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Showing 1–24 of 50 matching trials from the live ClinicalTrials.gov search.
Local D1 index available.
Conditions
Malocclusion
Interventions
interceptive orthodontic treatments
Procedure
Lead sponsor
University of Washington
Other
Eligibility
8 Years to 11 Years
Enrollment
150 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2003 – 2009
U.S. locations
1
States / cities
Seattle, Washington
Completed Not applicable Interventional Accepts healthy volunteers Results available

BRIUS Vs FFA Efficiency

NCT04347018
Conditions
Dental Malocclusion, Angle Class II, Angle Class I, Crowding, Tooth
Interventions
BRIUS
Device
Lead sponsor
State University of New York at Buffalo
Other
Eligibility
10 Years to 17 Years
Enrollment
13 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2020 – 2022
U.S. locations
1
States / cities
Buffalo, New York
Completed Not applicable Interventional Accepts healthy volunteers Results available

The Use of Clear Aligners With Movement Enhancement Techniques

NCT02087163
Conditions
Malocclusion
Interventions
Movement Enhancement Technique, Clear Aligner
Device
Lead sponsor
Align Technology, Inc.
Industry
Eligibility
16 Years to 46 Years
Enrollment
90 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2014 – 2019
U.S. locations
1
States / cities
San Jose, California
Conditions
Surgical Complication, Paresthesia, Fracture, Nerve Injury, Nerve Entrapments, Mandibular Nerve Injuries, Mandibular Hypoplasia, Mandibular Retrognathism, Mandibular Hyperplasia, Mandibular Prognathism
Interventions
Sonopet ultrasonic saw, Reciprocating saw
Device
Lead sponsor
University of California, San Francisco
Other
Eligibility
Up to 45 Years
Enrollment
32 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2023
U.S. locations
2
States / cities
San Francisco, California
Conditions
Osteogenesis Imperfecta
Interventions
Invisalign
Device
Lead sponsor
Baylor College of Medicine
Other
Eligibility
12 Years to 40 Years
Enrollment
57 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2022 – 2027
U.S. locations
2
States / cities
Los Angeles, California • Bethesda, Maryland
Conditions
Malocclusion
Interventions
SureSmile® Clear Aligners
Device
Lead sponsor
Dentsply Sirona Implants and Consumables
Industry
Eligibility
18 Years and older
Enrollment
90 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2026 – 2028
U.S. locations
4
States / cities
Fresno, California • Princeton Junction, New Jersey • Huntersville, North Carolina + 1 more
Not listed No phase listed Observational Accepts healthy volunteers

EXD-959 Orthodontic Brackets and EXD-961 Related Instruments Trial

NCT03606551
Conditions
Malocclusion
Interventions
EXD-959 Bracket System
Device
Lead sponsor
3M
Industry
Eligibility
11 Years and older
Enrollment
78 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018 – 2022
U.S. locations
5
States / cities
Culver City, California • Wellington, Florida • Northfield, Minnesota + 2 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Assessment of the Efficacy of the Aerodentis System

NCT03421886
Conditions
Orthodontic Treatment, Tooth Crowding, Orthodontics
Interventions
Aerodentis system, Invisalign clear aligner system
Device
Lead sponsor
University of Alabama at Birmingham
Other
Eligibility
12 Years to 60 Years
Enrollment
45 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2020
U.S. locations
1
States / cities
Birmingham, Alabama
Conditions
Malocclusion, Misaligned Teeth
Interventions
Clear Aligners with Dental Monitoring, Clear Aligners
Device
Lead sponsor
University of Illinois at Chicago
Other
Eligibility
12 Years to 70 Years
Enrollment
12 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2022 – 2027
U.S. locations
4
States / cities
Antioch, Illinois • Chicago, Illinois • Grayslake, Illinois + 1 more
Conditions
Malocclusion
Interventions
OrthoPulse™
Device
Lead sponsor
Biolux Research Holdings, Inc.
Industry
Eligibility
11 Years to 40 Years
Enrollment
20 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2012 – 2013
U.S. locations
1
States / cities
Suwanee, Georgia
Completed Not applicable Interventional Accepts healthy volunteers

Effect of VPro5 Therapy on Clear Aligner Therapy

NCT03240770
Conditions
Malocclusion
Interventions
VPro5 device, Deviation from Standard Tray Wear Time (14 Days)
Device · Other
Lead sponsor
Mani Alikhani
Industry
Eligibility
18 Years to 45 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017
U.S. locations
4
States / cities
Hoboken, New Jersey • Brooklyn, New York • San Antonio, Texas
Conditions
Malocclusion
Interventions
Fixed Appliance Orthodontic Treatment, OrthoPulse™
Device
Lead sponsor
Biolux Research Holdings, Inc.
Industry
Eligibility
11 Years to 60 Years
Enrollment
10 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
3
States / cities
Chandler, Arizona • Peoria, Arizona • Phoenix, Arizona
Completed Not applicable Interventional Accepts healthy volunteers Results available

Analysis of Orthodontic Tooth Movement Using 3D Imaging

NCT03398798
Conditions
Tooth Crowding, Dental Crowding, Malocclusion
Interventions
.014", .016", Twin brackets, Self-ligating brackets
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
10 Years to 45 Years
Enrollment
36 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2018
U.S. locations
2
States / cities
Chapel Hill, North Carolina • Huntersville, North Carolina
Active, not recruiting No phase listed Observational

Dental Malocclusion and Craniofacial Development in OI

NCT02934451
Conditions
Osteogenesis Imperfecta
Interventions
Not listed
Lead sponsor
Baylor College of Medicine
Other
Eligibility
10 Years to 100 Years
Enrollment
75 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2027
U.S. locations
2
States / cities
Los Angeles, California • Houston, Texas
Not listed Not applicable Interventional Accepts healthy volunteers

OrthoPulse 2.0 and 2.1 Feasibility Evaluation

NCT03683017
Conditions
Malocclusion
Interventions
OrthoPulse 2.0, OrthoPulse 2.1, Invisalign 3.5 Day Wear, Fixed Orthodontic Appliances (Braces)
Device
Lead sponsor
Biolux Research Holdings, Inc.
Industry
Eligibility
11 Years and older
Enrollment
35 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2020
U.S. locations
6
States / cities
Chandler, Arizona • Peoria, Arizona • Phoenix, Arizona + 3 more
Completed Not applicable Interventional Accepts healthy volunteers Results available

Evaluation of Clear Aligner Trays to Straighten Teeth

NCT03141788
Conditions
Malocclusion
Interventions
Clear Aligner
Device
Lead sponsor
Solventum Orthodontics Corporation
Industry
Eligibility
14 Years and older
Enrollment
52 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2017 – 2019
U.S. locations
9
States / cities
Denver, Colorado • Kennesaw, Georgia • Catonsville, Maryland + 5 more
Conditions
Tooth Crowding
Interventions
Light Force (150g Niti Coil), Heavy Force (400 g Niti coil)
Device
Lead sponsor
UConn Health
Other
Eligibility
11 Years to 16 Years
Enrollment
40 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2024 – 2028
U.S. locations
1
States / cities
Farmington, Connecticut
Conditions
Malocclusion, Angle Class I
Interventions
Surgically facilitated orthodontics therapy (SFOT) using allograft, Surgically facilitated orthodontics therapy (SFOT) using xenograft, Usual care
Device
Lead sponsor
The University of Texas Health Science Center, Houston
Other
Eligibility
18 Years and older
Enrollment
24 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2025 – 2027
U.S. locations
1
States / cities
Houston, Texas
Conditions
Tooth Movement, Malocclusion
Interventions
AcceleDent, Vibrational Device
Device
Lead sponsor
University of Washington
Other
Eligibility
18 Years and older
Enrollment
27 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2015 – 2017
U.S. locations
1
States / cities
Seattle, Washington
Conditions
Malocclusion
Interventions
AcceleDent Aura, Accelerated Invisalign therapy
Device
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
18 Years to 99 Years
Enrollment
34 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2016 – 2019
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Suspended No phase listed Observational Accepts healthy volunteers

Premolar Extractions for Obstructive Sleep Apnea in Children With Overjet

NCT04946201
Conditions
Obstructive Sleep Apnea, Malocclusion
Interventions
Not listed
Lead sponsor
Mohamed Bazina
Other
Eligibility
10 Years to 15 Years
Enrollment
60 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2021 – 2026
U.S. locations
1
States / cities
Lexington, Kentucky
Conditions
Malocclusion
Interventions
Invisalign (7 day), Invisalign (5 day), OrthoPulse, Invisalign (3.5 day)
Device
Lead sponsor
Biolux Research Holdings, Inc.
Industry
Eligibility
18 Years and older
Enrollment
167 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2016 – 2019
U.S. locations
4
States / cities
Chandler, Arizona • Maple Grove, Minnesota • Henderson, Nevada + 1 more
Conditions
Dentofacial Abnormalities, Dentofacial Deformities, Dentofacial Anomalies, Including Malocclusion, Malocclusion, Malocclusion in Children, Dentofacial Disharmony, Skeletal Malocclusion, Skeletal Malformation, Speech Sound Disorder, Speech Disorders
Interventions
Orthognathic surgery and Orthodontics
Other
Lead sponsor
University of North Carolina, Chapel Hill
Other
Eligibility
15 Years to 40 Years
Enrollment
180 participants
Healthy volunteers
Healthy volunteers not accepted
Timeline
2019 – 2026
U.S. locations
1
States / cities
Chapel Hill, North Carolina
Completed Not applicable Interventional Accepts healthy volunteers Results available

Class II Correction Study Using the Invisalign System

NCT02376829
Conditions
Malocclusion
Interventions
Invisalign System
Device
Lead sponsor
Align Technology, Inc.
Industry
Eligibility
11 Years to 19 Years
Enrollment
164 participants
Healthy volunteers
Accepts healthy volunteers
Timeline
2015 – 2021
U.S. locations
8
States / cities
Scottsdale, Arizona • Rocklin, California • Roseville, California + 5 more