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Showing 1–24 of 122 matching trials from the live ClinicalTrials.gov search.
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Completed Not applicable Interventional

Ultrasound Guided - Incisionless Threaded Carpal Tunnel Release

NCT04101955
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Incisionless Threaded Carpal Tunnel, Standard Mini-Open Carpal Tunnel
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 21, 2025 · Synced Jul 21, 2026, 5:31 PM EDT
Withdrawn Phase 4 Interventional

SPY Angiography To Assist With Ulnar Nerve Transposition at the Elbow

NCT05332405
View directory record Official record
Conditions
Cubital Tunnel Syndrome
Interventions
Indocyanine green
Drug
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 28, 2023 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional

Patient Outcomes With Endoscopic Versus Open Carpal Tunnel Release

NCT00880295
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
endoscopic carpal tunnel release, open carpal tunnel release
Procedure
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 75 Years
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2016
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 23, 2017 · Synced Jul 21, 2026, 5:31 PM EDT
Not listed Phase 2 Interventional

Influence of Pronator Teres Release on Treatment of Median Nerve Compression Neuropathy

NCT01562860
View directory record Official record
Conditions
Median Nerve Compression
Interventions
Pronator Teres Release, dual compression release, median nerve release only
Procedure
Lead sponsor
Christine M. Kleinert Institute for Hand and Microsurgery
Other
Eligibility
18 Years to 65 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2019
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Jan 24, 2018 · Synced Jul 21, 2026, 5:31 PM EDT
Not yet recruiting Not applicable Interventional

Understanding Patient Preferences When Deciding on a Voluntary Musculoskeletal Test

NCT07158892
View directory record Official record
Conditions
Non-traumatic Musculoskeletal Conditions, Carpal Tunnel Syndrome (CTS), Lateral Epicondylitis, Osteoarthritis, Trigger Digit, Dupuytren Contracture, Rotator Cuff Tendinopathy, De Quervain Disease
Interventions
Diagnostic Advance Care Planning Discussion, Informational Statement Only
Behavioral
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Sep 7, 2025 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Does Adding Lidocaine to Corticosteroid Injections Reduce Pain Intensity in Hand Surgery

NCT06188221
View directory record Official record
Conditions
Hand Osteoarthritis, Trigger Finger, Carpal Tunnel Syndrome
Interventions
Lidocaine, Corticoids
Drug
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 89 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2023
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jan 2, 2024 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Impact of OnabotulinumtoxinA (BOTOX®) on Stress

NCT06778421
View directory record Official record
Conditions
Stress (Psychology), Stress, Healthy Adult Female Participants, Stress, Psychologic, Stress, Psychological Cumulative, Stress, Physiological, Stress Response, Stress Levels, Stress Perception
Interventions
Intramuscular injection, OnabotulinumtoxinA (Botox®) Injections, Sodium Chloride
Procedure · Drug · Other
Lead sponsor
Center for Advanced Facial Plastic Surgery
Other
Eligibility
18 Years to 65 Years · Female only
Enrollment
4 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Beverly Hills, California
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Jul 21, 2026, 5:31 PM EDT
Suspended Not applicable Interventional

Posture Correction in Cubital Tunnel Syndrome

NCT06095011
View directory record Official record
Conditions
Cubital Tunnel Syndrome
Interventions
UpRight Go
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The BSHAPE Intervention Program for Safety and Health of Survivors of Cumulative Trauma

NCT03664362
View directory record Official record
Conditions
Violence, Cumulative Trauma, HIV Risk, Stress, Mental Health, Reproductive Health, Empowerment
Interventions
The BSHAPE Intervention
Behavioral
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 55 Years · Female only
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 25, 2023 · Synced Jul 21, 2026, 5:31 PM EDT
Withdrawn Not applicable Interventional

Randomized Trial of Supercharged End-to-Side Anterior Interosseous Nerve Transfer for Severe Cubital Tunnel Syndrome

NCT04647058
View directory record Official record
Conditions
Cubital Tunnel Syndrome, Ulnar Nerve Compression, Ulnar Nerve Palsy, Ulnar Nerve Entrapment, Ulnar Nerve Entrapment at Elbow, Ulnar Nerve Entrapment Syndrome, Ulnar Neuropathies, Ulnar Claw
Interventions
Cubital tunnel release, Supercharged end-to-side (SETS) nerve transfer
Procedure
Lead sponsor
Brigham and Women's Hospital
Other
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 9, 2022 · Synced Jul 21, 2026, 5:31 PM EDT
Terminated Not applicable Interventional

The Effect of Surgical Incision Size on Carpal Tunnel Surgery

NCT00435071
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Carpal tunnel release surgery
Procedure
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2008
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 17, 2011 · Synced Jul 21, 2026, 5:31 PM EDT
Terminated Not applicable Interventional

Evaluation of the MANOS Carpal Tunnel Release System in Patients With Carpal Tunnel Syndrome

NCT01450735
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
MANOS CTR™
Device
Lead sponsor
Thayer Intellectual Property, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2012
U.S. locations
3
States / cities
Hayward, California • San Francisco, California • Willits, California
Source: ClinicalTrials.gov public record
Updated Jan 14, 2013 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Phase 2 Interventional

Sham Device, Pill Placebo or Treatment For Arm Pain

NCT00029497
View directory record Official record
Conditions
Cumulative Trauma Disorders, Repetitive Strain Injury, Carpal Tunnel Syndrome, Pain
Interventions
Acupuncture, Amitriptyline
Procedure · Drug
Lead sponsor
National Center for Complementary and Integrative Health (NCCIH)
NIH
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Ends 2004
U.S. locations
2
States / cities
Boston, Massachusetts • Cambridge, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 21, 2013 · Synced Jul 21, 2026, 5:31 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Research Protocol for Karuna Labs Inc.: Safety and Efficacy of Virtual Reality Graded Motor Imagery for Chronic Pain

NCT04060875
View directory record Official record
Conditions
Chronic Pain, Low Back Pain, Fibromyalgia, Upper Extremity Dysfunction, Complex Regional Pain Syndromes, Phantom Limb Pain, Rheumatoid Arthritis, Carpal Tunnel Syndrome, Repetitive Strain Injury
Interventions
Karuna Labs Virtual Reality Software
Device
Lead sponsor
Karuna Labs Inc.
Industry
Eligibility
18 Years to 70 Years
Enrollment
24 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jun 10, 2021 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional

Effect of Lumbrical Stretching on Carpal Tunnel Syndrome

NCT00803257
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Lumbrical splint and Lumbrical exercises
Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
124 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2011
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jun 12, 2012 · Synced Jul 21, 2026, 5:31 PM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Wound Closure Study in Carpal Tunnel and Trigger Finger Surgery

NCT03781141
View directory record Official record
Conditions
Carpal Tunnel Syndrome, Trigger Finger
Interventions
Wound closure
Procedure
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Jul 21, 2026, 5:31 PM EDT
Not listed Phase 4 Interventional

A Comparison of Ultrasound-guided Steroid Injection With Wrist Splint in Carpal Tunnel Syndrome

NCT04515966
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Methylprednisolone Injection [Solu-Medrol], wrist splint
Drug · Device
Lead sponsor
Mercy Health Ohio
Other
Eligibility
18 Years to 75 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Boardman, Ohio
Source: ClinicalTrials.gov public record
Updated Sep 8, 2021 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Phase 4 Interventional Results available

Preoperative Antibiotics for Carpal Tunnel Release Surgery

NCT03432858
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Vancomycin, Cefazolin, Saline Solution
Drug
Lead sponsor
WellSpan Health
Other
Eligibility
18 Years and older
Enrollment
184 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
1
States / cities
York, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Nov 9, 2021 · Synced Jul 21, 2026, 5:31 PM EDT
Terminated No phase listed Observational

Corticosteroid Injection as a Predictor of Outcome in Carpal Tunnel Release

NCT00655915
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Corticosteroid Injection- 1ml of Betamethasone and 1 ml of 1% Lidocaine
Other
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years and older
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2011
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Mar 8, 2011 · Synced Jul 21, 2026, 5:31 PM EDT
Terminated Not applicable Interventional

Comparative Study of Two Incision vs. Mini Open Carpal Tunnel Release

NCT05325567
View directory record Official record
Conditions
Carpal Tunnel Syndrome
Interventions
Mini open incision CTR
Procedure
Lead sponsor
University of Louisville
Other
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 17, 2023 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Safety Study to Evaluate the Cumulative Irritation Potential of Topically Applied ZuraPrep™ and ZuraPrep™ Without IPA

NCT02160574
View directory record Official record
Conditions
Surgical Site Infection
Interventions
ChloraPrep, 0.1% Sodium Lauryl Sulfate, 0.9% Physiological Saline, ZuraPrep without IPA
Drug · Other
Lead sponsor
Zurex Pharma, Inc.
Industry
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014
U.S. locations
1
States / cities
Bozeman, Montana
Source: ClinicalTrials.gov public record
Updated Oct 26, 2014 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Nylon Versus Chromic Gut Sutures for Minor Hand Surgery

NCT03407820
View directory record Official record
Conditions
All Minor Hand Surgery Including, Carpal Tunnel Syndrome, Trigger Finger, Ganglion Cysts, De Quervain Syndrome, Dupuytren Contracture
Interventions
Absorbable Chromic gut sutures, Non-absorbable Nylon sutures
Procedure
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years to 89 Years
Enrollment
112 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
3
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Jul 30, 2025 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Phase 4 Interventional

A Study Of Lidocaine Patch 5% Alone, Gabapentin Alone, And Lidocaine Patch 5% And Gabapentin In Combination For The Relief Of Pain In Patients With Diverse Peripheral Neuropathic Pain Conditions

NCT00904202
View directory record Official record
Conditions
Postherpetic Neuralgia, Diabetic Neuropathy, Complex Regional Pain Syndrome, Carpal Tunnel Syndrome, HIV Neuropathy, Idiopathic Sensory Neuropathy, Peripheral Neuropathy
Interventions
Placebo Capsules + Placebo Patch, Placebo capsules + Lidoderm®, Gabapentin + Placebo, Gabapentin + Lidoderm®, Gabapentin 300 mg capsules 1800 mg/day + placebo patch, Gabapentin 1800 mg/day + Lidoderm patch
Drug
Lead sponsor
Endo USA Inc., a Keenova Therapeutics Company
Industry
Eligibility
18 Years and older
Enrollment
62 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2003
U.S. locations
7
States / cities
Birmingham, Alabama • Hueytown, Alabama • Phoenix, Arizona + 4 more
Source: ClinicalTrials.gov public record
Updated Jan 1, 2024 · Synced Jul 21, 2026, 5:31 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Strength Training on Musculoskeletal Overuse Injuries in Female Runners

NCT03080246
View directory record Official record
Conditions
Overuse Injury
Interventions
Strength Training Exercise
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
18 Years to 60 Years · Female only
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2019
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Source: ClinicalTrials.gov public record
Updated May 11, 2020 · Synced Jul 21, 2026, 5:31 PM EDT