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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Filters: Condition: Defecation Function Clear all
Completed Phase 1 Interventional Accepts healthy volunteers

Influence of a Delivery System on the Efficacy of a Probiotic Intervention

NCT01399996
View directory record Official record
Conditions
Delayed Transit Time, Irregular Bowel Function
Interventions
Yogurt smoothie without probiotic, Yogurt smoothie with probiotic added post fermentation, Yogurt smoothie with probiotic added pre-fermentation, A capsule containing the probiotic
Dietary Supplement
Lead sponsor
Penn State University
Other
Eligibility
18 Years to 40 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2014
U.S. locations
1
States / cities
University Park, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 20, 2023 · Synced Sep 4, 2026, 2:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Effect of Preoperative Fiber on Postoperative Bowel Function

NCT04882995
View directory record Official record
Conditions
Constipation, Prolapse, Vaginal
Interventions
Psyillium fiber
Dietary Supplement
Lead sponsor
University of Massachusetts, Worcester
Other
Eligibility
18 Years and older · Female only
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Worcester, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 27, 2022 · Synced Sep 4, 2026, 2:15 AM EDT
Active, not recruiting Not applicable Interventional

Electrical Stimulation for Continence After Spinal Cord Injury

NCT02978638
View directory record Official record
Conditions
Spinal Cord Injury, Neurogenic Bladder, Incontinence
Interventions
Finetech Vocare Bladder System
Device
Lead sponsor
Palo Alto Veterans Institute for Research
Other
Eligibility
22 Years and older
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2025
U.S. locations
4
States / cities
Palo Alto, California • San Jose, California • Albuquerque, New Mexico + 1 more
Source: ClinicalTrials.gov public record
Updated Aug 2, 2025 · Synced Sep 4, 2026, 2:15 AM EDT
Withdrawn No phase listed Observational

A Non-Interventional Pilot Study to Explore the Role of Gut Flora in IBS

NCT04214470
View directory record Official record
Conditions
Irritable Bowel, Irritable Bowel Syndrome, Irritable Bowel Syndrome With Diarrhea, Irritable Bowel Syndrome Mixed, Irritable Bowel Syndrome With Constipation, Irritable Bowel Syndrome Without Diarrhea, Irritable Bowel Syndrome Aggravated, Irritable Bowel Syndrome Characterized by Constipation, Irritable Bowel Syndrome Characterised by Alternating Bowel Habit
Interventions
No intervention
Other
Lead sponsor
ProgenaBiome
Other
Eligibility
Not listed
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2030
U.S. locations
1
States / cities
Ventura, California
Source: ClinicalTrials.gov public record
Updated Jun 4, 2025 · Synced Sep 4, 2026, 2:15 AM EDT
Completed Phase 4 Interventional Results available

Efficacy of IV Acetaminophen for Pain Management

NCT02028715
View directory record Official record
Conditions
Post-operative Pain
Interventions
Placebo, IV acetaminophen
Drug
Lead sponsor
Aultman Health Foundation
Other
Eligibility
18 Years to 85 Years · Female only
Enrollment
68 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Canton, Ohio
Source: ClinicalTrials.gov public record
Updated Jan 15, 2019 · Synced Sep 4, 2026, 2:15 AM EDT
Completed Not applicable Interventional Results available

A Colonic Tube to Improve Bowel Function in Spinal Cord Injury

NCT00345397
View directory record Official record
Conditions
Constipation, Fecal Incontinence, Spinal Cord Injury
Interventions
Percutaneous endoscopic colostomy (PEC) tube
Device
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years and older
Enrollment
7 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2018
U.S. locations
1
States / cities
Milwaukee, Wisconsin
Source: ClinicalTrials.gov public record
Updated Jan 31, 2019 · Synced Sep 4, 2026, 2:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Intravenous Lidocaine for Cystectomy Procedures

NCT02924480
View directory record Official record
Conditions
Invasive Bladder Cancer
Interventions
Cystectomy, Lidocaine, Saline
Procedure · Drug
Lead sponsor
CAMC Health System
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Charleston, West Virginia
Source: ClinicalTrials.gov public record
Updated Mar 8, 2022 · Synced Sep 4, 2026, 2:15 AM EDT
Not listed Not applicable Interventional

Trancutaneous Abdominal Stimulation on Bowel Function.

NCT04627168
View directory record Official record
Conditions
Spinal Cord Injuries, Constipation
Interventions
Non-invasive, surface electrical stimulation device, DS5 Digitimer
Device
Lead sponsor
Amol Soin, M.D., MBA
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2023
U.S. locations
1
States / cities
Dayton, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 12, 2022 · Synced Sep 4, 2026, 2:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Safety Evaluation of a Diet and Nutritional Supplementation Program- Purify 2.0

NCT03685552
View directory record Official record
Conditions
Gastrointestinal Symptoms
Interventions
Prog: Purify-2
Other
Lead sponsor
Nature's Sunshine Products, Inc.
Industry
Eligibility
18 Years to 69 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Lehi, Utah
Source: ClinicalTrials.gov public record
Updated Sep 25, 2018 · Synced Sep 4, 2026, 2:15 AM EDT
Recruiting Not applicable Interventional

A Study of Herbal Supplements in Cancer Survivors With Constipation

NCT07091084
View directory record Official record
Conditions
Constipation, Cancer, Functional Constipation
Interventions
MZRW
Dietary Supplement
Lead sponsor
Memorial Sloan Kettering Cancer Center
Other
Eligibility
18 Years and older
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
7
States / cities
Basking Ridge, New Jersey • Middletown, New Jersey • Montvale, New Jersey + 4 more
Source: ClinicalTrials.gov public record
Updated May 21, 2026 · Synced Sep 4, 2026, 2:15 AM EDT
Completed Not applicable Interventional

The Effect of Coffee After Resection of Small Bowel

NCT03143621
View directory record Official record
Conditions
Postoperative Ileus
Interventions
Coffee, Water
Dietary Supplement · Other
Lead sponsor
Mount Carmel Health System
Other
Eligibility
18 Years to 100 Years
Enrollment
79 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Aug 15, 2023 · Synced Sep 4, 2026, 2:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resistant Maltodextrin Supplementation: Gastrointestinal Health

NCT02733263
View directory record Official record
Conditions
Healthy
Interventions
15 g RMD, 25 g RMD, 0 g RMD
Dietary Supplement
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 50 Years
Enrollment
64 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 1, 2018 · Synced Sep 4, 2026, 2:15 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Curcumin (Tumeric) in the Treatment of Irritable Bowel Syndrome: A Randomized-Controlled Trial

NCT00779493
View directory record Official record
Conditions
Irritable Bowel Syndrome
Interventions
curcumin, placebo
Dietary Supplement
Lead sponsor
Kaiser Permanente
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Mar 10, 2015 · Synced Sep 4, 2026, 2:15 AM EDT
Terminated Phase 3 Interventional Results available

A Study to Evaluate LB1148 for Return of Bowel Function in Subjects Undergoing Bowel Resection

NCT05470387
View directory record Official record
Conditions
Ileus, Gastro-Intestinal Disorder
Interventions
LB1148, Placebo
Drug
Lead sponsor
Palisade Bio
Industry
Eligibility
18 Years to 80 Years
Enrollment
23 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
23
States / cities
Mobile, Alabama • La Jolla, California • Orange, California + 19 more
Source: ClinicalTrials.gov public record
Updated Jun 12, 2024 · Synced Sep 4, 2026, 2:15 AM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Transverse Abdominal Plane Anesthesia for Abdominal Wall Reconstruction

NCT02274077
View directory record Official record
Conditions
Hernia, Ventral
Interventions
EXPAREL, Normal Saline
Drug
Lead sponsor
Chester Mays
Other
Eligibility
18 Years and older
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2017
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Jul 10, 2016 · Synced Sep 4, 2026, 2:15 AM EDT
Recruiting Not applicable Interventional

Intra-Corporeal Anastomosis Result in Quicker Return of Bowel Function/Earlier Discharge

NCT03862781
View directory record Official record
Conditions
Colorectal Disorders
Interventions
Right Hemicolectomy
Procedure
Lead sponsor
Corewell Health West
Other
Eligibility
18 Years and older
Enrollment
125 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Grand Rapids, Michigan
Source: ClinicalTrials.gov public record
Updated Jul 19, 2026 · Synced Sep 4, 2026, 2:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Return of Bowel Function After One or Two Level Anterior Lumbar Interbody Fusion With Chewing Gum

NCT03945461
View directory record Official record
Conditions
Spondylosis, Spondylolisthesis, Neurogenic Claudication, Foraminal Stenosis
Interventions
Chewing gum
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 85 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2023
U.S. locations
1
States / cities
Phoenix, Arizona
Source: ClinicalTrials.gov public record
Updated Apr 25, 2024 · Synced Sep 4, 2026, 2:15 AM EDT
Completed Not applicable Interventional

Mindfulness-Based Eating in Patients With Irritable Bowel Syndrome

NCT02681666
View directory record Official record
Conditions
Abdominal Pain, Irritable Bowel Syndrome, IBS
Interventions
Dietary intervention, Irritable Bowel Syndrome eating awareness training
Dietary Supplement · Behavioral
Lead sponsor
University of Miami
Other
Eligibility
18 Years and older
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jun 11, 2018 · Synced Sep 4, 2026, 2:15 AM EDT
Withdrawn Not applicable Interventional

The Influence of Ambulation on the Return of Bowel Function After Colorectal Surgery

NCT01241123
View directory record Official record
Conditions
Return of Bowel Function After Colon Surgery
Interventions
Ambulation regimen, Sitz-Markers, Daily abdominal x-rays, pedometers
Procedure · Drug · Radiation + 1 more
Lead sponsor
United States Naval Medical Center, Portsmouth
Federal
Eligibility
17 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Portsmouth, Virginia
Source: ClinicalTrials.gov public record
Updated Jul 28, 2025 · Synced Sep 4, 2026, 2:15 AM EDT
Completed Not applicable Interventional

The Effect of Coffee Consumption in Enhancing Recovery of Bowel Function Following Colorectal Surgery.

NCT02639728
View directory record Official record
Conditions
Postoperative Ileus
Interventions
Regular Coffee, Decaffeinated coffee, Warm water
Other
Lead sponsor
Cedars-Sinai Medical Center
Other
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 20, 2022 · Synced Sep 4, 2026, 2:15 AM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Postoperative Gastric Point of Care Ultrasound (G-POCUS) in Abdominal Surgery

NCT05796063
View directory record Official record
Conditions
Ileus Postoperative, Postoperative Nausea and Vomiting
Interventions
gastric point of care ultrasound
Diagnostic Test
Lead sponsor
Thomas Jefferson University
Other
Eligibility
18 Years and older
Enrollment
128 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Apr 6, 2023 · Synced Sep 4, 2026, 2:15 AM EDT
Completed Phase 2 Interventional Results available

Does Welchol (Colesevelam Hydrochloride) Improve Colonic Transit in Diarrhea-predominant Irritable Bowel Syndrome (D-IBS)?

NCT00911612
View directory record Official record
Conditions
Irritable Bowel Syndrome, Diarrhea
Interventions
Colesevelam, Placebo
Drug
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years to 65 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 3, 2012 · Synced Sep 4, 2026, 2:15 AM EDT
Completed Not applicable Interventional Results available

Utility of an Animated Bowel Biofeedback Training Routine to Improve Bowel Function in Individuals With SCI

NCT02406859
View directory record Official record
Conditions
Spinal Cord Injury, Constipation, Fecal Incontinence, Neurogenic Bowel
Interventions
Bowel Biofeedback, Anorectal Manometry
Behavioral
Lead sponsor
VA Office of Research and Development
Federal
Eligibility
18 Years to 75 Years
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2017
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 16, 2021 · Synced Sep 4, 2026, 2:15 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Bowel Function After Minimally Invasive Urogynecologic Surgery

NCT01044212
View directory record Official record
Conditions
Functional Disorder of Intestine
Interventions
Docusate, Bowel medications
Drug
Lead sponsor
University of Rochester
Other
Eligibility
18 Years to 89 Years · Female only
Enrollment
72 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Oct 20, 2015 · Synced Sep 4, 2026, 2:15 AM EDT