acquired Pressure Injuries in Wheelchair Users

NCT04934137
View directory record Official record
Conditions
Pressure Ulcer, Pressure Injury, Wheelchair
Interventions
Sensoria, AW-Shift
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
4
States / cities
Atlanta, Georgia • Minneapolis, Minnesota • Rochester, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2024 · Synced Sep 8, 2026, 2:48 PM EDT
Completed Not applicable Interventional

Effect of Rate (Slope) of Compression on the Incidence of Symptomatic ETD and MEB: a Phase III Prospective Study.

NCT04804098
View directory record Official record
Conditions
Ear Barotrauma, Middle Ear Disease, Ear Diseases, Pressure Injury, Eustachian Tube Dysfunction, Middle Ear; Injury, Middle Ear Barotrauma
Interventions
Compression Profile/Schedule: 15 minute Non-Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw), Compression Profile/Schedule: 15 minute Linear compression from start of the daily treatment until treatment pressure is reached (45 fsw)
Procedure
Lead sponsor
Northwell Health
Other
Eligibility
Not listed
Enrollment
1,553 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Sleepy Hollow, New York
Source: ClinicalTrials.gov public record
Updated Jun 8, 2026 · Synced Sep 8, 2026, 2:48 PM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Gamified Learning for Pressure Injury Prevention

NCT07028892
View directory record Official record
Conditions
Pressure Injuries, Pressure Ulcer Prevention
Interventions
A gamified mobile learning, Booklet training
Device · Other
Lead sponsor
Mehmet Akif Ersoy University
Other
Eligibility
18 Years and older
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 18, 2025 · Synced Sep 8, 2026, 2:48 PM EDT
Recruiting Not applicable Interventional

Implementing a Decision Support Tool to Prevent Community-Acquired Pressure Injury in Spinal Cord Injury (SCI) in the Spinal Cord Injury Clinic

NCT06529094
View directory record Official record
Conditions
Spinal Cord Injury, Pressure Injury
Interventions
Provider training, CAPP-FIT intervention with RA facilitation, CAPP-FIT implementation during maintenance phase
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
808 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
7
States / cities
Long Beach, California • Palo Alto, California • Tampa, Florida + 4 more
Source: ClinicalTrials.gov public record
Updated Nov 13, 2025 · Synced Sep 8, 2026, 2:48 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Onset Time of Nerve Block: A Comparison of Two Injection Locations in Patients Having Lower Leg/ Foot Surgery

NCT01542840
View directory record Official record
Conditions
Strain of Muscle and/or Tendon of Lower Leg, Fracture of Lower Leg, Crushing Injury of Lower Leg, Fracture Malunion - Ankle and/or Foot, Disorder of Joint of Ankle and/or Foot, Complete Tear, Ankle and/or Foot Ligament, Pathological Fracture - Ankle and/or Foot, Loose Body in Joint of Ankle and/or Foot
Interventions
Not listed
Lead sponsor
Ochsner Health System
Other
Eligibility
18 Years and older
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
1
States / cities
New Orleans, Louisiana
Source: ClinicalTrials.gov public record
Updated Mar 20, 2014 · Synced Sep 8, 2026, 2:48 PM EDT
Completed Not applicable Interventional

A Dual-center Study Evaluating Clinical Acceptance of a NPWT Wound Care System

NCT04593693
View directory record Official record
Conditions
Diabetic Foot Ulcer, Pressure Injury, Pressure Ulcer, Surgical Wound, Acute Wound, Traumatic Wound, Dehiscence, Edema
Interventions
Invia Motion Endure NPWT system
Device
Lead sponsor
Medela AG
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Augusta, Georgia • Austell, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 23, 2021 · Synced Sep 8, 2026, 2:48 PM EDT
Completed Not applicable Interventional Results available

Pressure Injury Prevention in the ICU With Multi-Layer Foam Dressings

NCT02962882
View directory record Official record
Conditions
Pressure Incidence Prevention
Interventions
Mepilex Border
Device
Lead sponsor
Molnlycke Health Care AB
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
2
States / cities
Anderson, South Carolina • Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Mar 25, 2018 · Synced Sep 8, 2026, 2:48 PM EDT
Terminated Phase 3 Interventional

Safety and Efficacy of Lidoderm (Lidocaine Patch 5%) in Treating Moderate to Severe Pain Associated With Carpal Tunnel Syndrome

NCT00266214
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
lidocaine patch 5%
Drug
Lead sponsor
Endo USA Inc., a Keenova Therapeutics Company
Industry
Eligibility
18 Years and older
Enrollment
210 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jun 13, 2011 · Synced Sep 8, 2026, 2:48 PM EDT