- Conditions
- Intervertebral Disc Disease, Intervertebral Disc Degeneration, Spondylosis, Spondylolisthesis, Spinal Stenosis
- Interventions
- NuCel with Autograft
- Other
- Lead sponsor
- NuTech Medical, Inc
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 57 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2019
- U.S. locations
- 1
- States / cities
- Charlotte, North Carolina
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Showing 1–24
of 115
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Degenerative Disc Disease
- Interventions
- ILIF
- Procedure
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 40 Years and older
- Enrollment
- 77 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2014
- U.S. locations
- 8
- States / cities
- Phoenix, Arizona • Santa Monica, California • Gainesville, Florida + 5 more
- Conditions
- Radiculopathy, Herniated Disc, Disc Degeneration
- Interventions
- Regenexx PL-Disc, Steroid Epidural
- Procedure
- Lead sponsor
- Regenexx, LLC
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 1
- States / cities
- Broomfield, Colorado
- Conditions
- Degenerative Disc Disease
- Interventions
- XL TDR, Lumbar fusion surgery
- Device · Other
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 246 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2015
- U.S. locations
- 17
- States / cities
- Campbell, California • Thousand Oaks, California • Durango, Colorado + 14 more
- Conditions
- Degenerative Lumbar Spondylolisthesis
- Interventions
- Use of OP-1 Putty in Uninstrumented posterolateral fusion
- Device
- Lead sponsor
- Olympus Biotech Corporation
- Industry
- Eligibility
- 18 Years to 81 Years
- Enrollment
- 48 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 1999 – 2005
- U.S. locations
- 5
- States / cities
- New Haven, Connecticut • Chicago, Illinois • Royal Oak, Michigan + 2 more
- Conditions
- Spondylolisthesis, Lumbar Region, Spinal Trauma With Neurological Deficit, Degeneration of Lumbar Intervertebral Disc
- Interventions
- Use of Viper Prime/Expedium system with Fibergraft BG Putty
- Device
- Lead sponsor
- Nitin Agarwal
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2029
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Retrolisthesis
- Interventions
- Surgery with the Keos Lumbar Interbody Fusion Device
- Device
- Lead sponsor
- Invibio Ltd
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- Lancaster, Pennsylvania
- Conditions
- Degenerative Disc Disease
- Interventions
- One-level or two-level anterior lumbar interbody fusion, InQu Bone Graft Extender and Substitute mixed with BMAC, Synthes Spinal Instrumentation
- Procedure · Biological · Device
- Lead sponsor
- Kansas Joint and Spine Institute
- Network
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2015
- U.S. locations
- 2
- States / cities
- Wichita, Kansas
- Conditions
- Degenerative Disc Disease
- Interventions
- Natural Matrix Protein (NMP)
- Biological
- Lead sponsor
- Induce Biologics USA Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 53 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2023 – 2024
- U.S. locations
- 1
- States / cities
- Shreveport, Louisiana
- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Spondylolisthesis, Lumbar Spondylosis, Lumbar Radiculopathy, Lumbar Spine Instability, Synovial Cyst, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Intervertebral Discs
- Interventions
- Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine, normal saline
- Drug
- Lead sponsor
- John O'Toole
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 125 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Degenerative Disc Disease
- Interventions
- Osteocel Plus
- Biological
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Prolapsed Lumbar Disc, Prolapsed Cervical Disc, Intervertebral Disc Degeneration, Spondylolisthesis, Grade 1, Intervertebral Disc Displacement
- Interventions
- Not listed
- Lead sponsor
- Wenzel Spine
- Industry
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 69 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 3
- States / cities
- Boston, Massachusetts • San Antonio, Texas
- Conditions
- Lumbar Degenerative Disc Disease
- Interventions
- AlterG
- Other
- Lead sponsor
- Justin Parker Neurological Institute
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 27 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2016
- U.S. locations
- 1
- States / cities
- Boulder, Colorado
- Conditions
- Lumbar Degenerative Disc Disease, Lower Back Pain, Chronic Lower Back Pain
- Interventions
- Not listed
- Lead sponsor
- The Foundation for Spinal Research, Education and Humanitarian Care, Inc.
- Industry
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2018
- U.S. locations
- 1
- States / cities
- Odessa, Florida
- Conditions
- Degenerative Disc Disease
- Interventions
- Lumbar I/F with cage and pedicle screws
- Device
- Lead sponsor
- DePuy Spine
- Industry
- Eligibility
- 18 Years to 79 Years
- Enrollment
- 139 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2000 – 2006
- U.S. locations
- 2
- States / cities
- Dothan, Alabama • Fort Wayne, Indiana
- Conditions
- Degenerative Disc Disease
- Interventions
- Autologous Adipose-Derived Mesenchymal Stromal Cells
- Drug
- Lead sponsor
- Mayo Clinic
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 1 participant
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 1
- States / cities
- Rochester, Minnesota
- Conditions
- Degenerative Disc Disease
- Interventions
- Aspen Spinous Process System, Pedicle Screw Fixation
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years to 75 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2016
- U.S. locations
- 5
- States / cities
- Pomona, California • Sacramento, California • Kansas City, Kansas + 2 more
- Conditions
- Degenerative Disc Disease
- Interventions
- IDCT (rebonuputemcel), Sham (No Treatment)
- Biological · Other
- Lead sponsor
- DiscGenics, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 162 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 14
- States / cities
- Birmingham, Alabama • Santa Monica, California • St. Petersburg, Florida + 11 more
- Conditions
- Lumbar Degenerative Disc Disease
- Interventions
- PureGen Osteoprogenitor Cell Allograft
- Biological
- Lead sponsor
- Alphatec Spine, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- Started 2011
- U.S. locations
- 3
- States / cities
- Beverly Hills, California • Middleton, Connecticut • Greensboro, North Carolina
- Conditions
- Low Back Pain
- Interventions
- Biostat® Disc Augmentation System
- Biological
- Lead sponsor
- Spinal Restoration, Inc.
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 15 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2011
- U.S. locations
- 3
- States / cities
- Bethesda, Maryland • Tyler, Texas • Bellingham, Washington
- Conditions
- Degenerative Disc Disease
- Interventions
- Novosis Putty, Standard of Care
- Device · Other
- Lead sponsor
- CGBio Inc.
- Industry
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 316 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2031
- U.S. locations
- 5
- States / cities
- Baton Rouge, Louisiana • Shreveport, Louisiana • Philadelphia, Pennsylvania + 2 more
- Conditions
- Pseudoarthrosis, Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease (DDD)
- Interventions
- Not listed
- Lead sponsor
- Baxano Surgical, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 5
- States / cities
- Tampa, Florida • Indianapolis, Indiana • Baton Rouge, Louisiana + 2 more
- Conditions
- Lumbar Spondylolisthesis, Degenerative Disc Disease, Degenerative Spondylolisthesis, Lumbar Radiculopathy, Lumbar Spinal Stenosis, Lumbar Disc Disease
- Interventions
- ViviGen® Cellular Bone Matrix with DePuy Synthes Spinal Pedicle screw system, Local Bone Autologous Bone Graft with DePuy Synthes Spinal pedicle screw system
- Combination Product
- Lead sponsor
- Corewell Health East
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 46 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2024
- U.S. locations
- 1
- States / cities
- Royal Oak, Michigan
- Conditions
- Degenerative Disc Disease
- Interventions
- Tranexamic Acid, Saline Solution, Visual Acuity Exam, 3 Minute Diagnostic Interview for Confusion Assessment Method (3D-CAM)
- Drug · Diagnostic Test
- Lead sponsor
- Catherine R. Olinger
- Other
- Eligibility
- 18 Years to 90 Years
- Enrollment
- 123 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- Iowa City, Iowa