- Conditions
- Situational Anxiety, Behavior
- Interventions
- Therapy dog presence, Standard-of-care basic behavior guidance
- Behavioral
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 4 Years to 12 Years
- Enrollment
- 25 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2027
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
Search Results
Search by objective public record fields.
Search by query text, NCT ID, condition, intervention, sponsor, city, state, recruitment status, phase, study type, healthy volunteer eligibility, sex, or age. Results are retrieved from ClinicalTrials.gov and synchronized into the directory. Search pages remain noindex by default.
Data is sourced from official ClinicalTrials.gov public API records. Always review the official ClinicalTrials.gov record for the latest information.
Showing 1–24
of 45
matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
- Conditions
- Local Anesthesia Injection Pain
- Interventions
- Local Anesthesia (lidocaine hydrochloride), Iontophoresis of Tetracaine and oxymetazoline
- Drug
- Lead sponsor
- Louisiana State University Health Sciences Center in New Orleans
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- New Orleans, Louisiana
- Conditions
- Anesthesia
- Interventions
- Tetracaine HCl 3% and Oxymetazoline HCl 0.05%, Placebo
- Drug
- Lead sponsor
- St. Renatus, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2013
- U.S. locations
- 3
- States / cities
- Loma Linda, California • Baltimore, Maryland • Philadelphia, Pennsylvania
- Conditions
- Soft Tissue Anesthesia (Numbness)
- Interventions
- NV-101 (phentolamine mesylate solution)
- Drug
- Lead sponsor
- Novalar Pharmaceuticals, Inc.
- Industry
- Eligibility
- 10 Years to 65 Years
- Enrollment
- 122 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2003
- U.S. locations
- 1
- States / cities
- Tacoma, Washington
- Conditions
- Caries,Dental, Apical Periodontitis
- Interventions
- Kovanaze Nasal Spray, Articaine Injection
- Drug
- Lead sponsor
- Virginia Commonwealth University
- Other
- Eligibility
- 6 Years to 18 Years
- Enrollment
- 3 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2019
- U.S. locations
- 1
- States / cities
- Richmond, Virginia
- Conditions
- Anesthesia
- Interventions
- Lidocaine
- Drug
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 18 Years to 30 Years
- Enrollment
- 24 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina
- Conditions
- Anesthesia, Dental
- Interventions
- Phentolamine Mesylate (NV-101)
- Drug
- Lead sponsor
- Novalar Pharmaceuticals, Inc.
- Industry
- Eligibility
- 12 Years and older
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Anesthesia
- Interventions
- Tetracaine HCl 3% and Oxymetazoline HCl 0.05%, Tetracaine HCl 3%, Placebo
- Drug
- Lead sponsor
- St. Renatus, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 110 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2012 – 2013
- U.S. locations
- 3
- States / cities
- Buffalo, New York • Salt Lake City, Utah
- Conditions
- Dental Caries in Children, Dental Diseases, Gastrointestinal Surgery, Procedures Requiring Anesthesia
- Interventions
- Standard Child Life Preparation and Support + Meta Quest 2 VR headset with Gurney Journey (a mixed reality experience), Standard Child Life Preparation and Support
- Device · Behavioral
- Lead sponsor
- Children's Hospital Colorado
- Other
- Eligibility
- 5 Years to 17 Years
- Enrollment
- 58 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2024 – 2025
- U.S. locations
- 1
- States / cities
- Aurora, Colorado
- Conditions
- Anesthetic Effectiveness
- Interventions
- Mandibular buccal Infiltration injection
- Procedure
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 60 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2013
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Anesthesia, Dental
- Interventions
- Phentolamine Mesylate (NV-101)
- Drug
- Lead sponsor
- Novalar Pharmaceuticals, Inc.
- Industry
- Eligibility
- 4 Years to 11 Years
- Enrollment
- 150 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Dental Anesthesia Efficacy
- Interventions
- 3% tetracaine HCL with 0.05% oxymetazoline HCL, Lidocaine Injection
- Drug
- Lead sponsor
- St. Renatus, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 45 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2008 – 2009
- U.S. locations
- 1
- States / cities
- Buffalo, New York
- Conditions
- Pain, Postoperative
- Interventions
- Ibuprofen, Acetominophen
- Drug
- Lead sponsor
- Boston University
- Other
- Eligibility
- 4 Years to 6 Years
- Enrollment
- 75 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2025 – 2027
- U.S. locations
- 1
- States / cities
- Brighton, Massachusetts
- Conditions
- Anesthesia, Dental
- Interventions
- Phentolamine Mesylate (NV-101)
- Drug
- Lead sponsor
- Novalar Pharmaceuticals, Inc.
- Industry
- Eligibility
- 12 Years and older
- Enrollment
- 240 participants
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2006
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Anesthesia, Dental, Pain, Postoperative
- Interventions
- lidocaine, articaine
- Drug
- Lead sponsor
- Boston University
- Other
- Eligibility
- 4 Years to 14 Years
- Healthy volunteers
- Healthy volunteers not accepted
- Timeline
- 2022 – 2023
- U.S. locations
- 1
- States / cities
- Boston, Massachusetts
- Conditions
- Anesthesia
- Interventions
- Kovacaine Mist 0.1 mL x 4 sprays, Kovacaine Mist 0.2 mL x 2 sprays, Kovacaine Mist 0.2 mL x 1 spray
- Drug
- Lead sponsor
- St. Renatus, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 30 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012
- U.S. locations
- 1
- States / cities
- Colorado Springs, Colorado
- Conditions
- Molar Incisor Hypomineralization, Anesthesia, Local
- Interventions
- SDF, Placebo
- Device
- Lead sponsor
- University of Michigan
- Other
- Eligibility
- 6 Years to 11 Years
- Enrollment
- 50 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2027
- U.S. locations
- 1
- States / cities
- Ann Arbor, Michigan
- Conditions
- Pain, Postoperative, Quality of Life
- Interventions
- Bupivacaine Local Anesthetic
- Drug
- Lead sponsor
- NYU College of Dentistry
- Other
- Eligibility
- 18 Years to 85 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2019 – 2024
- U.S. locations
- 1
- States / cities
- New York, New York
- Conditions
- Anesthesia
- Interventions
- 400uL of Kovacaine Mist, 200uL of Kovacaine Mist, 120uL of Kovacaine Mist
- Drug
- Lead sponsor
- St. Renatus, LLC
- Industry
- Eligibility
- 3 Years to 17 Years
- Enrollment
- 48 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012
- U.S. locations
- 1
- States / cities
- Fort Collins, Colorado
- Conditions
- Pain
- Interventions
- mepivacaine + lidocaine followed by lidocaine +lidocaine, lidocaine + lidocaine followed by mepivacaine + lidocaine
- Drug
- Lead sponsor
- Ohio State University
- Other
- Eligibility
- 18 Years to 65 Years
- Enrollment
- 100 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2012 – 2013
- U.S. locations
- 1
- States / cities
- Columbus, Ohio
- Conditions
- Anesthesia
- Interventions
- Tetracaine HCl 3% and Oxymetazoline HCl 0.05%, Placebo spray
- Drug
- Lead sponsor
- St. Renatus, LLC
- Industry
- Eligibility
- 18 Years and older
- Enrollment
- 48 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2011
- U.S. locations
- 1
- States / cities
- Salt Lake City, Utah
- Conditions
- Behavior, Child, Anxiety, Dental
- Interventions
- Virtual Reality, Basic Behavior Guidance Techniques
- Device · Behavioral
- Lead sponsor
- University of Southern California
- Other
- Eligibility
- 6 Years to 18 Years
- Enrollment
- 20 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2023 – 2024
- U.S. locations
- 2
- States / cities
- Long Beach, California • Los Angeles, California
- Conditions
- Endodontic Disease, Post Operative Pain, Symptomatic Irreversible Pulpitis
- Interventions
- Local anesthetic
- Drug
- Lead sponsor
- University of Washington
- Other
- Eligibility
- 18 Years and older
- Enrollment
- 35 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2021 – 2024
- U.S. locations
- 1
- States / cities
- Seattle, Washington
- Conditions
- Anesthesia
- Interventions
- Lidocaine
- Drug
- Lead sponsor
- University of North Carolina, Chapel Hill
- Other
- Eligibility
- 18 Years to 30 Years
- Enrollment
- 23 participants
- Healthy volunteers
- Accepts healthy volunteers
- Timeline
- 2016 – 2017
- U.S. locations
- 1
- States / cities
- Chapel Hill, North Carolina