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Showing 1–24 of 254 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Defibrillator Clear all
Recruiting Not applicable Interventional

Safety and Performance Assessment of the Sphere-9™ Catheter and Affera™ Ablation System for the Treatment of Ventricular Tachycardia (Sphere-9 VT EFS)

NCT06703489
View directory record Official record
Conditions
Ventricular Tachycardia (VT)
Interventions
Sphere-9 Catheter with the Affera Mapping and Ablation System
Device
Lead sponsor
Medtronic Cardiac Ablation Solutions
Industry
Eligibility
18 Years to 85 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
6
States / cities
Boston, Massachusetts • New York, New York • Cleveland, Ohio + 3 more
Source: ClinicalTrials.gov public record
Updated Jun 15, 2026 · Synced Sep 2, 2026, 6:22 AM EDT
Completed Phase 1 Interventional

Cardiac Autonomic Regulation Enhancement Through Exercise Trial

NCT00845091
View directory record Official record
Conditions
Cardiovascular Disease, Arrhythmias
Interventions
Exercise, Heart Healthy Education
Behavioral
Lead sponsor
The Miriam Hospital
Other
Eligibility
18 Years and older
Enrollment
22 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Jan 7, 2014 · Synced Sep 2, 2026, 6:22 AM EDT
Completed Not applicable Interventional

Cardiac Resynchronization Therapy Defibrillator Based Impedance Monitoring Study

NCT00500838
View directory record Official record
Conditions
Heart Failure
Interventions
Transthoracic Impedance
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2008
U.S. locations
4
States / cities
Little Rock, Arkansas • Glendale, California • Browns Mills, New Jersey + 1 more
Source: ClinicalTrials.gov public record
Updated Jan 31, 2019 · Synced Sep 2, 2026, 6:22 AM EDT
Completed No phase listed Observational Results available

Heart Failure Optimization Study

NCT03016754
View directory record Official record
Conditions
Sudden Cardiac Death, Sudden Cardiac Arrest, Heart Failure, Heart Failure Low Output
Interventions
Wearable Cardioverter Defibrillator
Device
Lead sponsor
Zoll Medical Corporation
Industry
Eligibility
18 Years and older
Enrollment
602 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
39
States / cities
Birmingham, Alabama • West Hills, California • Fernandina Beach, Florida + 34 more
Source: ClinicalTrials.gov public record
Updated Mar 23, 2025 · Synced Sep 2, 2026, 6:22 AM EDT
Completed No phase listed Observational

Patient and Physician Survey Determinants of Appropriate ICD Utilization

NCT01514773
View directory record Official record
Conditions
Heart Failure, Systolic
Interventions
Not listed
Lead sponsor
Todd M Koelling, MD
Other
Eligibility
18 Years and older
Enrollment
452 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Mar 16, 2017 · Synced Sep 2, 2026, 6:22 AM EDT
Completed Not applicable Interventional

A Pilot Trial of Patient Decision Aids for Implantable Cardioverter-Defibrillators (ICDs)

NCT02026102
View directory record Official record
Conditions
Systolic Heart Failure, Sudden Cardiac Death
Interventions
ICD Decision Aid Toolkit
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
3
States / cities
Aurora, Colorado • Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Oct 30, 2019 · Synced Sep 2, 2026, 6:22 AM EDT
Completed Phase 1 Interventional

Nurses Helping Sudden Cardiac Arrest Survivors Recover After Getting An Implantable Cardioverter Defibrillator (ICD)

NCT00226681
View directory record Official record
Conditions
Sudden Cardiac Arrest
Interventions
Nursing Telephone Support Protocol, Usual Care
Behavioral
Lead sponsor
National Institute of Nursing Research (NINR)
NIH
Eligibility
12 Years to 90 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
1999 – 2004
U.S. locations
1
States / cities
Seattle, Washington
Source: ClinicalTrials.gov public record
Updated Sep 9, 2008 · Synced Sep 2, 2026, 6:22 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

University Hospital Cardiac Device MR Registry: The Safety of MR Imaging in Patients With Implanted Cardiac Devices

NCT02548819
View directory record Official record
Conditions
MRI, Pacemaker, Defibrillator
Interventions
MRI
Other
Lead sponsor
University Health Care System, Augusta, Georgia
Other
Eligibility
18 Years and older
Enrollment
220 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2017
U.S. locations
1
States / cities
Augusta, Georgia
Source: ClinicalTrials.gov public record
Updated May 31, 2017 · Synced Sep 2, 2026, 6:22 AM EDT
Completed Not applicable Interventional Results available

ENABLE MRI (Magnetic Resonance Imaging)

NCT02652481
View directory record Official record
Conditions
Magnetic Resonance Imaging
Interventions
ImageReady MR Conditional Defibrillation System
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
18 Years and older
Enrollment
500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2018
U.S. locations
34
States / cities
Huntsville, Alabama • Jonesboro, Arkansas • Pasadena, California + 31 more
Source: ClinicalTrials.gov public record
Updated Jan 24, 2021 · Synced Sep 2, 2026, 6:22 AM EDT
Completed Not applicable Interventional Results available

Heart Rate Response to Regadenoson and Sudden Cardiac Death

NCT01842035
View directory record Official record
Conditions
Left Ventricular Systolic Dysfunction, Sudden Cardiac Death
Interventions
regadenoson
Drug
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
19 Years to 80 Years
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2022
U.S. locations
1
States / cities
Birmingham, Alabama
Source: ClinicalTrials.gov public record
Updated Oct 17, 2022 · Synced Sep 2, 2026, 6:22 AM EDT
Completed No phase listed Observational

Heart Sounds Registry

NCT03203629
View directory record Official record
Conditions
Heart Failure; With Decompensation
Interventions
Wearable Cardioverter Defibrillator (WCD)
Device
Lead sponsor
Zoll Medical Corporation
Industry
Eligibility
18 Years and older
Enrollment
705 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
17
States / cities
National City, California • Atlantis, Florida • Fort Lauderdale, Florida + 14 more
Source: ClinicalTrials.gov public record
Updated Apr 22, 2021 · Synced Sep 2, 2026, 6:22 AM EDT
Completed Phase 4 Interventional Results available

OptiVol® Care Pathway

NCT00847288
View directory record Official record
Conditions
Heart Failure
Interventions
Monthly Review Arm, Quarterly Review Arm
Other
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
1,682 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2011
U.S. locations
108
States / cities
Birmingham, Alabama • Mobile, Alabama • Anchorage, Alaska + 105 more
Source: ClinicalTrials.gov public record
Updated May 2, 2013 · Synced Sep 2, 2026, 6:22 AM EDT
Completed Not applicable Interventional Results available

Multicenter Automatic Defibrillator Implantation Trial - Reduce Inappropriate Therapy

NCT00947310
View directory record Official record
Conditions
Primary Prevention of Sudden Cardiac Arrest
Interventions
Standard ICD programming, High rate cutoff, Long delay
Device
Lead sponsor
Boston Scientific Corporation
Industry
Eligibility
21 Years and older
Enrollment
1,500 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2012
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Aug 7, 2018 · Synced Sep 2, 2026, 6:22 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Electronic Patient Notification of Remote ICD Data: Impact of Patient Engagement on Outcomes in the Merlin.Net™

NCT02989090
View directory record Official record
Conditions
Implantable Cardioverter-Defibrillator, Health Information Exchange, Electronic Health Records, Patient Participation
Interventions
Receive Detailed ICD Information-electronic, Receive Detailed ICD Information-paper
Other
Lead sponsor
Parkview Hospital, Indiana
Other
Eligibility
18 Years and older
Enrollment
191 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
1
States / cities
Fort Wayne, Indiana
Source: ClinicalTrials.gov public record
Updated Aug 29, 2019 · Synced Sep 2, 2026, 6:22 AM EDT
Completed No phase listed Observational

Study Evaluating the Use of MRI on CMS Patients

NCT02513056
View directory record Official record
Conditions
Pacemaker, Implantable Cardioverter Defibrillators
Interventions
MRI
Other
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years and older
Enrollment
872 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2022
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 13, 2024 · Synced Sep 2, 2026, 6:22 AM EDT
Completed Not applicable Interventional Results available

Reducing Decompensation Events Utilizing Intracardiac Pressures in Patients With Chronic Heart Failure (HF) (REDUCEhf)

NCT00354159
View directory record Official record
Conditions
Heart Failure
Interventions
Implantable Hemodynamic Monitor (Chronicle® IHM), and IHM in combination with single chamber ICD (Chronicle ICD)
Device
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
442 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2011
U.S. locations
52
States / cities
Birmingham, Alabama • La Jolla, California • Loma Linda, California + 43 more
Source: ClinicalTrials.gov public record
Updated Aug 8, 2012 · Synced Sep 2, 2026, 6:22 AM EDT
Completed No phase listed Observational

Safety of Sports for Patients With Implantable Cardioverter-Defibrillators

NCT00637754
View directory record Official record
Conditions
Heart Arrhythmias
Interventions
Not listed
Lead sponsor
Yale University
Other
Eligibility
10 Years to 60 Years
Enrollment
400 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2015
U.S. locations
31
States / cities
Phoenix, Arizona • Tucson, Arizona • Little Rock, Arkansas + 23 more
Source: ClinicalTrials.gov public record
Updated Jun 10, 2015 · Synced Sep 2, 2026, 6:22 AM EDT
Completed No phase listed Observational Results available

SJ4 Post Approval Study in Implantable Cardioverter-Defibrillator and Cardiac Resynchronization Therapy Defibrillator Patients

NCT00940888
View directory record Official record
Conditions
Tachyarrhythmias, Sudden Cardiac Death, Heart Failure
Interventions
SJ4 connector and RV high voltage SJ4 lead
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
1,701 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009 – 2015
U.S. locations
1
States / cities
Cleveland, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 3, 2019 · Synced Sep 2, 2026, 6:22 AM EDT
Completed No phase listed Observational

PROSPECT: Predictors of Response to Cardiac Re-Synchronization Therapy

NCT00253357
View directory record Official record
Conditions
Heart Failure, Congestive Heart Failure, Cardiomyopathy
Interventions
Not listed
Lead sponsor
Medtronic Cardiac Rhythm and Heart Failure
Industry
Eligibility
18 Years and older
Enrollment
450 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2004 – 2006
U.S. locations
16
States / cities
Several Locations, California • Gainsville, Florida • Atlanta, Georgia + 13 more
Source: ClinicalTrials.gov public record
Updated Dec 20, 2007 · Synced Sep 2, 2026, 6:22 AM EDT
Completed No phase listed Observational

Study of the Wearable Defibrillator in Heart-Failure Patients

NCT01326624
View directory record Official record
Conditions
Heart Failure, Ventricular Dysfunction, Sudden Death, Sudden Cardiac Arrest, Ventricular Tachycardia, Ventricular Fibrillation
Interventions
wearable defibrillator (LifeVest)
Device
Lead sponsor
Zoll Medical Corporation
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2017
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Dec 5, 2017 · Synced Sep 2, 2026, 6:22 AM EDT
Recruiting No phase listed Observational

Implantable Cardioverter Defibrillator (ICD Registry)

NCT01999140
View directory record Official record
Conditions
Heart Failure, Nonischemic Cardiomyopathy, Ischemic Cardiomyopathy, Ventricular Arrhythmia, Complications; Device, Cardiac
Interventions
Not listed
Lead sponsor
American College of Cardiology
Other
Eligibility
Not listed
Enrollment
1,750 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2030
U.S. locations
1
States / cities
Washington D.C., District of Columbia
Source: ClinicalTrials.gov public record
Updated Apr 17, 2024 · Synced Sep 2, 2026, 6:22 AM EDT
Terminated Phase 3 Interventional

Efficacy and Safety Study of Azimilide on the Incidence of Cardiovascular Hospitalizations/Emergency Department Visits or Cardiovascular Death in Patients With an Implantable Cardioverter Defibrillator (ICD) (SHIELD-2)

NCT01464476
View directory record Official record
Conditions
Arrhythmias, Cardiac, Heart Diseases, Cardiovascular Diseases, Implantable Cardioverter Defibrillator
Interventions
Azimilide Dihydrochloride, Placebo
Drug
Lead sponsor
Forest Laboratories
Industry
Eligibility
18 Years and older
Enrollment
240 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2013
U.S. locations
83
States / cities
Birmingham, Alabama • Huntsville, Alabama • Phoenix, Arizona + 72 more
Source: ClinicalTrials.gov public record
Updated May 5, 2013 · Synced Sep 2, 2026, 6:22 AM EDT
Completed Phase 4 Interventional

Reduce Ventricular Pacing in Dual Chamber Implantable Cardioverter Defibrillators Using AutoIntrinsic Conduction Search Study

NCT00187239
View directory record Official record
Conditions
Arrhythmia
Interventions
Autointrinsic Conduction Search Algorithm
Device
Lead sponsor
Abbott Medical Devices
Industry
Eligibility
18 Years and older
Enrollment
157 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2007
U.S. locations
1
States / cities
Pomona, New Jersey
Source: ClinicalTrials.gov public record
Updated Feb 3, 2019 · Synced Sep 2, 2026, 6:22 AM EDT
Completed Not applicable Interventional Results available

Educational Videos to Address Racial Disparities in Implantable Cardioverter Defibrillator Therapy

NCT02819973
View directory record Official record
Conditions
Sudden Cardiac Death, Heart Failure
Interventions
Educational Video1, Educational Video 2, Usual Care 3
Other
Lead sponsor
Duke University
Other
Eligibility
21 Years and older
Enrollment
343 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2020
U.S. locations
14
States / cities
San Francisco, California • Washington D.C., District of Columbia • Atlanta, Georgia + 11 more
Source: ClinicalTrials.gov public record
Updated Apr 20, 2021 · Synced Sep 2, 2026, 6:22 AM EDT