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ClinicalTrials.gov public records Last synced Oct 21, 2026, 11:24 AM EDT

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Showing 1–24 of 562 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Deafness Clear all
Withdrawn Phase 2 Interventional Accepts healthy volunteers

A Phase 2b Study of SPI-1005 to Prevent Acute Noise Induced Hearing Loss

NCT02779192
View directory record Official record
Conditions
Noise Induced Hearing Loss
Interventions
SPI-1005 200mg, SPI-1005 400mg, Placebo
Drug
Lead sponsor
Sound Pharmaceuticals, Incorporated
Industry
Eligibility
18 Years to 50 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2026
U.S. locations
5
States / cities
Miami, Florida • Kansas City, Kansas • Charleston, South Carolina + 2 more
Source: ClinicalTrials.gov public record
Updated Jun 3, 2026 · Synced Oct 21, 2026, 11:24 AM EDT
Recruiting Early Phase 1 Interventional Accepts healthy volunteers

Vocal Emotion Communication With Cochlear Implants

NCT05486637
View directory record Official record
Conditions
Cochlear Hearing Loss
Interventions
Perception of acoustic cues to emotion, Production of acoustic cues to emotion
Behavioral
Lead sponsor
Father Flanagan's Boys' Home
Other
Eligibility
6 Years to 80 Years
Enrollment
255 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
4
States / cities
Tempe, Arizona • Los Angeles, California • Evanston, Illinois + 1 more
Source: ClinicalTrials.gov public record
Updated Sep 19, 2025 · Synced Oct 21, 2026, 11:24 AM EDT
Not yet recruiting Phase 1Phase 2 Interventional

A Basket Clinical Study to Assess Glycerol Tributyrate in Patients With Mitochondrial Encephalopathy, Lactic Acidosis, Stroke-like Episodes (MELAS) or Leber's Hereditary Optic Neuropathy-Plus (LHON-Plus)

NCT06792500
View directory record Official record
Conditions
MELAS Syndrome, Lebers Hereditory Optic Neuropathy With Extra Ocular Symptoms (LHON-Plus)
Interventions
Glycerol Tributyrate
Drug
Lead sponsor
George Washington University
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2027 – 2028
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Oct 5, 2026 · Synced Oct 21, 2026, 11:24 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

RoboHear™ Device: Advanced Haptic Technology That Allows the Deaf to Understand Speech

NCT03966144
View directory record Official record
Conditions
Hearing Impairment, Deafness
Interventions
RoboHear Device
Device
Lead sponsor
University of Arkansas
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2020
U.S. locations
1
States / cities
Little Rock, Arkansas
Source: ClinicalTrials.gov public record
Updated May 20, 2020 · Synced Oct 21, 2026, 11:24 AM EDT
Not listed Not applicable Interventional

Hear Me Read 2021 Clinical Trial

NCT05245799
View directory record Official record
Conditions
Hearing Loss, Deafness, Hearing Disorders in Children, Hearing Impaired Children, Speech Therapy, Speech Disorders in Children, Literacy
Interventions
Speech Language Therapy, Digital Software Application
Behavioral
Lead sponsor
Prasanth Pattisapu
Other
Eligibility
3 Years to 5 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 30, 2023 · Synced Oct 21, 2026, 11:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Test of Hearing Health Education Programs for Farm and Rural Youth

NCT02472821
View directory record Official record
Conditions
Noise-induced Hearing Loss
Interventions
Interactive youth educational program, Internet-based educational booster
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
8 Years to 12 Years
Enrollment
2,093 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2016
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 27, 2017 · Synced Oct 21, 2026, 11:24 AM EDT
Recruiting Not applicable Interventional

Improving Clinical Efficiency by Reducing Scheduled Follow-ups Using Cochlear America's Population Mean Mapping Strategy

NCT06960616
View directory record Official record
Conditions
Deafness, Cochlear Hearing Loss
Interventions
Changes in traditional follow-up, Population mean mapping
Other
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years to 85 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated May 20, 2026 · Synced Oct 21, 2026, 11:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Hearing Aids and the Brain

NCT03279510
View directory record Official record
Conditions
Hearing Loss
Interventions
hearing aids
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Mar 24, 2023 · Synced Oct 21, 2026, 11:24 AM EDT
Terminated Phase 2 Interventional

Study of OTO-104 in Subjects at Risk From Cisplatin-Induced Hearing Loss

NCT02997189
View directory record Official record
Conditions
Cisplatin Induced Hearing Loss
Interventions
OTO-104
Drug
Lead sponsor
Otonomy, Inc.
Industry
Eligibility
6 Months to 21 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
San Diego, California
Source: ClinicalTrials.gov public record
Updated Sep 16, 2020 · Synced Oct 21, 2026, 11:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Hearing Aid Labeling on Speech Understanding Measures

NCT05274178
View directory record Official record
Conditions
Hearing Loss
Interventions
Audeo P hearing aid labeled as "Prescriptive", Audeo P hearing aid labeled as "OTC"
Device
Lead sponsor
Sonova AG
Industry
Eligibility
18 Years to 95 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Aurora, Illinois
Source: ClinicalTrials.gov public record
Updated Jul 10, 2023 · Synced Oct 21, 2026, 11:24 AM EDT
Recruiting Not applicable Interventional

Clinical Evaluation of Frequency Allocation for Bimodal CI Users

NCT06663917
View directory record Official record
Conditions
Hearing Impairment
Interventions
Experimental frequency allocation table (FAT) - 438 Hz, Standard FAT - 188 Hz
Other
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years and older
Enrollment
13 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 26, 2026 · Synced Oct 21, 2026, 11:24 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Music Appreciation After Cochlear Implantation

NCT04099368
View directory record Official record
Conditions
Hearing Loss, Cochlear Implants
Interventions
Musical pitch training
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
13 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Dec 26, 2025 · Synced Oct 21, 2026, 11:24 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Efficacy of the Bone-anchored Hearing Aid for Unilateral Deafness

NCT00201617
View directory record Official record
Conditions
Unilateral Deafness
Interventions
Bone-anchored hearing aid
Device
Lead sponsor
The New York Eye & Ear Infirmary
Other
Eligibility
18 Years to 70 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 14, 2015 · Synced Oct 21, 2026, 11:24 AM EDT
Withdrawn Not applicable Interventional Accepts healthy volunteers

Maintaining Cochlear Patency After VIIIth Nerve Surgery

NCT03261726
View directory record Official record
Conditions
Acoustic Neuroma, Labyrinthitis Ossificans, Profound Hearing Impairment
Interventions
MedEl Test Electrode Placer
Device
Lead sponsor
Henry Ford Health System
Other
Eligibility
Not listed
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Farmington Hills, Michigan
Source: ClinicalTrials.gov public record
Updated Dec 19, 2025 · Synced Oct 21, 2026, 11:24 AM EDT
Completed Not applicable Interventional Results available

A Simplified Patient-Centered Educational Tool for Improved Hearing-Aid Outcomes

NCT01940705
View directory record Official record
Conditions
Hearing Loss
Interventions
Hearing-Aid Informational Guide, Hearing-Aid DVD, Teach-back Technique, Standard of Care
Other · Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
50 Years to 89 Years
Enrollment
269 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Feb 21, 2019 · Synced Oct 21, 2026, 11:24 AM EDT
Completed Phase 1 Interventional Results available

Safety of Autologous Stem Cell Infusion for Children With Acquired Hearing Loss

NCT02038972
View directory record Official record
Conditions
Sensorineural Hearing Loss
Interventions
Autologous Stem Cells
Genetic
Lead sponsor
James Baumgartner, MD
Other
Eligibility
6 Weeks to 6 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
Orlando, Florida
Source: ClinicalTrials.gov public record
Updated Jul 9, 2026 · Synced Oct 21, 2026, 11:24 AM EDT
No Longer Available No phase listed Expanded access

Compassionate Use Arm - ABI541 ABI for 10 NF2 Patients

NCT02589912
View directory record Official record
Conditions
Neurofibromatosis Type 2, Severe Profound Sensorineural Hearing Loss
Interventions
Nucleus Profile ABI541 Auditory Brainstem Implant
Device
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
12 Years to 80 Years
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Dec 6, 2019 · Synced Oct 21, 2026, 11:24 AM EDT
Recruiting No phase listed Observational

Cross-sectional and Prospective Study to Characterize Early-onset Presbycusis

NCT06354010
View directory record Official record
Conditions
Sensorineural Hearing Loss, Bilateral
Interventions
Genotyping, Audiological assessments
Genetic · Other
Lead sponsor
Sensorion
Industry
Eligibility
30 Years to 55 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated May 8, 2026 · Synced Oct 21, 2026, 11:24 AM EDT
Completed Not applicable Interventional

Evaluating the Efficacy of Opti-Speech for Speech Treatment

NCT02705326
View directory record Official record
Conditions
Articulation Disorder, Dysarthria, Prelingual Deafness
Interventions
Opti-Speech
Device
Lead sponsor
Vulintus, Inc.
Industry
Eligibility
12 Years to 85 Years
Enrollment
37 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
2
States / cities
Cleveland, Ohio • Richardson, Texas
Source: ClinicalTrials.gov public record
Updated Dec 31, 2018 · Synced Oct 21, 2026, 11:24 AM EDT
Completed Not applicable Interventional Results available

Impact of Hearing Aid Service-delivery Model and Technology on Patient Outcomes

NCT03579563
View directory record Official record
Conditions
Presbycusis
Interventions
AUD fitting, OTC fitting, High-end HA, Low-end HA
Other · Device
Lead sponsor
Yu-Hsiang Wu
Other
Eligibility
55 Years to 85 Years
Enrollment
290 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2023
U.S. locations
2
States / cities
Iowa City, Iowa • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Oct 10, 2024 · Synced Oct 21, 2026, 11:24 AM EDT
Completed Phase 1 Interventional

Study to Evaluate Safety and Efficacy of DB-020 to Protect Hearing in Patients Receiving Cisplatin for Cancer Treatment

NCT04262336
View directory record Official record
Conditions
Ototoxicity
Interventions
DB-020, Placebo
Drug
Lead sponsor
Decibel Therapeutics
Industry
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
4
States / cities
Miami, Florida • Kansas City, Kansas • Lake Success, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Jul 6, 2023 · Synced Oct 21, 2026, 11:24 AM EDT
Recruiting No phase listed Observational

Otoferlin Gene-mediated Hearing Loss Natural History Study

NCT05572073
View directory record Official record
Conditions
Sensorineural Hearing Loss, Bilateral
Interventions
Natural History Study
Other
Lead sponsor
Akouos, Inc.
Industry
Eligibility
Up to 44 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
4
States / cities
Iowa City, Iowa • Cincinnati, Ohio • Philadelphia, Pennsylvania + 1 more
Source: ClinicalTrials.gov public record
Updated Mar 4, 2026 · Synced Oct 21, 2026, 11:24 AM EDT
Suspended Not applicable Interventional Accepts healthy volunteers

Improve the Patients' Recovery With Family- Caregivers to End Delirium

NCT05118867
View directory record Official record
Conditions
Delirium
Interventions
iPREPARED
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
60 Years and older
Enrollment
120 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2027
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 8, 2026 · Synced Oct 21, 2026, 11:24 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Study of the Effects of Anakinra in Corticosteroid-resistant Subjects With Sudden Sensorineural Hearing Loss

NCT02414152
View directory record Official record
Conditions
Hearing Loss, Sudden
Interventions
anakinra
Drug
Lead sponsor
Andrea Vambutas
Other
Eligibility
18 Years to 75 Years
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2015
U.S. locations
1
States / cities
New Hyde Park, New York
Source: ClinicalTrials.gov public record
Updated Mar 13, 2017 · Synced Oct 21, 2026, 11:24 AM EDT