Independent directory Public ClinicalTrials.gov records United States
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Showing 25–48 of 24 matching trials from the live ClinicalTrials.gov search.
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Conditions
Pain
Interventions
effervescent ibuprofen tablets, effervescent Aspirin plus Vitamin C tablets, ibuprofen tablets, placebo
Drug
Lead sponsor
Wyeth is now a wholly owned subsidiary of Pfizer
Industry
Eligibility
16 Years to 40 Years
Enrollment
270 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007 – 2008
U.S. locations
1
States / cities
Austin, Texas
Conditions
Determination of Beneficial Effect of Using Enamel Matrix Derivative During Implant Treatment
Interventions
peri-implantitis surgery with enamel matrix derivative
Procedure
Lead sponsor
North Dallas Dental Health
Other
Eligibility
18 Years to 90 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022
U.S. locations
1
States / cities
Dallas, Texas
Completed Phase 2 Interventional Accepts healthy volunteers Results available

A Study of Acetaminophen for Post Surgical Dental Pain

NCT04018612
Conditions
Pain, Postoperative, Dental Pain
Interventions
Acetaminophen, Placebo
Drug · Other
Lead sponsor
Nevakar, Inc.
Industry
Eligibility
17 Years to 55 Years
Enrollment
110 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2019
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Dental Pain
Interventions
Celecoxib 400 mg, Placebo, Indomethacin Test (lower dose), Indomethacin Test (upper dose)
Drug
Lead sponsor
Iroko Pharmaceuticals, LLC
Industry
Eligibility
18 Years to 50 Years
Enrollment
203 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2009
U.S. locations
1
States / cities
Austin, Texas
Conditions
Missing Teeth
Interventions
dental implant placement and immediate provisionalization
Device
Lead sponsor
Harvard Medical School (HMS and HSDM)
Other
Eligibility
20 Years to 80 Years
Enrollment
30 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2026
U.S. locations
1
States / cities
Boston, Massachusetts
Completed Not applicable Interventional Accepts healthy volunteers Results available

Decision Aids for the Management of Suspicious Occlusal Caries Lesions

NCT02340767
Conditions
Dental Caries
Interventions
Spectra Device, DIAGNOdent
Device
Lead sponsor
The National Dental Practice-Based Research Network
Network
Eligibility
6 Years and older
Enrollment
3,085 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2016
U.S. locations
6
States / cities
Birmingham, Alabama • Gainesville, Florida • Minneapolis, Minnesota + 3 more
Conditions
HIV Infections
Interventions
TM HIV, TM HL
Behavioral
Lead sponsor
Boston University
Other
Eligibility
18 Years and older
Enrollment
266 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
2
States / cities
Boston, Massachusetts
Terminated Not applicable Interventional Accepts healthy volunteers Results available

Great Beginnings for Healthy Native Smiles: An Early Childhood Caries Prevention Project

NCT04556175
Conditions
Early Childhood Caries, Dental Caries
Interventions
Oral Health, Healthy Lifestyle
Behavioral
Lead sponsor
Northern Arizona University
Other
Eligibility
18 Years and older
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2022
U.S. locations
2
States / cities
Kykotsmovi, Arizona • Crow Agency, Montana
Completed Not applicable Interventional Accepts healthy volunteers Results available

Outcome Evaluation of Ceramic Crowns Using Two Different Dental Cements

NCT00591942
Conditions
Sensitivity to Dental Cements, Dental Crowns, Dental Three-unit Bridges
Interventions
Full ceramic crowns or 3-unit fixed partial dentures.
Device
Lead sponsor
Clark Stanford
Other
Eligibility
18 Years to 80 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2004 – 2009
U.S. locations
1
States / cities
Iowa City, Iowa
Conditions
Edentulous Jaw
Interventions
T3 short and restoration (prosthesis), T3 standard length and restoration (prosthesis)
Device
Lead sponsor
ZimVie
Industry
Eligibility
18 Years and older
Enrollment
106 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
2
States / cities
Boston, Massachusetts • Dearborn Heights, Michigan
Conditions
Diabetes Type 2, Periodontal Disease, Caries
Interventions
Diabetes Oral Health Program, Stannous Fluoride Dentifrice, Cetylpyridinium Chloride (CPC) and Zinc Lactate Mouthwash
Behavioral · Drug
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years and older
Enrollment
10,000 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
1
States / cities
Long Island City, New York
Completed Phase 3 Interventional Accepts healthy volunteers

Evaluate Onset of Action of a Fast Release Aspirin

NCT01420094
Conditions
Healthy Subjects
Interventions
Acetylsalicyclic acid (Fast release Aspirin, BAY1019036), Acetaminophen (Tylenol extra strength), Placebo
Drug
Lead sponsor
Bayer
Industry
Eligibility
16 Years to 45 Years
Enrollment
510 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2011
U.S. locations
1
States / cities
Salt Lake City, Utah
Conditions
Tooth Loss
Interventions
Sinus lift augmentation and dental implant, Aastrom BRCs
Procedure · Biological
Lead sponsor
University of Michigan
Other
Eligibility
20 Years to 70 Years
Enrollment
26 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2010 – 2013
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed No phase listed Observational Accepts healthy volunteers

Pandemic-adapted Caries Care Multicentre Single-group Interventional Study

NCT04666597
Conditions
Dental Caries in Children
Interventions
Modified CariesCare International management
Procedure
Lead sponsor
Universidad El Bosque, Bogotá
Other
Eligibility
3 Years to 8 Years
Enrollment
409 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2021
U.S. locations
2
States / cities
Indianapolis, Indiana • Boston, Massachusetts
Completed No phase listed Observational Accepts healthy volunteers

Sonographic Imaging of Oral and Dental Anatomical Structures (A Pilot Study)

NCT03657589
Conditions
Ultrasound, Oral Mucosa, Gingival Recession, Alveolar Bone Loss
Interventions
Not listed
Lead sponsor
University of Michigan
Other
Eligibility
18 Years to 99 Years
Enrollment
20 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2018
U.S. locations
1
States / cities
Ann Arbor, Michigan
Completed No phase listed Observational Accepts healthy volunteers

A Meta-analysis Comparing Toothbrushes on Plaque Removal and Gingival Health

NCT05594004
Conditions
Gingivitis, Dental Plaque
Interventions
Oscillating-rotating electric toothbrush, Sonic electric toothbrush, Manual toothbrush
Device
Lead sponsor
Procter and Gamble
Industry
Eligibility
18 Years and older
Enrollment
2,929 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022
U.S. locations
1
States / cities
Cincinnati, Ohio
Completed Not applicable Interventional Accepts healthy volunteers

Orthodontic Varnish Microbiology Study

NCT04528134
Conditions
Dental Caries, Dental Plaque, Dental White Spot
Interventions
Extended Contact RMGI (Resin-modified Glass Ionomer) Varnish, 5% Sodium Fluoride Varnish
Device
Lead sponsor
University of California, Los Angeles
Other
Eligibility
12 Years to 27 Years
Enrollment
38 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Los Angeles, California
Completed Phase 3 Interventional Accepts healthy volunteers Results available

Clinical Research Study Efficacy of a Prototype Oral Rinse

NCT01021007
Conditions
Dental Plaque
Interventions
Iodine, water
Drug · Other
Lead sponsor
Colgate Palmolive
Industry
Eligibility
18 Years to 65 Years
Enrollment
67 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2007
U.S. locations
1
States / cities
Northfield, New Jersey
Conditions
Autism Spectrum Disorder, Dental Caries
Interventions
video modeled social story
Behavioral
Lead sponsor
Yale University
Other
Eligibility
5 Years to 14 Years
Enrollment
19 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2014 – 2015
U.S. locations
2
States / cities
New Haven, Connecticut
Conditions
Dental Caries
Interventions
C16G2
Drug
Lead sponsor
Armata Pharmaceuticals, Inc.
Industry
Eligibility
18 Years to 75 Years
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2015
U.S. locations
2
States / cities
Kalispell, Montana • Salt Lake City, Utah
Active, not recruiting No phase listed Observational Accepts healthy volunteers

Survival of Implant-Supported All-Ceramic Prostheses

NCT01729858
Conditions
Partial Edentulism, Disorder of Prostheses and Implants, Dental Prosthesis Failure
Interventions
Ceramic-Ceramic, Metal-Ceramic
Device
Lead sponsor
University of Florida
Other
Eligibility
21 Years to 75 Years
Enrollment
106 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2028
U.S. locations
1
States / cities
Gainesville, Florida
Conditions
Dental Caries
Interventions
Ferumoxytol/Hydrogen peroxide, Hydrogen Peroxide, Water
Drug
Lead sponsor
University of Pennsylvania
Other
Eligibility
18 Years to 85 Years
Enrollment
16 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
2
States / cities
Indianapolis, Indiana • Philadelphia, Pennsylvania
Completed Early Phase 1 Interventional Accepts healthy volunteers

Tissue Characterization in Teeth Treated With a Regeneration Protocol

NCT00881907
Conditions
Pulp Necrosis
Interventions
Triple Antibiotic Paste
Drug
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
10 Years to 60 Years
Enrollment
1 participant
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2014
U.S. locations
1
States / cities
San Antonio, Texas
Conditions
Asthma, Dental Caries
Interventions
Chinese Licorice Root
Dietary Supplement
Lead sponsor
University of Nebraska
Other
Eligibility
4 Years to 16 Years
Enrollment
39 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2009 – 2011
U.S. locations
1
States / cities
Omaha, Nebraska