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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Conditions
Covid19
Interventions
SARS-CoV-2 mRNA vaccine
Biological
Lead sponsor
TruDiagnostic
Industry
Eligibility
18 Years and older
Enrollment
60 participants
Timeline
2021 – 2022
U.S. locations
1
States / cities
Lexington, Kentucky
Completed Not applicable Interventional Accepts healthy volunteers

Folic Acid Supplementation in Women of Child Bearing Age

NCT01841658
Conditions
Obesity
Interventions
Folic acid
Dietary Supplement
Lead sponsor
University of Georgia
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2013 – 2016
U.S. locations
1
States / cities
Athens, Georgia
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Novel Biomarkers in the Neoplastic Progression of Barrett's Esophagus

NCT00431756
Conditions
Barrett Esophagus, Esophageal Neoplasm, Gastroesophageal Reflux
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 95 Years
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2002 – 2026
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Neoplasms, Solid Tumors
Interventions
TdCyd
Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 120 Years
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2025
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Unspecified Adult Solid Tumor, Protocol Specific
Interventions
peginterferon alfa-2b, decitabine, laboratory biomarker analysis
Biological · Drug · Other
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2009
U.S. locations
1
States / cities
Las Vegas, Nevada
Conditions
HIV Infection
Interventions
exercise training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years and older
Enrollment
89 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
3
States / cities
Decatur, Georgia • Baltimore, Maryland • Salem, Virginia
Conditions
Gastric Cancer, Non-Atrophic Gastritis, Intestinal Metaplasia
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
30 Years to 70 Years
Enrollment
1,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
7
States / cities
Batesville, Arkansas • Stanford, California • Athens, Georgia + 4 more
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

Methylation Diet and Lifestyle Study

NCT03472820
Conditions
Lifestyle, Diet, Healthy
Interventions
Diet Recommendations, Lifestyle Recommendations, Exercise Recommendations, Stress Management Recommendations, PhytoGanix (tropical fruit flavor), UltraFlora Intensive Care
Other
Lead sponsor
National University of Natural Medicine
Other
Eligibility
50 Years to 72 Years · Male only
Enrollment
44 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2024
U.S. locations
1
States / cities
Portland, Oregon
Conditions
Neoplasms, Solid Tumors
Interventions
aza-TdC
Drug
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 120 Years
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2026
U.S. locations
1
States / cities
Bethesda, Maryland
Conditions
Small Cell Lung Cancer, Large Cell Neuroendocrine (NE) Tumors, Treatment Failure, Biomarkers / Blood, Biomarkers, Immunotherapy
Interventions
Carboplatin/Cisplatin -Etoposide - Atezolizumab
Drug
Lead sponsor
Oncology Center of Biochemical Education And Research
Other
Eligibility
18 Years to 85 Years
Enrollment
111 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
1
States / cities
New York, New York
Completed Not applicable Interventional Results available

Nuts and Oil Pilot Study

NCT04361617
Conditions
Metabolic Syndrome
Interventions
Daily consumption of tree nuts and extra virgin olive oil
Behavioral
Lead sponsor
Wake Forest University Health Sciences
Other
Eligibility
35 Years and older
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Winston-Salem, North Carolina
Completed Phase 4 Interventional Accepts healthy volunteers

Effects of Tildrakizumab on Epigenetic Age

NCT05110313
Conditions
Psoriasis, Aging, Epigenetic Disorder, Inflammation; Skin
Interventions
TILDRAKIZUMAB
Biological
Lead sponsor
Carlos Wambier
Other
Eligibility
35 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Providence, Rhode Island
Conditions
Glioblastoma (GBM)
Interventions
BGB-58067
Drug
Lead sponsor
Nader Sanai
Other
Eligibility
18 Years and older
Enrollment
78 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Phoenix, Arizona
Conditions
Stomach Cancer, Gastric Cancer
Interventions
Not listed
Lead sponsor
National Cancer Institute (NCI)
NIH
Eligibility
18 Years to 100 Years
Enrollment
440 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
Bethesda, Maryland
Completed Not applicable Interventional Accepts healthy volunteers Results available

A Randomized Controlled Trial to Improve Mother-Infant Synchrony Among Women With Childhood Adversity

NCT04818112
Conditions
Parent-Child Relations, Maternal Behavior, Infant Behavior
Interventions
ATVV, Attention control
Behavioral
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older · Female only
Enrollment
262 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2024
U.S. locations
2
States / cities
Tucson, Arizona
Recruiting No phase listed Observational Accepts healthy volunteers

Identification and Validation of Epigenetic Biomarkers of PMDD

NCT06771583
Conditions
PMDD, Premenstrual Dysphoric Disorder (PMDD), Premenstrual Syndrome-PMS, Premenstrual Syndrome, Menstrual Cycle
Interventions
Not listed
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 50 Years · Female only
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2031
U.S. locations
1
States / cities
Baltimore, Maryland
Conditions
Aging, Mobility Disability
Interventions
Progressive Resistance Training, Health Education
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
65 Years and older
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2030
U.S. locations
2
States / cities
Boston, Massachusetts • Rochester, Minnesota
Completed No phase listed Observational Accepts healthy volunteers

Liquid Biopsy for Early Non-small Lung Cancer Detection

NCT05462795
Conditions
Non Small-cell Lung Cancer
Interventions
Liquid biopsy for aberrant DNA methylation analysis - Indeterminate pulmonary nodule, Liquid biopsy for aberrant DNA methylation analysis - Known lung cancer for surgical resection, Liquid biopsy for aberrant DNA methylation analysis - Healthy volunteer, Liquid biopsy for aberrant DNA methylation analysis - Benign lung disease
Diagnostic Test
Lead sponsor
University of Arizona
Other
Eligibility
18 Years and older
Enrollment
171 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Tucson, Arizona
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Epigenetic Signature for CRC Early Detection

NCT07224854
Conditions
Colorectal Cancer (Diagnosis), Non-cancer Controls, DNA Methylation, Cell Free DNA, Early Detection of Cancer
Interventions
Not listed
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Monrovia, California
Completed Not applicable Interventional Accepts healthy volunteers

Folic Acid Supplementation in Pregnant Women: Dose Response

NCT02124642
Conditions
Pregnancy
Interventions
Folic acid, 400 mcg/day, Folic acid 800 mcg/day
Dietary Supplement
Lead sponsor
University of Georgia
Other
Eligibility
18 Years to 40 Years · Female only
Enrollment
51 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2017
U.S. locations
1
States / cities
Athens, Georgia
Conditions
Colorectal Cancer, Colorectal Adenocarcinoma, Colorectal Cancer Stage II, Colorectal Cancer Stage III, Colorectal Cancer Recurrent
Interventions
CENSURE
Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Monrovia, California
Conditions
Cancer
Interventions
Decitabine and Pegylated Interferon-Alfa 2B
Drug
Lead sponsor
Nevada Cancer Institute
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
1
States / cities
Las Vegas, Nevada
Recruiting Not applicable Interventional Accepts healthy volunteers

DNA Methylation and Vascular Function

NCT03527420
Conditions
Obesity, Vascular Dysfunction
Interventions
Exercise training
Other
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
18 Years to 50 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Conditions
Neoplasms
Interventions
5-Fluoro-2-Deoxycytidine (FdCyd), Laboratory Biomarker Analysis, Pharmacological Study, Tetrahydrouridine (THU)
Drug · Other
Lead sponsor
City of Hope Medical Center
Other
Eligibility
18 Years and older
Enrollment
58 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2012
U.S. locations
4
States / cities
Duarte, California • Los Angeles, California • Sacramento, California + 1 more