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Showing 1–24 of 1,308 matching trials from the live ClinicalTrials.gov search.
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Filters: Condition: Dental Anesthesia Clear all
Terminated Phase 4 Interventional Results available

Prospective Trial of the Effect of Preoperative Forced-air Warming on Perioperative Body Temperature Following Neuraxial Anesthesia in Total Hip Arthroplasty Patients

NCT01626690
View directory record Official record
Conditions
Perioperative Hypothermia
Interventions
Bair-Paws Warming Device, Bair-Hugger Warming Device
Device
Lead sponsor
University of Wisconsin, Madison
Other
Eligibility
55 Years to 85 Years
Enrollment
100 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Madison, Wisconsin
Source: ClinicalTrials.gov public record
Updated Aug 14, 2016 · Synced Sep 9, 2026, 12:33 AM EDT
Recruiting No phase listed Observational

Evaluation of Outcomes Following In-office Tympanostomy Using the Tula® System: a Prospective, Multi-center Registry

NCT05915078
View directory record Official record
Conditions
Otitis Media With Effusion, Acute Otitis Media, Otitis Media
Interventions
Iontophoresis and tube placement
Combination Product
Lead sponsor
Smith & Nephew, Inc.
Industry
Eligibility
6 Months to 17 Years
Enrollment
200 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2027
U.S. locations
6
States / cities
Louisville, Kentucky • Cherry Hill, New Jersey • New Brunswick, New Jersey + 3 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2024 · Synced Sep 9, 2026, 12:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Nasal Continuous Positive Airway Pressure Versus Standard Care During Procedural Sedation for Gastrointestinal Endoscopy

NCT03369197
View directory record Official record
Conditions
Hypoxia, Endoscopy, Anesthesia Morbidity
Interventions
Nasal Mask, Control: Nasal Cannula
Device
Lead sponsor
Johns Hopkins University
Other
Eligibility
18 Years to 100 Years
Enrollment
111 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
1
States / cities
Baltimore, Maryland
Source: ClinicalTrials.gov public record
Updated Oct 17, 2022 · Synced Sep 9, 2026, 12:33 AM EDT
Completed Phase 3 Interventional Results available

The Effect of Local Anesthesia on Control of Intraoperative Physiologic Parameters and Post Operative Comfort

NCT04500158
View directory record Official record
Conditions
Pain, Procedural
Interventions
Lidocaine
Drug
Lead sponsor
Virginia Commonwealth University
Other
Eligibility
Up to 6 Years
Enrollment
59 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2020 – 2024
U.S. locations
1
States / cities
Richmond, Virginia
Source: ClinicalTrials.gov public record
Updated Sep 18, 2024 · Synced Sep 9, 2026, 12:33 AM EDT
Completed Phase 3 Interventional Results available

Armodafinil (Nuvigil), Postoperative Recovery of OSA (Obstructive Sleep Apnea) and Obese Patients

NCT02478580
View directory record Official record
Conditions
Obesity, Premature Recovery From Anesthesia
Interventions
Nuvigil, Placebo
Drug
Lead sponsor
University of Texas Southwestern Medical Center
Other
Eligibility
18 Years to 75 Years
Enrollment
67 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2011 – 2016
U.S. locations
1
States / cities
Dallas, Texas
Source: ClinicalTrials.gov public record
Updated Dec 3, 2018 · Synced Sep 9, 2026, 12:33 AM EDT
Completed Phase 3 Interventional Results available

Intranasal Dexmedetomidine Premedication in Children

NCT02250703
View directory record Official record
Conditions
Preoperative Sedation
Interventions
Midazolam, Dexmedetomidine
Drug
Lead sponsor
University of Mississippi Medical Center
Other
Eligibility
5 Years to 18 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
Jackson, Mississippi
Source: ClinicalTrials.gov public record
Updated Jul 6, 2017 · Synced Sep 9, 2026, 12:33 AM EDT
Completed No phase listed Observational

Remifentanil Propofol Infusion in Pediatric Spinal Surgery

NCT00761072
View directory record Official record
Conditions
Spinal Fusion
Interventions
Not listed
Lead sponsor
Children's Hospital of Philadelphia
Other
Eligibility
1 Day to 18 Years
Enrollment
12 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2008 – 2009
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Mar 6, 2013 · Synced Sep 9, 2026, 12:33 AM EDT
Withdrawn Phase 4 Interventional Accepts healthy volunteers

Regional Anesthesia for Head and Neck Reconstruction

NCT04304716
View directory record Official record
Conditions
Pain, Postoperative
Interventions
Regional Anesthesia
Drug
Lead sponsor
University of Florida
Other
Eligibility
18 Years to 90 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
1
States / cities
Jacksonville, Florida
Source: ClinicalTrials.gov public record
Updated Mar 17, 2020 · Synced Sep 9, 2026, 12:33 AM EDT
Completed Not applicable Interventional Results available

Blood Volume Analysis of Total Hip Arthroplasty Patients Under Hypotensive Anesthesia

NCT02148809
View directory record Official record
Conditions
Blood Volume Analysis
Interventions
1mL of I-131 Human Serum Albumin is injected prior to the measurements
Radiation
Lead sponsor
Hospital for Special Surgery, New York
Other
Eligibility
50 Years to 75 Years
Enrollment
14 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2016
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Jun 13, 2017 · Synced Sep 9, 2026, 12:33 AM EDT
Enrolling by invitation No phase listed Observational

A Study to Evaluate Virtual Reality As Adjunct to Anesthesia During Orthopedic Surgery

NCT05112302
View directory record Official record
Conditions
Knee Arthropathy, Hip Injuries
Interventions
Virtual reality
Other
Lead sponsor
Mayo Clinic
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2021 – 2026
U.S. locations
1
States / cities
Jackson, Florida
Source: ClinicalTrials.gov public record
Updated Jan 20, 2026 · Synced Sep 9, 2026, 12:33 AM EDT
Completed Phase 4 Interventional Accepts healthy volunteers

Jet Injection of 1% Buffered Lidocaine Versus Topical ELA-Max for Anesthesia Prior to Intravenous (IV) Catheterization in Children

NCT00444756
View directory record Official record
Conditions
Pain
Interventions
J-tip jet injection of 1% buffered lidocaine
Procedure
Lead sponsor
Norton Healthcare
Other
Eligibility
8 Years to 15 Years
Enrollment
70 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2005 – 2006
U.S. locations
1
States / cities
Louisville, Kentucky
Source: ClinicalTrials.gov public record
Updated Mar 7, 2007 · Synced Sep 9, 2026, 12:33 AM EDT
Completed Phase 3 Interventional

A Safety and Efficacy Study of Dexmedetomidine in Patients Requiring Sedation During Monitored Anesthesia Care (MAC)

NCT00398827
View directory record Official record
Conditions
Anesthesia, Surgical Procedures, Elective
Interventions
Dexmedetomidine, Placebo
Drug
Lead sponsor
Hospira, now a wholly owned subsidiary of Pfizer
Industry
Eligibility
18 Years and older
Enrollment
326 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2006 – 2007
U.S. locations
27
States / cities
Birmingham, Alabama • Loma Linda, California • Miami, Florida + 18 more
Source: ClinicalTrials.gov public record
Updated Jul 22, 2015 · Synced Sep 9, 2026, 12:33 AM EDT
Completed Phase 1 Interventional Accepts healthy volunteers

Evaluation of a Closed-Loop Control System for Administering Patient-Specific Anesthesia

NCT00683956
View directory record Official record
Conditions
Anesthesia, General
Interventions
ReinLoop control software for patient-specific induction and maintenance of anesthesia, Propofol
Device · Drug
Lead sponsor
Stanford University
Other
Eligibility
18 Years to 45 Years
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2009
U.S. locations
1
States / cities
Stanford, California
Source: ClinicalTrials.gov public record
Updated Nov 23, 2011 · Synced Sep 9, 2026, 12:33 AM EDT
Active, not recruiting Phase 4 Interventional

The Effect of General Anesthesia on Pharmacokinetics of Oxycodone in Pediatric

NCT03054831
View directory record Official record
Conditions
Liquid Oxycodone
Interventions
liquid oxycodone
Drug
Lead sponsor
Boston Children's Hospital
Other
Eligibility
2 Years to 8 Years
Enrollment
40 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2027
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 21, 2026 · Synced Sep 9, 2026, 12:33 AM EDT
Terminated No phase listed Observational

Correlation of Bispectral Index Score and Total Intravenous Anesthesia (TIVA)

NCT01618539
View directory record Official record
Conditions
Benign/Malignant Neoplasm, Long Bone Fracture
Interventions
propofol
Drug
Lead sponsor
Rutgers, The State University of New Jersey
Other
Eligibility
18 Years to 65 Years
Enrollment
31 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2014
U.S. locations
1
States / cities
Newark, New Jersey
Source: ClinicalTrials.gov public record
Updated Mar 13, 2017 · Synced Sep 9, 2026, 12:33 AM EDT
Completed No phase listed Observational

Patient Opinions Regarding General Anesthesia, Before and After Having Undergone a Procedure.

NCT05813262
View directory record Official record
Conditions
Anesthesia
Interventions
Not listed
Lead sponsor
Alabama College of Osteopathic Medicine
Other
Eligibility
21 Years and older
Enrollment
217 participants
Timeline
2022
U.S. locations
1
States / cities
Ashford, Alabama
Source: ClinicalTrials.gov public record
Updated Apr 13, 2023 · Synced Sep 9, 2026, 12:33 AM EDT
Recruiting Phase 1 Interventional

Genicular Nerve Block After Open Reduction Internal Fixation of Tibial Plateau

NCT06639503
View directory record Official record
Conditions
Tibial Plateau Fractures
Interventions
Bupivacain
Drug
Lead sponsor
University of Chicago
Other
Eligibility
18 Years and older
Enrollment
38 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2026
U.S. locations
1
States / cities
Chicago, Illinois
Source: ClinicalTrials.gov public record
Updated Feb 4, 2026 · Synced Sep 9, 2026, 12:33 AM EDT
Not listed Not applicable Interventional

Effect of Transpulmonary Pressure Guided Ventilation on Intraoperative Right Heart Function

NCT05709041
View directory record Official record
Conditions
Obesity, Surgery, Anesthesia, Echocardiography, Transesophageal, Mechanical Ventilation
Interventions
Individualized lung-protective ventilation, Standard lung-protective ventilation
Other
Lead sponsor
University of Vermont Medical Center
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023 – 2026
U.S. locations
1
States / cities
Burlington, Vermont
Source: ClinicalTrials.gov public record
Updated Jan 31, 2023 · Synced Sep 9, 2026, 12:33 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

REcovery From DEXmedetomidine-induced Unconsciousness

NCT06003127
View directory record Official record
Conditions
Anesthesia, Healthy, Consciousness, Level Altered
Interventions
Transcranial Magnetic Stimulation-Electroencephalography
Device
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
18 Years to 65 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jan 21, 2026 · Synced Sep 9, 2026, 12:33 AM EDT
Completed No phase listed Observational Accepts healthy volunteers

Clinical Investigation of an Eye-Tracking Device as a Predictor of Delirium in the Recovery Room After Surgery With General Anesthesia

NCT05579093
View directory record Official record
Conditions
Delirium
Interventions
Cognitive test + Pupillary measure
Combination Product
Lead sponsor
Columbia University
Other
Eligibility
18 Years and older
Enrollment
325 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019 – 2021
U.S. locations
1
States / cities
Atlanta, Georgia
Source: ClinicalTrials.gov public record
Updated May 23, 2023 · Synced Sep 9, 2026, 12:33 AM EDT
Terminated Not applicable Interventional Accepts healthy volunteers

Investigating the Effect of Acupressure on Shivering During a Cesarean Delivery in Women Who Were Previously Laboring With an Epidural

NCT03497507
View directory record Official record
Conditions
Shivering, Labor, Cesarean Delivery
Interventions
Sham bracelet, Acupressure bracelet
Device
Lead sponsor
Icahn School of Medicine at Mount Sinai
Other
Eligibility
18 Years to 64 Years · Female only
Enrollment
43 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2021
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Oct 13, 2022 · Synced Sep 9, 2026, 12:33 AM EDT
Recruiting Not applicable Interventional Accepts healthy volunteers

Effect of Silver Diamine Fluoride on Local Anesthesia in Hypomineralized Molars

NCT05964387
View directory record Official record
Conditions
Molar Incisor Hypomineralization, Anesthesia, Local
Interventions
SDF, Placebo
Device
Lead sponsor
University of Michigan
Other
Eligibility
6 Years to 11 Years
Enrollment
50 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2027
U.S. locations
1
States / cities
Ann Arbor, Michigan
Source: ClinicalTrials.gov public record
Updated Feb 11, 2026 · Synced Sep 9, 2026, 12:33 AM EDT
Not listed No phase listed Observational

Tau/P-Tau and Neurocognitive Outcomes in Children

NCT03511729
View directory record Official record
Conditions
General Anesthetics Toxicity, Postoperative Cognitive Dysfunction, Child Development
Interventions
Not listed
Lead sponsor
Massachusetts General Hospital
Other
Eligibility
3 Years to 5 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2018 – 2023
U.S. locations
2
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Apr 24, 2022 · Synced Sep 9, 2026, 12:33 AM EDT
Completed Not applicable Interventional Accepts healthy volunteers Results available

Vibration Analgesia in Propofol Infusion During Anesthesia Induction

NCT03509857
View directory record Official record
Conditions
Pain, Acute
Interventions
BUZZY(tm), No Intervention
Device · Other
Lead sponsor
Montefiore Medical Center
Other
Eligibility
18 Years to 100 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
The Bronx, New York
Source: ClinicalTrials.gov public record
Updated Sep 26, 2022 · Synced Sep 9, 2026, 12:33 AM EDT