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Showing 1–24 of 47 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Dehiscence Clear all
Completed Not applicable Interventional Results available

Prevention of Seroma Formation and Wound Complications Using NPWT Devices

NCT02147288
View directory record Official record
Conditions
Seroma, Wound Dehiscence, Wound Infection
Interventions
Renasys*GO Negative Pressure Wound Therapy System
Device
Lead sponsor
Yale University
Other
Eligibility
18 Years and older
Enrollment
46 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
New Haven, Connecticut
Source: ClinicalTrials.gov public record
Updated Jan 29, 2017 · Synced Sep 8, 2026, 9:29 PM EDT
Completed Not applicable Interventional Results available

The Role of Antimicrobial Foam Dressing in Prevention of Cesarean Section Wound Complications

NCT03136159
View directory record Official record
Conditions
Cesarean Section; Complications, Wound, Dehiscence
Interventions
Silver-impregnated antimicrobial dressing
Device
Lead sponsor
Loyola University
Other
Eligibility
18 Years to 45 Years · Female only
Enrollment
380 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2019
U.S. locations
1
States / cities
Maywood, Illinois
Source: ClinicalTrials.gov public record
Updated Dec 20, 2020 · Synced Sep 8, 2026, 9:29 PM EDT
Not yet recruiting Not applicable Interventional

Barbed Suture vs Non-Barbed Closure for Emergency Exploratory Laparotomy RCT

NCT06043414
View directory record Official record
Conditions
Laparotomy, Dehiscence Wound, Surgical Site Infections, Trauma Abdomen, Emergency General Surgery
Interventions
triclosan-coated barbed suture, triclosan-coated non-barbed suture, Non-coated non-barbed suture
Device
Lead sponsor
University of Southern California
Other
Eligibility
18 Years to 100 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Nov 27, 2023 · Synced Sep 8, 2026, 9:29 PM EDT
Terminated Not applicable Interventional Results available

Prevention of Wound Complications After Cesarean Delivery in Obese Women Utilizing Negative Pressure Wound Therapy

NCT00654641
View directory record Official record
Conditions
Surgical Wound Dehiscence, Wound Infection
Interventions
Negative pressure wound closure, Standard wound closure
Procedure
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older · Female only
Enrollment
54 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2007 – 2010
U.S. locations
2
States / cities
Charleston, West Virginia • Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated Jan 29, 2013 · Synced Sep 8, 2026, 9:29 PM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Vertical Soft Tissue Augmentation With CTG vs ADM

NCT05729607
View directory record Official record
Conditions
Implant Complication
Interventions
Vertical soft tissue augmentation
Procedure
Lead sponsor
Harvard Medical School (HMS and HSDM)
Other
Eligibility
18 Years to 99 Years
Enrollment
28 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Sep 17, 2025 · Synced Sep 8, 2026, 9:29 PM EDT
Completed Phase 4 Interventional Accepts healthy volunteers Results available

Treatment of Post-Extraction Dehisced Socket - A Case Series Study

NCT02980211
View directory record Official record
Conditions
Tooth Loss
Interventions
Alveolar Ridge Reconstruction
Drug
Lead sponsor
Gustavo Avila-Ortiz DDS, MS, PhD
Other
Eligibility
18 Years and older
Enrollment
17 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 4, 2020 · Synced Sep 8, 2026, 9:29 PM EDT
Withdrawn No phase listed Observational

Study of Avelle™ Negative Pressure Wound Therapy (NPWT) System

NCT05805046
View directory record Official record
Conditions
Surgical Wound, Recent, Surgical Wound Leak, Dehiscence Wound, Trauma-related Wound
Interventions
Negative Pressure Wound Therapy System
Device
Lead sponsor
ConvaTec Inc.
Industry
Eligibility
18 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
4
States / cities
Miami Lakes, Florida • Chicago, Illinois • Lake Success, New York + 1 more
Source: ClinicalTrials.gov public record
Updated Apr 29, 2024 · Synced Sep 8, 2026, 9:29 PM EDT
Not listed No phase listed Observational

Short Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds

NCT03872544
View directory record Official record
Conditions
Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Infection, Wound Complication, Wound Dehiscence, Wound of Skin, Wound Open, Wounds, Penetrating, Wounds, Nonpenetrating, Wounds and Injuries, Wounds, Disturbance of Wound Healing, Facial Bones Fracture, Soft Tissue Injuries, Skull Fractures, Surgical Wound, Surgical Wound Infection, Wound Healing
Interventions
Not listed
Lead sponsor
Dufresne, Craig, MD, PC
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2025
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 15, 2022 · Synced Sep 8, 2026, 9:29 PM EDT
Not listed Not applicable Interventional Accepts healthy volunteers

Split Scar Study to Assess Cosmetic Outcome From Differing Suture Spacing

NCT03284983
View directory record Official record
Conditions
Suture, Complication, Wound, Wound Complication, Wound Dehiscence, Wound of Skin, Surgery, Suture; Complications, Infection or Inflammation
Interventions
Suture spacing for wound closure
Other
Lead sponsor
Silver Falls Dermatology
Other
Eligibility
30 Years to 100 Years
Enrollment
30 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
1
States / cities
Salem, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 14, 2017 · Synced Sep 8, 2026, 9:29 PM EDT
Withdrawn Not applicable Interventional

Managing Wounds With Allevyn Life in a Home Health Care Environment

NCT02776800
View directory record Official record
Conditions
Wounds and Injuries
Interventions
Allevyn Life, Foam dressing with an integrated adhesive border
Device
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
65 Years and older
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
3
States / cities
Tustin, California • Wichita, Kansas • McAllen, Texas
Source: ClinicalTrials.gov public record
Updated Feb 8, 2017 · Synced Sep 8, 2026, 9:29 PM EDT
Not listed No phase listed Observational

Negative Pressure Wound Therapy Registry

NCT02467998
View directory record Official record
Conditions
Diabetic Foot Ulcers, Venous Stasis Ulcer, Pressure Ulcer, Surgical Wound Dehiscence, Burns, Other Types of Chronic Non Healing Wounds
Interventions
NPWT
Device
Lead sponsor
U.S. Wound Registry
Other
Eligibility
Not listed
Enrollment
50,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
Started 2005
U.S. locations
1
States / cities
The Woodlands, Texas
Source: ClinicalTrials.gov public record
Updated Apr 30, 2018 · Synced Sep 8, 2026, 9:29 PM EDT
Completed Not applicable Interventional

The Effect of Vitamin C on Wound Healing In Mandibular Fracture Patients

NCT03938584
View directory record Official record
Conditions
Vitamin C Deficiency, Smoking, Surgery, Surgery--Complications, Wound, Wound Complication, Wound Infection, Wound Dehiscence, Wound of Skin, Mandible Fracture, Mandible Open Fracture, Mandible Closed Fracture, Mandibular Fractures, Ascorbic Acid Deficiency, Oxidative Stress, Inflammation
Interventions
Vitamin C, Placebo
Dietary Supplement · Other
Lead sponsor
Hennepin Healthcare Research Institute
Other
Eligibility
18 Years and older
Enrollment
45 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2021
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jan 25, 2022 · Synced Sep 8, 2026, 9:29 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Vialize Use for the Reduction of Vascular Groin Incisional Dehiscence and Infection

NCT06032949
View directory record Official record
Conditions
Vascular Diseases
Interventions
Vialize
Other
Lead sponsor
University of Florida
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2025
U.S. locations
1
States / cities
Gainesville, Florida
Source: ClinicalTrials.gov public record
Updated Apr 7, 2025 · Synced Sep 8, 2026, 9:29 PM EDT
Recruiting Phase 3 Interventional

Incisional Negative Pressure Wound Therapy to Reduce Infection and Complications in High-Risk Fractures

NCT06337292
View directory record Official record
Conditions
Fracture of Tibia, Wound Heal, Infected Wound, Wound Complication, Wound Dehiscence
Interventions
Incisional Negative Pressure Wound Therapy (NPWT)
Device
Lead sponsor
Major Extremity Trauma Research Consortium
Other
Eligibility
18 Years and older
Enrollment
352 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2028
U.S. locations
6
States / cities
Baltimore, Maryland • Lebanon, New Hampshire • Nashville, Tennessee + 2 more
Source: ClinicalTrials.gov public record
Updated May 11, 2026 · Synced Sep 8, 2026, 9:29 PM EDT
Completed Phase 2 Interventional

Investigation of Subatmospheric Pressure Dressing on Pressure Ulcer Healing

NCT00011531
View directory record Official record
Conditions
Diabetic Foot Ulcers
Interventions
Prevention of Pressure Ulcers
Procedure
Lead sponsor
US Department of Veterans Affairs
Federal
Eligibility
18 Years and older
Enrollment
120 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2000 – 2001
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Feb 8, 2009 · Synced Sep 8, 2026, 9:29 PM EDT
Completed Not applicable Interventional Results available

An RCT Comparing Xenograft and Allograft for Ridge Preservation

NCT02330523
View directory record Official record
Conditions
Tooth Loss
Interventions
allograft + x-link collagen membrane, xenograft + non-x-link collagen
Device
Lead sponsor
McGuire Institute
Industry
Eligibility
18 Years to 70 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Feb 17, 2016 · Synced Sep 8, 2026, 9:29 PM EDT
Completed Not applicable Interventional Results available

EO2 Oxygen Delivery To Study Success Rate of Surgically Closed Wounds

NCT03960463
View directory record Official record
Conditions
Surgical Wound, Diabetes, Amputation Wound, Incision Wound, Peripheral Arterial Disease, Breast Cancer, Diabetic Foot
Interventions
Transcu O2®
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
18 Years to 85 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2024
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jan 22, 2025 · Synced Sep 8, 2026, 9:29 PM EDT
Not listed No phase listed Observational

Long Term Status of Free Dermal Fat Autografts for Complex Craniofacial Wounds

NCT03880188
View directory record Official record
Conditions
Wounds and Injuries, Wound Infection, Facial Bones Fracture, Soft Tissue Injuries, Skull Fractures, Surgical Wound, Surgical Wound Infection, Wound Healing, Disturbance of Wound Healing, Wound; Head, Multiple, Wound; Head, Scalp, Wound; Head, Wound Complication, Wound Dehiscence, Wound of Skin, Wound Open, Wounds, Penetrating, Wounds, Nonpenetrating, Wounds
Interventions
Not listed
Lead sponsor
Dufresne, Craig, MD, PC
Other
Eligibility
Not listed
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Fairfax, Virginia
Source: ClinicalTrials.gov public record
Updated Jun 15, 2022 · Synced Sep 8, 2026, 9:29 PM EDT
Terminated Not applicable Interventional

Acupuncture and Post-Surgical Wound Healing

NCT00260494
View directory record Official record
Conditions
Postoperative Complications, Surgical Wound Infection, Surgical Wound Dehiscence
Interventions
acupuncture, sham acupuncture
Other
Lead sponsor
University of California, San Francisco
Other
Eligibility
18 Years and older
Enrollment
65 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2005 – 2006
U.S. locations
1
States / cities
San Francisco, California
Source: ClinicalTrials.gov public record
Updated Jul 22, 2013 · Synced Sep 8, 2026, 9:29 PM EDT
Not yet recruiting Phase 1 Interventional

Enhancing Wound Perfusion in High-Risk Lower Extremity Orthopaedic Surgery: A Study on Nitropaste Using Intraoperative SPY Imaging.

NCT07004764
View directory record Official record
Conditions
Achilles Tendon Repairs/Reconstructions, Pilon Fracture of Tibia, Tibial Plateau Fracture, Ankle Fracture (Bimalleolar Equivalent, Bimalleolar, or Trimalleolar), Calcaneus Fractures, Talus Fracture, Wound Infection Deep, Wound Infection Post-Traumatic, Wound Dehiscence, Surgical
Interventions
Nitroglycerin Ointment 2%
Drug
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years and older
Enrollment
15 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
2
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Mar 30, 2026 · Synced Sep 8, 2026, 9:29 PM EDT
Completed Not applicable Interventional

A Dual-center Study Evaluating Clinical Acceptance of a NPWT Wound Care System

NCT04593693
View directory record Official record
Conditions
Diabetic Foot Ulcer, Pressure Injury, Pressure Ulcer, Surgical Wound, Acute Wound, Traumatic Wound, Dehiscence, Edema
Interventions
Invia Motion Endure NPWT system
Device
Lead sponsor
Medela AG
Industry
Eligibility
18 Years and older
Enrollment
25 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2021
U.S. locations
2
States / cities
Augusta, Georgia • Austell, Georgia
Source: ClinicalTrials.gov public record
Updated Sep 23, 2021 · Synced Sep 8, 2026, 9:29 PM EDT
Recruiting No phase listed Observational

Myriad™ Augmented Soft Tissue Reconstruction Registry

NCT05243966
View directory record Official record
Conditions
Abdominal Wound Dehiscence, Necrotizing Soft Tissue Infection, Lower Extremity Wound, Pilonidal Sinus, Anal Fistula, Hidradenitis Suppurativa, Pressure Injury
Interventions
Myriad Matrix™ and Myriad Morcells™
Device
Lead sponsor
Aroa Biosurgery Limited
Industry
Eligibility
18 Years and older
Enrollment
800 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2029
U.S. locations
15
States / cities
Phoenix, Arizona • Los Angeles, California • Fort Myers, Florida + 11 more
Source: ClinicalTrials.gov public record
Updated Jul 14, 2026 · Synced Sep 8, 2026, 9:29 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Oxidized Regenerated Cellulose to Decrease Vaginal Cuff Complications

NCT01584128
View directory record Official record
Conditions
Vaginal Cuff Complications
Interventions
Not listed
Lead sponsor
Milton S. Hershey Medical Center
Other
Eligibility
20 Years to 80 Years · Female only
Enrollment
101 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2012 – 2013
U.S. locations
1
States / cities
Hershey, Pennsylvania
Source: ClinicalTrials.gov public record
Updated May 4, 2017 · Synced Sep 8, 2026, 9:29 PM EDT
Recruiting Not applicable Interventional

Steri-Strip Application Versus Standard Wound Closure for Cesarean Section Incisions

NCT07686913
View directory record Official record
Conditions
Cesarean Section, Surgical Site Infection, Wound Dehiscence, Seroma
Interventions
Steri-Strip™ Skin Closures, Standard Cesarean Wound Closure
Device · Procedure
Lead sponsor
Riverside University Health System Medical Center
Other
Eligibility
18 Years and older · Female only
Enrollment
610 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Moreno Valley, California
Source: ClinicalTrials.gov public record
Updated Jul 6, 2026 · Synced Sep 8, 2026, 9:29 PM EDT