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Showing 1–24 of 309 matching trials from the live ClinicalTrials.gov search.
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Withdrawn No phase listed Observational

Muscle Atrophy in Sepsis

NCT00583206
View directory record Official record
Conditions
Atrophy, Sepsis, Weakness
Interventions
Not listed
Lead sponsor
Gregory A. Schmidt
Other
Eligibility
18 Years to 99 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2009
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 27, 2017 · Synced Jul 20, 2026, 6:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Combination Treatment With BTL-899 and HPM-6000UF Devices II

NCT05713864
View directory record Official record
Conditions
Muscle Weakness
Interventions
BTL-899, HPM-6000UF
Device
Lead sponsor
BTL Industries Ltd.
Industry
Eligibility
22 Years and older · Female only
Enrollment
33 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
3
States / cities
Gilbert, Arizona • River Bluff, Kentucky • West Columbia, South Carolina
Source: ClinicalTrials.gov public record
Updated Apr 12, 2023 · Synced Jul 20, 2026, 6:39 PM EDT
Active, not recruiting Not applicable Interventional Accepts healthy volunteers

NuroSleeve Powered Brace & Stimulation System to Restore Arm Function

NCT04798378
View directory record Official record
Conditions
Neurologic Diseases, Hemiparesis, Quadriplegia, Muscular Dystrophies, Arthrogryposis, Spinal Cord Injuries, Charcot-Marie-Tooth, Stroke, Weakness of Extremities as Sequela of Stroke, Weakness Due to Upper Motor Neuron Dysfunction, Amyotrophic Lateral Sclerosis, Spinal Muscular Atrophy, Arm Paralysis, Cerebral Palsy
Interventions
Neurosleeve
Device
Lead sponsor
Thomas Jefferson University
Other
Eligibility
4 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2026
U.S. locations
2
States / cities
Wilmington, Delaware • Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 8, 2025 · Synced Jul 20, 2026, 6:39 PM EDT
Completed Phase 4 Interventional Results available

A Prospective Analysis of Preoperative Fascia Iliaca Block for Hip Arthroscopy

NCT02623361
View directory record Official record
Conditions
Muscle Weakness | Patient, Pain
Interventions
Peripheral Nerve Block, Sham Block
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years to 99 Years
Enrollment
80 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Dec 26, 2018 · Synced Jul 20, 2026, 6:39 PM EDT
Completed Not applicable Interventional

A Pilot Study of Rehabilitation Among Intensive Care Unit (ICU) Survivors: the RETURN Trial

NCT00715494
View directory record Official record
Conditions
Brain Injury, Muscle Weakness
Interventions
Cognitive, physical, and functional rehabilitation
Behavioral
Lead sponsor
Vanderbilt University
Other
Eligibility
18 Years to 100 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2015
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 10, 2018 · Synced Jul 20, 2026, 6:39 PM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Use of Repetitive Facilitative Exercise Program in Established Stroke

NCT01574599
View directory record Official record
Conditions
Stroke
Interventions
Occupational therapy- Repetitive Facilitative Exercise
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2016
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 21, 2017 · Synced Jul 20, 2026, 6:39 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Evaluation of Thermal-Aided Muscle Stimulation

NCT01911312
View directory record Official record
Conditions
Weakness, Atrophy
Interventions
Thermal-aided muscle stimulation, Body Temperature Stimulation
Device
Lead sponsor
Niveus Medical, Inc.
Industry
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
Started 2013
U.S. locations
1
States / cities
Mountain View, California
Source: ClinicalTrials.gov public record
Updated Jul 29, 2013 · Synced Jul 20, 2026, 6:39 PM EDT
Completed Phase 4 Interventional Results available

Sugammadex Versus Neostigmine for Reversal of Neuromuscular Blockade at the End of Kidney Transplantation Surgery

NCT03923556
View directory record Official record
Conditions
Kidney Transplant; Complications, Postoperative Residual Curarization, Postoperative Residual Weakness
Interventions
Sugammadex, Neostigmine
Drug
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years to 90 Years
Enrollment
84 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2023
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated May 21, 2025 · Synced Jul 20, 2026, 6:39 PM EDT
Active, not recruiting No phase listed Observational

Measuring Outcomes of Activity in Intensive Care

NCT03115840
View directory record Official record
Conditions
Critical Illness, Sepsis, Mechanical Ventilation, Physical Activity, Disability Physical, Muscle Weakness, Cognitive Impairment
Interventions
Not listed
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
312 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2030
U.S. locations
2
States / cities
Columbus, Ohio • Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 2, 2026 · Synced Jul 20, 2026, 6:39 PM EDT
Completed Phase 1 Interventional Results available

Electrical Stimulation for Critically Ill Covid-19 Patients

NCT04685213
View directory record Official record
Conditions
Covid19, Muscle Atrophy, Muscle Weakness
Interventions
Electrical Stimulation, Electrical Stimulation - Sham
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 100 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 15, 2023 · Synced Jul 20, 2026, 6:39 PM EDT
Enrolling by invitation No phase listed Observational Accepts healthy volunteers

Digital Care Programs for Female Pelvic Health

NCT05513417
View directory record Official record
Conditions
Pelvic Floor Disorders, Pelvic Pain, Pelvic Organ Prolapse, Pelvic Floor Muscle Weakness, Pelvic Pain Syndrome
Interventions
Bloom Pod
Device
Lead sponsor
Sword Health, SA
Industry
Eligibility
18 Years to 99 Years · Female only
Enrollment
50,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2032
U.S. locations
1
States / cities
Draper, Utah
Source: ClinicalTrials.gov public record
Updated Dec 5, 2024 · Synced Jul 20, 2026, 6:39 PM EDT
Not listed No phase listed Observational Accepts healthy volunteers

Influence of Directional Preference on Movement Coordination Deficits in Individuals With Whiplash Associated Disorders

NCT06143228
View directory record Official record
Conditions
Whiplash Injury of Cervical Spine, Muscle Weakness
Interventions
Not listed
Lead sponsor
D'Youville College
Other
Eligibility
19 Years to 70 Years
Enrollment
65 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
2
States / cities
Tallahassee, Florida • Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Feb 21, 2024 · Synced Jul 20, 2026, 6:39 PM EDT
Terminated Phase 2 Interventional Results available

Efficacy and Tolerability of BAF312 in Patients With Polymyositis and Dermatomyositis

NCT01148810
View directory record Official record
Conditions
Polymyositis, Dermatomyositis
Interventions
BAF312, Placebo
Drug
Lead sponsor
Novartis Pharmaceuticals
Industry
Eligibility
18 Years to 75 Years
Enrollment
18 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2019 · Synced Jul 20, 2026, 6:39 PM EDT
Completed Not applicable Interventional

Healthy Weight and Stress Management Study

NCT05279989
View directory record Official record
Conditions
Physical Disability, Obesity, Muscle Weakness, Anxiety, Depression
Interventions
Seated Tai Chi Qigong, Health Information Videos
Other
Lead sponsor
Arizona State University
Other
Eligibility
35 Years to 64 Years · Female only
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Feb 1, 2023 · Synced Jul 20, 2026, 6:39 PM EDT
Completed Phase 2 Interventional Results available

Electrical Stimulation for Critically Ill Post-Covid-19 Patients

NCT05198466
View directory record Official record
Conditions
COVID-19, Muscle Atrophy, Muscle Weakness
Interventions
Electrical Stimulation, Electrical Stimulation - Sham
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 100 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Mar 6, 2023 · Synced Jul 20, 2026, 6:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

The UNCODE Study: Unravelling the Neural Contributors Of Dynapenia in Elders

NCT02505529
View directory record Official record
Conditions
Aging
Interventions
Resistance Exercise Training, Mental Imagery
Other
Lead sponsor
Ohio University
Other
Eligibility
60 Years and older
Enrollment
89 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2018
U.S. locations
1
States / cities
Athens, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 12, 2019 · Synced Jul 20, 2026, 6:39 PM EDT
Active, not recruiting Not applicable Interventional

A Study of Healthy Microbiome, Healthy Mind

NCT06020703
View directory record Official record
Conditions
Critical Illness, COVID-19, PICS, Cognitive Impairment, Mental Health Impairment, Weakness, Muscle, Dysbiosis
Interventions
Fermented Food Diet
Behavioral
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 2, 2026 · Synced Jul 20, 2026, 6:39 PM EDT
Completed No phase listed Observational

Osteoarthritis: Weakness From Inflammation

NCT00104312
View directory record Official record
Conditions
Osteoarthritis
Interventions
Not listed
Lead sponsor
National Institute on Aging (NIA)
NIH
Eligibility
50 Years and older
Enrollment
88 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2009
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated May 28, 2009 · Synced Jul 20, 2026, 6:39 PM EDT
Completed Not applicable Interventional

BFRT for Severe Lower Extremity Muscle Atrophy

NCT04357184
View directory record Official record
Conditions
Severe Muscle Atrophy, Muscle Weakness
Interventions
Blood flow restriction training
Other
Lead sponsor
Cincinnati Sportsmedicine Research and Education Foundation
Other
Eligibility
Not listed
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 15, 2022 · Synced Jul 20, 2026, 6:39 PM EDT
Completed Phase 4 Interventional Results available

CESI With Low Dose Lidocaine and Transient Weakness

NCT03127137
View directory record Official record
Conditions
Cervical Radiculitis, Pain
Interventions
Experimental Group 1 triamcinolone and lidocaine, Experimental Group 2 triamcinolone and saline
Drug
Lead sponsor
Northwestern University
Other
Eligibility
18 Years and older
Enrollment
123 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Jul 20, 2026, 6:39 PM EDT
Completed Not applicable Interventional Results available

ALS and Airway Clearance (ALSAC) Therapy

NCT04947436
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis, Respiratory Muscle Weakness
Interventions
High Frequency Chest Wall Oscillation, Mechanical insufflation/exsufflation
Device
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
21 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2017
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Nov 3, 2021 · Synced Jul 20, 2026, 6:39 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Internally Versus Externally Guided Body Weight-Supported Treadmill Training (BWSTT) for Locomotor Recovery Post-stroke

NCT00125619
View directory record Official record
Conditions
Stroke
Interventions
Locomotor training
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2009
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Feb 16, 2017 · Synced Jul 20, 2026, 6:39 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Ultrasound Guided Adductor Canal Block Versus Femoral Nerve Block for Quadriceps Strength and Fall-risk

NCT01655277
View directory record Official record
Conditions
Quadriceps Muscle Weakness, Adductor Muscle Weakness, Fall Risk
Interventions
Ultrasound Guided Adductor Canal Block, Ultrasound Guided Femoral Nerve Block
Procedure
Lead sponsor
St. Luke's-Roosevelt Hospital Center
Other
Eligibility
18 Years to 65 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jul 31, 2012 · Synced Jul 20, 2026, 6:39 PM EDT
Completed Not applicable Interventional

Effectiveness of Creatine in Preventing Muscle Aching From Cholesterol-Lowering Statin Drugs

NCT00797407
View directory record Official record
Conditions
Hypercholesterolemia, Aches, Cramps, Weakness
Interventions
Creatine
Dietary Supplement
Lead sponsor
The Cleveland Clinic
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006
U.S. locations
1
States / cities
Wooster, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 24, 2008 · Synced Jul 20, 2026, 6:39 PM EDT