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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Cue-reactivity Clear all
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Cognitive Remediation With D-Cycloserine

NCT01399866
View directory record Official record
Conditions
Smoking Cessation
Interventions
D-cycloserine, Placebo
Drug
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2013
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 25, 2018 · Synced Jul 24, 2026, 10:07 AM EDT
Recruiting Not applicable Interventional

Cocaine Cue-reactivity Incubation Study

NCT07091877
View directory record Official record
Conditions
Cocaine Use Disorder
Interventions
Cognitive Reappraisal, Control cue-reactivity task
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 65 Years
Enrollment
252 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced Jul 24, 2026, 10:07 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Resilience to the Effects of Advertising in Children

NCT05073185
View directory record Official record
Conditions
Obesity, Childhood
Interventions
Not listed
Lead sponsor
Penn State University
Other
Eligibility
7 Years to 9 Years
Enrollment
200 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2026
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 19, 2026 · Synced Jul 24, 2026, 10:07 AM EDT
Completed Phase 1 Interventional

Alcohol and Cigarette Craving During Oxytocin Treatment

NCT04071119
View directory record Official record
Conditions
Alcohol Use Disorder, Smoking
Interventions
Oxytocin nasal spray, Placebo
Drug
Lead sponsor
Brown University
Other
Eligibility
18 Years to 55 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Jul 24, 2026, 10:07 AM EDT
Completed Phase 2 Interventional Results available

Pregnenolone and Marijuana Dependence

NCT02439814
View directory record Official record
Conditions
Marijuana Dependence
Interventions
Pregnenolone, Placebo
Drug · Other
Lead sponsor
Medical University of South Carolina
Other
Eligibility
18 Years to 65 Years
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jun 17, 2018 · Synced Jul 24, 2026, 10:07 AM EDT
Completed Phase 1Phase 2 Interventional

Novel mGluR5 Modulator Effects on Alcohol Drinking and MRI Outcomes

NCT04831684
View directory record Official record
Conditions
Alcohol Use Disorder
Interventions
Placebo, GET73
Drug
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 40 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Jul 24, 2026, 10:07 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Does Sweet Taste Potentiate Nicotine Cue Reactivity?

NCT02499757
View directory record Official record
Conditions
Healthy
Interventions
flavor and sweetener, flavor and nicotine, flavor, nicotine and sweetener, flavor
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years to 45 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Mar 8, 2020 · Synced Jul 24, 2026, 10:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Varenicline Effects on Cue Reactivity and Smoking Reward/Reinforcement

NCT00747643
View directory record Official record
Conditions
Tobacco Dependence
Interventions
varenicline, placebo
Drug
Lead sponsor
H. Lee Moffitt Cancer Center and Research Institute
Other
Eligibility
18 Years to 60 Years
Enrollment
163 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Dec 15, 2013 · Synced Jul 24, 2026, 10:07 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Evaluating Responses to Drug-Related Cues Versus Neutral Cues to Understand the Effects of Marijuana Craving - 1

NCT00218478
View directory record Official record
Conditions
Marijuana Abuse
Interventions
Cue Desensitization
Behavioral
Lead sponsor
Wayne State University
Other
Eligibility
21 Years to 45 Years
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2008
U.S. locations
1
States / cities
Detroit, Michigan
Source: ClinicalTrials.gov public record
Updated Jun 4, 2012 · Synced Jul 24, 2026, 10:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cue-based Tactile Stimulation and Infant Stress Reactivity

NCT01121523
View directory record Official record
Conditions
Premature; Infant, Light-for-dates
Interventions
Cue directed tactile stimulation
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
7 Days to 4 Months
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Oct 20, 2015 · Synced Jul 24, 2026, 10:07 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Effect of Behavioral Training on Physiological Responses to Smoking Cues, Affect and Cortisol

NCT01362101
View directory record Official record
Conditions
Smokers
Interventions
Mindfulness behavioral intervention (MT),cognitive behavioral intervention (CBT)
Behavioral
Lead sponsor
A. Eden Evins
Other
Eligibility
18 Years to 65 Years
Enrollment
56 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 10, 2013 · Synced Jul 24, 2026, 10:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Dual Use of ENDS and Combustible Cigarettes

NCT05280535
View directory record Official record
Conditions
Smoking, Cigarette, Electronic Cigarette Use
Interventions
Cue Reactivity Task, Computerized Visual Dot Probe, Choice Task
Behavioral
Lead sponsor
Brown University
Other
Eligibility
21 Years to 34 Years
Enrollment
82 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Jul 24, 2026, 10:07 AM EDT
Completed Not applicable Interventional

Brain Response to Dietary Interventions

NCT02637271
View directory record Official record
Conditions
Obesity
Interventions
Low calorie total meal replacement, Low calorie typical diet
Other
Lead sponsor
Texas Tech University
Other
Eligibility
19 Years to 60 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
Lubbock, Texas
Source: ClinicalTrials.gov public record
Updated Sep 1, 2016 · Synced Jul 24, 2026, 10:07 AM EDT
Completed Not applicable Interventional Results available

Effects of Ghrelin on Alcohol Cue Reactivity and Craving

NCT01190085
View directory record Official record
Conditions
Alcoholism
Interventions
Ghrelin, Saline solution
Drug
Lead sponsor
Brown University
Other
Eligibility
18 Years to 70 Years
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2011
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated May 14, 2014 · Synced Jul 24, 2026, 10:07 AM EDT
Withdrawn Phase 1 Interventional Accepts healthy volunteers

Concurrent PET D2/D3 Receptor Imaging and fMRI Smoking Cue Reactivity in Smokers

NCT01784016
View directory record Official record
Conditions
Nicotine Dependence, Smoking Cue Reactivity, Relapse to Smoking
Interventions
[11C]-PHNO
Radiation
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 50 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
3
States / cities
Belmont, Massachusetts • Boston, Massachusetts • Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 22, 2014 · Synced Jul 24, 2026, 10:07 AM EDT
Completed Early Phase 1 Interventional Accepts healthy volunteers

Cortical rTMS as a Tool to Change Brain Reactivity to Alcohol Cues

NCT02939313
View directory record Official record
Conditions
Alcohol Dependance
Interventions
medial prefrontal cortex, dorsolateral prefrontal cortex, sham
Device
Lead sponsor
Medical University of South Carolina
Other
Eligibility
21 Years to 40 Years
Enrollment
71 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated Jan 12, 2022 · Synced Jul 24, 2026, 10:07 AM EDT
Active, not recruiting Not applicable Interventional

Electronic Cigarettes and Reactivity to Smoking Cues

NCT01782599
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Dual nicotine patch and electronic cigarette
Other
Lead sponsor
Mclean Hospital
Other
Eligibility
18 Years to 45 Years
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2027
U.S. locations
1
States / cities
Belmont, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Jul 24, 2026, 10:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The Effect of Exercise on Acute Nicotine Withdrawal

NCT01047930
View directory record Official record
Conditions
Nicotine Dependence, Smoking, Sleep Disorders, Intrinsic
Interventions
Exercise
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years to 45 Years
Enrollment
88 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2013
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 1, 2014 · Synced Jul 24, 2026, 10:07 AM EDT
Not yet recruiting Not applicable Interventional Accepts healthy volunteers

Development of an Eating Behavior Risk Score

NCT07266506
View directory record Official record
Conditions
Obesity, Childhood
Interventions
Assessment of PACE Eating Phenotype and Related Behavioral and Neurobiological Measures
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
7 Years to 9 Years
Enrollment
420 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2032
U.S. locations
1
States / cities
State College, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Dec 4, 2025 · Synced Jul 24, 2026, 10:07 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Study of Brain, Reward, and Kids' Eating

NCT05456516
View directory record Official record
Conditions
Obesity, Childhood, Eating Behavior
Interventions
Food Rating
Behavioral
Lead sponsor
Penn State University
Other
Eligibility
8 Years to 10 Years
Enrollment
76 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 12, 2026 · Synced Jul 24, 2026, 10:07 AM EDT
Completed Not applicable Interventional

Effect of Music on Cue Reactivity for Patients With Opioid Use Disorder

NCT06948890
View directory record Official record
Conditions
Opioid Use Disorder
Interventions
Music intervention, Silence
Other
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 3, 2026 · Synced Jul 24, 2026, 10:07 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Brain/Craving Response to Smoking Cues After Oral Nicotine Pouch Use

NCT07698470
View directory record Official record
Conditions
Nicotine Dependence
Interventions
Oral Nicotine Pouch, Smoking Cue Reactivity Task
Other · Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
21 Years to 55 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 12, 2026 · Synced Jul 24, 2026, 10:07 AM EDT
Completed Not applicable Interventional Results available

Effect of Theta Burst Stimulation on Alcohol Cue Reactivity

NCT04223154
View directory record Official record
Conditions
Alcohol Drinking, Alcohol Use Disorder, Trauma Injury, Alcohol Dependence, Alcohol Abuse
Interventions
Real iTBS to the dlPFC, Sham iTBS to the dlPFC
Device
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
21 Years to 65 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 18, 2023 · Synced Jul 24, 2026, 10:07 AM EDT
Completed Phase 4 Interventional Results available

Neurobehavioral Substrates of Propranolol's Effects on Drug Cue Reactivity

NCT03309943
View directory record Official record
Conditions
Cigarette Smoking
Interventions
Propranolol, Placebo
Drug
Lead sponsor
Duke University
Other
Eligibility
18 Years to 55 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 12, 2020 · Synced Jul 24, 2026, 10:07 AM EDT