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ClinicalTrials.gov public records Last synced Jul 23, 2026, 7:38 AM EDT

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Showing 1–5 of 5 matching trials from the live ClinicalTrials.gov search.
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Conditions
Décolleté Wrinkles
Interventions
Octave-Ultherapy treatment
Device
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
35 Years to 65 Years · Female only
Enrollment
99 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
10
States / cities
Beverly Hills, California • San Mateo, California • Norwalk, Connecticut + 6 more
Conditions
Skin Roughness, Wrinkle, Fine Lines, Skin Thickness
Interventions
KB301, Placebo
Biological · Other
Lead sponsor
Krystal Biotech, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
85 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2029
U.S. locations
4
States / cities
Campbell, California • Newport Beach, California • Rancho Santa Margarita, California + 1 more
Conditions
Décolleté Wrinkles
Interventions
Radiesse
Device
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
40 Years to 65 Years · Female only
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Alpharetta, Georgia
Conditions
Décolleté Wrinkles
Interventions
Treatment with diluted Radiesse
Device
Lead sponsor
Merz North America, Inc.
Industry
Eligibility
30 Years to 65 Years · Female only
Enrollment
152 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2025
U.S. locations
9
States / cities
Beverly Hills, California • Redondo Beach, California • San Diego, California + 6 more
Active, not recruiting Phase 1Phase 2 Interventional Accepts healthy volunteers

A Study Assessing KB304 for the Treatment of Wrinkles in Women

NCT06724900
Conditions
Wrinkles in Decolletage, Pigmentation, Décolleté Wrinkles
Interventions
KB304, 0.9% Normal Saline (NS)
Biological · Drug
Lead sponsor
Krystal Biotech, Inc.
Industry
Eligibility
18 Years to 75 Years · Female only
Enrollment
19 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Newport Beach, California