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ClinicalTrials.gov public records Last synced Oct 24, 2026, 1:50 AM EDT

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Showing 169–192 of 316 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Debility Clear all
Completed Not applicable Interventional Accepts healthy volunteers

Neurophysiology of Weakness and Exercise in Rotator Cuff Tendinopathy

NCT02971072
View directory record Official record
Conditions
Acute Pain, Atrophic, Goals, Impairment, Infiltration, Injury, Muscle Weakness, Pain, Pathology, Shoulder Pain, Syndrome, Tendinopathy
Interventions
Subacromial injection, Physical Therapy
Procedure · Other
Lead sponsor
University of Oregon
Other
Eligibility
21 Years to 45 Years
Enrollment
180 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2021
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 13, 2022 · Synced Oct 24, 2026, 1:50 AM EDT
Completed Not applicable Interventional Results available

Effects of Post-Stroke Upper Extremity Assistance

NCT05036642
View directory record Official record
Conditions
Arm Weakness as a Consequence of Stroke
Interventions
Compliant Passive Arm Support
Device
Lead sponsor
Stanford University
Other
Eligibility
18 Years and older
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Oct 25, 2023 · Synced Oct 24, 2026, 1:50 AM EDT
Recruiting Not applicable Interventional

At Home Wearable Sensors and Smartphone for Stroke Survivors With Upper Limb Motor Challenges.

NCT06787729
View directory record Official record
Conditions
Stroke
Interventions
mHealth
Device
Lead sponsor
Spaulding Rehabilitation Hospital
Other
Eligibility
18 Years to 80 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Charlestown, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jul 13, 2026 · Synced Oct 24, 2026, 1:50 AM EDT
Terminated Not applicable Interventional

PB125, Osteoarthritis, Pain, Mobility, and Energetics

NCT04638387
View directory record Official record
Conditions
Osteoarthritis, Knee, Muscle Weakness, Pain, Joint
Interventions
PB125, Placebo
Dietary Supplement
Lead sponsor
Colorado State University
Other
Eligibility
50 Years to 65 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Fort Collins, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 14, 2022 · Synced Oct 24, 2026, 1:50 AM EDT
Completed Not applicable Interventional

Effect of mCIMT Casting on Speech-language Outcomes in Children With Hemiparesis

NCT04259814
View directory record Official record
Conditions
Speech and Language Disorder, Cerebral Palsy, Hemiplegia, Hemiparesis
Interventions
Speech-language therapy (SLT), Modified constraint-induced movement therapy (mCIMT)
Behavioral
Lead sponsor
Shirley Ryan AbilityLab
Other
Eligibility
15 Months to 7 Years
Enrollment
3 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Sep 21, 2021 · Synced Oct 24, 2026, 1:50 AM EDT
Completed Not applicable Interventional

Quantification of the Effect of the OtoBand on Objective Measures of Vertigo and Dizziness

NCT05157399
View directory record Official record
Conditions
Dizziness, Vertigo, Vestibular Migraine, Vestibular Neuritis, Labyrinthitis
Interventions
Otoband, Placebo Device
Device
Lead sponsor
Otolith Labs
Industry
Eligibility
18 Years to 70 Years
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 15, 2022 · Synced Oct 24, 2026, 1:50 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Muscle Aging Phenotypes in Childhood Cancer Survivors

NCT07531498
View directory record Official record
Conditions
Muscle Weakness, Low Muscle Mass, Sarcopenia
Interventions
Multimodal Muscle Imaging and Functional Assessment, Multimodal Muscle Imaging and Neuromuscular Assessment, Comprehensive Muscle Phenotyping, Integrated Neuromuscular and Imaging Evaluation
Other
Lead sponsor
St. Jude Children's Research Hospital
Other
Eligibility
18 Years and older
Enrollment
533 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2031
U.S. locations
1
States / cities
Memphis, Tennessee
Source: ClinicalTrials.gov public record
Updated Sep 16, 2026 · Synced Oct 24, 2026, 1:50 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Mitigating Neural Hypoexcitability and Weakness During Disuse in Women

NCT07166198
View directory record Official record
Conditions
Muscle Weakness
Interventions
Wrist immobilization, Resistance training, Resistance training rehabilitation
Device · Behavioral
Lead sponsor
Kansas State University
Other
Eligibility
40 Years to 65 Years · Female only
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2027
U.S. locations
1
States / cities
Manhattan, Kansas
Source: ClinicalTrials.gov public record
Updated Jun 10, 2026 · Synced Oct 24, 2026, 1:50 AM EDT
Completed Not applicable Interventional

Video Game-based Therapy for Arm Weakness In Progressive Multiple Sclerosis

NCT03094364
View directory record Official record
Conditions
Primary Progressive Multiple Sclerosis, Hemiparesis
Interventions
Gaming CI Therapy
Behavioral
Lead sponsor
University of Massachusetts, Lowell
Other
Eligibility
18 Years and older
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2018
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Oct 24, 2026, 1:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Targeting Personalized Brain States Reflecting Strong and Weak Corticospinal Tract Output in Real-time

NCT06365086
View directory record Official record
Conditions
Neurotypical Adults
Interventions
Personalized brain state-dependent single-pulse TMS
Device
Lead sponsor
University of Texas at Austin
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Austin, Texas
Source: ClinicalTrials.gov public record
Updated Apr 17, 2025 · Synced Oct 24, 2026, 1:50 AM EDT
Not listed Phase 1 Interventional

Improving Ambulatory Community Access After Paralysis

NCT01570816
View directory record Official record
Conditions
Stroke, Partial Paralysis, Spinal Cord Injury, Tetraplegia, Quadriplegia
Interventions
IRS-8 (8 channel implanted receiver stimulator)
Device
Lead sponsor
Louis Stokes VA Medical Center
Federal
Eligibility
18 Years to 75 Years
Enrollment
6 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2021
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Mar 14, 2018 · Synced Oct 24, 2026, 1:50 AM EDT
Recruiting Not applicable Interventional

Passive Robots for Stroke Rehabilitation: A Feasibility Study

NCT07218276
View directory record Official record
Conditions
Stroke
Interventions
Functional Training with SepaRRo and NeuRRoFES
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 75 Years
Enrollment
4 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Nov 10, 2025 · Synced Oct 24, 2026, 1:50 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Use of Hand-held Dynamometry to Obtain Objective Measures of Lower Extremity Force Production With Chronic Stroke

NCT05941962
View directory record Official record
Conditions
Chronic Stroke, Weakness, Muscle
Interventions
Not listed
Lead sponsor
Vanderbilt University Medical Center
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Nashville, Tennessee
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Oct 24, 2026, 1:50 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

FIT Exercise in 30d of ULLS-induced Muscle Disuse

NCT06631053
View directory record Official record
Conditions
Muscle Atrophy, Muscle Weakness
Interventions
velocity-based FIT (VBFIT), No Exercise
Other
Lead sponsor
Lance Bollinger
Other
Eligibility
35 Years to 45 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Source: ClinicalTrials.gov public record
Updated Oct 24, 2025 · Synced Oct 24, 2026, 1:50 AM EDT
Active, not recruiting Early Phase 1 Interventional

Memantine for Enhanced Stroke Recovery

NCT02144584
View directory record Official record
Conditions
Ischemic Stroke, Upper Extremity Weakness
Interventions
Memantine XR, Placebo (for memantine)
Drug
Lead sponsor
University of Utah
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2027
U.S. locations
1
States / cities
Salt Lake City, Utah
Source: ClinicalTrials.gov public record
Updated Aug 27, 2026 · Synced Oct 24, 2026, 1:50 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Systematized Quality Exercise Alternatives for Stress Incontinence

NCT03443687
View directory record Official record
Conditions
Stress Urinary Incontinence, Pelvic Floor; Weak, Incontinence, Urinary, Quality of Life
Interventions
Pelvic Floor Physical Therapy, Home Biofeedback
Behavioral · Device
Lead sponsor
University of New Mexico
Other
Eligibility
18 Years and older · Female only
Enrollment
54 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Albuquerque, New Mexico
Source: ClinicalTrials.gov public record
Updated Dec 21, 2023 · Synced Oct 24, 2026, 1:50 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Lateral Neck Flexor Endurance and Hyperlaxity

NCT04770987
View directory record Official record
Conditions
Physical Endurance, Hypermobility, Joint, Muscular Weakness
Interventions
lateral neck flexor endurance test
Other
Lead sponsor
University of Hartford
Other
Eligibility
18 Years to 60 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021
U.S. locations
1
States / cities
West Hartford, Connecticut
Source: ClinicalTrials.gov public record
Updated Jul 22, 2021 · Synced Oct 24, 2026, 1:50 AM EDT
Recruiting No phase listed Observational Accepts healthy volunteers

Developing New Ways to Detect Respiratory Impairment Early in ALS

NCT07844590
View directory record Official record
Conditions
Amyotrophic Lateral Sclerosis (ALS)
Interventions
Not listed
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Sep 28, 2026 · Synced Oct 24, 2026, 1:50 AM EDT
Terminated Phase 1Phase 2 Interventional Results available

Luveltamab Tazevibulin (STRO-002) in Infants and Children < 12 Years of Age With Relapsed/Refractory CBFA2T3::GLIS2 AML

NCT06679582
View directory record Official record
Conditions
Acute Myeloid Leukemia (AML)
Interventions
Luveltamab tazevibulin
Drug
Lead sponsor
Sutro Biopharma, Inc.
Industry
Eligibility
1 Day to 12 Years
Enrollment
1 participant
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
23
States / cities
Birmingham, Alabama • Los Angeles, California • Palo Alto, California + 19 more
Source: ClinicalTrials.gov public record
Updated Oct 13, 2026 · Synced Oct 24, 2026, 1:50 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Physiology of Weakness in Movement Disorders

NCT00307346
View directory record Official record
Conditions
Movement Disorders
Interventions
Not listed
Lead sponsor
National Institute of Neurological Disorders and Stroke (NINDS)
NIH
Eligibility
18 Years to 80 Years
Enrollment
6 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
1
States / cities
Bethesda, Maryland
Source: ClinicalTrials.gov public record
Updated Jul 2, 2017 · Synced Oct 24, 2026, 1:50 AM EDT
Completed Not applicable Interventional

Does Blood Vessel Vasodilation, Caused by Focal Infiltration of Lidocaine Cause Temporary Nerve Functional Recovery for Patients with Common Peroneal Nerve Injury or Entrapment: Testing the 'Phoenix Sign' Effect Between Lidocaine (a Common Local Anesthetic) and Papaverine, a Know Vasodilator

NCT06637046
View directory record Official record
Conditions
Drop Foot
Interventions
Diagnostic procedures, Lidocaine HCl
Diagnostic Test
Lead sponsor
Stephen Barrett
Other
Eligibility
18 Years to 85 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Marietta, Georgia
Source: ClinicalTrials.gov public record
Updated Oct 15, 2024 · Synced Oct 24, 2026, 1:50 AM EDT
Completed Phase 3 Interventional Results available

An Efficacy and Safety Study of ARGX-113 in Patients With Myasthenia Gravis Who Have Generalized Muscle Weakness

NCT03669588
View directory record Official record
Conditions
Generalized Myasthenia Gravis
Interventions
ARGX-113, Placebo
Biological
Lead sponsor
argenx
Industry
Eligibility
18 Years and older
Enrollment
167 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2020
U.S. locations
25
States / cities
Phoenix, Arizona • Carlsbad, California • Los Angeles, California + 21 more
Source: ClinicalTrials.gov public record
Updated Feb 8, 2022 · Synced Oct 24, 2026, 1:50 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Movement-Based Pelvic Health Education for Women in Underserved Communities

NCT05569694
View directory record Official record
Conditions
Pelvic Floor Muscle Weakness, Pelvic Pain
Interventions
Movement-based pelvic health education
Other
Lead sponsor
Arkansas Colleges of Health Education
Other
Eligibility
18 Years to 100 Years · Female only
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2024
U.S. locations
1
States / cities
Fort Smith, Arkansas
Source: ClinicalTrials.gov public record
Updated Jul 24, 2023 · Synced Oct 24, 2026, 1:50 AM EDT
Recruiting Not applicable Interventional

Occupational Therapy and Registered Dietitian Services to Reduce Fall Risk Among Home Delivered Meal Clients

NCT06586970
View directory record Official record
Conditions
Diet, Food and Nutrition, Accidental Falls, Cardiovascular Diseases, Diabetes, Debility, Frailty, Functional Disability
Interventions
Meals + RD services, Meals + OT services, Meals + RD + OT services
Behavioral
Lead sponsor
Ohio State University
Other
Eligibility
60 Years and older
Enrollment
750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Apr 13, 2026 · Synced Oct 24, 2026, 1:50 AM EDT