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Conditions: Degenerative Disc Disease
Interventions: Lumbar I/F with cage and pedicle screws; Device
Lead sponsor: DePuy Spine; Industry
Eligibility: 18 Years to 79 Years
Enrollment: 139 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2006
U.S. locations: 2
States / cities: Dothan, Alabama • Fort Wayne, Indiana

Conditions: Degenerative Disc Disease, Craniocervical Injuries, Cervical Radiculopathy, Cervical Disc Disease, Cervical Fusion, Cervical Spine Disease, Cervical Myelopathy, Cervical Instabilities Spine, Thoracic Injury
Interventions: observational study; Device
Lead sponsor: NuVasive; Industry
Eligibility: 18 Years and older
Enrollment: 150 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2022 – 2028
U.S. locations: 7
States / cities: Orange, California • Hartford, Connecticut • Hyattsville, Maryland + 4 more

Conditions: Lumbar Degenerative Disc Disease
Interventions: SIFS graft containment device; Device
Lead sponsor: Spineology, Inc; Industry
Eligibility: 21 Years to 80 Years
Enrollment: 102 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2015 – 2020
U.S. locations: 10
States / cities: DeLand, Florida • Shreveport, Louisiana • Thibodaux, Louisiana + 7 more

Conditions: Degenerative Disc Disease
Interventions: Autologous Adipose-Derived Mesenchymal Stromal Cells; Drug
Lead sponsor: Mayo Clinic; Other
Eligibility: 18 Years and older
Enrollment: 1 participant
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2018 – 2021
U.S. locations: 1
States / cities: Rochester, Minnesota

Conditions: Degenerative Disc Disease
Interventions: Aspen Spinous Process System, Pedicle Screw Fixation; Device
Lead sponsor: Zimmer Biomet; Industry
Eligibility: 18 Years to 75 Years
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2009 – 2016
U.S. locations: 5
States / cities: Pomona, California • Sacramento, California • Kansas City, Kansas + 2 more

Conditions: Degenerative Disc Disease
Interventions: IDCT (rebonuputemcel), Sham (No Treatment); Biological · Other
Lead sponsor: DiscGenics, Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 162 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2025 – 2028
U.S. locations: 14
States / cities: Birmingham, Alabama • Santa Monica, California • St. Petersburg, Florida + 11 more

Conditions: Chronic Low-back Pain, Degenerative Disc Disease
Interventions: CELZ-201-DDT, Placebo; Drug · Other
Lead sponsor: Creative Medical Technology Holdings Inc; Industry
Eligibility: 18 Years to 80 Years
Enrollment: 45 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2024 – 2027
U.S. locations: 1
States / cities: Aventura, Florida

Conditions: Vertebral Cervical Fusion Syndrome, Degenerative Disc Disease
Interventions: CervicalStim bone growth stimulator; Device
Lead sponsor: Orthofix Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 211 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2021
U.S. locations: 1
States / cities: Johnstown, Colorado

Conditions: Degenerative Disc Disease
Interventions: Not listed
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: Not listed
Enrollment: 200 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2012 – 2023
U.S. locations: 1
States / cities: New York, New York

Conditions: Lumbar Degenerative Disc Disease
Interventions: PureGen Osteoprogenitor Cell Allograft; Biological
Lead sponsor: Alphatec Spine, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: Started 2011
U.S. locations: 3
States / cities: Beverly Hills, California • Middleton, Connecticut • Greensboro, North Carolina

Conditions: Spondylolisthesis, Spinal Stenosis, Low Back Pain
Interventions: Decompressive laminectomy, Non-surgical treatments, Fusion--Instrumented, Fusion-Non-instrumented; Procedure · Other
Lead sponsor: Dartmouth-Hitchcock Medical Center; Other
Eligibility: 18 Years and older
Enrollment: 304 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2000 – 2015
U.S. locations: 13
States / cities: Oakland, California • San Francisco, California • Decatur, Georgia + 9 more

Conditions: Scoliosis; Adolescence, Degenerative Disc Disease, Spinal Fusion, Kyphoscoliosis, Pseudoarthrosis of Spine, Spinal Stenosis, Kyphoses, Scheuermann
Interventions: Patient Specific Rod; Device
Lead sponsor: University of Colorado, Denver; Other
Eligibility: 10 Years to 85 Years
Enrollment: 1,000 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2020 – 2030
U.S. locations: 1
States / cities: Aurora, Colorado

Conditions: Degenerative Disc Disease, DDD, Degenerative Disc Disease Lumbar, Degenerative Disc Disease, Lumbar, Lumbar Disc Herniation, Disc Herniation, Lumbar, Bone Marrow Aspirate Concentrate, Intervertebral Disc Displacement, Low Back Pain, Chronic Low Back Pain (CLBP), CLBP - Chronic Low Back Pain
Interventions: Bone Marrow Aspirate Concentrate (BMAC); Other
Lead sponsor: Weill Medical College of Cornell University; Other
Eligibility: 18 Years and older
Enrollment: 90 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2030
U.S. locations: 1
States / cities: Manhattan, New York

Conditions: Low Back Pain
Interventions: Biostat® Disc Augmentation System; Biological
Lead sponsor: Spinal Restoration, Inc.; Industry
Eligibility: 18 Years to 75 Years
Enrollment: 15 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2008 – 2011
U.S. locations: 3
States / cities: Bethesda, Maryland • Tyler, Texas • Bellingham, Washington

Conditions: Intervertebral Disk Degeneration
Interventions: P-15 Synthetic osteoconductive bone substitute, Autologous bone; Device · Other
Lead sponsor: CeraPedics, Inc; Industry
Eligibility: 18 Years to 70 Years
Enrollment: 319 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2006 – 2019
U.S. locations: 10
States / cities: San Francisco, California • Thornton, Colorado • Sarasota, Florida + 6 more

Conditions: Degenerative Disc Disease
Interventions: Medtronic Infinity Occipitocervical-Upper Thoracic System using the O-arm Imaging System and StealthStation Navigation system; Device
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 54 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Degenerative Lumbar Spondylolisthesis
Interventions: Spinal fusion; Procedure
Lead sponsor: Olympus Biotech Corporation; Industry
Eligibility: 18 Years to 85 Years
Enrollment: 336 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2001 – 2005
U.S. locations: 21
States / cities: Santa Monica, California • Stanford, California • Denver, Colorado + 18 more

Conditions: Degenerative Disc Disease
Interventions: Novosis Putty, Standard of Care; Device · Other
Lead sponsor: CGBio Inc.; Industry
Eligibility: 21 Years to 80 Years
Enrollment: 316 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2026 – 2031
U.S. locations: 5
States / cities: Baton Rouge, Louisiana • Shreveport, Louisiana • Philadelphia, Pennsylvania + 2 more

Conditions: Spinal Canal Stenosis, Spondylolisthesis, Osteophyte, Bony Growth Formation, Degenerative Disc Disease
Interventions: Medtronic Adaptix™ titanium implants, Medtronic CAPSTONE® PEEK cage; Device
Lead sponsor: Ohio State University; Other
Eligibility: 18 Years and older
Enrollment: 100 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2021 – 2026
U.S. locations: 1
States / cities: Columbus, Ohio

Conditions: Degenerative Disc Disease
Interventions: Lumbar Artificial Disc, Charite Artificial Disc; Device
Lead sponsor: SpinalMotion; Industry
Eligibility: 18 Years to 60 Years
Enrollment: 514 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2005 – 2013
U.S. locations: 21
States / cities: Beverly Hills, California • Encinitas, California • Oakland, California + 18 more

Conditions: Degenerative Disc Disease, Spine Degeneration
Interventions: Autologous Bone Marrow Aspirate Concentrate (BMAC) Injection; Other
Lead sponsor: Bone and Joint Clinic of Baton Rouge; Other
Eligibility: 18 Years to 60 Years
Enrollment: 20 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2019 – 2022
U.S. locations: 1
States / cities: Baton Rouge, Louisiana

Conditions: Pseudoarthrosis, Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease (DDD)
Interventions: Not listed
Lead sponsor: Baxano Surgical, Inc.; Industry
Eligibility: 18 Years and older
Enrollment: 60 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2013 – 2014
U.S. locations: 5
States / cities: Tampa, Florida • Indianapolis, Indiana • Baton Rouge, Louisiana + 2 more

Conditions: Lumbar Spondylolisthesis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Lumbar Radiculopathy, Lumbar Spinal Stenosis, Lumbar Disc Disease
Interventions: ViviGen® Cellular Bone Matrix with DePuy Synthes Spinal Pedicle screw system, Local Bone Autologous Bone Graft with DePuy Synthes Spinal pedicle screw system; Combination Product
Lead sponsor: Corewell Health East; Other
Eligibility: 18 Years and older
Enrollment: 46 participants
Healthy volunteers: Accepts healthy volunteers
Timeline: 2019 – 2024
U.S. locations: 1
States / cities: Royal Oak, Michigan

Conditions: Degenerative Disc Disease
Interventions: SM04690; Drug
Lead sponsor: Biosplice Therapeutics, Inc.; Industry
Eligibility: 25 Years to 55 Years
Enrollment: 6 participants
Healthy volunteers: Healthy volunteers not accepted
Timeline: 2017 – 2018
U.S. locations: 4
States / cities: San Diego, California • Charleston, South Carolina • Tyler, Texas + 1 more

Search by objective public record fields.

Titanium Surgical Mesh and MOSS-Miami Screws for Lumbar Fusion.

Posterior Cervical Fixation Study

Spineology Clinical Outcomes Trial: An IDE Investigation

Autologous, Culture-Expanded Mesenchymal Stromal Cells for Degenerative Disc Disease

Efficacy of the Aspen Spinous Process System in Anterior Lumbar Interbody Fusion (ALIF)

A Study to Evaluate the Effectiveness of IDCT (Intradiscal Cell Therapy) in Subjects With One Level, Symptomatic Mild to Moderate Lumbar Degenerative Disc Disease

Safety, Tolerability, and Effectiveness of Intramuscular Injection of CELZ-201-DDT for the Treatment of Chronic Lower Back Pain

Study Using the CervicalStim Device Following Cervical Fusion

Outcome Analysis for Minimally Invasive Spine Surgery and Navigation

Radiographic and Clinical Outcomes of PureGen in Posterior Lumbar (PLIF) and Transforaminal Interbody Fusion (TLIF)

Spine Patient Outcomes Research Trial (SPORT): Degenerative Spondylolisthesis With Spinal Stenosis

Personalized Spine Study Group (PSSG) Registry

Biologic Injection For Adults With Lumbar Disc Herniation

Treatment of Symptomatic Lumbar Internal Disc Disruption (IDD) With the Biostat® Disc Augmentation System: A Pilot Study

An Assessment of P-15 Bone Putty in Anterior Cervical Fusion With Instrumentation

Clinical and Radiological Outcomes of Posterior Cervical Fusion with Medtronic Infinity Occipitocervical-Upper Thoracic (OCT) System

OP-1 Putty for Posterolateral Fusions

Efficacy and Safety of Novosis Putty in Transforaminal Lumbar Interbody Fusion for Patients With Lumbar Degenerative Disc Disease

Adaptix RCT Evaluating Adaptix™ Versus PEEK Cages

Kineflex Artificial Disc System to Treat Degenerative Disc Disease (DDD)

A Prospective Study of Clinical Outcomes Following a Single Intradiscal Injection of Bone Marrow Aspirate Concentrate (BMAC) for Single Level Discogenic Low Back Pain

A Study Comparing Fusion Rates of Two Lumbar Fusion Procedures

Clinical Outcomes Associated With the Use of ViviGen® for the Treatment of Lumbar Degenerative Disc Disease

A Study of the Safety, Tolerability, and Pharmacokinetics of SM04690 Injectable Suspension Following Single Intradiscal Injection in Subjects With Degenerative Disc Disease