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ClinicalTrials.gov public records Last synced Nov 13, 2026, 2:32 PM EST

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Showing 1–24 of 33 matching trials from the live ClinicalTrials.gov search.
Filters: Condition: Dental Fear Clear all
Recruiting Not applicable Interventional

Study of Anxiety Free Experiences at the Dentist

NCT07931131
View directory record Official record
Conditions
Dental Phobia, Dental Anxiety in Children, Dental Fear, Dental Fear and Anxiety
Interventions
One-Session Treatment for Dental Phobia (OSTD), Psychoeducation and Relaxation Training (RELAX)
Behavioral
Lead sponsor
University of Texas Rio Grande Valley
Other
Eligibility
7 Years to 16 Years
Enrollment
160 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2030
U.S. locations
2
States / cities
Brownsville, Texas • Edinburg, Texas
Source: ClinicalTrials.gov public record
Updated Nov 12, 2026 · Synced Nov 13, 2026, 2:32 PM EST
Terminated Not applicable Interventional Accepts healthy volunteers

Do Therapy Dogs Improve Behavior and Reduce Anxiety in Pediatric Dental Patients?

NCT06057090
View directory record Official record
Conditions
Therapy Animals, Dental Anxiety, Child Behavior, Anesthesia, Local
Interventions
Therapy Dog
Behavioral
Lead sponsor
Medical University of South Carolina
Other
Eligibility
3 Years to 7 Years
Enrollment
41 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2026
U.S. locations
1
States / cities
Charleston, South Carolina
Source: ClinicalTrials.gov public record
Updated May 4, 2026 · Synced Nov 13, 2026, 2:32 PM EST
Completed Not applicable Interventional Results available

Efficacy of an Internet-based Intervention for Dental Anxiety

NCT03680755
View directory record Official record
Conditions
Dental Anxiety
Interventions
Internet-based intervention for dental anxiety
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 75 Years
Enrollment
503 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2024
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Aug 17, 2025 · Synced Nov 13, 2026, 2:32 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Effects of Virtual Reality Relaxation on the Anxiety Levels

NCT06804967
View directory record Official record
Conditions
Anxiety
Interventions
virtual reality relaxation headset
Device
Lead sponsor
Indiana University
Other
Eligibility
13 Years and older
Enrollment
62 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2026
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Apr 7, 2026 · Synced Nov 13, 2026, 2:32 PM EST
Not yet recruiting Not applicable Interventional

Feasibility of a Modified Dental Comfort Position for Pediatric Patients Receiving Dental Exams

NCT07798141
View directory record Official record
Conditions
Dental Anxiety in Children, Feasibility Studies, Comfort
Interventions
Modified Bottom-to-Bottom Comfort Position
Other
Lead sponsor
Children's Hospital Colorado
Other
Eligibility
12 Months to 5 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Denver, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 1, 2026 · Synced Nov 13, 2026, 2:32 PM EST
Active, not recruiting Not applicable Interventional

Virtual Reality Exposure for Dental Fear

NCT06494176
View directory record Official record
Conditions
Dental Fear
Interventions
neVR Fear the Dentist
Behavioral
Lead sponsor
New York University
Other
Eligibility
13 Years and older
Enrollment
250 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2027
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Mar 11, 2026 · Synced Nov 13, 2026, 2:32 PM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Tactile Pre-Visit Imagery

NCT07719205
View directory record Official record
Conditions
Dental Anxiety in Children, Behavior Change
Interventions
Tactile Previsit Imagery Booklet
Behavioral
Lead sponsor
University of Southern California
Other
Eligibility
4 Years to 10 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2026 – 2028
U.S. locations
2
States / cities
Los Angeles, California • Santa Ana, California
Source: ClinicalTrials.gov public record
Updated Jul 22, 2026 · Synced Nov 13, 2026, 2:32 PM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

A Stepped Care Approach to Treating Dental Fear

NCT06024395
View directory record Official record
Conditions
Dental Fear
Interventions
A stepped-care approach to the treatment of dental fear; Dental Fearless
Behavioral
Lead sponsor
New York University
Other
Eligibility
13 Years to 99 Years
Enrollment
1,000 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2023 – 2028
U.S. locations
1
States / cities
New York, New York
Source: ClinicalTrials.gov public record
Updated Aug 3, 2026 · Synced Nov 13, 2026, 2:32 PM EST
Completed Not applicable Interventional

Evaluating Sensory-Adapted Dental Care in Children With Sensory Processing Disorders

NCT06411808
View directory record Official record
Conditions
Sensory Processing Disorder
Interventions
Sensory-Adapted Dental Environment
Behavioral
Lead sponsor
The University of Texas Health Science Center at San Antonio
Other
Eligibility
2 Years to 17 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2024 – 2025
U.S. locations
1
States / cities
San Antonio, Texas
Source: ClinicalTrials.gov public record
Updated May 6, 2026 · Synced Nov 13, 2026, 2:32 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Smartphone-Based Exposure Treatment for Dental Anxiety

NCT03461016
View directory record Official record
Conditions
Phobic Disorders, Dental Anxiety, Treatment Outcome
Interventions
Exposure Therapy
Behavioral
Lead sponsor
West Virginia University
Other
Eligibility
18 Years and older
Enrollment
37 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2018
U.S. locations
1
States / cities
Morgantown, West Virginia
Source: ClinicalTrials.gov public record
Updated May 26, 2020 · Synced Nov 13, 2026, 2:32 PM EST
Completed Not applicable Interventional Results available

Clinical Management of Anxiety and Access to Health Care

NCT02081365
View directory record Official record
Conditions
Dental Anxiety
Interventions
Computerized Dental Anxiety Treatment
Behavioral
Lead sponsor
Temple University
Other
Eligibility
18 Years to 70 Years
Enrollment
151 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2013 – 2014
U.S. locations
1
States / cities
Philadelphia, Pennsylvania
Source: ClinicalTrials.gov public record
Updated Jan 27, 2017 · Synced Nov 13, 2026, 2:32 PM EST
Not yet recruiting Not applicable Interventional

Music Therapy to Improve Dental Procedure Tolerance and Reduce Distress in Adults With Intellectual and Developmental Differences

NCT07806201
View directory record Official record
Conditions
Intellectual and Developmental Differences, Dental Anxiety
Interventions
Live Music Therapy, Recorded Music
Behavioral
Lead sponsor
University of Rochester
Other
Eligibility
18 Years and older
Enrollment
50 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2027
U.S. locations
1
States / cities
Rochester, New York
Source: ClinicalTrials.gov public record
Updated Sep 25, 2026 · Synced Nov 13, 2026, 2:32 PM EST
Completed Not applicable Interventional Results available

Comparing Brief Relaxation Period to Virtual Reality Period in Reducing Dental Anxiety Prior to Root Canal Treatment

NCT05720897
View directory record Official record
Conditions
Dental Anxiety
Interventions
Auditory Alone, Relaxation Virtual Reality
Other · Device
Lead sponsor
Indiana University
Other
Eligibility
18 Years to 90 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2023
U.S. locations
1
States / cities
Indianapolis, Indiana
Source: ClinicalTrials.gov public record
Updated Sep 19, 2024 · Synced Nov 13, 2026, 2:32 PM EST
Not listed Phase 4 Interventional

Nitrous Oxide Prior to Intranasal Midazolam for Moderate Dental Sedation in Pediatric Patients

NCT04083105
View directory record Official record
Conditions
Dental Anxiety, Pain
Interventions
Nitrous Oxide, Midazolam
Drug
Lead sponsor
Children's Hospital Colorado
Other
Eligibility
3 Years to 8 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2021
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Sep 10, 2019 · Synced Nov 13, 2026, 2:32 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Dental Fear Among Children With Autism Spectrum Disorders

NCT01784276
View directory record Official record
Conditions
Dental Fear
Interventions
Video
Behavioral
Lead sponsor
Boston Children's Hospital
Other
Eligibility
7 Years to 17 Years
Enrollment
80 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2010 – 2012
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Feb 5, 2013 · Synced Nov 13, 2026, 2:32 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

Computer Assisted Relaxation Learning for Dental Offices

NCT00609648
View directory record Official record
Conditions
Dental Anxiety
Interventions
Computer Assisted Relaxation Learning, Pamphlet
Behavioral
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
84 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2008 – 2010
U.S. locations
5
States / cities
Corvallis, Oregon • West Linn, Oregon • Bremerton, Washington + 2 more
Source: ClinicalTrials.gov public record
Updated Feb 20, 2013 · Synced Nov 13, 2026, 2:32 PM EST
Completed Phase 3 Interventional Results available

A Comparison of Oral Sedation-related Events of Three Multiagent Oral Sedation Regimens in Pediatric Dental Patients

NCT05126459
View directory record Official record
Conditions
Anxiety, Dental, Dental Decay
Interventions
Regimen 1, Regimen #2, Regimen #3
Combination Product
Lead sponsor
Loma Linda University
Other
Eligibility
3 Years to 7 Years
Enrollment
60 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2023
U.S. locations
1
States / cities
Loma Linda, California
Source: ClinicalTrials.gov public record
Updated Oct 2, 2024 · Synced Nov 13, 2026, 2:32 PM EST
Terminated Not applicable Interventional

Reducing Anxiety in Pediatric Dental Patients Through Passive Music Therapy

NCT03943836
View directory record Official record
Conditions
Anxiety, Dental
Interventions
Music
Behavioral
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
9 Years to 17 Years
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2020
U.S. locations
1
States / cities
Houston, Texas
Source: ClinicalTrials.gov public record
Updated Apr 11, 2022 · Synced Nov 13, 2026, 2:32 PM EST
Completed Not applicable Interventional Accepts healthy volunteers

The Use of Virtual Reality Goggles

NCT03486717
View directory record Official record
Conditions
Dental Anxiety
Interventions
Virtual reality goggles
Device
Lead sponsor
Casey Goetz
Other
Eligibility
8 Years to 12 Years
Enrollment
7 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
1
States / cities
Iowa City, Iowa
Source: ClinicalTrials.gov public record
Updated Feb 15, 2019 · Synced Nov 13, 2026, 2:32 PM EST
Recruiting Not applicable Interventional Accepts healthy volunteers

Sensory Adapted Dental Environments to Enhance Oral Care for Children With and Without Dental Fear and Anxiety

NCT06912854
View directory record Official record
Conditions
Dental Fear and Anxiety
Interventions
Sensory Adapted Dental Environment, Video-based Modeling
Other
Lead sponsor
University of Southern California
Other
Eligibility
6 Years to 12 Years
Enrollment
312 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2025 – 2029
U.S. locations
1
States / cities
Los Angeles, California
Source: ClinicalTrials.gov public record
Updated Oct 2, 2025 · Synced Nov 13, 2026, 2:32 PM EST
Completed Not applicable Interventional Results available

Nonpharmacologic Reduction of Periprocedural Distress and Drug Use

NCT03328208
View directory record Official record
Conditions
Dental Anxiety, Dental Pain, Drug Use, Opioid Use
Interventions
Comfort Talk® app, White Noise app
Other
Lead sponsor
Hypnalgesics, LLC
Industry
Eligibility
18 Years and older
Enrollment
72 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2017 – 2018
U.S. locations
2
States / cities
Boston, Massachusetts • Brookline, Massachusetts
Source: ClinicalTrials.gov public record
Updated Nov 30, 2021 · Synced Nov 13, 2026, 2:32 PM EST
Completed No phase listed Observational Accepts healthy volunteers

Examining Stress Salivary Biomarkers in Pediatric Patients Undergoing Dental Procedures

NCT06730425
View directory record Official record
Conditions
Dental Anxiety, Dental Fear, Stress, Pediatric Population
Interventions
Not listed
Lead sponsor
Midwestern University
Other
Eligibility
7 Years to 17 Years
Enrollment
66 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2025
U.S. locations
1
States / cities
Downers Grove, Illinois
Source: ClinicalTrials.gov public record
Updated Aug 17, 2025 · Synced Nov 13, 2026, 2:32 PM EST
Not listed Not applicable Interventional Accepts healthy volunteers

The Impact of Medical Play in the Dental Clinic Setting on the Cooperation of Neurotypical Patients

NCT05571423
View directory record Official record
Conditions
Dental Phobia, Dental Anxiety, Oral Aversion
Interventions
Medical Play, Routine Play
Behavioral
Lead sponsor
University of Colorado, Denver
Other
Eligibility
5 Years to 10 Years
Enrollment
100 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2025
U.S. locations
1
States / cities
Aurora, Colorado
Source: ClinicalTrials.gov public record
Updated Feb 1, 2024 · Synced Nov 13, 2026, 2:32 PM EST
Withdrawn Not applicable Interventional Accepts healthy volunteers

Effectiveness of Synapse Transcutaneous Electronic Nerve Stimulation (TENS) During Dental Procedures Among Children

NCT03779659
View directory record Official record
Conditions
Dental Fear, Anesthesia, Local, Pediatric Dentistry
Interventions
Synapse TENS device, Topical anesthetic gel
Device · Drug
Lead sponsor
Boston University
Other
Eligibility
6 Years to 14 Years
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
1
States / cities
Boston, Massachusetts
Source: ClinicalTrials.gov public record
Updated Jun 8, 2021 · Synced Nov 13, 2026, 2:32 PM EST