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Showing 1–24 of 44 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Deafness, Unilateral Clear all
Completed Not applicable Interventional Results available

Bone Conduction Auditory Performance Via the Tooth for Single-Sided Deafness

NCT00977314
View directory record Official record
Conditions
Unilateral Hearing Loss
Interventions
The Sonitus Bone Conduction Hearing System, SoundBite, SoundBite Hearing System
Device
Lead sponsor
Sonitus Medical Inc
Industry
Eligibility
18 Years to 80 Years
Enrollment
35 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2010
U.S. locations
2
States / cities
Redwood City, California • San Jose, California
Source: ClinicalTrials.gov public record
Updated Oct 16, 2014 · Synced Jul 21, 2026, 8:05 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Determine the Incidence of Long QT Amongst a Large Cohort of Subjects Diagnosed With Unilateral or Bilateral Sensorineural Hearing Loss.

NCT02082431
View directory record Official record
Conditions
Sensorineural Hearing Loss, Long QT Syndrome
Interventions
Not listed
Lead sponsor
Pediatrix
Other
Eligibility
1 Day to 90 Days
Enrollment
600 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2020
U.S. locations
12
States / cities
Anchorage, Alaska • Phoenix, Arizona • Waterford, Connecticut + 6 more
Source: ClinicalTrials.gov public record
Updated Oct 4, 2020 · Synced Jul 21, 2026, 8:05 PM EDT
Enrolling by invitation Not applicable Interventional

Impact of Anatomy-Based Cochlear Implant Programming on Early Performance

NCT06734039
View directory record Official record
Conditions
Hearing Loss, Unilateral, Cochlear Implants, Hearing Loss, Sensorineural, Single-Sided Deafness (SSD), Asymmetric Hearing Loss
Interventions
Programming of cochlear implant audio processor frequency settings
Device
Lead sponsor
Med-El Corporation
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
6
States / cities
Iowa City, Iowa • Kansas City, Kansas • Chapel Hill, North Carolina + 3 more
Source: ClinicalTrials.gov public record
Updated Mar 26, 2026 · Synced Jul 21, 2026, 8:05 PM EDT
Recruiting Phase 1Phase 2 Interventional

Anti-VEGF Gene Therapy Trial for Vestibular Schwannoma

NCT06517888
View directory record Official record
Conditions
Vestibular Schwannoma
Interventions
AAVAnc80-antiVEGF via Akouos Delivery Device
Combination Product
Lead sponsor
Akouos, Inc.
Industry
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2029
U.S. locations
4
States / cities
Baltimore, Maryland • Rochester, Minnesota • Nashville, Tennessee + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 5, 2026 · Synced Jul 21, 2026, 8:05 PM EDT
Terminated Phase 3 Interventional Results available

Efficacy and Safety of AM-111 as Acute Sudden Sensorineural Hearing Loss Treatment

NCT02809118
View directory record Official record
Conditions
Hearing Loss, Idiopathic Sudden Sensorineural
Interventions
AM-111 0.4 mg/ml, AM-111 0.8 mg/ml, Placebo
Drug · Other
Lead sponsor
Auris Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
38
States / cities
Birmingham, Alabama • Escondido, California • Fresno, California + 34 more
Source: ClinicalTrials.gov public record
Updated Aug 6, 2020 · Synced Jul 21, 2026, 8:05 PM EDT
Recruiting Not applicable Interventional

Investigation to Evaluate the Safety and Effectiveness of Cochlear Implantation in Children and Adults With Unilateral Hearing Loss/Single-sided Deafness

NCT05318417
View directory record Official record
Conditions
Hearing Loss, Unilateral, Deafness, Unilateral
Interventions
The Cochlear™ Nucleus® Cochlear Implant (CI) System
Device
Lead sponsor
Cochlear
Industry
Eligibility
5 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
8
States / cities
Palo Alto, California • Englewood, Colorado • Iowa City, Iowa + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2025 · Synced Jul 21, 2026, 8:05 PM EDT
Completed Phase 1 Interventional

OTO-104 for Meniere's Disease

NCT01084525
View directory record Official record
Conditions
Meniere's Disease
Interventions
OTO-104 (steroid) 3 mg, Placebo, OTO-104 (steroid) 12 mg
Drug
Lead sponsor
Otonomy, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2011
U.S. locations
15
States / cities
Los Angeles, California • San Diego, California • Colorado Springs, Colorado + 12 more
Source: ClinicalTrials.gov public record
Updated Jun 7, 2011 · Synced Jul 21, 2026, 8:05 PM EDT
Completed No phase listed Observational

Use of RM Technology in Pediatric BAI Recipients

NCT03149484
View directory record Official record
Conditions
Hearing Loss, Unilateral
Interventions
Personal remote microphone (RM) system, Subjective Questionnaire
Device · Other
Lead sponsor
University of Miami
Other
Eligibility
5 Years to 18 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Apr 26, 2023 · Synced Jul 21, 2026, 8:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Wide Diameter Bone Anchored Implant Study

NCT01671176
View directory record Official record
Conditions
Conductive Hearing Loss, Conductive and Sensori-neural Hearing Loss in the Same Ear, Unilateral, Profound Sensori-neural Hearing Loss
Interventions
Wide diameter bone anchored implant
Device
Lead sponsor
Oticon Medical
Industry
Eligibility
18 Years and older
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
2
States / cities
Sarasota, Florida • Farmington Hills, Michigan
Source: ClinicalTrials.gov public record
Updated May 6, 2018 · Synced Jul 21, 2026, 8:05 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Efficacy of the Bone-anchored Hearing Aid for Unilateral Deafness

NCT00201617
View directory record Official record
Conditions
Unilateral Deafness
Interventions
Bone-anchored hearing aid
Device
Lead sponsor
The New York Eye & Ear Infirmary
Other
Eligibility
18 Years to 70 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2007
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Apr 13, 2015 · Synced Jul 21, 2026, 8:05 PM EDT
Completed Not applicable Interventional Results available

Cochlear Implantation in Cases of Single-Sided Deafness

NCT02203305
View directory record Official record
Conditions
Unilateral Moderate to Profound Hearing Loss, Asymmetric Hearing Loss, Single-Sided Deafness (SSD)
Interventions
Cochlear Implant, Control Group
Device · Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
43 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Jul 24, 2022 · Synced Jul 21, 2026, 8:05 PM EDT
Completed No phase listed Observational

Iowa Cochlear Implant Clinical Research Center Study of SSD Using Med-El Cochlear Implants

NCT03929809
View directory record Official record
Conditions
Hearing Loss, Unilateral, Hearing Loss, Profound
Interventions
Cochlear Implant
Device
Lead sponsor
University of Iowa
Other
Eligibility
18 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Sep 28, 2021 · Synced Jul 21, 2026, 8:05 PM EDT
Not listed No phase listed Observational

SoundBite Hearing System Long Term Multi Site Patient Use Study

NCT01445977
View directory record Official record
Conditions
Single Sided Deafness, Conductive Hearing Loss
Interventions
Not listed
Lead sponsor
Sonitus Medical Inc
Industry
Eligibility
18 Years and older
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
13
States / cities
Phoenix, Arizona • La Jolla, California • Newport Beach, California + 10 more
Source: ClinicalTrials.gov public record
Updated Aug 1, 2013 · Synced Jul 21, 2026, 8:05 PM EDT
Not listed No phase listed Observational

SoundBite Hearing System 24 Month Multi Site Patient Use Study

NCT01807559
View directory record Official record
Conditions
Single Sided Deafness, Conductive Hearing Loss
Interventions
SoundBite Hearing System
Device
Lead sponsor
Sonitus Medical Inc
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
7
States / cities
Phoenix, Arizona • La Jolla, California • Newport Beach, California + 4 more
Source: ClinicalTrials.gov public record
Updated May 2, 2013 · Synced Jul 21, 2026, 8:05 PM EDT
Terminated Not applicable Interventional Results available

Adhear Bone Conduction System

NCT03533686
View directory record Official record
Conditions
Hearing Loss, Conductive, Hearing Loss, Unilateral
Interventions
Adhear Bone Conduction System, Bone anchored hearing aid (BAHA)
Device
Lead sponsor
University of Miami
Other
Eligibility
2 Years and older
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2022
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Aug 7, 2023 · Synced Jul 21, 2026, 8:05 PM EDT
Completed No phase listed Observational

Cochlear Implantation Among Adults and Older Children With Unilateral or Asymmetric Hearing Loss

NCT02105441
View directory record Official record
Conditions
Severe Unilateral Sensorineural Hearing Loss
Interventions
Cochlear implant
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
7 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 4, 2018 · Synced Jul 21, 2026, 8:05 PM EDT
Completed Phase 1Phase 2 Interventional Accepts healthy volunteers Results available

Phase I/IIa Study Evaluating Safety and Efficacy of an Intratympanic Dose of PIPE-505 in Subjects With Hearing Loss

NCT04462198
View directory record Official record
Conditions
Sensorineural Hearing Loss
Interventions
PIPE-505, Placebo
Drug
Lead sponsor
Contineum Therapeutics
Industry
Eligibility
18 Years to 75 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
8
States / cities
Torrance, California • Boca Raton, Florida • New Albany, Indiana + 5 more
Source: ClinicalTrials.gov public record
Updated Mar 31, 2025 · Synced Jul 21, 2026, 8:05 PM EDT
Completed Not applicable Interventional Results available

Long Term Safety of the Sonitus SoundBite System

NCT01108406
View directory record Official record
Conditions
Hearing Loss, Unilateral Hearing Loss, Total Unilateral Deafness
Interventions
Sonitus SoundBite System, SoundBite Hearing System
Device
Lead sponsor
Sonitus Medical Inc
Industry
Eligibility
18 Years to 80 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010
U.S. locations
1
States / cities
San Jose, California
Source: ClinicalTrials.gov public record
Updated Oct 19, 2014 · Synced Jul 21, 2026, 8:05 PM EDT
Completed Early Phase 1 Interventional

Balance in Children With Cochlear Implants

NCT00642343
View directory record Official record
Conditions
Severe, Profound Deafness
Interventions
Evaluation of motor proficiency skills., Evaluation of motor proficiency.
Behavioral
Lead sponsor
University of Oklahoma
Other
Eligibility
4 Years to 18 Years
Enrollment
66 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2010
U.S. locations
1
States / cities
Oklahoma City, Oklahoma
Source: ClinicalTrials.gov public record
Updated Jun 14, 2010 · Synced Jul 21, 2026, 8:05 PM EDT
Recruiting Phase 1Phase 2 Interventional

Open-label Study of SKY-GJB2 in Pediatric Subjects With GJB2-mediated Hearing Loss

NCT07627971
View directory record Official record
Conditions
GJB2-mediated Hearing Loss, GJB2 Gene Mutation, DFNB1A
Interventions
SKY-GJB2
Combination Product
Lead sponsor
Skylark Bio Inc.
Industry
Eligibility
9 Months to 7 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
3
States / cities
Boston, Massachusetts • Oklahoma City, Oklahoma • Allentown, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Jul 21, 2026, 8:05 PM EDT
Completed Not applicable Interventional Results available

Evaluation of the Baha SoundArc in Pediatric Patients

NCT03333577
View directory record Official record
Conditions
Hearing Loss, Conductive, Hearing Loss, Mixed, Hearing Loss, Unilateral
Interventions
SoundArc
Device
Lead sponsor
Cochlear
Industry
Eligibility
5 Years to 12 Years
Enrollment
32 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
3
States / cities
Chandler, Arizona • San Diego, California • Fort Worth, Texas
Source: ClinicalTrials.gov public record
Updated Apr 29, 2019 · Synced Jul 21, 2026, 8:05 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Cochlear Implantation in Pediatric Cases of Unilateral Hearing Loss

NCT02963974
View directory record Official record
Conditions
Hearing Loss, Unilateral
Interventions
Cochlear implant
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
42 Months to 78 Months
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Aug 5, 2021 · Synced Jul 21, 2026, 8:05 PM EDT
Recruiting Phase 1Phase 2 Interventional

A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations

NCT05788536
View directory record Official record
Conditions
Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)
Interventions
DB-OTO
Genetic
Lead sponsor
Regeneron Pharmaceuticals
Industry
Eligibility
Not listed
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2032
U.S. locations
9
States / cities
Los Angeles, California • San Diego, California • Jacksonville, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Jul 21, 2026, 8:05 PM EDT
Completed Phase 3 Interventional Results available

Sudden Deafness Treatment Trial

NCT00097448
View directory record Official record
Conditions
Sudden Deafness
Interventions
prednisone, methylprednisolone sodium succinate
Drug
Lead sponsor
Massachusetts Eye and Ear Infirmary
Other
Eligibility
18 Years and older
Enrollment
255 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2011
U.S. locations
14
States / cities
Los Angeles, California • San Diego, California • Gainesville, Florida + 10 more
Source: ClinicalTrials.gov public record
Updated Apr 3, 2017 · Synced Jul 21, 2026, 8:05 PM EDT