- Conditions
- Degenerative Disc Disease
- Interventions
- ProDisc™-L Total Disc Replacement (TDR)
- Device
- Lead sponsor
- Synthes USA HQ, Inc.
- Industry
- Eligibility
- 18 Years to 50 Years
- Enrollment
- 4 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2010 – 2011
- U.S. locations
- 1
- States / cities
- San Diego, California
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Showing 25–48
of 24
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Lumbar Degenerative Disc Disease, Lumbar Spinal Stenosis, Lumbar Spondylolisthesis, Lumbar Spinal Deformity, Lumbar Spondylosis
- Interventions
- Interbody cage (titanium), Interbody cage (PEEK)
- Device
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 53 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Radiculopathy, Herniated Disc, Disc Degeneration
- Interventions
- Regenexx PL-Disc, Steroid Epidural
- Procedure
- Lead sponsor
- Regenexx, LLC
- Industry
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 8 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2016
- U.S. locations
- 1
- States / cities
- Broomfield, Colorado
- Conditions
- Intervertebral Disc Disease, Intervertebral Disc Degeneration, Spondylosis, Spondylolisthesis, Spinal Stenosis
- Interventions
- NuCel with Autograft
- Other
- Lead sponsor
- NuTech Medical, Inc
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 57 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2019
- U.S. locations
- 1
- States / cities
- Charlotte, North Carolina
- Conditions
- Degenerative Disc Disease
- Interventions
- Intradiscal rhGDF-5
- Drug
- Lead sponsor
- DePuy Spine
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 32 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2013
- U.S. locations
- 8
- States / cities
- Santa Monica, California • Durango, Colorado • Marietta, Georgia + 5 more
- Conditions
- Degenerative Disc Disease, Disc Degeneration, Lumbar Discogenic Pain
- Interventions
- VIA Disc NP, Sham
- Other
- Lead sponsor
- VIVEX Biologics, Inc.
- Industry
- Eligibility
- 22 Years to 85 Years
- Enrollment
- 496 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 19
- States / cities
- Napa, California • Santa Monica, California • Thornton, Colorado + 16 more
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Spondylosis
- Interventions
- One or two level lumbar interbody fusion surgery, Nucel
- Procedure · Other
- Lead sponsor
- Organogenesis
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2022
- U.S. locations
- 3
- States / cities
- Tampa, Florida • Shreveport, Louisiana • Charlotte, North Carolina
- Conditions
- Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Degeneration, Spinal Stenosis
- Interventions
- Computed Tomography (CT) Scan of the Lumbar Spine
- Radiation
- Lead sponsor
- Bone and Joint Clinic of Baton Rouge
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 66 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2020
- U.S. locations
- 1
- States / cities
- Baton Rouge, Louisiana
- Conditions
- Degenerative Cervical Disc Disease, Degenerative Lumbar Diseases
- Interventions
- Anterior Cervical Interbody Fusion, Anterior lumbar Interbody Fusion, Lateral Lumbar Interbody Fusion
- Device
- Lead sponsor
- Silony Medical GmbH
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025
- U.S. locations
- 1
- States / cities
- San Ramon, California
- Conditions
- Low Back Pain, Herniation, Disc, Sciatic Radiculopathy, Intervertebral Disc Stenosis of Neural Canal, Intervertebral Disc Injury
- Interventions
- NSSD, Sham NSSD
- Device
- Lead sponsor
- University of South Florida
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 42 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2026
- U.S. locations
- 2
- States / cities
- Stanford, California • Tampa, Florida
- Conditions
- Degenerative Disc Disease, Lumbar
- Interventions
- Osteocel Plus
- Biological
- Lead sponsor
- NuVasive
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 51 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2012
- U.S. locations
- 7
- States / cities
- San Francisco, California • Indianapolis, Indiana • Kokomo, Indiana + 4 more
- Conditions
- Degenerative Disc Disease
- Interventions
- CHARITE
- Device
- Lead sponsor
- DePuy Spine
- Industry
- Eligibility
- Not listed
- Enrollment
- 367 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2007
- U.S. locations
- 10
- States / cities
- Los Angeles, California • Golden, Colorado • Chicago, Illinois + 7 more
- Conditions
- Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
- Interventions
- Natural Matrix Protein (NMP) Fibers, Lumbar interbody fusion, Cervical interbody fusion
- Biological · Procedure
- Lead sponsor
- Induce Biologics USA Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Jasper, Alabama
- Conditions
- Lumbar Degenerative Disc Disease
- Interventions
- SIFS graft containment device
- Device
- Lead sponsor
- Spineology, Inc
- Industry
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 102 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2020
- U.S. locations
- 10
- States / cities
- DeLand, Florida • Shreveport, Louisiana • Thibodaux, Louisiana + 7 more
- Conditions
- Degenerative Disc Disease, Spine Fusion, Back Pain
- Interventions
- MagnetOs Easypack Putty, Demineralized Bone Matrix or Fibers mixed with local autograft bone
- Device
- Lead sponsor
- Kuros Biosurgery AG
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 6
- States / cities
- Irvine, California • Grand Rapids, Michigan • St Louis, Missouri + 3 more
- Conditions
- Degenerative Disc Disease
- Interventions
- TLIF with a PEEK Spacer System and XIA Spinal System
- Device
- Lead sponsor
- Olympus Biotech Corporation
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2010
- U.S. locations
- 10
- States / cities
- Los Angeles, California • San Diego, California • Durango, Colorado + 7 more
- Conditions
- Sciatica, Lumbar Radiculopathy, Lower Back Pain, Degenerative Disc Disease, Chronic Low-back Pain (cLBP), Chronic Low Back and Leg Pain, Back Pain
- Interventions
- Active Cannabis, Placebo Cannabis
- Drug
- Lead sponsor
- University of California, San Diego
- Other
- Eligibility
- 21 Years to 65 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2027
- U.S. locations
- 1
- States / cities
- La Jolla, California
- Conditions
- Degenerative Disc Disease
- Interventions
- MagnetOs Flex Matrix
- Device
- Lead sponsor
- Research Source
- Network
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Southfield, Michigan
- Conditions
- Degenerative Disc Disease
- Interventions
- Aspen Spinous Process System, Pedicle Screw Fixation
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- 18 Years to 75 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2009 – 2016
- U.S. locations
- 5
- States / cities
- Pomona, California • Sacramento, California • Kansas City, Kansas + 2 more
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Retrolisthesis
- Interventions
- Surgery with the Keos Lumbar Interbody Fusion Device
- Device
- Lead sponsor
- Invibio Ltd
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2021 – 2026
- U.S. locations
- 1
- States / cities
- Lancaster, Pennsylvania
- Conditions
- Degenerative Disc Disease, Isthmic-lytic Spondylolisthesis, Degenerative Spondylolisthesis, Spinal Stenosis
- Interventions
- Solum IV, Bone Marrow Concentrate with general fluid concentrate (GFC) in Transforaminal Lumbar Interbody Fusion
- Combination Product
- Lead sponsor
- Seton Healthcare Family
- Other
- Eligibility
- 18 Years and older
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2017 – 2018
- U.S. locations
- 1
- States / cities
- Austin, Texas
- Conditions
- Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease (DDD)
- Interventions
- Not listed
- Lead sponsor
- Baxano Surgical, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2015
- U.S. locations
- 3
- States / cities
- Fullerton, California • Waterford, Michigan • Cleveland, Ohio
- Conditions
- Degenerative Disc Disease, DDD, Degenerative Disc Disease Lumbar, Degenerative Disc Disease, Lumbar, Lumbar Disc Herniation, Disc Herniation, Lumbar, Bone Marrow Aspirate Concentrate, Intervertebral Disc Displacement, Low Back Pain, Chronic Low Back Pain (CLBP), CLBP - Chronic Low Back Pain
- Interventions
- Bone Marrow Aspirate Concentrate (BMAC)
- Other
- Lead sponsor
- Weill Medical College of Cornell University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 90 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2026 – 2030
- U.S. locations
- 1
- States / cities
- Manhattan, New York
- Conditions
- Degenerative Disc Disease (DDD)
- Interventions
- The ReGelTec HYDRAFIL™ System, Conservative Care Management
- Device · Other
- Lead sponsor
- ReGelTec, Inc.
- Industry
- Eligibility
- 22 Years to 85 Years
- Enrollment
- 225 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2028
- U.S. locations
- 13
- States / cities
- Birmingham, Alabama • Santa Monica, California • Walnut Creek, California + 10 more