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Showing 1–24 of 62 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Deliberate Self-harm Clear all
Not listed Not applicable Interventional Accepts healthy volunteers

Implementing a Brief Suicide Intervention for High Risk Youth With Front-Line Juvenile Justice Staff

NCT02981420
View directory record Official record
Conditions
Suicide and Self Harm
Interventions
Safety planning
Behavioral
Lead sponsor
Rhode Island Hospital
Other
Eligibility
12 Years to 17 Years
Enrollment
300 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Mar 5, 2017 · Synced Jun 10, 2026, 1:26 PM EDT
Completed No phase listed Observational Accepts healthy volunteers Results available

A Study Examining Adolescents With Non-Suicidal Self-Injury

NCT02947308
View directory record Official record
Conditions
Self-Injurious Behavior, Deliberate Self-Harm
Interventions
Not listed
Lead sponsor
University of Minnesota
Other
Eligibility
12 Years to 16 Years · Female only
Enrollment
168 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2023
U.S. locations
3
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Mar 16, 2026 · Synced Jun 10, 2026, 1:26 PM EDT
Active, not recruiting Not applicable Interventional

Comparing Suicide Prevention Interventions to Guide Follow-up Care: The SPRING Trial

NCT06128239
View directory record Official record
Conditions
Suicide, Suicide Prevention, Suicide and Self-harm
Interventions
Caring Contacts
Behavioral
Lead sponsor
St. Luke's Health System, Boise, Idaho
Other
Eligibility
12 Years and older
Enrollment
854 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Boise, Idaho
Source: ClinicalTrials.gov public record
Updated Jul 8, 2025 · Synced Jun 10, 2026, 1:26 PM EDT
Terminated Not applicable Interventional

An Online Intervention to Reduce Self-Harm Among Persons With High Emotion-Related Impulsivity

NCT04781166
View directory record Official record
Conditions
Suicidal Ideation, Deliberate Self-harm, Impulsivity
Interventions
Calm program
Behavioral
Lead sponsor
University of California, Berkeley
Other
Eligibility
13 Years and older
Enrollment
2 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021
U.S. locations
1
States / cities
Berkeley, California
Source: ClinicalTrials.gov public record
Updated Nov 17, 2023 · Synced Jun 10, 2026, 1:26 PM EDT
Withdrawn Not applicable Interventional

College Students Who Self-Harm

NCT02522143
View directory record Official record
Conditions
Borderline Personality Disorder, Suicide
Interventions
Informational sessions describing BPD characteristics, Condensed-DBT treatment intervention
Behavioral
Lead sponsor
University of Minnesota
Other
Eligibility
18 Years to 27 Years
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Jun 19, 2017 · Synced Jun 10, 2026, 1:26 PM EDT
Completed Not applicable Interventional

Randomized Trial to Improve Safe Firearm Storage

NCT05568901
View directory record Official record
Conditions
Firearm Injury, Pediatric Emergency Medicine, Suicide and Self-harm, Mental Health Issue
Interventions
Lethal means counseling, Provision of Cable-style gun locks
Behavioral
Lead sponsor
Children's Hospital Medical Center, Cincinnati
Other
Eligibility
Not listed
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Feb 9, 2023 · Synced Jun 10, 2026, 1:26 PM EDT
Completed Phase 4 Interventional Results available

Treating Suicidal Behavior and Self-Mutilation in People With Borderline Personality Disorder

NCT00533117
View directory record Official record
Conditions
Borderline Personality Disorder
Interventions
Fluoxetine, Dialectical Behavior Therapy, Supportive psychotherapy
Drug · Behavioral
Lead sponsor
New York State Psychiatric Institute
Other
Eligibility
18 Years to 55 Years
Enrollment
91 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2001 – 2012
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 4, 2024 · Synced Jun 10, 2026, 1:26 PM EDT
Completed Not applicable Interventional

Adaptation and Evaluation of the KEEP Model

NCT05816421
View directory record Official record
Conditions
Depression, Anxiety, Post Traumatic Stress Disorder, Suicide and Self-harm, Externalizing Behavior
Interventions
KEEP, Non-Affinity KEEP
Behavioral
Lead sponsor
Oregon Social Learning Center
Other
Eligibility
4 Years to 21 Years
Enrollment
283 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2024
U.S. locations
1
States / cities
Eugene, Oregon
Source: ClinicalTrials.gov public record
Updated Sep 4, 2025 · Synced Jun 10, 2026, 1:26 PM EDT
Completed Phase 2 Interventional Results available

Signatures of N-Ac for Non-Suicidal Self-Injury in Adolescents

NCT04005053
View directory record Official record
Conditions
Self-Harm, Depression, Suicide
Interventions
N-acetyl cysteine, Placebo oral tablet
Drug
Lead sponsor
University of Minnesota
Other
Eligibility
16 Years to 24 Years · Female only
Enrollment
44 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2022
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Aug 14, 2023 · Synced Jun 10, 2026, 1:26 PM EDT
Completed Not applicable Interventional

Randomized Trial of Stepped Care for Suicide Prevention in Teens and Young Adults

NCT03092271
View directory record Official record
Conditions
Suicidal Behavior, Self-Harm, Deliberate, Suicidal Ideation, Suicide
Interventions
Stepped Care for Suicide Prevention, Zero Suicide Quality Improvement
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
12 Years to 24 Years
Enrollment
301 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2022
U.S. locations
2
States / cities
Los Angeles, California • Portland, Oregon
Source: ClinicalTrials.gov public record
Updated Nov 3, 2022 · Synced Jun 10, 2026, 1:26 PM EDT
Completed Not applicable Interventional

Evaluation of a Brief Surf the Urge Intervention

NCT02771886
View directory record Official record
Conditions
Substance Use, Deliberate Self-harm, Trichotillomania, Aggression, Stealing, Eating Pathology, Gambling
Interventions
Surf the Urge
Behavioral
Lead sponsor
Kimberly N Schubert
Other
Eligibility
14 Years to 24 Years
Enrollment
36 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2017
U.S. locations
1
States / cities
Las Vegas, Nevada
Source: ClinicalTrials.gov public record
Updated Apr 3, 2017 · Synced Jun 10, 2026, 1:26 PM EDT
Completed Not applicable Interventional

Mentalization-Based Therapy to Prevent Suicidal Behavior in Adolescents With Bipolar Disorder

NCT02129790
View directory record Official record
Conditions
Bipolar Disorder, Suicidal Ideation
Interventions
Mentalization-Based Therapy
Behavioral
Lead sponsor
University of California, Los Angeles
Other
Eligibility
13 Years to 21 Years
Enrollment
10 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2018
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Apr 17, 2019 · Synced Jun 10, 2026, 1:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Healing Lodge First Face Training Evaluation Study

NCT06290180
View directory record Official record
Conditions
Addiction, Depression/Anxiety, Trauma, Psychological, Self-harm
Interventions
First Face for Mental Heatlh
Behavioral
Lead sponsor
Cambridge Health Alliance
Other
Eligibility
Not listed
Enrollment
92 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Spokane Valley, Washington
Source: ClinicalTrials.gov public record
Updated Dec 1, 2025 · Synced Jun 10, 2026, 1:26 PM EDT
Enrolling by invitation Not applicable Interventional

Advancing Student Suicide Interventions With Scalable Technologies

NCT07211373
View directory record Official record
Conditions
Suicidal Ideation, Suicide Attempt, Self-Harm
Interventions
Jaspr, Behavioral support
Device · Behavioral
Lead sponsor
University of Massachusetts, Amherst
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Amherst, Massachusetts
Source: ClinicalTrials.gov public record
Updated Oct 19, 2025 · Synced Jun 10, 2026, 1:26 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Suicide Classification System

NCT01118156
View directory record Official record
Conditions
Suicide and Self-harm
Interventions
Education
Other
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years and older
Enrollment
74 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2010
U.S. locations
2
States / cities
Denver, Colorado • Grand Junction, Colorado
Source: ClinicalTrials.gov public record
Updated May 2, 2011 · Synced Jun 10, 2026, 1:26 PM EDT
Completed Not applicable Interventional Accepts healthy volunteers

Systems Aligning for Equity (SAFE) Spaces

NCT05658068
View directory record Official record
Conditions
Suicide, Mental Disorder, Mental Health, Burnout, Professional, Self Harm
Interventions
SAFE Spaces training and coaching
Behavioral
Lead sponsor
New York University
Other
Eligibility
Not listed
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jan 6, 2026 · Synced Jun 10, 2026, 1:26 PM EDT
Completed Not applicable Interventional

Examining Feasibility, Acceptability, and Sustainability of a Novel Personalized Smartphone Intervention for Suicide - Randomized Trial

NCT05202756
View directory record Official record
Conditions
Suicide and Self-harm, Suicide, Suicide, Attempted, Suicidal Ideation
Interventions
Mobile Application to Prevent Suicide (MAPS), EMA Monitoring Only
Behavioral
Lead sponsor
Butler Hospital
Other
Eligibility
18 Years to 70 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
2
States / cities
Providence, Rhode Island
Source: ClinicalTrials.gov public record
Updated Sep 4, 2025 · Synced Jun 10, 2026, 1:26 PM EDT
Recruiting Not applicable Interventional

Telehealth Behavioral Activation for Teens

NCT06273995
View directory record Official record
Conditions
Depression, Suicide and Self-harm, Depression in Adolescence, Depression Mild, Depression Moderate, Depression Severe
Interventions
Behavioral Activation
Other
Lead sponsor
Baylor College of Medicine
Other
Eligibility
12 Years to 18 Years
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2029
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Jul 19, 2025 · Synced Jun 10, 2026, 1:26 PM EDT
Active, not recruiting Not applicable Interventional

Adaptive Intervention for Adolescents Following Inpatient Psychiatric Care

NCT05282225
View directory record Official record
Conditions
Suicide, Suicide, Attempted, Suicidal Ideation, Self Harm
Interventions
MI- Safety Plan, Texts messages, Monitoring, Portal follow-up, Booster call
Behavioral
Lead sponsor
University of Michigan
Other
Eligibility
13 Years to 17 Years
Enrollment
300 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2026
U.S. locations
3
States / cities
Ann Arbor, Michigan • Detroit, Michigan • Cincinnati, Ohio
Source: ClinicalTrials.gov public record
Updated Nov 23, 2025 · Synced Jun 10, 2026, 1:26 PM EDT
Not listed Not applicable Interventional

Cognitive Processing Therapy (CPT) for Posttraumatic Stress Disorder and Borderline Personality Disorder (PTSD-BPD)

NCT04230668
View directory record Official record
Conditions
Posttraumatic Stress Disorder, Borderline Personality Disorder
Interventions
Cognitive Processing Therapy with Suicide Risk Management, Treatment as Usual with Suicide Rick Management
Behavioral
Lead sponsor
Palo Alto University
Other
Eligibility
18 Years to 65 Years
Enrollment
33 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2025
U.S. locations
1
States / cities
Palo Alto, California
Source: ClinicalTrials.gov public record
Updated Jan 16, 2024 · Synced Jun 10, 2026, 1:26 PM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Early Study of N-Acetylcysteine to Treat Deliberate Self-Harm in Adolescents

NCT01111734
View directory record Official record
Conditions
Deliberate Self Harm
Interventions
N-Acetylcysteine, fMRI
Dietary Supplement · Drug
Lead sponsor
University of Minnesota
Other
Eligibility
13 Years to 21 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011 – 2015
U.S. locations
1
States / cities
Minneapolis, Minnesota
Source: ClinicalTrials.gov public record
Updated Apr 30, 2019 · Synced Jun 10, 2026, 1:26 PM EDT
Completed No phase listed Observational Accepts healthy volunteers

Executive Dysfunction and Self-Harm Behavior: An Examination of Veterans With TBI, PTSD, or Both

NCT01334463
View directory record Official record
Conditions
Traumatic Brain Injury, Post Traumatic Stress Disorder, Suicide, Self-Injurious Behavior
Interventions
Not listed
Lead sponsor
VA Eastern Colorado Health Care System
Federal
Eligibility
18 Years to 45 Years
Enrollment
186 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2016
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Jan 24, 2016 · Synced Jun 10, 2026, 1:26 PM EDT
Active, not recruiting Not applicable Interventional

Leverage Noninvasive Transcutaneous Vagus Nerve Stimulation to Reduce Suicidal Behaviors in Vulnerable Adolescents

NCT05602779
View directory record Official record
Conditions
Self Harm, Suicidal Ideation
Interventions
tVNS Program, Phone App Program, tVNS and Phone App Program, Sham tNVS and Control App
Device · Other · Combination Product
Lead sponsor
University of Notre Dame
Other
Eligibility
13 Years to 17 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
South Bend, Indiana • Rochester, New York
Source: ClinicalTrials.gov public record
Updated Apr 16, 2026 · Synced Jun 10, 2026, 1:26 PM EDT
Terminated Phase 2 Interventional Results available

Selective Serotonin Reuptake Inhibitors (SSRIs) in Borderline Personality Disorder

NCT01103180
View directory record Official record
Conditions
Borderline Personality Disorder
Interventions
Escitalopram
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years to 40 Years
Enrollment
70 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2014
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Jun 13, 2019 · Synced Jun 10, 2026, 1:26 PM EDT