- Conditions
- Lumbar Spinal Stenosis, Lumbar Disc Herniation, Lumbar Spondylolisthesis, Lumbar Spondylosis, Lumbar Radiculopathy, Lumbar Spine Instability, Synovial Cyst, Degenerative Disc Disease, Degenerative Spondylolisthesis, Degenerative Intervertebral Discs
- Interventions
- Bupivacaine-Epinephrine 0.25%-1:200,000 Injectable Solution plus clonidine, normal saline
- Drug
- Lead sponsor
- John O'Toole
- Other
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 125 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2027
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
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Showing 1–24
of 73
matching trials from the live ClinicalTrials.gov search.
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- Conditions
- Lumbar Degenerative Disc Disease, Lumbar Spinal Stenosis, Lumbar Spondylolisthesis, Lumbar Spinal Deformity, Lumbar Spondylosis
- Interventions
- Interbody cage (titanium), Interbody cage (PEEK)
- Device
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 53 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2022
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Spondylosis, Cervical Spondylosis, Spondylolisthesis, Herniated Nucleus Pulposus, Degenerative Disc Disease
- Interventions
- ViBone
- Other
- Lead sponsor
- Elutia Inc.
- Industry
- Eligibility
- 18 Years to 80 Years
- Enrollment
- 118 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2018 – 2021
- U.S. locations
- 4
- States / cities
- San Diego, California • Danbury, Connecticut • Annapolis, Maryland + 1 more
- Conditions
- Lumbar Spine Disease, Lumbar Spondylolisthesis, Lumbar Spine Instability, Lumbar Spondylosis, Degenerative Disc Disease
- Interventions
- OSTEOAMP, Infuse
- Other · Device
- Lead sponsor
- Bioventus LLC
- Industry
- Eligibility
- 21 Years to 80 Years
- Enrollment
- 101 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2025
- U.S. locations
- 9
- States / cities
- New Haven, Connecticut • Wichita, Kansas • Paducah, Kentucky + 6 more
- Conditions
- Prolapsed Lumbar Disc, Prolapsed Cervical Disc, Intervertebral Disc Degeneration, Spondylolisthesis, Grade 1, Intervertebral Disc Displacement
- Interventions
- Not listed
- Lead sponsor
- Wenzel Spine
- Industry
- Eligibility
- 18 Years to 99 Years
- Enrollment
- 69 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2015
- U.S. locations
- 3
- States / cities
- Boston, Massachusetts • San Antonio, Texas
- Conditions
- Degenerative Disc Disease Lumbar, Spinal Stenosis, Lumbar Spondylolisthesis
- Interventions
- Multimodal Analgesia, Patient controlled analgesia
- Other
- Lead sponsor
- Rush University Medical Center
- Other
- Eligibility
- Not listed
- Enrollment
- 42 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2013 – 2017
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Stenosis, Spondylolisthesis, Degenerative Disc Disease
- Interventions
- Posterior Lateral Fusion (PLF), Anterior Lumbar Interbody Fusion (ALIF), Transforaminal lumbar interbody fusion (TLIF), Posterior lumbar interbody fusion (PLIF), Extreme lateral interbody fusion (XLIF)
- Procedure
- Lead sponsor
- Exactech
- Industry
- Eligibility
- 21 Years and older
- Enrollment
- 94 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2005 – 2011
- U.S. locations
- 6
- States / cities
- Long Beach, California • San Diego, California • New Hartford, New York + 3 more
- Conditions
- Degenerative Disc Disease Lumbar, Spondylolisthesis, Grade 1
- Interventions
- Device: EVOS Lumbar Interbody System (EVOS-HA)
- Device
- Lead sponsor
- Invibio Ltd
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 22 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019 – 2023
- U.S. locations
- 2
- States / cities
- Charlotte, North Carolina • Philadelphia, Pennsylvania
- Conditions
- Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis
- Interventions
- Trinica Anterior Lumbar Plate System
- Device
- Lead sponsor
- Zimmer Biomet
- Industry
- Eligibility
- Not listed
- Enrollment
- 19 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2008 – 2012
- U.S. locations
- 3
- States / cities
- Daphne, Alabama • Mobile, Alabama • San Bernardino, California
- Conditions
- Spinal Stenosis, Low Back Pain
- Interventions
- Decompressive laminectomy, Non-surgical treatments
- Procedure · Other
- Lead sponsor
- Dartmouth-Hitchcock Medical Center
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 289 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2000 – 2015
- U.S. locations
- 13
- States / cities
- Oakland, California • San Francisco, California • Decatur, Georgia + 9 more
- Conditions
- Degenerative Disc Disease, Degenerative Spondylolisthesis, Spinal Stenosis
- Interventions
- Natural Matrix Protein (NMP) Fibers, Lumbar interbody fusion, Cervical interbody fusion
- Biological · Procedure
- Lead sponsor
- Induce Biologics USA Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Jasper, Alabama
- Conditions
- Lumbar Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis, Spondylosis, Intervertebral Disk Displacement, Intervertebral Disk Degeneration, Spinal Diseases, Bone Diseases, Musculoskeletal Diseases, Spondylolysis
- Interventions
- NuCel, Demineralized Bone Matrix
- Biological
- Lead sponsor
- OhioHealth
- Other
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2014 – 2017
- U.S. locations
- 2
- States / cities
- Columbus, Ohio
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Lumbar Disc Herniation
- Interventions
- Oblique Lateral Lumbar Fusion
- Procedure
- Lead sponsor
- Tristate Brain and Spine Institute
- Other
- Eligibility
- Not listed
- Enrollment
- 303 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2025
- U.S. locations
- 1
- States / cities
- Alexandria, Minnesota
- Conditions
- Pseudoarthrosis, Spinal Stenosis, Spondylolisthesis, Degenerative Disc Disease (DDD)
- Interventions
- Not listed
- Lead sponsor
- Baxano Surgical, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 60 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013 – 2014
- U.S. locations
- 5
- States / cities
- Tampa, Florida • Indianapolis, Indiana • Baton Rouge, Louisiana + 2 more
- Conditions
- Lumbar Disc Disease
- Interventions
- SIGNUS MOBIS PEEK Cage, SIGNUS MOBIS II ST Cage
- Device
- Lead sponsor
- Signus Medizintechnik GmbH
- Industry
- Eligibility
- 18 Years to 89 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- East Syracuse, New York
- Conditions
- Degenerative Disc Disease, Trauma (Including Fractures), Spondylolisthesis
- Interventions
- 1 or 2-Level ACDF utilizing BIO4 with Bio AVS Cervical Allograft (with graft window)., Aviator Anterior Cervical Plating System
- Biological · Device
- Lead sponsor
- Seton Healthcare Family
- Other
- Eligibility
- 19 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2017 – 2020
- U.S. locations
- 1
- States / cities
- Austin, Texas
- Conditions
- Degenerative Disc Disease, Grade 1 Spondylolisthesis
- Interventions
- Spine fusion surgery with Clariance Idys TLIF 3DTi
- Device
- Lead sponsor
- Clariance
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 25 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 1
- States / cities
- College Station, Texas
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Spinal Stenosis
- Interventions
- NeoFuse, posterolateral spinal fusion with instrumentation
- Biological · Procedure
- Lead sponsor
- Mesoblast, Ltd.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 6 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2007 – 2013
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Spinal Stenosis Lumbar
- Interventions
- FIBERGRAFT BG Matrix
- Device
- Lead sponsor
- Prosidyan, Inc.
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 102 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2023
- U.S. locations
- 9
- States / cities
- Long Beach, California • Wellington, Florida • Paducah, Kentucky + 5 more
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Spondylosis
- Interventions
- One or two level lumbar interbody fusion surgery, Nucel
- Procedure · Other
- Lead sponsor
- Organogenesis
- Industry
- Eligibility
- 18 Years to 75 Years
- Enrollment
- 200 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2015 – 2022
- U.S. locations
- 3
- States / cities
- Tampa, Florida • Shreveport, Louisiana • Charlotte, North Carolina
- Conditions
- Spondylolisthesis, Lumbar Region, Spinal Trauma With Neurological Deficit, Degeneration of Lumbar Intervertebral Disc
- Interventions
- Use of Viper Prime/Expedium system with Fibergraft BG Putty
- Device
- Lead sponsor
- Nitin Agarwal
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2024 – 2029
- U.S. locations
- 1
- States / cities
- Pittsburgh, Pennsylvania
- Conditions
- Degenerative Spondylolisthesis
- Interventions
- ART352-L
- Biological
- Lead sponsor
- Ankasa Regenerative Therapeutics, Inc.
- Industry
- Eligibility
- 50 Years and older
- Enrollment
- 12 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2023
- U.S. locations
- 3
- States / cities
- Los Angeles, California • Rochester, Minnesota • Columbus, Ohio
- Conditions
- Degenerative Disc Disease, Spondylolisthesis, Retrolisthesis
- Interventions
- FLXfit™ TLIF Interbody Fusion Device
- Device
- Lead sponsor
- Expanding Orthopedics Ltd.
- Industry
- Eligibility
- 18 Years to 70 Years
- Enrollment
- 30 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2016 – 2018
- U.S. locations
- 1
- States / cities
- Chicago, Illinois
- Conditions
- Degenerative Disc Disease, Spinal Stenosis, Spondylolisthesis, Scoliosis
- Interventions
- ALIF
- Device
- Lead sponsor
- Camber Spine Technologies
- Industry
- Eligibility
- 22 Years to 75 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2020 – 2021
- U.S. locations
- 2
- States / cities
- Philadelphia, Pennsylvania • Plano, Texas