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Showing 1–15 of 15 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Deafness With a Cochlear Implant Clear all
Completed Phase 1Phase 2 Interventional Results available

Safety, Tolerability and Efficacy for CGF166 in Patients With Unilateral or Bilateral Severe-to-profound Hearing Loss

NCT02132130
View directory record Official record
Conditions
Unilateral Severe to Profound Hearing Loss OR Bilateral Severe to Profound Hearing Loss
Interventions
CGF166
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
4
States / cities
Kansas City, Kansas • Baltimore, Maryland • New York, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Oct 7, 2021 · Synced Jul 22, 2026, 9:58 PM EDT
Completed Not applicable Interventional Results available

Evaluation of Speech-in-noise Performance in Cochlear Implant Recipients With a CROS Device on the Contralateral Ear

NCT03867396
View directory record Official record
Conditions
Hearing Loss, Sensorineural
Interventions
CROS, Hearing Aid, Cochlear Implant Alone
Device · Other
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 89 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 15, 2022 · Synced Jul 22, 2026, 9:58 PM EDT
Recruiting Not applicable Interventional

Evaluation of the Automated Integration of a Robotics and ECochG System for Use With Cochlear Implant Surgery

NCT06664710
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Cochlear Implantation
Interventions
iotaSOFT Insertion System with AIM, iotaSOFT Insertion System with AIM Control
Device
Lead sponsor
iotaMotion, Inc.
Industry
Eligibility
12 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Apr 30, 2025 · Synced Jul 22, 2026, 9:58 PM EDT
Recruiting Phase 1Phase 2 Interventional

A Study of DB-OTO, an Adeno-Associated Virus (AAV) Based Gene Therapy, in Children/Infants, Adolescents and Adults With Hearing Loss Due to Otoferlin Mutations

NCT05788536
View directory record Official record
Conditions
Congenital Hearing Loss Secondary to Biallelic Mutations of the Otoferlin Gene (OTOF)
Interventions
DB-OTO
Genetic
Lead sponsor
Regeneron Pharmaceuticals
Industry
Eligibility
Not listed
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2032
U.S. locations
9
States / cities
Los Angeles, California • San Diego, California • Jacksonville, Florida + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 30, 2026 · Synced Jul 22, 2026, 9:58 PM EDT
Active, not recruiting Not applicable Interventional

Stimulating the Cochlear Apex Without Longer Electrodes

NCT06901674
View directory record Official record
Conditions
Deafness With a Cochlear Implant
Interventions
Modified surgical approach, Cochlear Nucleus CI632 cochlear implant
Procedure · Device
Lead sponsor
NYU Langone Health
Other
Eligibility
18 Years to 90 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 5, 2026 · Synced Jul 22, 2026, 9:58 PM EDT
Not yet recruiting Not applicable Interventional

Hearing Outcomes With the Nucleus® 8 Sound Processor and Nucleus® 7 Sound Processor in Adult Veteran and Non-veteran Cochlear Implant Recipients

NCT07582198
View directory record Official record
Conditions
Hearing Loss
Interventions
Nucleus 7 Sound Processor, Nucleus 8 Sound Processor
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026
U.S. locations
1
States / cities
Lone Tree, Colorado
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Jul 22, 2026, 9:58 PM EDT
Completed Not applicable Interventional Results available

Comparing the Performance of a Categorical Loudness Scaling Based Fitting With a Behavioural Fitting in Adults With a Nucleus Cochlear Implant 3 Months Post-activation

NCT05709223
View directory record Official record
Conditions
Hearing Loss
Interventions
Categorical loudness scaling based fitting using the research fitting system., Behavioural fitting using Custom Sound Suite (CSS 6.3) Software
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Lone Tree, Colorado
Source: ClinicalTrials.gov public record
Updated May 14, 2026 · Synced Jul 22, 2026, 9:58 PM EDT
Recruiting Not applicable Interventional

Investigation to Evaluate the Safety and Effectiveness of Cochlear Implantation in Children and Adults With Unilateral Hearing Loss/Single-sided Deafness

NCT05318417
View directory record Official record
Conditions
Hearing Loss, Unilateral, Deafness, Unilateral
Interventions
The Cochlear™ Nucleus® Cochlear Implant (CI) System
Device
Lead sponsor
Cochlear
Industry
Eligibility
5 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
8
States / cities
Palo Alto, California • Englewood, Colorado • Iowa City, Iowa + 5 more
Source: ClinicalTrials.gov public record
Updated Sep 1, 2025 · Synced Jul 22, 2026, 9:58 PM EDT
Recruiting Not applicable Interventional

Evaluating a Noise Reduction Algorithm With Cochlear Implant Users

NCT05805384
View directory record Official record
Conditions
Hearing Impairment
Interventions
SEDA
Device
Lead sponsor
NYU Langone Health
Other
Eligibility
12 Years and older
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 16, 2025 · Synced Jul 22, 2026, 9:58 PM EDT
Recruiting Not applicable Interventional

A Pivotal Study to Evaluate the Clinical Benefit, Performance and Safety of a Totally Implantable Cochlear Implant (TICI) System in Adults

NCT07287124
View directory record Official record
Conditions
Hearing Loss, Bilateral Sensorineural
Interventions
Cochlear implant
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
56 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
11
States / cities
Englewood, Colorado • Miami, Florida • Iowa City, Iowa + 8 more
Source: ClinicalTrials.gov public record
Updated Jun 22, 2026 · Synced Jul 22, 2026, 9:58 PM EDT
Completed Not applicable Interventional Results available

Clinical Evaluation of a Cochlear Implant Sound Processor

NCT04237207
View directory record Official record
Conditions
Hearing Loss, Ear Diseases, Hearing Disorders, Otorhinolaryngologic Diseases
Interventions
Naída Cochlear Implant Q90 sound processor (Naida CI Q90) & software, 301-M062 sound processor & software
Device
Lead sponsor
Advanced Bionics
Industry
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
6
States / cities
Aurora, Colorado • Tampa, Florida • Kansas City, Missouri + 3 more
Source: ClinicalTrials.gov public record
Updated May 12, 2022 · Synced Jul 22, 2026, 9:58 PM EDT
Withdrawn No phase listed Observational

A Natural History Study in Pediatric Participants With Hearing Loss Due to OTOF, GJB2, or GJB2/GJB6 Mutations

NCT06019481
View directory record Official record
Conditions
Congenital Hearing Loss Secondary to Biallelic Mutations in the Otoferlin Gene (OTOF), Biallelic Mutations in the Gap Junction Beta 2 (GJB2) Gene, Digenic Mutations in GJB2/Gap Junction Beta 6 (GJB6) Genes
Interventions
Not listed
Lead sponsor
Regeneron Pharmaceuticals
Industry
Eligibility
Up to 7 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2030
U.S. locations
2
States / cities
Phoenix, Arizona • Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated May 14, 2025 · Synced Jul 22, 2026, 9:58 PM EDT
Recruiting No phase listed Observational

Long-term Follow-up of a Cochlear Implant With Dexamethasone Eluting Electrode Array

NCT06936449
View directory record Official record
Conditions
Sensorineural Hearing Loss, Bilateral Hearing Loss
Interventions
CI632D, CI632
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
3
States / cities
Englewood, Colorado • Iowa City, Iowa • Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Jul 22, 2026, 9:58 PM EDT
Terminated Not applicable Interventional Results available

Implantation of the HiRes90K™ Advantage Cochlear Implant With HiFocus™ Mid-Scala and Development of a Combined Electric and Acoustic Stimulation Technology in Adults With Partial Deafness

NCT02189798
View directory record Official record
Conditions
Hearing Loss, Partial Deafness, Hearing Disorders, Ear Diseases, Otorhinolaryngologic Diseases
Interventions
HiRes 90K™ Advantage implant with HiFocus™ Mid-Scala electrode, EAS sound processor
Device
Lead sponsor
Advanced Bionics
Industry
Eligibility
18 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2022
U.S. locations
11
States / cities
Washington D.C., District of Columbia • Tampa, Florida • Lexington, Kentucky + 7 more
Source: ClinicalTrials.gov public record
Updated May 7, 2025 · Synced Jul 22, 2026, 9:58 PM EDT
Active, not recruiting Not applicable Interventional

Safety and Effectiveness of Cochlear Implantation in an Expanded Adult Population

NCT06293482
View directory record Official record
Conditions
Hearing Loss, Sensorineural, Hearing Loss, Bilateral
Interventions
Cochlear™ Nucleus® System
Device
Lead sponsor
Cochlear
Industry
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2028
U.S. locations
9
States / cities
Phoenix, Arizona • Tucson, Arizona • Santa Monica, California + 6 more
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jul 22, 2026, 9:58 PM EDT