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ClinicalTrials.gov public records Last synced Oct 20, 2026, 10:45 AM EDT

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Showing 1–24 of 41 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Defiant Disorder, Oppositional Clear all
Completed Phase 3 Interventional Accepts healthy volunteers

Parent Training to Promote Early Identification and Treatment of Childhood Behavioral Disorders

NCT00402857
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity, Attention Deficit and Disruptive Behavior Disorders
Interventions
Incredible Years Program
Behavioral
Lead sponsor
Tufts Medical Center
Other
Eligibility
22 Months to 38 Months
Enrollment
345 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2011
U.S. locations
9
States / cities
Chelsea, Massachusetts • Dorchester, Massachusetts • Jamaica Plain, Massachusetts + 6 more
Source: ClinicalTrials.gov public record
Updated Feb 12, 2013 · Synced Oct 20, 2026, 10:45 AM EDT
Completed Not applicable Interventional Results available

Adapting a Web-Based Professional Development for Mexican School Mental Health Providers Delivering Evidence-Based Intervention for ADHD and ODD

NCT05425966
View directory record Official record
Conditions
ADHD, Oppositional Defiant Disorder
Interventions
CLS-R-FUERTE
Behavioral
Lead sponsor
University of California, San Francisco
Other
Eligibility
5 Years and older
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Mar 18, 2024 · Synced Oct 20, 2026, 10:45 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Study of Cognition and Control in Youths

NCT03393390
View directory record Official record
Conditions
Attention Deficit Hyperactivity Disorder, Oppositional Defiant Disorder, Conduct Disorder
Interventions
Clinical Assessment Visit, fMRI scan
Diagnostic Test · Other
Lead sponsor
University of Michigan
Other
Eligibility
6 Years to 18 Years
Enrollment
256 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Apr 14, 2022 · Synced Oct 20, 2026, 10:45 AM EDT
Completed Phase 1 Interventional

Task-Based Grounding Program

NCT04648553
View directory record Official record
Conditions
Aggressive, Defiant Disorder, Oppositional, Attention Deficit Hyperactivity Disorder
Interventions
Task-Based Grounding, Connected Care (Enhanced Treatment as usual)
Behavioral
Lead sponsor
Dartmouth-Hitchcock Medical Center
Other
Eligibility
9 Years and older
Enrollment
28 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
1
States / cities
Lebanon, New Hampshire
Source: ClinicalTrials.gov public record
Updated Nov 8, 2021 · Synced Oct 20, 2026, 10:45 AM EDT
Completed Not applicable Interventional

Anger Control Training for Youth With Tourette Syndrome

NCT00486551
View directory record Official record
Conditions
Tourette Syndrome, Chronic Tic Disorder, Oppositional Defiant Disorder, ADHD
Interventions
Anger control training
Behavioral
Lead sponsor
Yale University
Other
Eligibility
11 Years to 16 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2006
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 11, 2022 · Synced Oct 20, 2026, 10:45 AM EDT
Recruiting Not applicable Interventional

Digital Dyadic Family Based Intervention to Improve Sleep in Children with ODD and Their Parents: NiteCAPP SINCC (Pilot)

NCT06410495
View directory record Official record
Conditions
Oppositional Defiant Disorder, Insomnia Chronic
Interventions
NiteCAPP SINCC
Behavioral
Lead sponsor
University of South Florida
Other
Eligibility
8 Years to 17 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
Tampa, Florida
Source: ClinicalTrials.gov public record
Updated Mar 28, 2025 · Synced Oct 20, 2026, 10:45 AM EDT
Completed Phase 1 Interventional

Trial to Assess the Pharmacokinetics, Safety, Tolerability of Oral Brexpiprazole in Children (6 to <13 Years Old) With Central Nervous System Disorders

NCT03292848
View directory record Official record
Conditions
ADHD, Autism, Bipolar I Disorder, Conduct Disorder, Oppositional Defiant Disorder
Interventions
Brexpiprazole
Drug
Lead sponsor
Otsuka Pharmaceutical Development & Commercialization, Inc.
Industry
Eligibility
6 Years to 12 Years
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
9
States / cities
Little Rock, Arkansas • Rogers, Arkansas • Long Beach, California + 4 more
Source: ClinicalTrials.gov public record
Updated Jun 12, 2018 · Synced Oct 20, 2026, 10:45 AM EDT
Active, not recruiting Not applicable Interventional

Digital Therapeutics for Behavior Problems

NCT05647772
View directory record Official record
Conditions
Problem Behavior, Child Behavior
Interventions
UseIt! App, Coach, SmilingMind App
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
5 Years to 8 Years
Enrollment
324 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
1
States / cities
Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jul 10, 2026 · Synced Oct 20, 2026, 10:45 AM EDT
Completed Phase 4 Interventional Results available

Metabolic Effects of Antipsychotics in Children

NCT00205699
View directory record Official record
Conditions
Aggression, Attention Deficit-Hyperactivity, Oppositional Defiant Disorder, Pervasive Development Disorders, Bipolar Disorder
Interventions
risperidone, olanzapine, aripiprazole
Drug
Lead sponsor
Washington University School of Medicine
Other
Eligibility
6 Years to 18 Years
Enrollment
144 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
1
States / cities
St Louis, Missouri
Source: ClinicalTrials.gov public record
Updated Jun 15, 2018 · Synced Oct 20, 2026, 10:45 AM EDT
Not listed Phase 4 Interventional

Effectiveness of Combined Medication Treatment for Aggression in Children With Attention Deficit With Hyperactivity Disorder (The SPICY Study)

NCT00794625
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity
Interventions
Valproate, Risperidone, Placebo, Stimulant medication, Behavioral family counseling
Drug · Behavioral
Lead sponsor
Joseph Blader
NIH
Eligibility
6 Years to 12 Years
Enrollment
270 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2013
U.S. locations
3
States / cities
Glen Oaks, New York • Stony Brook, New York • San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated Jul 16, 2012 · Synced Oct 20, 2026, 10:45 AM EDT
Completed Phase 4 Interventional Results available

Intuniv vs Placebo in the Treatment of Childhood Intermittent Explosive Disorder

NCT02048241
View directory record Official record
Conditions
Intermittent Explosive Disorder, Childhood Aggression, Oppositional Defiant Disorder, Attention Deficit Disorder
Interventions
Parent Management Training, Placebo, Intuniv
Behavioral · Other · Drug
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
6 Years to 12 Years
Enrollment
11 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2014
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 13, 2018 · Synced Oct 20, 2026, 10:45 AM EDT
Completed Phase 4 Interventional

Medication Strategies for Treating Aggressive Behavior in Youth With Attention Deficit Hyperactivity Disorder

NCT00228046
View directory record Official record
Conditions
Attention Deficit Disorder With Hyperactivity, Conduct Disorder, Oppositional Defiant Disorder
Interventions
Divalproex Sodium, Methylphenidate, Dextroamphetamine, Mixed Amphetamine Salts, Family Counseling, Behavior Management Training with Parents
Drug · Behavioral
Lead sponsor
Stony Brook University
Other
Eligibility
6 Years to 14 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2007
U.S. locations
2
States / cities
New Hyde Park, New York • Stony Brook, New York
Source: ClinicalTrials.gov public record
Updated Oct 31, 2013 · Synced Oct 20, 2026, 10:45 AM EDT
Recruiting Not applicable Interventional

SKIP for PA Study: Team and Leadership Level Implementation Support for Collaborative Care

NCT04946253
View directory record Official record
Conditions
Child Behavior Problem, Attention Deficit and Disruptive Behavior Disorders
Interventions
DOCC: Evidence-based treatment for disruptive behavior and ADHD, TEAM: Implementation support strategies at the care team level following standard implementation of DOCC, Implementation support strategies at the leadership level following standard implementation of DOCC
Behavioral
Lead sponsor
University of Pittsburgh
Other
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
2
States / cities
Philadelphia, Pennsylvania • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 9, 2026 · Synced Oct 20, 2026, 10:45 AM EDT
Withdrawn Not applicable Interventional

Mobile Health Solutions for Behavioral Skill Implementation Through Homework

NCT02662140
View directory record Official record
Conditions
Oppositional Defiant, Conduct Disorder
Interventions
Mobile Health Applictaion
Behavioral
Lead sponsor
NYU Langone Health
Other
Eligibility
7 Years to 11 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Dec 29, 2016 · Synced Oct 20, 2026, 10:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Monitoring of Sleep and Behavior of Children 3-7 Years Old Receiving Parent-Child Interaction Therapy With the Help of Artificial Intelligence

NCT05077722
View directory record Official record
Conditions
Disruptive Behavior, Attention-deficit Hyperactivity, Oppositional Defiant Disorder
Interventions
Garmin
Device
Lead sponsor
Mayo Clinic
Other
Eligibility
3 Years to 99 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2023
U.S. locations
1
States / cities
Rochester, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 22, 2024 · Synced Oct 20, 2026, 10:45 AM EDT
Completed Not applicable Interventional Results available

School-Based Mental Health Services for Urban Children

NCT00612690
View directory record Official record
Conditions
Conduct Disorder, Oppositional Defiant Disorder, Attention Deficit Disorder With Hyperactivity
Interventions
Community mental health consultation model program, Treatment as usual (TAU)
Behavioral
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
5 Years to 12 Years
Enrollment
482 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2010
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 4, 2014 · Synced Oct 20, 2026, 10:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Multi-Family Group Therapy for Reducing Behavioral Difficulties in Youth

NCT00404911
View directory record Official record
Conditions
Oppositional Defiant Disorder, Conduct Disorder
Interventions
MFG therapy, Standard of Care
Behavioral
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
7 Years and older
Enrollment
416 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2006 – 2013
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 25, 2013 · Synced Oct 20, 2026, 10:45 AM EDT
Not listed Phase 1 Interventional

Treatment of Conduct Problems and Depression

NCT01267773
View directory record Official record
Conditions
Depression, Oppositional Defiant Disorder, Conduct Disorder
Interventions
Integrated Treatment
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
8 Years to 14 Years
Enrollment
30 participants
Timeline
2010 – 2013
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 21, 2013 · Synced Oct 20, 2026, 10:45 AM EDT
Completed Not applicable Interventional Results available

Behavioral Treatment for Children With Conduct Problems and Callous-Unemotional Traits

NCT01362946
View directory record Official record
Conditions
Conduct Disorder, Oppositional Defiant Disorder
Interventions
Reward-Emphasized Treatment, Standard Treatment
Behavioral
Lead sponsor
Florida International University
Other
Eligibility
7 Years to 12 Years
Enrollment
48 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012
U.S. locations
1
States / cities
Miami, Florida
Source: ClinicalTrials.gov public record
Updated Jan 15, 2016 · Synced Oct 20, 2026, 10:45 AM EDT
Completed Not applicable Interventional

On-line Treatment for Conduct Problems

NCT01822392
View directory record Official record
Conditions
Conduct Disorder, Oppositional Defiant Disorder
Interventions
Online Parent Management Training (Interactive), Online Parent Management Training (Recorded)
Behavioral
Lead sponsor
Yale University
Other
Eligibility
6 Years to 12 Years
Enrollment
86 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Feb 23, 2026 · Synced Oct 20, 2026, 10:45 AM EDT
Completed Not applicable Interventional

Evaluation of Regulation Focused Psychotherapy for Children

NCT03594253
View directory record Official record
Conditions
Oppositional Defiant Disorder, Oppositional Defiant Disorder in Children
Interventions
Regulation Focused Psychotherapy for Children
Behavioral
Lead sponsor
Yeshiva University
Other
Eligibility
5 Years to 12 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2020
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Jan 30, 2023 · Synced Oct 20, 2026, 10:45 AM EDT
Completed Phase 3 Interventional

Study to Determine Whether There Are Any Cognitive or Motor Effects From Taking the Medicine Risperidone.

NCT00399698
View directory record Official record
Conditions
Oppositional Defiant Disorder, Conduct Disorder, Attention Deficit/Hyperactivity Disorder (ADHD), Intermittent Explosive Disorder, Impulse-Control Disorders, Adjustment Disorder, Bipolar Disorder, Pervasive Developmental Disorder
Interventions
Risperdal
Drug
Lead sponsor
Ohio State University
Other
Eligibility
4 Years to 14 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2005
U.S. locations
1
States / cities
Columbus, Ohio
Source: ClinicalTrials.gov public record
Updated Jun 23, 2016 · Synced Oct 20, 2026, 10:45 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Resources to Enhance the Adjustment of Children (REACH)

NCT00820001
View directory record Official record
Conditions
Oppositional Defiant Disorder, Conduct Disorder, Attention Deficit Hyperactivity Disorder
Interventions
Booster Treatment, No-Booster, No intervention, Treatment As Usual
Behavioral · Other
Lead sponsor
University of Pittsburgh
Other
Eligibility
6 Years to 11 Years
Enrollment
254 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2003 – 2009
U.S. locations
2
States / cities
Cincinnati, Ohio • Pittsburgh, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Feb 18, 2013 · Synced Oct 20, 2026, 10:45 AM EDT
Completed Not applicable Interventional

Evaluating an Online Parenting Support System Disseminated by Pediatric Practices

NCT02064452
View directory record Official record
Conditions
Child Disruptive Behavior Disorders, Oppositional Defiant Disorder, Conduct Disorder, Attention Deficit Hyperactivity Disorder
Interventions
Triple P Online System, Placebo Comparator
Other · Behavioral
Lead sponsor
Oregon Research Institute
Other
Eligibility
3 Years and older
Enrollment
600 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2019
U.S. locations
2
States / cities
Eugene, Oregon • Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Apr 18, 2019 · Synced Oct 20, 2026, 10:45 AM EDT