- Conditions
- Acute Decompensated Heart Failure
- Interventions
- Daily pocus exam
- Diagnostic Test
- Lead sponsor
- Riverside University Health System Medical Center
- Other
- Eligibility
- 18 Years to 95 Years
- Enrollment
- 400 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 1
- States / cities
- Moreno Valley, California
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Showing 1–24
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- Conditions
- Heart Failure
- Interventions
- Stepped pharmacologic care, Ultrafiltration
- Drug · Device
- Lead sponsor
- Duke University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 188 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 8
- States / cities
- Phoenix, Arizona • Atlanta, Georgia • Minneapolis, Minnesota + 5 more
- Conditions
- Chronic Heart Failure
- Interventions
- conivaptan, placebo
- Drug
- Lead sponsor
- Cumberland Pharmaceuticals
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 170 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2002 – 2004
- U.S. locations
- 26
- States / cities
- Huntsville, Alabama • Los Angeles, California • Manteca, California + 22 more
- Conditions
- Heart Failure, Congestive
- Interventions
- ZP120, I.v. catherization, 6-minutes walk performance, Dyspnea severity assessment, Blood sampling for laboratory tests, ECG, Physical examination
- Drug · Procedure · Behavioral
- Lead sponsor
- Zealand Pharma
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 130 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006
- U.S. locations
- 22
- States / cities
- Los Angeles, California • San Diego, California • San Francisco, California + 17 more
- Conditions
- Obstructive Sleep Apnea, Heart Failure; With Decompensation
- Interventions
- Not listed
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2021
- U.S. locations
- 2
- States / cities
- San Diego, California
- Conditions
- Acute Decompensated Heart Failure
- Interventions
- loop diuretic, tolvaptan, ultrafiltration
- Drug · Procedure
- Lead sponsor
- The Christ Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 45 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 1
- States / cities
- Cincinnati, Ohio
- Conditions
- Acute Decompensated Heart Failure
- Interventions
- TRV027 Dose #1, TRV027 Dose #2, TRV027 Dose #3, Placebo
- Drug
- Lead sponsor
- Trevena Inc.
- Industry
- Eligibility
- 21 Years to 85 Years
- Enrollment
- 620 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 4
- States / cities
- Detroit, Michigan • Cincinnati, Ohio • Tullahoma, Tennessee + 1 more
- Conditions
- Acute Heart Failure
- Interventions
- Cinaciguat (BAY58-2667), Placebo
- Drug
- Lead sponsor
- Bayer
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 6
- States / cities
- Ridgewood, New Jersey • Winston-Salem, North Carolina • Cleveland, Ohio + 2 more
- Conditions
- Heart Failure, Congestive
- Interventions
- Ularitide
- Drug
- Lead sponsor
- Facet Biotech
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- U.S. locations
- 8
- States / cities
- San Diego, California • Atlanta, Georgia • Chicago, Illinois + 5 more
- Conditions
- Acute Decompensated Heart Failure
- Interventions
- Not listed
- Lead sponsor
- Abbott RDx Cardiometabolic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 231 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2010
- U.S. locations
- 3
- States / cities
- San Diego, California • Brooklyn, New York • Columbus, Ohio
- Conditions
- Heart Failure, Acute Heart Failure (AHF), Chronic Heart Failure
- Interventions
- Not listed
- Lead sponsor
- Fundacion Clinica Valle del Lili
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 6,732 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 2
- States / cities
- Manhasset, New York • Dallas, Texas
- Conditions
- Acute Decompensated Heart Failure
- Interventions
- Doraya Catheter
- Device
- Lead sponsor
- Revamp Medical Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 21 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2026
- U.S. locations
- 14
- States / cities
- San Francisco, California • Weston, Florida • Augusta, Georgia + 9 more
- Conditions
- Heart Failure
- Interventions
- μCor
- Device
- Lead sponsor
- Zoll Medical Corporation
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 265 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 67
- States / cities
- Sheffield, Alabama • El Cajon, California • Inglewood, California + 60 more
- Conditions
- Acute Decompensated Heart Failure
- Interventions
- multi-domain rehabilitation intervention, Attention Control
- Behavioral
- Lead sponsor
- Wake Forest University Health Sciences
- Other
- Eligibility
- 60 Years and older
- Enrollment
- 349 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2020
- U.S. locations
- 3
- States / cities
- Durham, North Carolina • Winston-Salem, North Carolina • Philadelphia, Pennsylvania
- Conditions
- Heart Failure, Transplant; Failure, Heart, Decompensated Heart Failure, Fibrosis, Liver, Cirrhosis, Liver
- Interventions
- Not listed
- Lead sponsor
- Baylor Research Institute
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 14 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Dallas, Texas
- Conditions
- Sleep Apnea, Congestive Heart Failure, Heart Failure
- Interventions
- Not listed
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1,600 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2013
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Acute Decompensated Heart Failure
- Interventions
- High-dose furosemide, Low-dose furosemide, Low-dose furosemide combined with low-dose dopamine
- Drug
- Lead sponsor
- Larissa University Hospital
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 161 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2013
- U.S. locations
- 2
- States / cities
- Atlanta, Georgia • Cleveland, Ohio
- Conditions
- Congestive Heart Failure
- Interventions
- Placebo, Cinaciguat (BAY58-2667)
- Drug
- Lead sponsor
- Bayer
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2009
- U.S. locations
- 6
- States / cities
- San Diego, California • Washington D.C., District of Columbia • Boston, Massachusetts + 3 more
- Conditions
- Acute Decompensated Heart Failure
- Interventions
- Neuromodulation
- Device
- Lead sponsor
- University of Oklahoma
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2026
- U.S. locations
- 1
- States / cities
- Oklahoma City, Oklahoma
- Conditions
- Acute Decompensated Heart Failure
- Interventions
- Atibuclimab (IC14)
- Drug
- Lead sponsor
- Implicit Bioscience
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 10 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2026
- U.S. locations
- 2
- States / cities
- Charlottesville, Virginia • Richmond, Virginia
- Conditions
- Acute Decompensated Heart Failure
- Interventions
- Spironolactone and patiromer
- Drug
- Lead sponsor
- The University of Texas Health Science Center at San Antonio
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- San Antonio, Texas
- Conditions
- Heart Failure
- Interventions
- Not listed
- Lead sponsor
- Noah Labs
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 70 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Acute Decompensated Heart Failure, Obstructive Sleep Apnea, Motivational Enhancement, PAP Adherence
- Interventions
- Telemedicine Intensive Motivational Enhancement
- Behavioral
- Lead sponsor
- The Cleveland Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2025
- U.S. locations
- 1
- States / cities
- Cleveland, Ohio
- Conditions
- Heart Failure, Decompensated Heart Failure, Hospital Length of Stay
- Interventions
- Point-of-Care Ultrasound (POCUS)
- Device
- Lead sponsor
- Florida International University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 66 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 1
- States / cities
- Miami, Florida