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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: DBS Clear all
Completed No phase listed Observational Accepts healthy volunteers

Insights Into Deep Brain Stimulation (DBS) for Cervical Dystonia

NCT01671527
View directory record Official record
Conditions
Cervical Dystonia
Interventions
Transcranial magnetic stimulation (TMS)
Procedure
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jun 12, 2016 · Synced Sep 12, 2026, 1:24 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Ventrointermediate Nucleus (VIM DBS) and Working Memory

NCT00906412
View directory record Official record
Conditions
Essential Tremor
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
40 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2016
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 9, 2016 · Synced Sep 12, 2026, 1:24 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Temporal Interference Methods for Non-invasive Deep Brain Stimulation, Study 1.3

NCT07594795
View directory record Official record
Conditions
Healthy Volunteers
Interventions
Temporal Interference (TI) Electrical Stimulation - dACC 20 Hz TI Active, Temporal Interference (TI) Electrical Stimulation - dACC 20 Hz TI Sham, Temporal Interference (TI) Electrical Stimulation - dACC Comparison Frequency TI Active, Temporal Interference (TI) Electrical Stimulation - dACC Comparison Frequency TI Sham
Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 50 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
1
States / cities
Bloomington, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 10, 2026 · Synced Sep 12, 2026, 1:24 PM EDT
Recruiting Not applicable Interventional

Interposed Nucleus aDBS for Ataxia

NCT07325487
View directory record Official record
Conditions
Spinocerebellar Ataxia (SCA), Spinocerebellar Ataxia Type 6
Interventions
Deep Brain Stimulation
Device
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 89 Years
Enrollment
5 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2031
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 12, 2026, 1:24 PM EDT
Recruiting Phase 2Phase 3 Interventional

A Study of Buntanetap in Participants With PD

NCT07284784
View directory record Official record
Conditions
Parkinson's Disease (PD), Deep Brain Stimulation
Interventions
buntanetap/posiphen
Drug
Lead sponsor
Annovis Bio Inc.
Industry
Eligibility
40 Years to 85 Years
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
27
States / cities
Birmingham, Alabama • Sun City, Arizona • Fountain Valley, California + 24 more
Source: ClinicalTrials.gov public record
Updated Jul 20, 2026 · Synced Sep 12, 2026, 1:24 PM EDT
Active, not recruiting Not applicable Interventional

Combined Cortical/Subcortical Recording and Stimulation as a Circuit-Oriented Treatment for Obsessive-Compulsive Disorder

NCT03184454
View directory record Official record
Conditions
Obsessive Compulsive Disorder
Interventions
Medtronic Percept Deep Brain Stimulation
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
21 Years to 65 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
2
States / cities
Charlestown, Massachusetts • Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Dec 18, 2025 · Synced Sep 12, 2026, 1:24 PM EDT
Completed Not applicable Interventional Results available

Low Frequency Subthalamic Nucleus Deep Brain Stimulation to Improve Verbal Fluency

NCT04383665
View directory record Official record
Conditions
Parkinson Disease
Interventions
STN DBS 10Hz, STN DBS 130Hz, STN DBS off
Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Jul 14, 2021 · Synced Sep 12, 2026, 1:24 PM EDT
Completed No phase listed Observational

Deep Brain Stimulation of the Subthalamic Nucleus (STN) and Cognitive Control

NCT00917722
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Not listed
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Not listed
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2013
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Nov 9, 2016 · Synced Sep 12, 2026, 1:24 PM EDT
Completed Not applicable Interventional

Effect of Deep Brain Stimulation (DBS) on Sleep Architecture in Patients With Movement Disorders

NCT01169324
View directory record Official record
Conditions
Parkinson's Disease, Tremor, Dystonia
Interventions
Alteration of DBS stimulator settings
Other
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2015
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 25, 2019 · Synced Sep 12, 2026, 1:24 PM EDT
Not listed Not applicable Interventional

Evaluation of a Decision Aid for Deep Brain Stimulation Surgery for Parkinson's Disease

NCT06446505
View directory record Official record
Conditions
Parkinson Disease
Interventions
Deep Brain Stimulation Decision Aid
Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
42 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jun 5, 2024 · Synced Sep 12, 2026, 1:24 PM EDT
Completed No phase listed Observational Results available

IPG Replacement Study (PREFERENCE-H)

NCT02963259
View directory record Official record
Conditions
Parkinson Disease
Interventions
SJM Infinity™ DBS IPG or SJM Brio™ DBS IPG system
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years to 74 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
3
States / cities
Kendall, Florida • Miami, Florida • Albany, New York
Source: ClinicalTrials.gov public record
Updated Jul 7, 2024 · Synced Sep 12, 2026, 1:24 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Development of Adaptive Deep Brain Stimulation for OCD

NCT04281134
View directory record Official record
Conditions
Obsessive-Compulsive Disorder
Interventions
Summit RC+S System, One Month Blinded Discontinuation Period:
Device · Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
21 Years to 70 Years
Enrollment
3 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2027
U.S. locations
3
States / cities
Pittsburgh, Pennsylvania • Providence, Rhode Island • Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 26, 2026 · Synced Sep 12, 2026, 1:24 PM EDT
Terminated No phase listed Observational

Apraxia in Parkinson's Disease Patients With Deep Brain Stimulation

NCT04725773
View directory record Official record
Conditions
Deep Brain Stimulation, Parkinson Disease, Apraxia, Motor
Interventions
Deep brain stimulation effect on apraxia
Device
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 80 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Jul 15, 2025 · Synced Sep 12, 2026, 1:24 PM EDT
Not listed No phase listed Observational

Subthalamic Nucleus Deep Brain Stimulation in Speech Study

NCT05493670
View directory record Official record
Conditions
Parkinson Disease, Dysarthria
Interventions
Not listed
Lead sponsor
Jeremy Greenlee
Other
Eligibility
21 Years to 84 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Dec 21, 2023 · Synced Sep 12, 2026, 1:24 PM EDT
Active, not recruiting Not applicable Interventional

DBS for TRD With the Medtronic Summit RC+S

NCT04106466
View directory record Official record
Conditions
Major Depressive Disorder, Treatment Resistant Depression
Interventions
Medtronic Summit RC+S DBS system
Device
Lead sponsor
Helen Mayberg, MD
Other
Eligibility
25 Years to 70 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2030
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 21, 2026 · Synced Sep 12, 2026, 1:24 PM EDT
Recruiting No phase listed Observational

Registry of Deep Brain Stimulation With the VERCISE™ System: Vercise DBS Registry

NCT02071134
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Deep Brain Stimulation (DBS)
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2038
U.S. locations
28
States / cities
Aliso Viejo, California • Los Angeles, California • Aurora, Colorado + 25 more
Source: ClinicalTrials.gov public record
Updated Aug 10, 2026 · Synced Sep 12, 2026, 1:24 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Cortical Network Modulation by Subthalamic Nucleus DBS

NCT04922411
View directory record Official record
Conditions
Parkinson Disease, Deep Brain Stimulation
Interventions
STN DBS
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
25 Years to 75 Years
Enrollment
49 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2025
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Dec 17, 2025 · Synced Sep 12, 2026, 1:24 PM EDT
Recruiting No phase listed Observational

Clinical Outcomes for Deep Brain Stimulation

NCT03992625
View directory record Official record
Conditions
Parkinson Disease, Essential Tremor, Dystonia
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Washington University School of Medicine
Other
Eligibility
Not listed
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2030
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 19, 2019 · Synced Sep 12, 2026, 1:24 PM EDT
Completed No phase listed Observational

DiSCERN: Advanced PD Therapy Candidacy and Evaluation System

NCT05351580
View directory record Official record
Conditions
Parkinson Disease
Interventions
DiSCERN
Device
Lead sponsor
Great Lakes NeuroTechnologies Inc.
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
2
States / cities
Cincinnati, Ohio • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 25, 2025 · Synced Sep 12, 2026, 1:24 PM EDT
Active, not recruiting Not applicable Interventional

Low Intensity Focused Ultrasound for Mild Cognitive Impairment and Mild Alzheimer's Disease

NCT05417555
View directory record Official record
Conditions
Mild Cognitive Impairment, Amnestic Mild Cognitive Disorder, Deep Brain Stimulation, Mild Alzheimer's Disease
Interventions
Low-Intensity Focused Ultrasound Pulsation (LIFUP)
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
50 Years to 90 Years
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Aug 18, 2026 · Synced Sep 12, 2026, 1:24 PM EDT
Recruiting Phase 1 Interventional

A Study to Evaluate Feasibility, Safety, and Clinical Responses of Implanting Autologous Peripheral Nerve Tissue Into the Brain for Non-motor or Motor Symptoms in Patients With Parkinson's Disease Undergoing DBS Surgery

NCT06683378
View directory record Official record
Conditions
Parkinson's Disease
Interventions
Reparative Autologous peripheral nerve tissue
Procedure
Lead sponsor
Craig van Horne, MD, PhD
Other
Eligibility
45 Years to 75 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Aug 30, 2026 · Synced Sep 12, 2026, 1:24 PM EDT
Recruiting No phase listed Observational

Deep Brain Stimulation (DBS) Retrospective Outcomes Study

NCT03664609
View directory record Official record
Conditions
Parkinson Disease, Essential Tremor, Dystonia
Interventions
Deep Brain Stimulation
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
Not listed
Enrollment
5,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2028
U.S. locations
10
States / cities
Phoenix, Arizona • Moreno Valley, California • San Francisco, California + 7 more
Source: ClinicalTrials.gov public record
Updated Sep 2, 2026 · Synced Sep 12, 2026, 1:24 PM EDT
Enrolling by invitation Not applicable Interventional Accepts healthy volunteers

Mid-frontal Delta/Theta and Cognitive Control

NCT06984757
View directory record Official record
Conditions
Parkinson&Amp;Amp;#39;s Disease (PD)
Interventions
Deep-brain Stimulation, Transcranial Magnetic Stimulation, Transcranial Alternating Current Stimulation
Device
Lead sponsor
Nandakumar Narayanan
Other
Eligibility
18 Years to 99 Years
Enrollment
635 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2029
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Sep 12, 2026, 1:24 PM EDT
Completed Phase 2 Interventional

Deep Brain Stimulation for Cervical Dystonia

NCT00105430
View directory record Official record
Conditions
Dystonia, Generalized Primary Dystonia
Interventions
Deep Brain Stimulation
Procedure
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
7 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 5, 2006 · Synced Sep 12, 2026, 1:24 PM EDT