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Showing 25–48 of 66 matching trials from the live ClinicalTrials.gov search.
Conditions
Sensorineural Hearing Loss, Bilateral Hearing Loss
Interventions
CI632D, CI632
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
3
States / cities
Englewood, Colorado • Iowa City, Iowa • Cleveland, Ohio
Recruiting Not applicable Interventional

Sentence Shaping - DHH

NCT06860022
Conditions
Hearing Loss, Bilateral
Interventions
Shape Coding
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
9 Years to 15 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Nashville, Tennessee
Terminated Not applicable Interventional Results available

The Effect of Low-Level Laser Stimulation on Hearing Thresholds

NCT01820416
Conditions
Hearing Loss
Interventions
Low-level Laser Therapy, Placebo Comparator: Disabled Laser
Radiation · Other
Lead sponsor
University of Iowa
Other
Eligibility
18 Years to 75 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Bilateral Hearing Loss for Causes Other Than Tumors
Interventions
Nucleus 24 (discontinued) and ABI541 Auditory Brainstem Implants (ABI)
Device
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years and older
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2019
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Results available

Hearing Aid and Individuals With Cognitive Disorders

NCT04049643
Conditions
Presbycusis, Bilateral, Alzheimer Disease 2 Due to Apoe4 Isoform, Mild Cognitive Impairment
Interventions
Audiologist-based fitting, Service-only Fitting, Device-only fitting
Device
Lead sponsor
Yu-Hsiang Wu
Other
Eligibility
55 Years to 85 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
2
States / cities
Iowa City, Iowa • Nashville, Tennessee
Conditions
Hearing Loss
Interventions
Hearing amplification
Device
Lead sponsor
Duke University
Other
Eligibility
50 Years and older
Enrollment
278 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2024
U.S. locations
2
States / cities
Durham, North Carolina • Nashville, Tennessee
Completed Not applicable Interventional Accepts healthy volunteers Results available

Iowa/Nucleus 10/10 mm and Nucleus Freedom Feasibility Study

NCT00594061
Conditions
Hearing Loss, Sensorineural, Hearing Loss, Bilateral
Interventions
Iowa/Nucleus 10/10 mm and Freedom Cochlear Implantation
Device
Lead sponsor
Bruce J Gantz
Other
Eligibility
12 Months to 24 Months
Enrollment
9 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2016
U.S. locations
1
States / cities
Iowa City, Iowa
Enrolling by invitation No phase listed Observational

Long Term Follow-up Study of AAVAnc80-hOTOF Gene Therapy

NCT06696456
Conditions
Otoferlin Gene-mediated Hearing Loss
Interventions
Not listed
Lead sponsor
Akouos, Inc.
Industry
Eligibility
Not listed
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2033
U.S. locations
3
States / cities
Iowa City, Iowa • Boston, Massachusetts • Philadelphia, Pennsylvania
Conditions
Unilateral Severe to Profound Hearing Loss OR Bilateral Severe to Profound Hearing Loss
Interventions
CGF166
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
4
States / cities
Kansas City, Kansas • Baltimore, Maryland • New York, New York + 1 more
Conditions
Bilateral Sensorineural Hearing Loss
Interventions
Cochlear implant
Device
Lead sponsor
American Cochlear Implant Alliance
Other
Eligibility
65 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
19
States / cities
Los Angeles, California • Englewood, Colorado • Miami, Florida + 16 more
Conditions
Hearing Loss, Sensorineural, Sensorineural Hearing Loss, Bilateral, Cochlear Implant Recipients, Asymmetric Hearing Loss
Interventions
Bimodal Streaming Configuration
Device
Lead sponsor
Med-El Corporation
Industry
Eligibility
Not listed
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Meridian, Idaho
Conditions
Bilateral Hearing Loss, Health Services Research
Interventions
Pharmacy Technician Educational Training
Behavioral
Lead sponsor
University of Alabama, Tuscaloosa
Other
Eligibility
18 Years and older
Enrollment
144 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2027
U.S. locations
2
States / cities
Tuscaloosa, Alabama
Conditions
Hearing Loss, Sensorineural, Hearing Loss, Hearing Loss, Bilateral
Interventions
Electrocochleography
Device
Lead sponsor
Ohio State University
Other
Eligibility
18 Years to 79 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2027
U.S. locations
5
States / cities
Rochester, Minnesota • St Louis, Missouri • Chapel Hill, North Carolina + 2 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Direct-to-Consumer Hearing Aids and Listening Effort

NCT05855005
Conditions
Hearing Loss, Hearing Loss, Sensorineural, Hearing Loss, Bilateral
Interventions
DTC Hearing Aids
Device
Lead sponsor
Northwestern University
Other
Eligibility
18 Years to 90 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
2
States / cities
Chicago, Illinois • Evanston, Illinois
Conditions
Profound Bilateral Deafness Due to, Bilateral Cochlear Aplasia, Bilateral Cochlear Nerve Deficiency, Bilateral Cochlear Ossification Secondary to Meningitis
Interventions
Auditory Brainstem Implant
Device
Lead sponsor
Laurie Eisenberg
Other
Eligibility
2 Years to 6 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
2
States / cities
Los Angeles, California
Not yet recruiting Not applicable Interventional

Noise Reduction With Hearing Aids

NCT07700043
Conditions
Bilateral Sensorineural Hearing Loss
Interventions
Speech Enhancement using Decomposition Approach-Hearing Aid (SEDA-HA) algorithm, Hearing aid (HA) prototype with SEDA-HA algorithm
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
16 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2029
U.S. locations
1
States / cities
New York, New York
Conditions
Hearing Loss, Bilateral
Interventions
hearing instruments
Device
Lead sponsor
Sonova AG
Industry
Eligibility
18 Years to 95 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Tampa, Florida
Conditions
Deafness, Bilateral
Interventions
Parent-Child Early Approaches to Raising Language Skills, Standard Care Speech therapy
Behavioral · Other
Lead sponsor
University of Miami
Other
Eligibility
12 Months to 48 Months
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2021
U.S. locations
1
States / cities
Miami, Florida
Conditions
Sensorineural Hearing Loss, Bilateral
Interventions
Natural History Study
Other
Lead sponsor
Akouos, Inc.
Industry
Eligibility
Up to 44 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
4
States / cities
Iowa City, Iowa • Cincinnati, Ohio • Philadelphia, Pennsylvania + 1 more
Conditions
Hearing Loss, Bilateral or Unilateral
Interventions
Phonak Audeo Infinio Hearing Aid
Device
Lead sponsor
Sonova AG
Industry
Eligibility
18 Years to 95 Years
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025
U.S. locations
1
States / cities
Aurora, Illinois
Conditions
Hearing Loss
Interventions
HiRes 90K Bionic Ear System
Device
Lead sponsor
Advanced Bionics
Industry
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2009
U.S. locations
9
States / cities
Los Angeles, California • Palo Alto, California • Miami, Florida + 6 more
Completed No phase listed Observational Accepts healthy volunteers

Neural Changes in the Aging Auditory System

NCT00264407
Conditions
Progesterone, Estrogens, Hearing, Psychoacoustics, Auditory Perceptual Disorders
Interventions
Hormone Replacement Therapy - HRT
Drug
Lead sponsor
University of Rochester
Other
Eligibility
60 Years to 86 Years · Female only
Enrollment
126 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2005
U.S. locations
2
States / cities
Rochester, New York
Conditions
GJB2-mediated Hearing Loss, GJB2 Gene Mutation, DFNB1A
Interventions
SKY-GJB2
Combination Product
Lead sponsor
Skylark Bio Inc.
Industry
Eligibility
9 Months to 7 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
4
States / cities
Bethesda, Maryland • Boston, Massachusetts • Oklahoma City, Oklahoma + 1 more
Conditions
Hearing Aids, Hearing Loss, Bilateral Sensorineural, 3D Printing
Interventions
BTE hearing aids with compatible ear tips (Third-party, FlexResin, Resin), BTE hearing aids with compatible ear tips (FlexResin, Resin, Third-party, FlexResin), BTE hearing aids with compatible ear tips (Resin, Third-party, FlexRes)
Device
Lead sponsor
University of Arizona
Other
Eligibility
18 Years to 89 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Tucson, Arizona