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ClinicalTrials.gov public records Last synced Oct 21, 2026, 4:01 AM EDT

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Showing 145–168 of 241 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Decay Clear all
Withdrawn Not applicable Interventional Accepts healthy volunteers

Microbial Testing for Caries Risk Assessment

NCT03389373
View directory record Official record
Conditions
Dental Caries
Interventions
GC Strep Mutans Saliva Sampling
Device
Lead sponsor
University of Colorado, Denver
Other
Eligibility
24 Months to 96 Months
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Jul 16, 2018 · Synced Oct 21, 2026, 4:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Development of a Web-Based Course to Maintain Skills in Nurses Trained to Screen for Dysphagia

NCT00570557
View directory record Official record
Conditions
Deglutition Disorders, Dysphagia, Stroke
Interventions
TOR-BSST© Refresher Training
Other
Lead sponsor
University Health Network, Toronto
Other
Eligibility
Not listed
Enrollment
96 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2011
U.S. locations
1
States / cities
Binghamton, New York
Source: ClinicalTrials.gov public record
Updated Jan 11, 2012 · Synced Oct 21, 2026, 4:01 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers

Evaluation of a Brief Tailored Motivational Intervention to Prevent Early Childhood Caries

NCT01123330
View directory record Official record
Conditions
Dental Caries
Interventions
Motivational Interviewing
Behavioral
Lead sponsor
Temple University
Other
Eligibility
Up to 5 Years
Enrollment
2,042 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2001 – 2007
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated May 14, 2010 · Synced Oct 21, 2026, 4:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

TEACH: Technology Evaluation to Address Child Health

NCT02912000
View directory record Official record
Conditions
Smoking, Obesity, Dental Caries
Interventions
TEACH intervention
Behavioral
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years and older
Enrollment
650 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Mar 22, 2018 · Synced Oct 21, 2026, 4:01 AM EDT
Completed Phase 4 Interventional Results available

The Effect of Silver Diamine Fluoride (SDF) on Bacteria Involved in Root or Cervical Carious Lesions

NCT02953886
View directory record Official record
Conditions
Caries
Interventions
Silver Diamine Fluoride (SDF)
Device
Lead sponsor
Heba Mitwalli
Other
Eligibility
18 Years and older
Enrollment
21 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Sep 28, 2018 · Synced Oct 21, 2026, 4:01 AM EDT
Recruiting Phase 2 Interventional Accepts healthy volunteers

Autologous Volar Fibroblast Injection Into the Stump Site of Amputees

NCT03947450
View directory record Official record
Conditions
Amputation, Skin Wound, Stem Cell
Interventions
Autologous Skin Fibroblasts, Placebo
Biological
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 65 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2028
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 9, 2026 · Synced Oct 21, 2026, 4:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Predicting Caries Risk in Underserved Toddlers in Primary Healthcare Settings

NCT01707797
View directory record Official record
Conditions
Dental Caries
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
9 Months to 15 Months
Enrollment
1,326 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2017
U.S. locations
3
States / cities
Indianapolis, Indiana • Iowa City, Iowa • Durham, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 17, 2018 · Synced Oct 21, 2026, 4:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

DPBRN Patient Satisfaction With Dental Restorations

NCT01201421
View directory record Official record
Conditions
Patient Satisfaction
Interventions
Not listed
Lead sponsor
Dental Practice-Based Research Network
Network
Eligibility
13 Years and older
Enrollment
5,932 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
6
States / cities
Birmingham, Alabama • Gainesville, Florida • Minneapolis, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Jun 16, 2011 · Synced Oct 21, 2026, 4:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

DPBRN Longitudinal Study of Questionable Occlusal Caries Lesions

NCT01309971
View directory record Official record
Conditions
Dental Caries
Interventions
Not listed
Lead sponsor
Dental Practice-Based Research Network
Network
Eligibility
6 Years and older
Enrollment
2,624 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2011
U.S. locations
6
States / cities
Birmingham, Alabama • Gainesville, Florida • Minneapolis, Minnesota + 1 more
Source: ClinicalTrials.gov public record
Updated Feb 19, 2014 · Synced Oct 21, 2026, 4:01 AM EDT
Completed Phase 2 Interventional Accepts healthy volunteers Results available

Pharmacokinetics of Advantage Arrest

NCT04184271
View directory record Official record
Conditions
Dental Caries
Interventions
38% silver diamine fluoride
Drug
Lead sponsor
Advantage Silver Dental Arrest, LLC
Industry
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Jan 26, 2021 · Synced Oct 21, 2026, 4:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Older Adult Effectiveness of 2 Treatments

NCT03916926
View directory record Official record
Conditions
Dental Caries
Interventions
A "simple medical strategy" consisting of silver diamine fluoride (SDF), B "typical dental strategy" consisting of atraumatic restorative treatment (ART) with glass ionomer cement + Fluoride varnish (FV)
Device
Lead sponsor
Case Western Reserve University
Other
Eligibility
62 Years and older
Enrollment
568 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2024
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 13, 2025 · Synced Oct 21, 2026, 4:01 AM EDT
Not listed No phase listed Observational

Observational Evaluation of the Peristomal Skin Condition in Ostomates

NCT01526967
View directory record Official record
Conditions
Ostomy
Interventions
Not listed
Lead sponsor
ConvaTec Inc.
Industry
Eligibility
18 Years and older
Enrollment
2,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
13
States / cities
Tucson, Arizona • Concord, California • Plymoth, Connecticut + 10 more
Source: ClinicalTrials.gov public record
Updated Dec 17, 2012 · Synced Oct 21, 2026, 4:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healthy Hydration Pilot in Elementary Schools

NCT06132763
View directory record Official record
Conditions
Hydration, Dental Caries, Body Mass Index
Interventions
Hydration Intervention, Control - Assessments Only
Behavioral · Other
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
4 Years and older
Enrollment
563 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Oct 31, 2025 · Synced Oct 21, 2026, 4:01 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Extending Dental Care to Nursing Home Residents to Reduce Mouth Infections and Incidence of Pneumonia and Improve Diabetic Glucose Control

NCT06890676
View directory record Official record
Conditions
Periodontitis, Gingivitis, Periodontal Disease, Periodontal Infections, Oral Infections, Periapical Infections, Pneumonia, Diabetes
Interventions
Comprehensive Oral Evaluation, Intraoral Complete Radiographic Series, • Teledentistry-synchronous and asynchronous, Periodontal Therapy, Periodontal Maintenance Procedure, Application of Caries Arresting Medicament, Oral Hygiene Assistance, Referral for Treatment of Acute Oral Infection
Other · Procedure
Lead sponsor
Missouri Department of Health and Senior Services
Other
Eligibility
60 Years to 100 Years
Enrollment
150 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Jefferson City, Missouri
Source: ClinicalTrials.gov public record
Updated Mar 26, 2025 · Synced Oct 21, 2026, 4:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Conventional Bite Wing Radiography Versus Stationary Intraoral Tomosynthesis, a Comparison Study

NCT02873585
View directory record Official record
Conditions
Dental Caries
Interventions
Stationary intraoral tomosynthesis, Standard conventional bitewing radiography
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years and older
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Sep 2, 2020 · Synced Oct 21, 2026, 4:01 AM EDT
Terminated Phase 2 Interventional Results available

Treatment of Septic Shock by Inhibiting Autodigestion and Preserving Gut Integrity With Enteric LB1148

NCT02317549
View directory record Official record
Conditions
Septic Shock
Interventions
LB1148, Placebo
Drug
Lead sponsor
Leading BioSciences, Inc
Industry
Eligibility
18 Years to 75 Years
Enrollment
8 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2016
U.S. locations
26
States / cities
Mobile, Alabama • Fresno, California • Long Beach, California + 23 more
Source: ClinicalTrials.gov public record
Updated Jun 1, 2020 · Synced Oct 21, 2026, 4:01 AM EDT
Completed Not applicable Interventional Results available

Short-term Disulfiram Administration to Accelerate the Decay of the HIV Reservoir in Antiretroviral-treated HIV Infected Individuals

NCT01286259
View directory record Official record
Conditions
HIV-1 Infection
Interventions
Disulfiram
Drug
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
2
States / cities
San Francisco, California • Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Jun 30, 2020 · Synced Oct 21, 2026, 4:01 AM EDT
Completed Not applicable Interventional Results available

TetricCAD Crown Clinical Study

NCT03716817
View directory record Official record
Conditions
Fractured Tooth, Decayed Tooth, Unsatisfactory Restoration of Tooth
Interventions
Tetric CAD
Device
Lead sponsor
University of Michigan
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2024
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 28, 2026 · Synced Oct 21, 2026, 4:01 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

The Use of Medical Grade Honey in the Prevention of Bone Anchored Hearing Aid Associated Skin Breakdown

NCT03929224
View directory record Official record
Conditions
Skin Infection
Interventions
Medicinal honey, Bacitracin
Drug
Lead sponsor
Henry Ford Health System
Other
Eligibility
18 Years to 100 Years
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2020
U.S. locations
1
States / cities
Novi, Michigan
Source: ClinicalTrials.gov public record
Updated Jan 7, 2026 · Synced Oct 21, 2026, 4:01 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Decision Aids for the Management of Suspicious Occlusal Caries Lesions

NCT02340767
View directory record Official record
Conditions
Dental Caries
Interventions
Spectra Device, DIAGNOdent
Device
Lead sponsor
The National Dental Practice-Based Research Network
Network
Eligibility
6 Years and older
Enrollment
3,085 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
6
States / cities
Birmingham, Alabama • Gainesville, Florida • Minneapolis, Minnesota + 3 more
Source: ClinicalTrials.gov public record
Updated Apr 3, 2019 · Synced Oct 21, 2026, 4:01 AM EDT
Recruiting Not applicable Interventional

Artificial Intelligence (AI) for Proximal Caries Detection and Its Impact on Treatment Threshold

NCT07648212
View directory record Official record
Conditions
Caries,Dental
Interventions
Review of Radiograph Images
Other
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 99 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Oct 14, 2026 · Synced Oct 21, 2026, 4:01 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Shifts in the Oral Biofilm of Patients With Known Oral Health Risk Factors

NCT02885064
View directory record Official record
Conditions
Dental Caries, Gingivitis
Interventions
Not listed
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
8 Years to 99 Years
Enrollment
34 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2021
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Source: ClinicalTrials.gov public record
Updated Dec 14, 2021 · Synced Oct 21, 2026, 4:01 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Maximal Use Study to Determine the Pharmacokinetics of L-arginine After Exaggerated Oral Use of COL101

NCT06182267
View directory record Official record
Conditions
Caries,Dental
Interventions
L Arginine, Sodium Fluoride
Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 65 Years
Enrollment
29 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023
U.S. locations
1
States / cities
Fair Lawn, New Jersey
Source: ClinicalTrials.gov public record
Updated Jan 2, 2024 · Synced Oct 21, 2026, 4:01 AM EDT
Completed Not applicable Interventional

CATCH Healthy Smiles:An Elementary School Oral Health Intervention Trial

NCT04632667
View directory record Official record
Conditions
Caries,Dental
Interventions
Comparison School Group, Intervention School Group
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
5 Years to 9 Years
Enrollment
1,084 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Oct 21, 2026, 4:01 AM EDT